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Items: 1 to 50 of 69

1.

Correction to: The SRCIN1/p140Cap adaptor protein negatively regulates the aggressiveness of neuroblastoma.

Grasso S, Cangelosi D, Chapelle J, Alzona M, Centonze G, Lamolinara A, Salemme V, Angelini C, Morellato A, Saglietto A, Bianchi FT, Cabodi S, Salaroglio IC, Fusella F, Ognibene M, Iezzi M, Pezzolo A, Poli V, Di Cunto F, Eva A, Riganti C, Varesio L, Turco E, Defilippi P.

Cell Death Differ. 2019 Sep 5. doi: 10.1038/s41418-019-0405-7. [Epub ahead of print]

PMID:
31488891
2.

The SRCIN1/p140Cap adaptor protein negatively regulates the aggressiveness of neuroblastoma.

Grasso S, Cangelosi D, Chapelle J, Alzona M, Centonze G, Lamolinara A, Salemme V, Angelini C, Morellato A, Saglietto A, Bianchi FT, Cabodi S, Salaroglio IC, Fusella F, Ognibene M, Iezzi M, Pezzolo A, Poli V, Di Cunto F, Eva A, Riganti C, Varesio L, Turco E, Defilippi P.

Cell Death Differ. 2019 Jul 8. doi: 10.1038/s41418-019-0386-6. [Epub ahead of print] Erratum in: Cell Death Differ. 2019 Sep 5;:.

PMID:
31285546
3.

Precision Revisited: Targeting Microcephaly Kinases in Brain Tumors.

Pallavicini G, Berto GE, Di Cunto F.

Int J Mol Sci. 2019 Apr 28;20(9). pii: E2098. doi: 10.3390/ijms20092098. Review.

4.

Citron kinase interacts with LATS2 and inhibits its activity by occluding its hydrophobic phosphorylation motif.

Tran THY, Yang DW, Kim M, Lee DH, Gai M, Di Cunto F, Choi KW, Lim DS.

J Mol Cell Biol. 2019 Mar 13. pii: mjz013. doi: 10.1093/jmcb/mjz013. [Epub ahead of print]

PMID:
30865227
5.

p53-Sensitive Epileptic Behavior and Inflammation in Ft1 Hypomorphic Mice.

Burla R, La Torre M, Zanetti G, Bastianelli A, Merigliano C, Del Giudice S, Vercelli A, Di Cunto F, Boido M, Vernì F, Saggio I.

Front Genet. 2018 Nov 27;9:581. doi: 10.3389/fgene.2018.00581. eCollection 2018.

6.

Correction to: ZIKA virus elicits P53 activation and genotoxic stress in human neural progenitors similar to mutations involved in severe forms of genetic microcephaly.

El Ghouzzi V, Bianchi FT, Molineris I, Mounce BC, Berto GE, Rak M, Lebon S, Aubry L, Tocco C, Gai M, Chiotto AMA, Sgrò F, Pallavicini G, Simon-Loriere E, Passemard S, Vignuzzi M, Gressens P, Di Cunto F.

Cell Death Dis. 2018 Nov 20;9(12):1155. doi: 10.1038/s41419-018-1159-8.

7.

A novel p.Ser108LeufsTer15 SOD1 mutation leading to the formation of a premature stop codon in an apparently sporadic ALS patient: insights into the underlying pathomechanisms.

Canosa A, De Marco G, Lomartire A, Rinaudo MT, Di Cunto F, Turco E, Barberis M, Brunetti M, Casale F, Moglia C, Calvo A, Marklund SL, Andersen PM, Mora G, Chiò A.

Neurobiol Aging. 2018 Dec;72:189.e11-189.e17. doi: 10.1016/j.neurobiolaging.2018.08.014. Epub 2018 Aug 24.

PMID:
30236613
8.

Impact of DNA repair and stability defects on cortical development.

Bianchi FT, Berto GE, Di Cunto F.

Cell Mol Life Sci. 2018 Nov;75(21):3963-3976. doi: 10.1007/s00018-018-2900-2. Epub 2018 Aug 16. Review.

PMID:
30116853
9.

Citron kinase-dependent F-actin maintenance at midbody secondary ingression sites mediates abscission.

Dema A, Macaluso F, Sgrò F, Berto GE, Bianchi FT, Chiotto AA, Pallavicini G, Di Cunto F, Gai M.

