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Items: 39


Moving Immunoprevention Beyond Virally Mediated Malignancies: Do We Need to Link It to Early Detection?

Dhodapkar MV, Dhodapkar KM.

Front Immunol. 2019 Oct 10;10:2385. doi: 10.3389/fimmu.2019.02385. eCollection 2019. Review.


Autoimmune complications of cancer immunotherapy.

Dhodapkar KM.

Curr Opin Immunol. 2019 Sep 23;61:54-59. doi: 10.1016/j.coi.2019.08.004. [Epub ahead of print] Review.


Early alterations in stem-like/resident T cells, innate and myeloid cells in the bone marrow in preneoplastic gammopathy.

Bailur JK, McCachren SS, Doxie DB, Shrestha M, Pendleton K, Nooka AK, Neparidze N, Parker TL, Bar N, Kaufman JL, Hofmeister CC, Boise LH, Lonial S, Kemp ML, Dhodapkar KM, Dhodapkar MV.

JCI Insight. 2019 Apr 23;5. pii: 127807. doi: 10.1172/jci.insight.127807.


Role of Tissue-Resident Memory in Intra-Tumor Heterogeneity and Response to Immune Checkpoint Blockade.

Dhodapkar KM.

Front Immunol. 2018 Jul 16;9:1655. doi: 10.3389/fimmu.2018.01655. eCollection 2018. Review.


Early B cell changes predict autoimmunity following combination immune checkpoint blockade.

Das R, Bar N, Ferreira M, Newman AM, Zhang L, Bailur JK, Bacchiocchi A, Kluger H, Wei W, Halaban R, Sznol M, Dhodapkar MV, Dhodapkar KM.

J Clin Invest. 2018 Feb 1;128(2):715-720. doi: 10.1172/JCI96798. Epub 2018 Jan 8.


Changes in bone marrow innate lymphoid cell subsets in monoclonal gammopathy: target for IMiD therapy.

Kini Bailur J, Mehta S, Zhang L, Neparidze N, Parker T, Bar N, Anderson T, Xu ML, Dhodapkar KM, Dhodapkar MV.

Blood Adv. 2017 Nov 20;1(25):2343-2347. doi: 10.1182/bloodadvances.2017012732. eCollection 2017 Nov 28. Erratum in: Blood Adv. 2018 Jan 09;2(1):75. Blood Adv. 2018 Jan 9;2(1):75.


SOX2 immunity and tissue resident memory in children and young adults with glioma.

Vasquez JC, Huttner A, Zhang L, Marks A, Chan A, Baehring JM, Kahle KT, Dhodapkar KM.

J Neurooncol. 2017 Aug;134(1):41-53. doi: 10.1007/s11060-017-2515-8. Epub 2017 Jun 15.


Interlesional diversity of T cell receptors in melanoma with immune checkpoints enriched in tissue-resident memory T cells.

Boddupalli CS, Bar N, Kadaveru K, Krauthammer M, Pornputtapong N, Mai Z, Ariyan S, Narayan D, Kluger H, Deng Y, Verma R, Das R, Bacchiocchi A, Halaban R, Sznol M, Dhodapkar MV, Dhodapkar KM.

JCI Insight. 2016 Dec 22;1(21):e88955. doi: 10.1172/jci.insight.88955.


ABC transporters and NR4A1 identify a quiescent subset of tissue-resident memory T cells.

Boddupalli CS, Nair S, Gray SM, Nowyhed HN, Verma R, Gibson JA, Abraham C, Narayan D, Vasquez J, Hedrick CC, Flavell RA, Dhodapkar KM, Kaech SM, Dhodapkar MV.

J Clin Invest. 2016 Oct 3;126(10):3905-3916. doi: 10.1172/JCI85329. Epub 2016 Sep 12.


Prospective analysis of antigen-specific immunity, stem-cell antigens, and immune checkpoints in monoclonal gammopathy.

Dhodapkar MV, Sexton R, Das R, Dhodapkar KM, Zhang L, Sundaram R, Soni S, Crowley JJ, Orlowski RZ, Barlogie B.

Blood. 2015 Nov 26;126(22):2475-8. doi: 10.1182/blood-2015-03-632919. Epub 2015 Oct 14.


Immune Modulation in Hematologic Malignancies.

Dhodapkar MV, Dhodapkar KM.

Semin Oncol. 2015 Aug;42(4):617-25. doi: 10.1053/j.seminoncol.2015.05.009. Epub 2015 Jun 3. Review.


