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Items: 32


Prophylactic supplementation of 20-HETE ameliorates hypoxia/reoxygenation injury in pulmonary vascular endothelial cells by inhibiting apoptosis.

Sugumaran P, Narayanan V, Zhu D, Medhora M, Jacobs ER, Chandramohan Y, Selvaraj V, Dhanasekaran A.

Acta Histochem. 2019 Nov 6:151461. doi: 10.1016/j.acthis.2019.151461. [Epub ahead of print]


Genome-wide differential expression profiling of lncRNAs and mRNAs associated with early diabetic cardiomyopathy.

Pant T, Dhanasekaran A, Bai X, Zhao M, Thorp EB, Forbess JM, Bosnjak ZJ, Ge ZD.

Sci Rep. 2019 Oct 25;9(1):15345. doi: 10.1038/s41598-019-51872-9.


Feasibility of home-based automated transcranial electrical stimulation during slow wave sleep.

McConnell BV, Kaplan RI, Teale PD, Kronberg E, Broussard JL, Guzetti JR, Sillau SH, Dhanasekaran AR, Kluger BM, Berman BD.

Brain Stimul. 2019 May - Jun;12(3):813-815. doi: 10.1016/j.brs.2019.02.014. Epub 2019 Feb 20. No abstract available.


Immune Response to Brugia malayi Asparaginyl-tRNA Synthetase in Balb/c Mice and Human Clinical Samples of Lymphatic Filariasis.

Hameed A, Natarajan M, Jabbar S, Dhanasekaran JJ, Kumar K, Sivanesan S, Kron M, Dhanasekaran A.

Lymphat Res Biol. 2019 Aug;17(4):447-456. doi: 10.1089/lrb.2018.0003. Epub 2018 Dec 20.


Microarray analysis of long non-coding RNA and mRNA expression profiles in diabetic cardiomyopathy using human induced pluripotent stem cell-derived cardiomyocytes.

Pant T, Mishra MK, Bai X, Ge ZD, Bosnjak ZJ, Dhanasekaran A.

Diab Vasc Dis Res. 2019 Jan;16(1):57-68. doi: 10.1177/1479164118813888. Epub 2018 Nov 28.


Current status and strategies of long noncoding RNA research for diabetic cardiomyopathy.

Pant T, Dhanasekaran A, Fang J, Bai X, Bosnjak ZJ, Liang M, Ge ZD.

BMC Cardiovasc Disord. 2018 Oct 20;18(1):197. doi: 10.1186/s12872-018-0939-5. Review.


Uncoupling Warburg effect and stemness in CD133+ve cancer stem cells from Saos-2 (osteosarcoma) cell line under hypoxia.

Koka P, Mundre RS, Rangarajan R, Chandramohan Y, Subramanian RK, Dhanasekaran A.

Mol Biol Rep. 2018 Dec;45(6):1653-1662. doi: 10.1007/s11033-018-4309-2. Epub 2018 Aug 20.


Synergistic role of 5-azacytidine and ascorbic acid in directing cardiosphere derived cells to cardiomyocytes in vitro by downregulating Wnt signaling pathway via phosphorylation of β-catenin.

Mundre RS, Koka P, Dhanaraj P, Khatri N, Vig S, Chandramohan Y, Dhanasekaran A.

PLoS One. 2017 Nov 30;12(11):e0188805. doi: 10.1371/journal.pone.0188805. eCollection 2017.


Effect of mitochondrially targeted carboxy proxyl nitroxide on Akt-mediated survival in Daudi cells: Significance of a dual mode of action.

Variar G, Pant T, Singh A, Ravichandran A, Swami S, Kalyanaraman B, Dhanasekaran A.

PLoS One. 2017 Apr 20;12(4):e0174546. doi: 10.1371/journal.pone.0174546. eCollection 2017.


Correction: Brugia malayi Asparaginyl-tRNA Synthetase Stimulates Endothelial Cell Proliferation, Vasodilation and Angiogenesis.

D JJ, Dhanraj M, Solaiappan S, Sivanesan S, Kron M, Dhanasekaran A.

PLoS One. 2017 Feb 2;12(2):e0171402. doi: 10.1371/journal.pone.0171402. eCollection 2017.