J Cell Sci. 2018 Apr 26;131(8). pii: jcs209080. doi: 10.1242/jcs.209080.

10.

IRF4 Mediates the Oncogenic Effects of STAT3 in Anaplastic Large Cell Lymphomas.

Bandini C, Pupuleku A, Spaccarotella E, Pellegrino E, Wang R, Vitale N, Duval C, Cantarella D, Rinaldi A, Provero P, Di Cunto F, Medico E, Bertoni F, Inghirami G, Piva R.

Cancers (Basel). 2018 Jan 18;10(1). pii: E21. doi: 10.3390/cancers10010021.

11.

Of rings and spines: The multiple facets of Citron proteins in neural development.

Bianchi FT, Gai M, Berto GE, Di Cunto F.

Small GTPases. 2017 Nov 29:1-9. doi: 10.1080/21541248.2017.1374325. [Epub ahead of print]

12.

ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules.

Gai M, Bianchi FT, Vagnoni C, Vernì F, Bonaccorsi S, Pasquero S, Berto GE, Sgrò F, Chiotto AA, Annaratone L, Sapino A, Bergo A, Landsberger N, Bond J, Huttner WB, Di Cunto F.

EMBO Rep. 2017 Oct;18(10):1870. doi: 10.15252/embr.201745023. No abstract available.

13.

Citron Kinase Deficiency Leads to Chromosomal Instability and TP53-Sensitive Microcephaly.

Bianchi FT, Tocco C, Pallavicini G, Liu Y, Vernì F, Merigliano C, Bonaccorsi S, El-Assawy N, Priano L, Gai M, Berto GE, Chiotto AM, Sgrò F, Caramello A, Tasca L, Ala U, Neri F, Oliviero S, Mauro A, Geley S, Gatti M, Di Cunto F.

Cell Rep. 2017 Feb 14;18(7):1674-1686. doi: 10.1016/j.celrep.2017.01.054.

14.

ZIKA virus elicits P53 activation and genotoxic stress in human neural progenitors similar to mutations involved in severe forms of genetic microcephaly and p53.

Ghouzzi VE, Bianchi FT, Molineris I, Mounce BC, Berto GE, Rak M, Lebon S, Aubry L, Tocco C, Gai M, Chiotto AM, Sgrò F, Pallavicini G, Simon-Loriere E, Passemard S, Vignuzzi M, Gressens P, Di Cunto F.

Cell Death Dis. 2017 Jan 19;8(1):e2567. doi: 10.1038/cddis.2016.446. No abstract available.

15.

Citron kinase in spindle orientation and primary microcephaly.

Gai M, Di Cunto F.

Cell Cycle. 2017 Feb;16(3):245-246. doi: 10.1080/15384101.2016.1252584. Epub 2016 Nov 10. No abstract available.

16.

ZIKA virus elicits P53 activation and genotoxic stress in human neural progenitors similar to mutations involved in severe forms of genetic microcephaly.

Ghouzzi VE, Bianchi FT, Molineris I, Mounce BC, Berto GE, Rak M, Lebon S, Aubry L, Tocco C, Gai M, Chiotto AM, Sgrò F, Pallavicini G, Simon-Loriere E, Passemard S, Vignuzzi M, Gressens P, Di Cunto F.

Cell Death Dis. 2016 Oct 27;7(10):e2440. doi: 10.1038/cddis.2016.266. Erratum in: Cell Death Dis. 2017 Jan 19;8(1):e2567. Cell Death Dis. 2018 Nov 20;9(12):1155.

17.

ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules.

Gai M, Bianchi FT, Vagnoni C, Vernì F, Bonaccorsi S, Pasquero S, Berto GE, Sgrò F, Chiotto AM, Annaratone L, Sapino A, Bergo A, Landsberger N, Bond J, Huttner WB, Di Cunto F.

EMBO Rep. 2016 Oct;17(10):1396-1409. Epub 2016 Aug 25. Erratum in: EMBO Rep. 2017 Oct;18(10 ):1870.

18.

Mutations in Citron Kinase Cause Recessive Microlissencephaly with Multinucleated Neurons.

