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Items: 1 to 50 of 115

1.

Inhibitory protein puts a lid on an epigenetic marker.

Aranda S, Di Croce L.

Nature. 2019 Sep;573(7772):38-39. doi: 10.1038/d41586-019-02521-8. No abstract available.

PMID:
31481771
2.

GATA2 Promotes Hematopoietic Development and Represses Cardiac Differentiation of Human Mesoderm.

Castaño J, Aranda S, Bueno C, Calero-Nieto FJ, Mejia-Ramirez E, Mosquera JL, Blanco E, Wang X, Prieto C, Zabaleta L, Mereu E, Rovira M, Jiménez-Delgado S, Matson DR, Heyn H, Bresnick EH, Göttgens B, Di Croce L, Menendez P, Raya A, Giorgetti A.

Stem Cell Reports. 2019 Sep 10;13(3):515-529. doi: 10.1016/j.stemcr.2019.07.009. Epub 2019 Aug 8.

3.

miR-155 harnesses Phf19 to potentiate cancer immunotherapy through epigenetic reprogramming of CD8+ T cell fate.

Ji Y, Fioravanti J, Zhu W, Wang H, Wu T, Hu J, Lacey NE, Gautam S, Le Gall JB, Yang X, Hocker JD, Escobar TM, He S, Dell'Orso S, Hawk NV, Kapoor V, Telford WG, Di Croce L, Muljo SA, Zhang Y, Sartorelli V, Gattinoni L.

Nat Commun. 2019 May 14;10(1):2157. doi: 10.1038/s41467-019-09882-8.

4.

Chromatin capture links the metabolic enzyme AHCY to stem cell proliferation.

Aranda S, Alcaine-Colet A, Blanco E, Borràs E, Caillot C, Sabidó E, Di Croce L.

Sci Adv. 2019 Mar 6;5(3):eaav2448. doi: 10.1126/sciadv.aav2448. eCollection 2019 Mar.

5.

Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate.

Sardina JL, Collombet S, Tian TV, Gómez A, Di Stefano B, Berenguer C, Brumbaugh J, Stadhouders R, Segura-Morales C, Gut M, Gut IG, Heath S, Aranda S, Di Croce L, Hochedlinger K, Thieffry D, Graf T.

Cell Stem Cell. 2018 Dec 6;23(6):905-906. doi: 10.1016/j.stem.2018.11.001. No abstract available.

6.

Polycomb complexes in normal and malignant hematopoiesis.

Di Carlo V, Mocavini I, Di Croce L.

J Cell Biol. 2019 Jan 7;218(1):55-69. doi: 10.1083/jcb.201808028. Epub 2018 Oct 19. Review.

7.

Promoter bivalency favors an open chromatin architecture in embryonic stem cells.

Mas G, Blanco E, Ballaré C, Sansó M, Spill YG, Hu D, Aoi Y, Le Dily F, Shilatifard A, Marti-Renom MA, Di Croce L.

Nat Genet. 2018 Oct;50(10):1452-1462. doi: 10.1038/s41588-018-0218-5. Epub 2018 Sep 17.

PMID:
30224650
8.

Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate.

Sardina JL, Collombet S, Tian TV, Gómez A, Di Stefano B, Berenguer C, Brumbaugh J, Stadhouders R, Segura-Morales C, Gut M, Gut IG, Heath S, Aranda S, Di Croce L, Hochedlinger K, Thieffry D, Graf T.

Cell Stem Cell. 2018 Nov 1;23(5):727-741.e9. doi: 10.1016/j.stem.2018.08.016. Epub 2018 Sep 13. Erratum in: Cell Stem Cell. 2018 Dec 6;23(6):905-906.

PMID:
30220521
9.

Lamin B1 mapping reveals the existence of dynamic and functional euchromatin lamin B1 domains.

Pascual-Reguant L, Blanco E, Galan S, Le Dily F, Cuartero Y, Serra-Bardenys G, Di Carlo V, Iturbide A, Cebrià-Costa JP, Nonell L, de Herreros AG, Di Croce L, Marti-Renom MA, Peiró S.