Mouse models of Down syndrome: gene content and consequences.

Gupta M, Dhanasekaran AR, Gardiner KJ.

Mamm Genome. 2016 Dec;27(11-12):538-555. Epub 2016 Aug 18. Review.


How to review a case report.

Garg R, Lakhan SE, Dhanasekaran AK.

J Med Case Rep. 2016 Apr 6;10:88. doi: 10.1186/s13256-016-0853-3. No abstract available.


MicroRNA: A new therapeutic strategy for cardiovascular diseases.

Samanta S, Balasubramanian S, Rajasingh S, Patel U, Dhanasekaran A, Dawn B, Rajasingh J.

Trends Cardiovasc Med. 2016 Jul;26(5):407-19. doi: 10.1016/j.tcm.2016.02.004. Epub 2016 Mar 3. Review.


Brugia malayi Asparaginyl-tRNA Synthetase Stimulates Endothelial Cell Proliferation, Vasodilation and Angiogenesis.

D JJ, Dhanraj M, Solaiappan S, Sivanesan S, Kron M, Dhanasekaran A.

PLoS One. 2016 Jan 11;11(1):e0146132. doi: 10.1371/journal.pone.0146132. eCollection 2016. Erratum in: PLoS One. 2017 Feb 2;12 (2):e0171402.


Sex differences in protein expression in the mouse brain and their perturbations in a model of Down syndrome.

Block A, Ahmed MM, Dhanasekaran AR, Tong S, Gardiner KJ.

Biol Sex Differ. 2015 Nov 9;6:24. doi: 10.1186/s13293-015-0043-9. eCollection 2015.


Randomized double blinded placebo controlled trial comparing diclofenac and piroxicam in management of acute renal colic and its clinical implications.

KandaSwamy GV, Dhanasekaran AK, Elangovan A, John B, Viswaroop B, Vedanayagam KS.

Urol J. 2015 Apr 29;12(2):2069-73.


Metabolome searcher: a high throughput tool for metabolite identification and metabolic pathway mapping directly from mass spectrometry and using genome restriction.

Dhanasekaran AR, Pearson JL, Ganesan B, Weimer BC.

BMC Bioinformatics. 2015 Feb 25;16:62. doi: 10.1186/s12859-015-0462-y.


Protein dynamics associated with failed and rescued learning in the Ts65Dn mouse model of Down syndrome.

Ahmed MM, Dhanasekaran AR, Block A, Tong S, Costa AC, Stasko M, Gardiner KJ.

PLoS One. 2015 Mar 20;10(3):e0119491. doi: 10.1371/journal.pone.0119491. eCollection 2015.


Thrombopoietin receptor agonists protect human cardiac myocytes from injury by activation of cell survival pathways.

Baker JE, Su J, Koprowski S, Dhanasekaran A, Aufderheide TP, Gross GJ.

J Pharmacol Exp Ther. 2015 Mar;352(3):429-37. doi: 10.1124/jpet.114.221747. Epub 2014 Dec 15.


Erythropoietin protects cardiomyocytes from cell death during hypoxia/reperfusion injury through activation of survival signaling pathways.

Parvin A, Pranap R, Shalini U, Devendran A, Baker JE, Dhanasekaran A.

PLoS One. 2014 Sep 19;9(9):e107453. doi: 10.1371/journal.pone.0107453. eCollection 2014. Erratum in: PLoS One. 2014;9(12):e115268.


Protein profiles associated with context fear conditioning and their modulation by memantine.

Ahmed MM, Dhanasekaran AR, Block A, Tong S, Costa AC, Gardiner KJ.

Mol Cell Proteomics. 2014 Apr;13(4):919-37. doi: 10.1074/mcp.M113.035568. Epub 2014 Jan 27.


Protein profiles in Tc1 mice implicate novel pathway perturbations in the Down syndrome brain.

Ahmed MM, Dhanasekaran AR, Tong S, Wiseman FK, Fisher EM, Tybulewicz VL, Gardiner KJ.

Hum Mol Genet. 2013 May 1;22(9):1709-24. doi: 10.1093/hmg/ddt017. Epub 2013 Jan 24.