Harding BN, Moccia A, Drunat S, Soukarieh O, Tubeuf H, Chitty LS, Verloes A, Gressens P, El Ghouzzi V, Joriot S, Di Cunto F, Martins A, Passemard S, Bielas SL.

Am J Hum Genet. 2016 Aug 4;99(2):511-20. doi: 10.1016/j.ajhg.2016.07.003. Epub 2016 Jul 21.

19.

Tissue-specific control of midbody microtubule stability by Citron kinase through modulation of TUBB3 phosphorylation.

Sgrò F, Bianchi FT, Falcone M, Pallavicini G, Gai M, Chiotto AM, Berto GE, Turco E, Chang YJ, Huttner WB, Di Cunto F.

Cell Death Differ. 2016 May;23(5):801-13. doi: 10.1038/cdd.2015.142. Epub 2015 Nov 20.

20.

Methyl-CpG binding protein 2 (MeCP2) localizes at the centrosome and is required for proper mitotic spindle organization.

Bergo A, Strollo M, Gai M, Barbiero I, Stefanelli G, Sertic S, Cobolli Gigli C, Di Cunto F, Kilstrup-Nielsen C, Landsberger N.

J Biol Chem. 2015 Feb 6;290(6):3223-37. doi: 10.1074/jbc.M114.608125. Epub 2014 Dec 19.

21.

The DCR protein TTC3 affects differentiation and Golgi compactness in neurons through specific actin-regulating pathways.

Berto GE, Iobbi C, Camera P, Scarpa E, Iampietro C, Bianchi F, Gai M, Sgrò F, Cristofani F, Gärtner A, Dotti CG, Di Cunto F.

PLoS One. 2014 Apr 2;9(4):e93721. doi: 10.1371/journal.pone.0093721. eCollection 2014.

22.

p140Cap regulates memory and synaptic plasticity through Src-mediated and citron-N-mediated actin reorganization.

Repetto D, Camera P, Melani R, Morello N, Russo I, Calcagno E, Tomasoni R, Bianchi F, Berto G, Giustetto M, Berardi N, Pizzorusso T, Matteoli M, Di Stefano P, Missler M, Turco E, Di Cunto F, Defilippi P.

J Neurosci. 2014 Jan 22;34(4):1542-53. doi: 10.1523/JNEUROSCI.2341-13.2014.

23.

Drug repositioning for orphan genetic diseases through Conserved Anticoexpressed Gene Clusters (CAGCs).

Molineris I, Ala U, Provero P, Di Cunto F.

BMC Bioinformatics. 2013 Oct 2;14:288. doi: 10.1186/1471-2105-14-288.

24.

Visual search of neuropil-enriched RNAs from brain in situ hybridization data through the image analysis pipeline hippo-ATESC.

Ugolotti R, Mesejo P, Zongaro S, Bardoni B, Berto G, Bianchi F, Molineris I, Giacobini M, Cagnoni S, Di Cunto F.

PLoS One. 2013 Sep 9;8(9):e74481. doi: 10.1371/journal.pone.0074481. eCollection 2013.

25.

The RNA binding protein ESRP1 fine-tunes the expression of pluripotency-related factors in mouse embryonic stem cells.

Fagoonee S, Bearzi C, Di Cunto F, Clohessy JG, Rizzi R, Reschke M, Tolosano E, Provero P, Pandolfi PP, Silengo L, Altruda F.

PLoS One. 2013 Aug 27;8(8):e72300. doi: 10.1371/journal.pone.0072300. eCollection 2013.

26.

HSP27 is required for invasion and metastasis triggered by hepatocyte growth factor.

Pavan S, Musiani D, Torchiaro E, Migliardi G, Gai M, Di Cunto F, Erriquez J, Olivero M, Di Renzo MF.

Int J Cancer. 2014 Mar 15;134(6):1289-99. doi: 10.1002/ijc.28464. Epub 2013 Sep 18.

27.

STAT3-mediated activation of microRNA cluster 17~92 promotes proliferation and survival of ALK-positive anaplastic large cell lymphoma.

Spaccarotella E, Pellegrino E, Ferracin M, Ferreri C, Cuccuru G, Liu C, Iqbal J, Cantarella D, Taulli R, Provero P, Di Cunto F, Medico E, Negrini M, Chan WC, Inghirami G, Piva R.

Haematologica. 2014 Jan;99(1):116-24. doi: 10.3324/haematol.2013.088286. Epub 2013 Aug 23.