Nat Commun. 2018 Aug 24;9(1):3420. doi: 10.1038/s41467-018-05912-z.

10.

A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities.

Conway E, Jerman E, Healy E, Ito S, Holoch D, Oliviero G, Deevy O, Glancy E, Fitzpatrick DJ, Mucha M, Watson A, Rice AM, Chammas P, Huang C, Pratt-Kelly I, Koseki Y, Nakayama M, Ishikura T, Streubel G, Wynne K, Hokamp K, McLysaght A, Ciferri C, Di Croce L, Cagney G, Margueron R, Koseki H, Bracken AP.

Mol Cell. 2018 May 3;70(3):408-421.e8. doi: 10.1016/j.molcel.2018.03.005. Epub 2018 Apr 5.

11.

The Polycomb group protein CBX6 is an essential regulator of embryonic stem cell identity.

Santanach A, Blanco E, Jiang H, Molloy KR, Sansó M, LaCava J, Morey L, Di Croce L.

Nat Commun. 2017 Nov 1;8(1):1235. doi: 10.1038/s41467-017-01464-w.

12.

Genome Regulation by Polycomb and Trithorax: 70 Years and Counting.

Schuettengruber B, Bourbon HM, Di Croce L, Cavalli G.

Cell. 2017 Sep 21;171(1):34-57. doi: 10.1016/j.cell.2017.08.002. Review.

13.

3D structures of individual mammalian genomes studied by single-cell Hi-C.

Stevens TJ, Lando D, Basu S, Atkinson LP, Cao Y, Lee SF, Leeb M, Wohlfahrt KJ, Boucher W, O'Shaughnessy-Kirwan A, Cramard J, Faure AJ, Ralser M, Blanco E, Morey L, Sansó M, Palayret MGS, Lehner B, Di Croce L, Wutz A, Hendrich B, Klenerman D, Laue ED.

Nature. 2017 Apr 6;544(7648):59-64. doi: 10.1038/nature21429. Epub 2017 Mar 13.

14.

Not All H3K4 Methylations Are Created Equal: Mll2/COMPASS Dependency in Primordial Germ Cell Specification.

Hu D, Gao X, Cao K, Morgan MA, Mas G, Smith ER, Volk AG, Bartom ET, Crispino JD, Di Croce L, Shilatifard A.

Mol Cell. 2017 Feb 2;65(3):460-475.e6. doi: 10.1016/j.molcel.2017.01.013.

15.

Targeting metastasis-initiating cells through the fatty acid receptor CD36.

Pascual G, Avgustinova A, Mejetta S, Martín M, Castellanos A, Attolini CS, Berenguer A, Prats N, Toll A, Hueto JA, Bescós C, Di Croce L, Benitah SA.

Nature. 2017 Jan 5;541(7635):41-45. doi: 10.1038/nature20791. Epub 2016 Dec 7.

PMID:
27974793
16.

EPOP Functionally Links Elongin and Polycomb in Pluripotent Stem Cells.

Beringer M, Pisano P, Di Carlo V, Blanco E, Chammas P, Vizán P, Gutiérrez A, Aranda S, Payer B, Wierer M, Di Croce L.

Mol Cell. 2016 Nov 17;64(4):645-658. doi: 10.1016/j.molcel.2016.10.018.

17.

Polycomb-dependent control of cell fate in adult tissue.

Vizán P, Beringer M, Di Croce L.

EMBO J. 2016 Nov 2;35(21):2268-2269. Epub 2016 Oct 4. No abstract available.

18.

Histone demethylase JARID1C inactivation triggers genomic instability in sporadic renal cancer.

Rondinelli B, Rosano D, Antonini E, Frenquelli M, Montanini L, Huang D, Segalla S, Yoshihara K, Amin SB, Lazarevic D, The BT, Verhaak RG, Futreal PA, Di Croce L, Chin L, Cittaro D, Tonon G.

J Clin Invest. 2016 Nov 1;126(11):4387. doi: 10.1172/JCI91191. Epub 2016 Nov 1. No abstract available.

19.

Lysyl oxidase-like 2 (LOXL2) oxidizes trimethylated lysine 4 in histone H3.

