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Arabidopsis defense mutant ndr1-1 displays accelerated development and early flowering mediated by the hormone gibberellic acid.

Dhar N, Short DPG, Mamo BE, Corrion AJ, Wai CM, Anchieta A, VanBuren R, Day B, Ajwa H, Subbarao KV, Klosterman SJ.

Plant Sci. 2019 Aug;285:200-213. doi: 10.1016/j.plantsci.2019.04.006. Epub 2019 Apr 11.


Exfoliation Behavior of van der Waals Strings: Case Study of Bi2S3.

Dhar N, Syed N, Mohiuddin M, Jannat A, Zavabeti A, Zhang BY, Datta RS, Atkin P, Mahmood N, Esrafilzadeh D, Daeneke T, Kalantar-Zadeh K.

ACS Appl Mater Interfaces. 2018 Dec 12;10(49):42603-42611. doi: 10.1021/acsami.8b14702. Epub 2018 Nov 28.


Fluorescent Benzothiazinone Analogues Efficiently and Selectively Label Dpre1 in Mycobacteria and Actinobacteria.

Sommer R, Neres J, Piton J, Dhar N, van der Sar A, Mukherjee R, Laroche T, Dyson PJ, McKinney JD, Bitter W, Makarov V, Cole ST.

ACS Chem Biol. 2018 Nov 16;13(11):3184-3192. doi: 10.1021/acschembio.8b00790. Epub 2018 Oct 25.


Genome-Wide Identification and Functional Analyses of the CRK Gene Family in Cotton Reveals GbCRK18 Confers Verticillium Wilt Resistance in Gossypium barbadense.

Li TG, Zhang DD, Zhou L, Kong ZQ, Hussaini AS, Wang D, Li JJ, Short DPG, Dhar N, Klosterman SJ, Wang BL, Yin CM, Subbarao KV, Chen JY, Dai XF.

Front Plant Sci. 2018 Sep 11;9:1266. doi: 10.3389/fpls.2018.01266. eCollection 2018.


Understanding How Wnt Influences Destruction Complex Activity and β-Catenin Dynamics.

Mukherjee A, Dhar N, Stathos M, Schaffer DV, Kane RS.

iScience. 2018 Aug 31;6:13-21. doi: 10.1016/j.isci.2018.07.007. Epub 2018 Jul 17.


Detection of Latent Peronospora effusa Infections in Spinach.

Subbarao CS, Anchieta A, Ochoa L, Dhar N, Kunjeti SG, Subbarao KV, Klosterman SJ.

Plant Dis. 2018 Sep;102(9):1766-1771. doi: 10.1094/PDIS-12-17-1956-RE. Epub 2018 Jul 23.


Elucidating the role of (p)ppGpp in mycobacterial persistence against antibiotics.

Bhaskar A, De Piano C, Gelman E, McKinney JD, Dhar N.

IUBMB Life. 2018 Sep;70(9):836-844. doi: 10.1002/iub.1888. Epub 2018 Aug 9. Review.


Molecular trade-offs in RNA ligases affected the modular emergence of complex ribozymes at the origin of life.

Dhar N, Weinberg MS, Michod RE, Durand PM.

R Soc Open Sci. 2017 Sep 20;4(9):170376. doi: 10.1098/rsos.170376. eCollection 2017 Sep.


Division site selection linked to inherited cell surface wave troughs in mycobacteria.

Eskandarian HA, Odermatt PD, Ven JXY, Hannebelle MTM, Nievergelt AP, Dhar N, McKinney JD, Fantner GE.

Nat Microbiol. 2017 Jun 26;2:17094. doi: 10.1038/nmicrobiol.2017.94.


An Amidase_3 domain-containing N-acetylmuramyl-L-alanine amidase is required for mycobacterial cell division.

Senzani S, Li D, Bhaskar A, Ealand C, Chang J, Rimal B, Liu C, Joon Kim S, Dhar N, Kana B.

Sci Rep. 2017 Apr 25;7(1):1140. doi: 10.1038/s41598-017-01184-7.


Spearmint R2R3-MYB transcription factor MsMYB negatively regulates monoterpene production and suppresses the expression of geranyl diphosphate synthase large subunit (MsGPPS.LSU).

Reddy VA, Wang Q, Dhar N, Kumar N, Venkatesh PN, Rajan C, Panicker D, Sridhar V, Mao HZ, Sarojam R.