28.

A de novo X;8 translocation creates a PTK2-THOC2 gene fusion with THOC2 expression knockdown in a patient with psychomotor retardation and congenital cerebellar hypoplasia.

Di Gregorio E, Bianchi FT, Schiavi A, Chiotto AM, Rolando M, Verdun di Cantogno L, Grosso E, Cavalieri S, Calcia A, Lacerenza D, Zuffardi O, Retta SF, Stevanin G, Marelli C, Durr A, Forlani S, Chelly J, Montarolo F, Tempia F, Beggs HE, Reed R, Squadrone S, Abete MC, Brussino A, Ventura N, Di Cunto F, Brusco A.

J Med Genet. 2013 Aug;50(8):543-51. doi: 10.1136/jmedgenet-2013-101542. Epub 2013 Jun 7.

29.

Disease-gene discovery by integration of 3D gene expression and transcription factor binding affinities.

Piro RM, Molineris I, Di Cunto F, Eils R, König R.

Bioinformatics. 2013 Feb 15;29(4):468-75. doi: 10.1093/bioinformatics/bts720. Epub 2012 Dec 24.

PMID:
23267172
30.

PPP4R2 regulates neuronal cell differentiation and survival, functionally cooperating with SMN.

Bosio Y, Berto G, Camera P, Bianchi F, Ambrogio C, Claus P, Di Cunto F.

Eur J Cell Biol. 2012 Aug;91(8):662-74. doi: 10.1016/j.ejcb.2012.03.002. Epub 2012 May 3.

PMID:
22559936
31.

Shortening of 3'UTRs correlates with poor prognosis in breast and lung cancer.

Lembo A, Di Cunto F, Provero P.

PLoS One. 2012;7(2):e31129. doi: 10.1371/journal.pone.0031129. Epub 2012 Feb 8.

32.

Computational approaches to disease-gene prediction: rationale, classification and successes.

Piro RM, Di Cunto F.

FEBS J. 2012 Mar;279(5):678-96. doi: 10.1111/j.1742-4658.2012.08471.x. Epub 2012 Jan 30. Review.

33.

Additive functions in boolean models of gene regulatory network modules.

Darabos C, Di Cunto F, Tomassini M, Moore JH, Provero P, Giacobini M.

PLoS One. 2011;6(11):e25110. doi: 10.1371/journal.pone.0025110. Epub 2011 Nov 21.

34.

Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs.

Tay Y, Kats L, Salmena L, Weiss D, Tan SM, Ala U, Karreth F, Poliseno L, Provero P, Di Cunto F, Lieberman J, Rigoutsos I, Pandolfi PP.

Cell. 2011 Oct 14;147(2):344-57. doi: 10.1016/j.cell.2011.09.029.

35.

Evaluation of candidate genes from orphan FEB and GEFS+ loci by analysis of human brain gene expression atlases.

Piro RM, Molineris I, Ala U, Di Cunto F.

PLoS One. 2011;6(8):e23149. doi: 10.1371/journal.pone.0023149. Epub 2011 Aug 17.

36.

Citron kinase controls abscission through RhoA and anillin.

Gai M, Camera P, Dema A, Bianchi F, Berto G, Scarpa E, Germena G, Di Cunto F.

Mol Biol Cell. 2011 Oct;22(20):3768-78. doi: 10.1091/mbc.E10-12-0952. Epub 2011 Aug 17.

37.

The collagen chaperone HSP47 is a new interactor of APP that affects the levels of extracellular beta-amyloid peptides.

Bianchi FT, Camera P, Ala U, Imperiale D, Migheli A, Boda E, Tempia F, Berto G, Bosio Y, Oddo S, LaFerla FM, Taraglio S, Dotti CG, Di Cunto F.

PLoS One. 2011;6(7):e22370. doi: 10.1371/journal.pone.0022370. Epub 2011 Jul 28.

38.

An atlas of tissue-specific conserved coexpression for functional annotation and disease gene prediction.

Piro RM, Ala U, Molineris I, Grassi E, Bracco C, Perego GP, Provero P, Di Cunto F.

Eur J Hum Genet. 2011 Nov;19(11):1173-80. doi: 10.1038/ejhg.2011.96. Epub 2011 Jun 8.

39.