Herranz N, Dave N, Millanes-Romero A, Pascual-Reguant L, Morey L, Díaz VM, Lórenz-Fonfría V, Gutierrez-Gallego R, Jerónimo C, Iturbide A, Di Croce L, García de Herreros A, Peiró S.

FEBS J. 2016 Dec;283(23):4263-4273. doi: 10.1111/febs.13922. Epub 2016 Oct 30.

20.

The role of Polycomb in stem cell genome architecture.

Mas G, Di Croce L.

Curr Opin Cell Biol. 2016 Dec;43:87-95. doi: 10.1016/j.ceb.2016.09.006. Epub 2016 Sep 28. Review.

PMID:
27690123
21.

Analysis of Endogenous Protein Interactions of Polycomb Group of Proteins in Mouse Embryonic Stem Cells.

Morey L, Di Croce L.

Methods Mol Biol. 2016;1480:153-65. doi: 10.1007/978-1-4939-6380-5_14.

PMID:
27659983
22.

Dnmt3a and Dnmt3b Associate with Enhancers to Regulate Human Epidermal Stem Cell Homeostasis.

Rinaldi L, Datta D, Serrat J, Morey L, Solanas G, Avgustinova A, Blanco E, Pons JI, Matallanas D, Von Kriegsheim A, Di Croce L, Benitah SA.

Cell Stem Cell. 2016 Oct 6;19(4):491-501. doi: 10.1016/j.stem.2016.06.020. Epub 2016 Jul 28.

23.

Chromatin and Epigenetics at the Forefront: Finding Clues among Peaks.

Aranda S, Shi Y, Di Croce L.

Mol Cell Biol. 2016 Sep 12;36(19):2432-9. doi: 10.1128/MCB.00328-16. Print 2016 Oct 1. Review.

24.

Retraction Notice to: Lysyl Oxidase-like 2 Deaminates Lysine 4 in Histone H3.

Herranz N, Dave N, Millanes-Romero A, Morey L, Díaz VM, Lórenz-Fonfría V, Gutierrez-Gallego R, Jerónimo C, Di Croce L, García de Herreros A, Peiró S.

Mol Cell. 2016 Jul 7;63(1):180. doi: 10.1016/j.molcel.2016.06.013. No abstract available.

25.

The dynamic interactome and genomic targets of Polycomb complexes during stem-cell differentiation.

Kloet SL, Makowski MM, Baymaz HI, van Voorthuijsen L, Karemaker ID, Santanach A, Jansen PWTC, Di Croce L, Vermeulen M.

Nat Struct Mol Biol. 2016 Jul;23(7):682-690. doi: 10.1038/nsmb.3248. Epub 2016 Jun 13.

26.

PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3.

Chung HR, Xu C, Fuchs A, Mund A, Lange M, Staege H, Schubert T, Bian C, Dunkel I, Eberharter A, Regnard C, Klinker H, Meierhofer D, Cozzuto L, Winterpacht A, Di Croce L, Min J, Will H, Kinkley S.

Elife. 2016 May 25;5. pii: e10607. doi: 10.7554/eLife.10607.

27.

Editorial overview: Cancer genomics: Darwin meets Waddington: the interplay between cancer genomes and epigenomes.

Di Croce L, Shilatifard A.

Curr Opin Genet Dev. 2016 Feb;36:iv-vi. doi: 10.1016/j.gde.2016.04.007. Epub 2016 May 6. No abstract available.

PMID:
27160922
28.

Emerging roles for Polycomb proteins in cancer.

Pasini D, Di Croce L.

Curr Opin Genet Dev. 2016 Feb;36:50-8. doi: 10.1016/j.gde.2016.03.013. Epub 2016 May 2. Review.

PMID:
27151431
29.

The Dynamic Regulatory Genome of Capsaspora and the Origin of Animal Multicellularity.

Sebé-Pedrós A, Ballaré C, Parra-Acero H, Chiva C, Tena JJ, Sabidó E, Gómez-Skarmeta JL, Di Croce L, Ruiz-Trillo I.

Cell. 2016 May 19;165(5):1224-1237. doi: 10.1016/j.cell.2016.03.034. Epub 2016 Apr 21.