Plant Biotechnol J. 2017 Sep;15(9):1105-1119. doi: 10.1111/pbi.12701. Epub 2017 Mar 18.


Phenotypic Heterogeneity in Mycobacterium tuberculosis.

Dhar N, McKinney J, Manina G.

Microbiol Spectr. 2016 Nov;4(6). doi: 10.1128/microbiolspec.TBTB2-0021-2016. Review.


Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria.

Singh V, Dhar N, Pató J, Kolly GS, Korduláková J, Forbak M, Evans JC, Székely R, Rybniker J, Palčeková Z, Zemanová J, Santi I, Signorino-Gelo F, Rodrigues L, Vocat A, Covarrubias AS, Rengifo MG, Johnsson K, Mowbray S, Buechler J, Delorme V, Brodin P, Knott GW, Aínsa JA, Warner DF, Kéri G, Mikušová K, McKinney JD, Cole ST, Mizrahi V, Hartkoorn RC.

Mol Microbiol. 2017 Jan;103(1):13-25. doi: 10.1111/mmi.13535. Epub 2016 Oct 29.


The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis.

Singh V, Donini S, Pacitto A, Sala C, Hartkoorn RC, Dhar N, Keri G, Ascher DB, Mondésert G, Vocat A, Lupien A, Sommer R, Vermet H, Lagrange S, Buechler J, Warner DF, McKinney JD, Pato J, Cole ST, Blundell TL, Rizzi M, Mizrahi V.

ACS Infect Dis. 2017 Jan 13;3(1):5-17. doi: 10.1021/acsinfecdis.6b00102. Epub 2016 Sep 8.


Whole Cell Target Engagement Identifies Novel Inhibitors of Mycobacterium tuberculosis Decaprenylphosphoryl-β-d-ribose Oxidase.

Batt SM, Cacho Izquierdo M, Castro Pichel J, Stubbs CJ, Vela-Glez Del Peral L, Pérez-Herrán E, Dhar N, Mouzon B, Rees M, Hutchinson JP, Young RJ, McKinney JD, Barros Aguirre D, Ballell L, Besra GS, Argyrou A.

ACS Infect Dis. 2015 Dec 11;1(12):615-26. doi: 10.1021/acsinfecdis.5b00065. Epub 2015 Aug 25.


Antitubercular drugs for an old target: GSK693 as a promising InhA direct inhibitor.

Martínez-Hoyos M, Perez-Herran E, Gulten G, Encinas L, Álvarez-Gómez D, Alvarez E, Ferrer-Bazaga S, García-Pérez A, Ortega F, Angulo-Barturen I, Rullas-Trincado J, Blanco Ruano D, Torres P, Castañeda P, Huss S, Fernández Menéndez R, González Del Valle S, Ballell L, Barros D, Modha S, Dhar N, Signorino-Gelo F, McKinney JD, García-Bustos JF, Lavandera JL, Sacchettini JC, Jimenez MS, Martín-Casabona N, Castro-Pichel J, Mendoza-Losana A.

EBioMedicine. 2016 Jun;8:291-301. doi: 10.1016/j.ebiom.2016.05.006. Epub 2016 May 8.


Functional Promiscuity of Two Divergent Paralogs of Type III Plant Polyketide Synthases.

Pandith SA, Dhar N, Rana S, Bhat WW, Kushwaha M, Gupta AP, Shah MA, Vishwakarma R, Lattoo SK.

Plant Physiol. 2016 Aug;171(4):2599-619. doi: 10.1104/pp.16.00003. Epub 2016 Jun 7.


Dissecting the structural and functional features of the Luteinizing hormone receptor using receptor specific single chain fragment variables.

Dhar N, Mohan A, Thakur C, Chandra NR, Dighe RR.

Mol Cell Endocrinol. 2016 May 15;427:1-12. doi: 10.1016/j.mce.2016.02.022. Epub 2016 Mar 3.


Site-Specific Thiol-mediated PEGylation of Streptokinase Leads to Improved Properties with Clinical Potential.

Sawhney P, Kumar S, Maheshwari N, Guleria SS, Dhar N, Kashyap R, Sahni G.

Curr Pharm Des. 2016;22(38):5868-5878.


A Comprehensive Study on Mo/CdTe Metal-Semiconductor Interface Deposited by Radio Frequency Magnetron Sputtering.

Dhar N, Khan NA, Chelvanathan P, Akhtaruzzaman M, Alam MM, Alothman ZA, Sopian K, Amin N.

