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Items: 15

1.

Homeostasis and transitional activation of regulatory T cells require c-Myc.

Saravia J, Zeng H, Dhungana Y, Bastardo Blanco D, Nguyen TM, Chapman NM, Wang Y, Kanneganti A, Liu S, Raynor JL, Vogel P, Neale G, Carmeliet P, Chi H.

Sci Adv. 2020 Jan 1;6(1):eaaw6443. doi: 10.1126/sciadv.aaw6443. eCollection 2020 Jan.

2.

Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy.

Wei J, Long L, Zheng W, Dhungana Y, Lim SA, Guy C, Wang Y, Wang YD, Qian C, Xu B, Kc A, Saravia J, Huang H, Yu J, Doench JG, Geiger TL, Chi H.

Nature. 2019 Dec;576(7787):471-476. doi: 10.1038/s41586-019-1821-z. Epub 2019 Dec 11.

PMID:
31827283
3.

Mevalonate metabolism-dependent protein geranylgeranylation regulates thymocyte egress.

Du X, Zeng H, Liu S, Guy C, Dhungana Y, Neale G, Bergo MO, Chi H.

J Exp Med. 2020 Feb 3;217(2). pii: e20190969. doi: 10.1084/jem.20190969.

PMID:
31722972
4.

Amino Acids License Kinase mTORC1 Activity and Treg Cell Function via Small G Proteins Rag and Rheb.

Shi H, Chapman NM, Wen J, Guy C, Long L, Dhungana Y, Rankin S, Pelletier S, Vogel P, Wang H, Peng J, Guan KL, Chi H.

Immunity. 2019 Dec 17;51(6):1012-1027.e7. doi: 10.1016/j.immuni.2019.10.001. Epub 2019 Oct 24.

PMID:
31668641
5.

LKB1 orchestrates dendritic cell metabolic quiescence and anti-tumor immunity.

Wang Y, Du X, Wei J, Long L, Tan H, Guy C, Dhungana Y, Qian C, Neale G, Fu YX, Yu J, Peng J, Chi H.

Cell Res. 2019 May;29(5):391-405. doi: 10.1038/s41422-019-0157-4. Epub 2019 Mar 25.

PMID:
30911060
6.

Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity.

Karmaus PWF, Chen X, Lim SA, Herrada AA, Nguyen TM, Xu B, Dhungana Y, Rankin S, Chen W, Rosencrance C, Yang K, Fan Y, Cheng Y, Easton J, Neale G, Vogel P, Chi H.

Nature. 2019 Jan;565(7737):101-105. doi: 10.1038/s41586-018-0806-7. Epub 2018 Dec 19.

7.

Hippo Kinases Mst1 and Mst2 Sense and Amplify IL-2R-STAT5 Signaling in Regulatory T Cells to Establish Stable Regulatory Activity.

Shi H, Liu C, Tan H, Li Y, Nguyen TM, Dhungana Y, Guy C, Vogel P, Neale G, Rankin S, Feng Y, Peng J, Tao W, Chi H.

Immunity. 2018 Nov 20;49(5):899-914.e6. doi: 10.1016/j.immuni.2018.10.010. Epub 2018 Nov 6.

8.

Metabolic signaling directs the reciprocal lineage decisions of αβ and γδ T cells.

Yang K, Blanco DB, Chen X, Dash P, Neale G, Rosencrance C, Easton J, Chen W, Cheng C, Dhungana Y, Kc A, Awad W, Guo XJ, Thomas PG, Chi H.

Sci Immunol. 2018 Jul 6;3(25). pii: eaas9818. doi: 10.1126/sciimmunol.aas9818.

9.

Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells.

Du X, Wen J, Wang Y, Karmaus PWF, Khatamian A, Tan H, Li Y, Guy C, Nguyen TM, Dhungana Y, Neale G, Peng J, Yu J, Chi H.

Nature. 2018 Jun;558(7708):141-145. doi: 10.1038/s41586-018-0177-0. Epub 2018 May 30.

10.

mTOR coordinates transcriptional programs and mitochondrial metabolism of activated Treg subsets to protect tissue homeostasis.

Chapman NM, Zeng H, Nguyen TM, Wang Y, Vogel P, Dhungana Y, Liu X, Neale G, Locasale JW, Chi H.

Nat Commun. 2018 May 29;9(1):2095. doi: 10.1038/s41467-018-04392-5.

11.

Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis.

Zeng H, Yu M, Tan H, Li Y, Su W, Shi H, Dhungana Y, Guy C, Neale G, Cloer C, Peng J, Wang D, Chi H.

Sci Adv. 2018 Jan 31;4(1):eaar5701. doi: 10.1126/sciadv.aar5701. eCollection 2018 Jan.

12.

Critical roles of mTORC1 signaling and metabolic reprogramming for M-CSF-mediated myelopoiesis.

Karmaus PWF, Herrada AA, Guy C, Neale G, Dhungana Y, Long L, Vogel P, Avila J, Clish CB, Chi H.

J Exp Med. 2017 Sep 4;214(9):2629-2647. doi: 10.1084/jem.20161855. Epub 2017 Aug 7.

13.

Truncated HSPB1 causes axonal neuropathy and impairs tolerance to unfolded protein stress.

Ylikallio E, Konovalova S, Dhungana Y, Hilander T, Junna N, Partanen JV, Toppila JP, Auranen M, Tyynismaa H.

BBA Clin. 2015 Mar 11;3:233-42. doi: 10.1016/j.bbacli.2015.03.002. eCollection 2015 Jun.

14.

Anaesthesia and perioperative care in remote health camps: patients' concerns.

Bhattarai B, Ghimire A, Baral BK, Shrestha A, Dhungana Y.

JNMA J Nepal Med Assoc. 2010 Jul-Sep;49(179):195-8.

PMID:
22049822
15.

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