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Items: 35


Toxoplasma Cathepsin Protease B and Aspartyl Protease 1 Are Dispensable for Endolysosomal Protein Digestion.

McDonald C, Smith D, Di Cristina M, Kannan G, Dou Z, Carruthers VB.

mSphere. 2020 Feb 12;5(1). pii: e00869-19. doi: 10.1128/mSphere.00869-19.


Toxoplasma gondii: Bradyzoite Differentiation In Vitro and In Vivo.

Mayoral J, Di Cristina M, Carruthers VB, Weiss LM.

Methods Mol Biol. 2020;2071:269-282. doi: 10.1007/978-1-4939-9857-9_15.


PCR Screening of Toxoplasma gondii Single Clones Directly from 96-Well Plates Without DNA Purification.

Piro F, Carruthers VB, Di Cristina M.

Methods Mol Biol. 2020;2071:117-123. doi: 10.1007/978-1-4939-9857-9_6.


Role of Toxoplasma gondii Chloroquine Resistance Transporter in Bradyzoite Viability and Digestive Vacuole Maintenance.

Kannan G, Di Cristina M, Schultz AJ, Huynh MH, Wang F, Schultz TL, Lunghi M, Coppens I, Carruthers VB.

mBio. 2019 Aug 6;10(4). pii: e01324-19. doi: 10.1128/mBio.01324-19.


An ortholog of Plasmodium falciparum chloroquine resistance transporter (PfCRT) plays a key role in maintaining the integrity of the endolysosomal system in Toxoplasma gondii to facilitate host invasion.

Thornton LB, Teehan P, Floyd K, Cochrane C, Bergmann A, Riegel B, Stasic AJ, Di Cristina M, Moreno SNJ, Roepe PD, Dou Z.

PLoS Pathog. 2019 Jun 6;15(6):e1007775. doi: 10.1371/journal.ppat.1007775. eCollection 2019 Jun.


New and emerging uses of CRISPR/Cas9 to genetically manipulate apicomplexan parasites.

Di Cristina M, Carruthers VB.

Parasitology. 2018 Aug;145(9):1119-1126. doi: 10.1017/S003118201800001X. Epub 2018 Feb 21. Review.


Toxoplasma-induced changes in host risk behaviour are independent of parasite-derived AaaH2 tyrosine hydroxylase.

Afonso C, Paixão VB, Klaus A, Lunghi M, Piro F, Emiliani C, Di Cristina M, Costa RM.

Sci Rep. 2017 Oct 23;7(1):13822. doi: 10.1038/s41598-017-13229-y.


Toxoplasma depends on lysosomal consumption of autophagosomes for persistent infection.

Di Cristina M, Dou Z, Lunghi M, Kannan G, Huynh MH, McGovern OL, Schultz TL, Schultz AJ, Miller AJ, Hayes BM, van der Linden W, Emiliani C, Bogyo M, Besteiro S, Coppens I, Carruthers VB.

Nat Microbiol. 2017 Jun 19;2:17096. doi: 10.1038/nmicrobiol.2017.96.


Fundamental Roles of the Golgi-Associated Toxoplasma Aspartyl Protease, ASP5, at the Host-Parasite Interface.

Hammoudi PM, Jacot D, Mueller C, Di Cristina M, Dogga SK, Marq JB, Romano J, Tosetti N, Dubrot J, Emre Y, Lunghi M, Coppens I, Yamamoto M, Sojka D, Pino P, Soldati-Favre D.

PLoS Pathog. 2015 Oct 16;11(10):e1005211. doi: 10.1371/journal.ppat.1005211. eCollection 2015 Oct.


Alternative splicing mechanisms orchestrating post-transcriptional gene expression: intron retention and the intron-rich genome of apicomplexan parasites.

Lunghi M, Spano F, Magini A, Emiliani C, Carruthers VB, Di Cristina M.

Curr Genet. 2016 Feb;62(1):31-8. doi: 10.1007/s00294-015-0506-x. Epub 2015 Jul 21.