30.

Mutations and deletions of PRC2 in prostate cancer.

Jain P, Di Croce L.

Bioessays. 2016 May;38(5):446-54. doi: 10.1002/bies.201500162. Epub 2016 Mar 22. Review.

PMID:
27000413
31.

Barcelona conference on epigenetics and cancer 2015: Coding and non-coding functions of the genome.

Corujo D, Mas G, Malinverni R, Di Croce L, Buschbeck M.

Epigenetics. 2016;11(1):95-100. doi: 10.1080/15592294.2015.1131377.

32.

Chromatin and RNA Maps Reveal Regulatory Long Noncoding RNAs in Mouse.

Bogu GK, Vizán P, Stanton LW, Beato M, Di Croce L, Marti-Renom MA.

Mol Cell Biol. 2015 Dec 28;36(5):809-19. doi: 10.1128/MCB.00955-15.

33.

Regulation of gene transcription by Polycomb proteins.

Aranda S, Mas G, Di Croce L.

Sci Adv. 2015 Dec 4;1(11):e1500737. doi: 10.1126/sciadv.1500737. eCollection 2015 Dec.

34.

Histone demethylase JARID1C inactivation triggers genomic instability in sporadic renal cancer.

Rondinelli B, Rosano D, Antonini E, Frenquelli M, Montanini L, Huang D, Segalla S, Yoshihara K, Amin SB, Lazarevic D, The BT, Verhaak RG, Futreal PA, Di Croce L, Chin L, Cittaro D, Tonon G.

J Clin Invest. 2015 Dec;125(12):4625-37. doi: 10.1172/JCI81040. Epub 2015 Nov 9. Erratum in: J Clin Invest. 2016 Nov 1;126(11):4387.

35.

p53 regulates the mevalonate pathway in human glioblastoma multiforme.

Laezza C, D'Alessandro A, Di Croce L, Picardi P, Ciaglia E, Pisanti S, Malfitano AM, Comegna M, Faraonio R, Gazzerro P, Bifulco M.

Cell Death Dis. 2015 Oct 15;6:e1909. doi: 10.1038/cddis.2015.279.

36.

Polycomb Regulates Mesoderm Cell Fate-Specification in Embryonic Stem Cells through Activation and Repression Mechanisms.

Morey L, Santanach A, Blanco E, Aloia L, Nora EP, Bruneau BG, Di Croce L.

Cell Stem Cell. 2015 Sep 3;17(3):300-15. doi: 10.1016/j.stem.2015.08.009.

37.

Pluripotency and Epigenetic Factors in Mouse Embryonic Stem Cell Fate Regulation.

Morey L, Santanach A, Di Croce L.

Mol Cell Biol. 2015 Aug;35(16):2716-28. doi: 10.1128/MCB.00266-15. Epub 2015 Jun 1. Review.

38.

Special issue: epigenetics: introduction.

Muñoz-Cánoves P, Di Croce L.

FEBS J. 2015 May;282(9):1569-70. doi: 10.1111/febs.13281. Epub 2015 Apr 20.

39.

ZRF1: a novel epigenetic regulator of stem cell identity and cancer.

Aloia L, Demajo S, Di Croce L.

Cell Cycle. 2015;14(4):510-5. doi: 10.4161/15384101.2014.988022. Review.

40.

Transcriptional regulation of Sox2 by the retinoblastoma family of pocket proteins.

Vilas JM, Ferreirós A, Carneiro C, Morey L, Da Silva-Álvarez S, Fernandes T, Abad M, Di Croce L, García-Caballero T, Serrano M, Rivas C, Vidal A, Collado M.

Oncotarget. 2015 Feb 20;6(5):2992-3002.

41.

Direct interaction between Id1 and Zrf1 controls neural differentiation of embryonic stem cells.

Aloia L, Gutierrez A, Caballero JM, Di Croce L.

EMBO Rep. 2015 Jan;16(1):63-70. doi: 10.15252/embr.201439560. Epub 2014 Oct 31.

42.

Role of PRC2-associated factors in stem cells and disease.

Vizán P, Beringer M, Ballaré C, Di Croce L.