J Nanosci Nanotechnol. 2015 Nov;15(11):9291-7.


A Decade of Molecular Understanding of Withanolide Biosynthesis and In vitro Studies in Withania somnifera (L.) Dunal: Prospects and Perspectives for Pathway Engineering.

Dhar N, Razdan S, Rana S, Bhat WW, Vishwakarma R, Lattoo SK.

Front Plant Sci. 2015 Nov 27;6:1031. doi: 10.3389/fpls.2015.01031. eCollection 2015. Review.


Atomically thin layers of B-N-C-O with tunable composition.

Ozturk B, de-Luna-Bugallo A, Panaitescu E, Chiaramonti AN, Liu F, Vargas A, Jiang X, Kharche N, Yavuzcetin O, Alnaji M, Ford MJ, Lok J, Zhao Y, King N, Dhar NK, Dubey M, Nayak SK, Sridhar S, Kar S.

Sci Adv. 2015 Jul 31;1(6):e1500094. doi: 10.1126/sciadv.1500094. eCollection 2015 Jul.


A pretreatment nomogram for prediction of biochemical failure after primary cryoablation of the prostate.

Elshafei A, Kovac E, Dhar N, Levy D, Polascik T, Mouraviev V, Yu C, Jones JS.

Prostate. 2015 Sep;75(13):1447-53. doi: 10.1002/pros.23030. Epub 2015 Jul 14.


Combinations of β-Lactam Antibiotics Currently in Clinical Trials Are Efficacious in a DHP-I-Deficient Mouse Model of Tuberculosis Infection.

Rullas J, Dhar N, McKinney JD, García-Pérez A, Lelievre J, Diacon AH, Hugonnet JE, Arthur M, Angulo-Barturen I, Barros-Aguirre D, Ballell L.

Antimicrob Agents Chemother. 2015 Aug;59(8):4997-9. doi: 10.1128/AAC.01063-15. Epub 2015 May 18.


Bioluminescence for assessing drug potency against nonreplicating Mycobacterium tuberculosis.

Vocat A, Hartkoorn RC, Lechartier B, Zhang M, Dhar N, Cole ST, Sala C.

Antimicrob Agents Chemother. 2015 Jul;59(7):4012-9. doi: 10.1128/AAC.00528-15. Epub 2015 Apr 20.


Single-cell analysis of mycobacteria using microfluidics and time-lapse microscopy.

Dhar N, Manina G.

Methods Mol Biol. 2015;1285:241-56. doi: 10.1007/978-1-4939-2450-9_14.


Stressed mycobacteria use the chaperone ClpB to sequester irreversibly oxidized proteins asymmetrically within and between cells.

Vaubourgeix J, Lin G, Dhar N, Chenouard N, Jiang X, Botella H, Lupoli T, Mariani O, Yang G, Ouerfelli O, Unser M, Schnappinger D, McKinney J, Nathan C.

Cell Host Microbe. 2015 Feb 11;17(2):178-90. doi: 10.1016/j.chom.2014.12.008. Epub 2015 Jan 22.


Stress and host immunity amplify Mycobacterium tuberculosis phenotypic heterogeneity and induce nongrowing metabolically active forms.

Manina G, Dhar N, McKinney JD.

Cell Host Microbe. 2015 Jan 14;17(1):32-46. doi: 10.1016/j.chom.2014.11.016. Epub 2014 Dec 24.


2-Carboxyquinoxalines kill mycobacterium tuberculosis through noncovalent inhibition of DprE1.

Neres J, Hartkoorn RC, Chiarelli LR, Gadupudi R, Pasca MR, Mori G, Venturelli A, Savina S, Makarov V, Kolly GS, Molteni E, Binda C, Dhar N, Ferrari S, Brodin P, Delorme V, Landry V, de Jesus Lopes Ribeiro AL, Farina D, Saxena P, Pojer F, Carta A, Luciani R, Porta A, Zanoni G, De Rossi E, Costi MP, Riccardi G, Cole ST.

ACS Chem Biol. 2015 Mar 20;10(3):705-14. doi: 10.1021/cb5007163. Epub 2014 Dec 9.


Rapid cytolysis of Mycobacterium tuberculosis by faropenem, an orally bioavailable β-lactam antibiotic.

Dhar N, Dubée V, Ballell L, Cuinet G, Hugonnet JE, Signorino-Gelo F, Barros D, Arthur M, McKinney JD.