Chemometric formulation of bacterial consortium-AVS for improved decolorization of resonance-stabilized and heteropolyaromatic dyes.

Kumar MA, Kumar VV, Premkumar MP, Baskaralingam P, Thiruvengadaravi KV, Dhanasekaran A, Sivanesan S.

Bioresour Technol. 2012 Nov;123:344-51. doi: 10.1016/j.biortech.2012.06.089. Epub 2012 Jul 4.


Tissue protection and endothelial cell signaling by 20-HETE analogs in intact ex vivo lung slices.

Jacobs ER, Bodiga S, Ali I, Falck AM, Falck JR, Medhora M, Dhanasekaran A.

Exp Cell Res. 2012 Oct 1;318(16):2143-52. doi: 10.1016/j.yexcr.2012.06.005. Epub 2012 Jun 9.


20-HETE increases survival and decreases apoptosis in pulmonary arteries and pulmonary artery endothelial cells.

Dhanasekaran A, Bodiga S, Gruenloh S, Gao Y, Dunn L, Falck JR, Buonaccorsi JN, Medhora M, Jacobs ER.

Am J Physiol Heart Circ Physiol. 2009 Mar;296(3):H777-86. doi: 10.1152/ajpheart.01087.2008. Epub 2009 Jan 9.


Role of JNK in network formation of human lung microvascular endothelial cells.

Medhora M, Dhanasekaran A, Pratt PF Jr, Cook CR, Dunn LK, Gruenloh SK, Jacobs ER.

Am J Physiol Lung Cell Mol Physiol. 2008 Apr;294(4):L676-85. doi: 10.1152/ajplung.00496.2007. Epub 2008 Feb 8.


Multiple antiapoptotic targets of the PI3K/Akt survival pathway are activated by epoxyeicosatrienoic acids to protect cardiomyocytes from hypoxia/anoxia.

Dhanasekaran A, Gruenloh SK, Buonaccorsi JN, Zhang R, Gross GJ, Falck JR, Patel PK, Jacobs ER, Medhora M.

Am J Physiol Heart Circ Physiol. 2008 Feb;294(2):H724-35. Epub 2007 Nov 30.


Emerging mechanisms for growth and protection of the vasculature by cytochrome P450-derived products of arachidonic acid and other eicosanoids.

Medhora M, Dhanasekaran A, Gruenloh SK, Dunn LK, Gabrilovich M, Falck JR, Harder DR, Jacobs ER, Pratt PF.

Prostaglandins Other Lipid Mediat. 2007 Jan;82(1-4):19-29. Epub 2006 Jul 25. Review.


Protective effects of epoxyeicosatrienoic acids on human endothelial cells from the pulmonary and coronary vasculature.

Dhanasekaran A, Al-Saghir R, Lopez B, Zhu D, Gutterman DD, Jacobs ER, Medhora M.

Am J Physiol Heart Circ Physiol. 2006 Aug;291(2):H517-31. Epub 2006 Apr 14.


Mitochondria superoxide dismutase mimetic inhibits peroxide-induced oxidative damage and apoptosis: role of mitochondrial superoxide.

Dhanasekaran A, Kotamraju S, Karunakaran C, Kalivendi SV, Thomas S, Joseph J, Kalyanaraman B.

Free Radic Biol Med. 2005 Sep 1;39(5):567-83.


Supplementation of endothelial cells with mitochondria-targeted antioxidants inhibit peroxide-induced mitochondrial iron uptake, oxidative damage, and apoptosis.

Dhanasekaran A, Kotamraju S, Kalivendi SV, Matsunaga T, Shang T, Keszler A, Joseph J, Kalyanaraman B.

J Biol Chem. 2004 Sep 3;279(36):37575-87. Epub 2004 Jun 25.


Ceramide-induced intracellular oxidant formation, iron signaling, and apoptosis in endothelial cells: protective role of endogenous nitric oxide.

Matsunaga T, Kotamraju S, Kalivendi SV, Dhanasekaran A, Joseph J, Kalyanaraman B.

J Biol Chem. 2004 Jul 2;279(27):28614-24. Epub 2004 Apr 21.

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