Expression of the glycolytic enzymes enolase and lactate dehydrogenase during the early phase of Toxoplasma differentiation is regulated by an intron retention mechanism.

Lunghi M, Galizi R, Magini A, Carruthers VB, Di Cristina M.

Mol Microbiol. 2015 Jun;96(6):1159-75. doi: 10.1111/mmi.12999. Epub 2015 Apr 11.


The germline of the malaria mosquito produces abundant miRNAs, endo-siRNAs, piRNAs and 29-nt small RNAs.

Castellano L, Rizzi E, Krell J, Di Cristina M, Galizi R, Mori A, Tam J, De Bellis G, Stebbing J, Crisanti A, Nolan T.

BMC Genomics. 2015 Feb 19;16:100. doi: 10.1186/s12864-015-1257-2.


Toxoplasma gondii ingests and digests host cytosolic proteins.

Dou Z, McGovern OL, Di Cristina M, Carruthers VB.

mBio. 2014 Jul 15;5(4):e01188-14. doi: 10.1128/mBio.01188-14.


Methods to discriminate the distribution of acidic glycohydrolases between the endosomal-lysosomal systems and the plasma membrane.

Magini A, Polchi A, Tancini B, Urbanelli L, Di Cristina M, Mannucci R, Nicoletti I, Emiliani C.

Methods Enzymol. 2014;534:25-45. doi: 10.1016/B978-0-12-397926-1.00002-0.


Evidence of tRNA cleavage in apicomplexan parasites: Half-tRNAs as new potential regulatory molecules of Toxoplasma gondii and Plasmodium berghei.

Galizi R, Spano F, Giubilei MA, Capuccini B, Magini A, Urbanelli L, Ogawa T, Dubey JP, Spaccapelo R, Emiliani C, Di Cristina M.

Mol Biochem Parasitol. 2013 Apr;188(2):99-108. doi: 10.1016/j.molbiopara.2013.03.003. Epub 2013 Apr 1.


Disruption of plasmepsin-4 and merozoites surface protein-7 genes in Plasmodium berghei induces combined virulence-attenuated phenotype.

Spaccapelo R, Aime E, Caterbi S, Arcidiacono P, Capuccini B, Di Cristina M, Dottorini T, Rende M, Bistoni F, Crisanti A.

Sci Rep. 2011;1:39. doi: 10.1038/srep00039. Epub 2011 Jul 18.


An antigen microarray immunoassay for multiplex screening of mouse monoclonal antibodies.

Di Cristina M, Nunziangeli L, Giubilei MA, Capuccini B, d'Episcopo L, Mazzoleni G, Baldracchini F, Spaccapelo R, Crisanti A.

Nat Protoc. 2010 Dec;5(12):1932-44. doi: 10.1038/nprot.2010.161. Epub 2010 Nov 10.


Plasmepsin 4-deficient Plasmodium berghei are virulence attenuated and induce protective immunity against experimental malaria.

Spaccapelo R, Janse CJ, Caterbi S, Franke-Fayard B, Bonilla JA, Syphard LM, Di Cristina M, Dottorini T, Savarino A, Cassone A, Bistoni F, Waters AP, Dame JB, Crisanti A.

Am J Pathol. 2010 Jan;176(1):205-17. doi: 10.2353/ajpath.2010.090504. Epub 2009 Dec 17.


Temporal and spatial distribution of Toxoplasma gondii differentiation into Bradyzoites and tissue cyst formation in vivo.

Di Cristina M, Marocco D, Galizi R, Proietti C, Spaccapelo R, Crisanti A.

Infect Immun. 2008 Aug;76(8):3491-501. doi: 10.1128/IAI.00254-08. Epub 2008 May 27.


A novel approach for identification of tumor-associated antigens expressed on the surface of tumor cells.

Di Cristina M, Minenkova O, Pavoni E, Beghetto E, Spadoni A, Felici F, Gargano N.

Int J Cancer. 2007 Mar 15;120(6):1293-303.


Toxoplasma gondii: DNA vaccination with bradyzoite antigens induces protective immunity in mice against oral infection with parasite cysts.