Antimicrob Agents Chemother. 2015 Feb;59(2):1308-19. doi: 10.1128/AAC.03461-14. Epub 2014 Nov 24.


Molecular characterization of two A-type P450s, WsCYP98A and WsCYP76A from Withania somnifera (L.) Dunal: expression analysis and withanolide accumulation in response to exogenous elicitations.

Rana S, Bhat WW, Dhar N, Pandith SA, Razdan S, Vishwakarma R, Lattoo SK.

BMC Biotechnol. 2014 Nov 23;14:89. doi: 10.1186/s12896-014-0089-5.


Simple and rapid method to determine antimycobacterial potency of compounds by using autoluminescent Mycobacterium tuberculosis.

Sharma S, Gelman E, Narayan C, Bhattacharjee D, Achar V, Humnabadkar V, Balasubramanian V, Ramachandran V, Dhar N, Dinesh N.

Antimicrob Agents Chemother. 2014 Oct;58(10):5801-8. doi: 10.1128/AAC.03205-14. Epub 2014 Jul 21.


The phosphatidyl-myo-inositol mannosyltransferase PimA is essential for Mycobacterium tuberculosis growth in vitro and in vivo.

Boldrin F, Ventura M, Degiacomi G, Ravishankar S, Sala C, Svetlikova Z, Ambady A, Dhar N, Kordulakova J, Zhang M, Serafini A, Vishwas KG, Kolly GS, Kumar N, Palù G, Guerin ME, Mikusova K, Cole ST, Manganelli R.

J Bacteriol. 2014 Oct;196(19):3441-51. doi: 10.1128/JB.01346-13. Epub 2014 Jul 21. Erratum in: J Bacteriol. 2014 Dec;196(23):4197. Vishwas, V G [Corrected to Vishwas, K G].


EspI regulates the ESX-1 secretion system in response to ATP levels in Mycobacterium tuberculosis.

Zhang M, Chen JM, Sala C, Rybniker J, Dhar N, Cole ST.

Mol Microbiol. 2014 Sep;93(5):1057-1065. doi: 10.1111/mmi.12718. Epub 2014 Jul 31.


A phenylalanine ammonia-lyase ortholog (PkPAL1) from Picrorhiza kurrooa Royle ex. Benth: molecular cloning, promoter analysis and response to biotic and abiotic elicitors.

Bhat WW, Razdan S, Rana S, Dhar N, Wani TA, Qazi P, Vishwakarma R, Lattoo SK.

Gene. 2014 Sep 1;547(2):245-56. doi: 10.1016/j.gene.2014.06.046. Epub 2014 Jun 27.


4-aminoquinolone piperidine amides: noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity.

Naik M, Humnabadkar V, Tantry SJ, Panda M, Narayan A, Guptha S, Panduga V, Manjrekar P, Jena LK, Koushik K, Shanbhag G, Jatheendranath S, Manjunatha MR, Gorai G, Bathula C, Rudrapatna S, Achar V, Sharma S, Ambady A, Hegde N, Mahadevaswamy J, Kaur P, Sambandamurthy VK, Awasthy D, Narayan C, Ravishankar S, Madhavapeddi P, Reddy J, Prabhakar K, Saralaya R, Chatterji M, Whiteaker J, McLaughlin B, Chiarelli LR, Riccardi G, Pasca MR, Binda C, Neres J, Dhar N, Signorino-Gelo F, McKinney JD, Ramachandran V, Shandil R, Tommasi R, Iyer PS, Narayanan S, Hosagrahara V, Kavanagh S, Dinesh N, Ghorpade SR.

J Med Chem. 2014 Jun 26;57(12):5419-34. doi: 10.1021/jm5005978. Epub 2014 Jun 11.


Cloning and functional characterization of three branch point oxidosqualene cyclases from Withania somnifera (L.) dunal.

Dhar N, Rana S, Razdan S, Bhat WW, Hussain A, Dhar RS, Vaishnavi S, Hamid A, Vishwakarma R, Lattoo SK.

J Biol Chem. 2014 Jun 13;289(24):17249-67. doi: 10.1074/jbc.M114.571919. Epub 2014 Apr 25.


Dielectrophoresis-based purification of antibiotic-treated bacterial subpopulations.

Elitas M, Martinez-Duarte R, Dhar N, McKinney JD, Renaud P.

Lab Chip. 2014 Jun 7;14(11):1850-7. doi: 10.1039/c4lc00109e. Epub 2014 Apr 23.