FEBS J. 2015 May;282(9):1723-35. doi: 10.1111/febs.13083. Epub 2014 Oct 25. Review.

43.

Role of UTX in retinoic acid receptor-mediated gene regulation in leukemia.

Rocha-Viegas L, Villa R, Gutierrez A, Iriondo O, Shiekhattar R, Di Croce L.

Mol Cell Biol. 2014 Oct 1;34(19):3765-75. doi: 10.1128/MCB.00839-14. Epub 2014 Jul 28.

44.

VAV3 mediates resistance to breast cancer endocrine therapy.

Aguilar H, Urruticoechea A, Halonen P, Kiyotani K, Mushiroda T, Barril X, Serra-Musach J, Islam A, Caizzi L, Di Croce L, Nevedomskaya E, Zwart W, Bostner J, Karlsson E, Pérez Tenorio G, Fornander T, Sgroi DC, Garcia-Mata R, Jansen MP, García N, Bonifaci N, Climent F, Soler MT, Rodríguez-Vida A, Gil M, Brunet J, Martrat G, Gómez-Baldó L, Extremera AI, Figueras A, Balart J, Clarke R, Burnstein KL, Carlson KE, Katzenellenbogen JA, Vizoso M, Esteller M, Villanueva A, Rodríguez-Peña AB, Bustelo XR, Nakamura Y, Zembutsu H, Stål O, Beijersbergen RL, Pujana MA.

Breast Cancer Res. 2014 May 28;16(3):R53. doi: 10.1186/bcr3664.

45.

Genome-wide activity of unliganded estrogen receptor-α in breast cancer cells.

Caizzi L, Ferrero G, Cutrupi S, Cordero F, Ballaré C, Miano V, Reineri S, Ricci L, Friard O, Testori A, Corà D, Caselle M, Di Croce L, De Bortoli M.

Proc Natl Acad Sci U S A. 2014 Apr 1;111(13):4892-7. doi: 10.1073/pnas.1315445111. Epub 2014 Mar 17.

46.

Zrf1 is required to establish and maintain neural progenitor identity.

Aloia L, Di Stefano B, Sessa A, Morey L, Santanach A, Gutierrez A, Cozzuto L, Benitah SA, Graf T, Broccoli V, Di Croce L.

Genes Dev. 2014 Jan 15;28(2):182-97. doi: 10.1101/gad.228510.113.

47.

ZRF1 controls the retinoic acid pathway and regulates leukemogenic potential in acute myeloid leukemia.

Demajo S, Uribesalgo I, Gutiérrez A, Ballaré C, Capdevila S, Roth M, Zuber J, Martín-Caballero J, Di Croce L.

Oncogene. 2014 Nov 27;33(48):5501-10. doi: 10.1038/onc.2013.501. Epub 2013 Dec 2.

PMID:
24292673
48.

Landscape of somatic mutations and clonal evolution in mantle cell lymphoma.

Beà S, Valdés-Mas R, Navarro A, Salaverria I, Martín-Garcia D, Jares P, Giné E, Pinyol M, Royo C, Nadeu F, Conde L, Juan M, Clot G, Vizán P, Di Croce L, Puente DA, López-Guerra M, Moros A, Roue G, Aymerich M, Villamor N, Colomo L, Martínez A, Valera A, Martín-Subero JI, Amador V, Hernández L, Rozman M, Enjuanes A, Forcada P, Muntañola A, Hartmann EM, Calasanz MJ, Rosenwald A, Ott G, Hernández-Rivas JM, Klapper W, Siebert R, Wiestner A, Wilson WH, Colomer D, López-Guillermo A, López-Otín C, Puente XS, Campo E.

Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18250-5. doi: 10.1073/pnas.1314608110. Epub 2013 Oct 21.

49.

Transcriptional regulation by Polycomb group proteins.

Di Croce L, Helin K.

Nat Struct Mol Biol. 2013 Oct;20(10):1147-55. doi: 10.1038/nsmb.2669. Review.

PMID:
24096405
50.

p16INK4a in cellular senescence.

Simboeck E, Di Croce L.

Aging (Albany NY). 2013 Aug;5(8):590-1. No abstract available.

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