Clinical and pharmacodynamic analysis of pomalidomide dosing strategies in myeloma: impact of immune activation and cereblon targets.

Sehgal K, Das R, Zhang L, Verma R, Deng Y, Kocoglu M, Vasquez J, Koduru S, Ren Y, Wang M, Couto S, Breider M, Hansel D, Seropian S, Cooper D, Thakurta A, Yao X, Dhodapkar KM, Dhodapkar MV.

Blood. 2015 Jun 25;125(26):4042-51. doi: 10.1182/blood-2014-11-611426. Epub 2015 Apr 13.


Recent advances and new opportunities for targeting human dendritic cells in situ.

Dhodapkar MV, Dhodapkar KM.

Oncoimmunology. 2014 Aug 3;3(8):e954832. eCollection 2014.


Combination therapy with anti-CTLA-4 and anti-PD-1 leads to distinct immunologic changes in vivo.

Das R, Verma R, Sznol M, Boddupalli CS, Gettinger SN, Kluger H, Callahan M, Wolchok JD, Halaban R, Dhodapkar MV, Dhodapkar KM.

J Immunol. 2015 Feb 1;194(3):950-9. doi: 10.4049/jimmunol.1401686. Epub 2014 Dec 24.


Nanoparticle-mediated combinatorial targeting of multiple human dendritic cell (DC) subsets leads to enhanced T cell activation via IL-15-dependent DC crosstalk.

Sehgal K, Ragheb R, Fahmy TM, Dhodapkar MV, Dhodapkar KM.

J Immunol. 2014 Sep 1;193(5):2297-305. doi: 10.4049/jimmunol.1400489. Epub 2014 Jul 30.


Targeting human dendritic cells in situ to improve vaccines.

Sehgal K, Dhodapkar KM, Dhodapkar MV.

Immunol Lett. 2014 Nov;162(1 Pt A):59-67. doi: 10.1016/j.imlet.2014.07.004. Epub 2014 Jul 27. Review.


SOX2-specific adaptive immunity and response to immunotherapy in non-small cell lung cancer.

Dhodapkar KM, Gettinger SN, Das R, Zebroski H, Dhodapkar MV.

Oncoimmunology. 2013 Jul 1;2(7):e25205. Epub 2013 Jun 10.


Plasmacytoid dendritic cells, interferon signaling, and FcγR contribute to pathogenesis and therapeutic response in childhood immune thrombocytopenia.

Sehgal K, Guo X, Koduru S, Shah A, Lin A, Yan X, Dhodapkar KM.

Sci Transl Med. 2013 Jul 10;5(193):193ra89. doi: 10.1126/scitranslmed.3006277.


Clinical regressions and broad immune activation following combination therapy targeting human NKT cells in myeloma.

Richter J, Neparidze N, Zhang L, Nair S, Monesmith T, Sundaram R, Miesowicz F, Dhodapkar KM, Dhodapkar MV.

Blood. 2013 Jan 17;121(3):423-30. doi: 10.1182/blood-2012-06-435503. Epub 2012 Oct 24.


Central and overlapping role of Cathepsin B and inflammasome adaptor ASC in antigen presenting function of human dendritic cells.

Guo X, Dhodapkar KM.

Hum Immunol. 2012 Sep;73(9):871-8. doi: 10.1016/j.humimm.2012.06.008. Epub 2012 Jun 22.


Dendritic cell-mediated activation-induced cytidine deaminase (AID)-dependent induction of genomic instability in human myeloma.

Koduru S, Wong E, Strowig T, Sundaram R, Zhang L, Strout MP, Flavell RA, Schatz DG, Dhodapkar KM, Dhodapkar MV.

Blood. 2012 Mar 8;119(10):2302-9. doi: 10.1182/blood-2011-08-376236. Epub 2012 Jan 10.


Vaccines targeting cancer stem cells: are they within reach?

Dhodapkar MV, Dhodapkar KM.

Cancer J. 2011 Sep-Oct;17(5):397-402. doi: 10.1097/PPO.0b013e318233e730. Review.


Spontaneous and therapy-induced immunity to pluripotency genes in humans: clinical implications, opportunities and challenges.

Dhodapkar MV, Dhodapkar KM.

Cancer Immunol Immunother. 2011 Mar;60(3):413-8. doi: 10.1007/s00262-010-0944-8. Epub 2010 Nov 23. Review.


Natural immunity to pluripotency antigen OCT4 in humans.

Dhodapkar KM, Feldman D, Matthews P, Radfar S, Pickering R, Turkula S, Zebroski H, Dhodapkar MV.