In vitro and in vivo activities of three oxazolidinones against nonreplicating Mycobacterium tuberculosis.

Zhang M, Sala C, Dhar N, Vocat A, Sambandamurthy VK, Sharma S, Marriner G, Balasubramanian V, Cole ST.

Antimicrob Agents Chemother. 2014 Jun;58(6):3217-23. doi: 10.1128/AAC.02410-14. Epub 2014 Mar 24.


Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism.

Koul A, Vranckx L, Dhar N, Göhlmann HW, Özdemir E, Neefs JM, Schulz M, Lu P, Mørtz E, McKinney JD, Andries K, Bald D.

Nat Commun. 2014 Feb 26;5:3369. doi: 10.1038/ncomms4369.


An inducible NADPH-cytochrome P450 reductase from Picrorhiza kurrooa - an imperative redox partner of cytochrome P450 enzymes.

Bhat WW, Rana S, Dhar N, Razdan S, Pandith SA, Vishwakarma R, Lattoo SK.

Funct Integr Genomics. 2014 Jun;14(2):381-99. doi: 10.1007/s10142-014-0362-7. Epub 2014 Feb 13.


Assessing the essentiality of the decaprenyl-phospho-d-arabinofuranose pathway in Mycobacterium tuberculosis using conditional mutants.

Kolly GS, Boldrin F, Sala C, Dhar N, Hartkoorn RC, Ventura M, Serafini A, McKinney JD, Manganelli R, Cole ST.

Mol Microbiol. 2014 Apr;92(1):194-211. doi: 10.1111/mmi.12546. Epub 2014 Mar 7.


Dynamics of withanolide biosynthesis in relation to temporal expression pattern of metabolic genes in Withania somnifera (L.) Dunal: a comparative study in two morpho-chemovariants.

Dhar N, Rana S, Bhat WW, Razdan S, Pandith SA, Khan S, Dutt P, Dhar RS, Vaishnavi S, Vishwakarma R, Lattoo SK.

Mol Biol Rep. 2013 Dec;40(12):7007-16. doi: 10.1007/s11033-013-2820-z. Epub 2013 Nov 5.


Phenotypic profiling of Mycobacterium tuberculosis EspA point mutants reveals that blockage of ESAT-6 and CFP-10 secretion in vitro does not always correlate with attenuation of virulence.

Chen JM, Zhang M, Rybniker J, Basterra L, Dhar N, Tischler AD, Pojer F, Cole ST.

J Bacteriol. 2013 Dec;195(24):5421-30. doi: 10.1128/JB.00967-13. Epub 2013 Sep 27.


Molecular characterization of UGT94F2 and UGT86C4, two glycosyltransferases from Picrorhiza kurrooa: comparative structural insight and evaluation of substrate recognition.

Bhat WW, Dhar N, Razdan S, Rana S, Mehra R, Nargotra A, Dhar RS, Ashraf N, Vishwakarma R, Lattoo SK.

PLoS One. 2013 Sep 16;8(9):e73804. doi: 10.1371/journal.pone.0073804. eCollection 2013.


Single-cell dynamics of the chromosome replication and cell division cycles in mycobacteria.

Santi I, Dhar N, Bousbaine D, Wakamoto Y, McKinney JD.

Nat Commun. 2013;4:2470. doi: 10.1038/ncomms3470. Erratum in: Nat Commun. 2013;4:3913.


Mycobacterium tuberculosis EspB binds phospholipids and mediates EsxA-independent virulence.

Chen JM, Zhang M, Rybniker J, Boy-Röttger S, Dhar N, Pojer F, Cole ST.

Mol Microbiol. 2013 Sep;89(6):1154-66. doi: 10.1111/mmi.12336. Epub 2013 Aug 15.


Dengue-specific subviral nanoparticles: design, creation and characterization.

Khetarpal N, Poddar A, Nemani SK, Dhar N, Patil A, Negi P, Perween A, Viswanathan R, Lünsdorf H, Tyagi P, Raut R, Arora U, Jain SK, Rinas U, Swaminathan S, Khanna N.

J Nanobiotechnology. 2013 May 25;11:15. doi: 10.1186/1477-3155-11-15.


Self evolution: 1(st) domain of spiritual health.

Dhar N, Chaturvedi SK, Nandan D.

Ayu. 2012 Apr;33(2):174-7. doi: 10.4103/0974-8520.105234.

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