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Items: 1 to 20 of 41


Chloride transporters and channels in β-cell physiology: revisiting a 40-year-old model.

Di Fulvio M, Aguilar-Bryan L.

Biochem Soc Trans. 2019 Nov 7. pii: BST20190513. doi: 10.1042/BST20190513. [Epub ahead of print]


Impaired glucose tolerance, glucagon, and insulin responses in mice lacking the loop diuretic-sensitive Nkcc2a transporter.

Kelly L, Almutairi MM, Kursan S, Pacheco R, Dias-Junior E, Castrop H, Di Fulvio M.

Am J Physiol Cell Physiol. 2019 Oct 1;317(4):C843-C856. doi: 10.1152/ajpcell.00144.2019. Epub 2019 Jul 31.


The neuronal K+Cl- co-transporter 2 (Slc12a5) modulates insulin secretion.

Kursan S, McMillen TS, Beesetty P, Dias-Junior E, Almutairi MM, Sajib AA, Kozak JA, Aguilar-Bryan L, Di Fulvio M.

Sci Rep. 2017 May 11;7(1):1732. doi: 10.1038/s41598-017-01814-0.


Survival and growth of C57BL/6J mice lacking the BK channel, Kcnma1: lower adult body weight occurs together with higher body fat.

Halm ST, Bottomley MA, Almutairi MM, Di Fulvio M, Halm DR.

Physiol Rep. 2017 Feb;5(4). pii: e13137. doi: 10.14814/phy2.13137. Epub 2017 Feb 27.


Plasma Membrane Targeting of Endogenous NKCC2 in COS7 Cells Bypasses Functional Golgi Cisternae and Complex N-Glycosylation.

Singh R, Kursan S, Almiahoub MY, Almutairi MM, Garzón-Muvdi T, Alvarez-Leefmans FJ, Di Fulvio M.

Front Cell Dev Biol. 2017 Jan 4;4:150. doi: 10.3389/fcell.2016.00150. eCollection 2016.


A highly efficient strategy to determine genotypes of genetically-engineered mice using genomic DNA purified from hair roots.

Otaño-Rivera V, Boakye A, Grobe N, Almutairi MM, Kursan S, Mattis LK, Castrop H, Gurley SB, Elased KM, Boivin GP, Di Fulvio M.

Lab Anim. 2017 Apr;51(2):138-146. doi: 10.1177/0023677216646088. Epub 2016 Jul 10.


Increased Slc12a1 expression in β-cells and improved glucose disposal in Slc12a2 heterozygous mice.

Alshahrani S, Almutairi MM, Kursan S, Dias-Junior E, Almiahuob MM, Aguilar-Bryan L, Di Fulvio M.

J Endocrinol. 2015 Dec;227(3):153-65. doi: 10.1530/JOE-15-0327. Epub 2015 Sep 23.


Impact of Hybrid and Complex N-Glycans on Cell Surface Targeting of the Endogenous Chloride Cotransporter Slc12a2.

Singh R, Almutairi MM, Pacheco-Andrade R, Almiahuob MY, Di Fulvio M.

Int J Cell Biol. 2015;2015:505294. doi: 10.1155/2015/505294. Epub 2015 Aug 17.


Functional and molecular evidence for expression of the renin angiotensin system and ADAM17-mediated ACE2 shedding in COS7 cells.

Grobe N, Di Fulvio M, Kashkari N, Chodavarapu H, Somineni HK, Singh R, Elased KM.

Am J Physiol Cell Physiol. 2015 May 1;308(9):C767-77. doi: 10.1152/ajpcell.00247.2014. Epub 2015 Mar 4.


A molecular analysis of the Na(+)-independent cation chloride cotransporters.

Gagnon KB, Di Fulvio M.

Cell Physiol Biochem. 2013;32(7):14-31. doi: 10.1159/000356621. Epub 2013 Dec 18. Review.


Enhanced insulin secretion and improved glucose tolerance in mice with homozygous inactivation of the Na(+)K(+)2Cl(-) co-transporter 1.

Alshahrani S, Di Fulvio M.

J Endocrinol. 2012 Oct;215(1):59-70. doi: 10.1530/JOE-12-0244. Epub 2012 Aug 7.


Expression of the Slc12a1 gene in pancreatic β-cells: molecular characterization and in silico analysis.

Alshahrani S, Alvarez-Leefmans FJ, Di Fulvio M.

Cell Physiol Biochem. 2012;30(1):95-112. doi: 10.1159/000339050. Epub 2012 Jun 12. Erratum in: Cell Physiol Biochem. 2013;31(2-3):486. Alvarez-Leefmans, Francisco J [added].


Molecular and functional expression of cation-chloride cotransporters in dorsal root ganglion neurons during postnatal maturation.

Mao S, Garzon-Muvdi T, Di Fulvio M, Chen Y, Delpire E, Alvarez FJ, Alvarez-Leefmans FJ.

J Neurophysiol. 2012 Aug 1;108(3):834-52. doi: 10.1152/jn.00970.2011. Epub 2012 Mar 28.


KCC2a expression in a human fetal lens epithelial cell line.

Lauf PK, Di Fulvio M, Srivastava V, Sharma N, Adragna NC.

Cell Physiol Biochem. 2012;29(1-2):303-12. doi: 10.1159/000337611. Epub 2012 Mar 1.


Phospholipase D2 (PLD2) shortens the time required for myeloid leukemic cell differentiation: mechanism of action.

Di Fulvio M, Frondorf K, Henkels KM, Grunwald WC Jr, Cool D, Gomez-Cambronero J.

J Biol Chem. 2012 Jan 2;287(1):393-407. doi: 10.1074/jbc.M111.259465. Epub 2011 Nov 17.


Mammalian target of rapamycin (mTOR) and S6 kinase down-regulate phospholipase D2 basal expression and function.

Tabatabaian F, Dougherty K, Di Fulvio M, Gomez-Cambronero J.

J Biol Chem. 2010 Jun 18;285(25):18991-9001. doi: 10.1074/jbc.M110.111542. Epub 2010 Apr 21.


PLD2 has both enzymatic and cell proliferation-inducing capabilities, that are differentially regulated by phosphorylation and dephosphorylation.

Henkels KM, Short S, Peng HJ, Di Fulvio M, Gomez-Cambronero J.

Biochem Biophys Res Commun. 2009 Nov 13;389(2):224-8. doi: 10.1016/j.bbrc.2009.08.109. Epub 2009 Aug 26.


Tyrosine phosphorylation of Grb2: role in prolactin/epidermal growth factor cross talk in mammary epithelial cell growth and differentiation.

Haines E, Minoo P, Feng Z, Resalatpanah N, Nie XM, Campiglio M, Alvarez L, Cocolakis E, Ridha M, Di Fulvio M, Gomez-Cambronero J, Lebrun JJ, Ali S.

Mol Cell Biol. 2009 May;29(10):2505-20. doi: 10.1128/MCB.00034-09. Epub 2009 Mar 9.


Mutation of Y179 on phospholipase D2 (PLD2) upregulates DNA synthesis in a PI3K-and Akt-dependent manner.

Di Fulvio M, Frondorf K, Gomez-Cambronero J.

Cell Signal. 2008 Jan;20(1):176-85. Epub 2007 Oct 13.


Short-hairpin RNA-mediated stable silencing of Grb2 impairs cell growth and DNA synthesis.

Di Fulvio M, Henkels KM, Gomez-Cambronero J.

Biochem Biophys Res Commun. 2007 Jun 8;357(3):737-42. Epub 2007 Apr 10.

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