Proc Natl Acad Sci U S A. 2010 May 11;107(19):8718-23. doi: 10.1073/pnas.0915086107. Epub 2010 Apr 19.


Dendritic cells mediate the induction of polyfunctional human IL17-producing cells (Th17-1 cells) enriched in the bone marrow of patients with myeloma.

Dhodapkar KM, Barbuto S, Matthews P, Kukreja A, Mazumder A, Vesole D, Jagannath S, Dhodapkar MV.

Blood. 2008 Oct 1;112(7):2878-85. doi: 10.1182/blood-2008-03-143222. Epub 2008 Jul 30.


Role of chaperones and FcgammaR in immunogenic death.

Dhodapkar MV, Dhodapkar KM, Li Z.

Curr Opin Immunol. 2008 Oct;20(5):512-7. doi: 10.1016/j.coi.2008.05.002. Epub 2008 Jun 21. Review.


Enhanced T-cell responses to glioma cells coated with the anti-EGF receptor antibody and targeted to activating FcgammaRs on human dendritic cells.

Banerjee D, Matthews P, Matayeva E, Kaufman JL, Steinman RM, Dhodapkar KM.

J Immunother. 2008 Feb-Mar;31(2):113-20. doi: 10.1097/CJI.0b013e31815a5892.


Interactions of tumor cells with dendritic cells: balancing immunity and tolerance.

Dhodapkar MV, Dhodapkar KM, Palucka AK.

Cell Death Differ. 2008 Jan;15(1):39-50. Epub 2007 Oct 19. Review.


Selective blockade of the inhibitory Fcgamma receptor (FcgammaRIIB) in human dendritic cells and monocytes induces a type I interferon response program.

Dhodapkar KM, Banerjee D, Connolly J, Kukreja A, Matayeva E, Veri MC, Ravetch JV, Steinman RM, Dhodapkar MV.

J Exp Med. 2007 Jun 11;204(6):1359-69. Epub 2007 May 14. Erratum in: J Exp Med. 2007 Oct;204(10):2489.


Expansion of FOXP3high regulatory T cells by human dendritic cells (DCs) in vitro and after injection of cytokine-matured DCs in myeloma patients.

Banerjee DK, Dhodapkar MV, Matayeva E, Steinman RM, Dhodapkar KM.

Blood. 2006 Oct 15;108(8):2655-61. Epub 2006 Jun 8.


Harnessing the immune system against human glioma.

Dhodapkar KM, Banerjee D, Steinman RM.

Ann N Y Acad Sci. 2005 Dec;1062:13-21. Review.


Recruiting dendritic cells to improve antibody therapy of cancer.

Dhodapkar KM, Dhodapkar MV.

Proc Natl Acad Sci U S A. 2005 May 3;102(18):6243-4. Epub 2005 Apr 25. No abstract available.


Selective blockade of inhibitory Fcgamma receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells.

Dhodapkar KM, Kaufman JL, Ehlers M, Banerjee DK, Bonvini E, Koenig S, Steinman RM, Ravetch JV, Dhodapkar MV.

Proc Natl Acad Sci U S A. 2005 Feb 22;102(8):2910-5. Epub 2005 Feb 9.


Invariant natural killer T cells are preserved in patients with glioma and exhibit antitumor lytic activity following dendritic cell-mediated expansion.

Dhodapkar KM, Cirignano B, Chamian F, Zagzag D, Miller DC, Finlay JL, Steinman RM.

Int J Cancer. 2004 May 10;109(6):893-9.


A reversible defect in natural killer T cell function characterizes the progression of premalignant to malignant multiple myeloma.

Dhodapkar MV, Geller MD, Chang DH, Shimizu K, Fujii S, Dhodapkar KM, Krasovsky J.

J Exp Med. 2003 Jun 16;197(12):1667-76. Epub 2003 Jun 9.


Differential expression of the cell-adhesion molecule Nr-CAM in hyperplastic and neoplastic human pancreatic tissue.

Dhodapkar KM, Friedlander D, Scholes J, Grumet M.

Hum Pathol. 2001 Apr;32(4):396-400.


Treatment of hemolytic disease of the newborn caused by anti-Kell antibody with recombinant erythropoietin.

Dhodapkar KM, Blei F.

J Pediatr Hematol Oncol. 2001 Jan;23(1):69-70.


Leuconostoc bacteremia in an infant with short-gut syndrome: case report and literature review.

Dhodapkar KM, Henry NK.

Mayo Clin Proc. 1996 Dec;71(12):1171-4. Review.


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