A signature inferred from Drosophila mitotic genes predicts survival of breast cancer patients.

Damasco C, Lembo A, Somma MP, Gatti M, Di Cunto F, Provero P.

PLoS One. 2011 Feb 28;6(2):e14737. doi: 10.1371/journal.pone.0014737.

40.

Evolution of promoter affinity for transcription factors in the human lineage.

Molineris I, Grassi E, Ala U, Di Cunto F, Provero P.

Mol Biol Evol. 2011 Aug;28(8):2173-83. doi: 10.1093/molbev/msr027. Epub 2011 Feb 18.

PMID:
21335606
41.

Candidate gene prioritization based on spatially mapped gene expression: an application to XLMR.

Piro RM, Molineris I, Ala U, Provero P, Di Cunto F.

Bioinformatics. 2010 Sep 15;26(18):i618-24. doi: 10.1093/bioinformatics/btq396.

42.

The MeCP2/YY1 interaction regulates ANT1 expression at 4q35: novel hints for Rett syndrome pathogenesis.

Forlani G, Giarda E, Ala U, Di Cunto F, Salani M, Tupler R, Kilstrup-Nielsen C, Landsberger N.

Hum Mol Genet. 2010 Aug 15;19(16):3114-23. doi: 10.1093/hmg/ddq214. Epub 2010 May 26.

43.

A new approach for the identification of processed pseudogenes.

Molineris I, Sales G, Bianchi F, Di Cunto F, Caselle M.

J Comput Biol. 2010 May;17(5):755-65. doi: 10.1089/cmb.2009.0027.

PMID:
20500026
44.

Comparison of 3 Tfr2-deficient murine models suggests distinct functions for Tfr2-alpha and Tfr2-beta isoforms in different tissues.

Roetto A, Di Cunto F, Pellegrino RM, Hirsch E, Azzolino O, Bondi A, Defilippi I, Carturan S, Miniscalco B, Riondato F, Cilloni D, Silengo L, Altruda F, Camaschella C, Saglio G.

Blood. 2010 Apr 22;115(16):3382-9. doi: 10.1182/blood-2009-09-240960. Epub 2010 Feb 23.

45.

Identification of DeltaNp63alpha protein interactions by mass spectrometry.

Amoresano A, Di Costanzo A, Leo G, Di Cunto F, La Mantia G, Guerrini L, Calabrò V.

J Proteome Res. 2010 Apr 5;9(4):2042-8. doi: 10.1021/pr9011156.

PMID:
20085233
46.

The RhoU/Wrch1 Rho GTPase gene is a common transcriptional target of both the gp130/STAT3 and Wnt-1 pathways.

Schiavone D, Dewilde S, Vallania F, Turkson J, Di Cunto F, Poli V.

Biochem J. 2009 Jun 26;421(2):283-92. doi: 10.1042/BJ20090061.

47.

Deletion of the citron kinase gene selectively affects the number and distribution of interneurons in barrelfield cortex.

Muzzi P, Camera P, Di Cunto F, Vercelli A.

J Comp Neurol. 2009 Mar 20;513(3):249-64. doi: 10.1002/cne.21927.

PMID:
19148892
48.

Identification of Drosophila mitotic genes by combining co-expression analysis and RNA interference.

Somma MP, Ceprani F, Bucciarelli E, Naim V, De Arcangelis V, Piergentili R, Palena A, Ciapponi L, Giansanti MG, Pellacani C, Petrucci R, Cenci G, Vernì F, Fasulo B, Goldberg ML, Di Cunto F, Gatti M.

PLoS Genet. 2008 Jul 18;4(7):e1000126. doi: 10.1371/journal.pgen.1000126.

49.

Functional annotation and identification of candidate disease genes by computational analysis of normal tissue gene expression data.

Miozzi L, Piro RM, Rosa F, Ala U, Silengo L, Di Cunto F, Provero P.

PLoS One. 2008 Jun 18;3(6):e2439. doi: 10.1371/journal.pone.0002439.

50.

Prediction of human disease genes by human-mouse conserved coexpression analysis.

Ala U, Piro RM, Grassi E, Damasco C, Silengo L, Oti M, Provero P, Di Cunto F.

PLoS Comput Biol. 2008 Mar 28;4(3):e1000043. doi: 10.1371/journal.pcbi.1000043.

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