Nielsen HV, Di Cristina M, Beghetto E, Spadoni A, Petersen E, Gargano N.

Exp Parasitol. 2006 Apr;112(4):274-9. Epub 2005 Dec 20.


Use of recombinant antigens for early postnatal diagnosis of congenital toxoplasmosis.

Buffolano W, Beghetto E, Del Pezzo M, Spadoni A, Di Cristina M, Petersen E, Gargano N.

J Clin Microbiol. 2005 Dec;43(12):5916-24.


The Toxoplasma gondii bradyzoite antigens BAG1 and MAG1 induce early humoral and cell-mediated immune responses upon human infection.

Di Cristina M, Del Porto P, Buffolano W, Beghetto E, Spadoni A, Guglietta S, Piccolella E, Felici F, Gargano N.

Microbes Infect. 2004 Feb;6(2):164-71.


Use of an immunoglobulin G avidity assay based on recombinant antigens for diagnosis of primary Toxoplasma gondii infection during pregnancy.

Beghetto E, Buffolano W, Spadoni A, Del Pezzo M, Di Cristina M, Minenkova O, Petersen E, Felici F, Gargano N.

J Clin Microbiol. 2003 Dec;41(12):5414-8.


Intramembrane cleavage of microneme proteins at the surface of the apicomplexan parasite Toxoplasma gondii.

Opitz C, Di Cristina M, Reiss M, Ruppert T, Crisanti A, Soldati D.

EMBO J. 2002 Apr 2;21(7):1577-85.


The SAG5 locus of Toxoplasma gondii encodes three novel proteins belonging to the SAG1 family of surface antigens.

Spano F, Ricci I, Di Cristina M, Possenti A, Tinti M, Dendouga N, Tomavo S, Crisanti A.

Int J Parasitol. 2002 Feb;32(2):121-31.


Antigen microarrays for serodiagnosis of infectious diseases.

Mezzasoma L, Bacarese-Hamilton T, Di Cristina M, Rossi R, Bistoni F, Crisanti A.

Clin Chem. 2002 Jan;48(1):121-30.


Identification and characterization of an escorter for two secretory adhesins in Toxoplasma gondii.

Reiss M, Viebig N, Brecht S, Fourmaux MN, Soete M, Di Cristina M, Dubremetz JF, Soldati D.

J Cell Biol. 2001 Feb 5;152(3):563-78.


Two conserved amino acid motifs mediate protein targeting to the micronemes of the apicomplexan parasite Toxoplasma gondii.

Di Cristina M, Spaccapelo R, Soldati D, Bistoni F, Crisanti A.

Mol Cell Biol. 2000 Oct;20(19):7332-41.


Promoter sequences of the putative Anopheles gambiae apyrase confer salivary gland expression in Drosophila melanogaster.

Lombardo F, Di Cristina M, Spanos L, Louis C, Coluzzi M, Arcá B.

J Biol Chem. 2000 Aug 4;275(31):23861-8.


Transformed Toxoplasma gondii tachyzoites expressing the circumsporozoite protein of Plasmodium knowlesi elicit a specific immune response in rhesus monkeys.

Di Cristina M, Ghouze F, Kocken CH, Naitza S, Cellini P, Soldati D, Thomas AW, Crisanti A.

Infect Immun. 1999 Apr;67(4):1677-82.


The Arabidopsis Athb-10 (GLABRA2) is an HD-Zip protein required for regulation of root hair development.

Di Cristina M, Sessa G, Dolan L, Linstead P, Baima S, Ruberti I, Morelli G.

Plant J. 1996 Sep;10(3):393-402.


Xenopus laevis ribosomal protein S1a cDNA sequence.

Di Cristina M, Menard R, Pierandrei-Amaldi P.

Nucleic Acids Res. 1991 Apr 25;19(8):1943. No abstract available.


[Research on power lysozyme in blood serum in normal conditions and in some infectious diseases of childhood].


Pediatria (Rio). 1949 Jan-Feb;57(1-2):41-8. Italian. No abstract available.


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