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Items: 38


Rare giant maxillay mucocele: A rare case report and literature review.

Shahi S, Devkota A, Bhandari TR, Pantha T, Gautam D.

Ann Med Surg (Lond). 2019 Jun 1;43:68-71. doi: 10.1016/j.amsu.2019.05.013. eCollection 2019 Jul.


Developing Colorimetric and Luminescence-Based High-Throughput Screening Platforms for Monitoring the GTPase Activity of Ferrous Iron Transport Protein B (FeoB).

Veloria J, Shin M, Devkota AK, Payne SM, Cho EJ, Dalby KN.

SLAS Discov. 2019 Jun;24(5):597-605. doi: 10.1177/2472555219844572. Epub 2019 Apr 30.


Development of a High-Throughput Lysyl Hydroxylase (LH) Assay and Identification of Small-Molecule Inhibitors against LH2.

Devkota AK, Veloria JR, Guo HF, Kurie JM, Cho EJ, Dalby KN.

SLAS Discov. 2019 Apr;24(4):484-491. doi: 10.1177/2472555218817057. Epub 2018 Dec 27.


Tumor deposit is an independent prognostic indicator in patients who underwent radical resection for colorectal cancer.

Basnet S, Lou QF, Liu N, Rana R, Shah A, Khadka M, Warrier H, Sigdel S, Dhakal S, Devkota A, Mishra R, Sapkota G, Zheng L, Ge HY.

J Cancer. 2018 Oct 10;9(21):3979-3985. doi: 10.7150/jca.27475. eCollection 2018.


Excision of rare carotid body tumour without preembolisation: Case report and literature review.

Shahi S, Upadhyay AR, Devkota A, Pantha T, Gautam D, Paudel DR.

Int J Surg Case Rep. 2018;53:99-101. doi: 10.1016/j.ijscr.2018.10.029. Epub 2018 Oct 25.


Community perception and prioritization of invasive alien plants in Chitwan-Annapurna Landscape, Nepal.

Shrestha BB, Shrestha UB, Sharma KP, Thapa-Parajuli RB, Devkota A, Siwakoti M.

J Environ Manage. 2019 Jan 1;229:38-47. doi: 10.1016/j.jenvman.2018.06.034. Epub 2018 Jul 19.


Price Variation and Availability of Free Medicine for Non-communicable Diseases.

Devkota A, Paudel A, Koirala B, Baral D, Gautam S, Sharma SK.

J Nepal Health Res Counc. 2018 Jul 3;16(2):118-123.


Development of a cost effective and robust AlphaScreen® platform for application.

Veloria JR, Devkota AK, Cho EJ, Dalby KN.

Biotechniques. 2018 Apr;64(4):181-183. doi: 10.2144/btn-2018-2001.


Serotonin Analogues as Inhibitors of Breast Cancer Cell Growth.

Jose J, Tavares CDJ, Ebelt ND, Lodi A, Edupuganti R, Xie X, Devkota AK, Kaoud TS, Van Den Berg CL, Anslyn EV, Tiziani S, Bartholomeusz C, Dalby KN.

ACS Med Chem Lett. 2017 Sep 14;8(10):1072-1076. doi: 10.1021/acsmedchemlett.7b00282. eCollection 2017 Oct 12.


A Fluorescence-Based High-Throughput Assay for the Identification of Anticancer Reagents Targeting Fructose-1,6-Bisphosphate Aldolase.

Cho EJ, Devkota AK, Stancu G, Edupunganti R, Powis G, Dalby KN.

SLAS Discov. 2018 Jan;23(1):1-10. doi: 10.1177/2472555217726325. Epub 2017 Aug 18.


A scalable lysyl hydroxylase 2 expression system and luciferase-based enzymatic activity assay.

Guo HF, Cho EJ, Devkota AK, Chen Y, Russell W, Phillips GN Jr, Yamauchi M, Dalby KN, Kurie JM.

Arch Biochem Biophys. 2017 Mar 15;618:45-51. doi: 10.1016/ Epub 2017 Feb 20.


Optimization of a Luminescence-Based High-Throughput Screening Assay for Detecting Apyrase Activity.

Veloria JR, Devkota AK, Cho EJ, Dalby KN.

SLAS Discov. 2017 Jan;22(1):94-101. doi: 10.1177/1087057116675859. Epub 2016 Nov 10.


Definition of a Novel Feed-Forward Mechanism for Glycolysis-HIF1α Signaling in Hypoxic Tumors Highlights Aldolase A as a Therapeutic Target.

Grandjean G, de Jong PR, James B, Koh MY, Lemos R, Kingston J, Aleshin A, Bankston LA, Miller CP, Cho EJ, Edupuganti R, Devkota A, Stancu G, Liddington RC, Dalby K, Powis G.

Cancer Res. 2016 Jul 15;76(14):4259-4269. doi: 10.1158/0008-5472.CAN-16-0401. Epub 2016 Jun 3.


Arrhythmias and Electrocardiographic Changes in Systolic Heart Failure.

Devkota A, Bakhit A, Dufresne A, Oo AN, Parajuli P, Manhas S.

N Am J Med Sci. 2016 Apr;8(4):171-4. doi: 10.4103/1947-2714.179931.


Fostamatinib, an oral spleen tyrosine kinase inhibitor, in the treatment of rheumatoid arthritis: a meta-analysis of randomized controlled trials.

Kunwar S, Devkota AR, Ghimire DK.

Rheumatol Int. 2016 Aug;36(8):1077-87. doi: 10.1007/s00296-016-3482-7. Epub 2016 Apr 25.


Longitudinal tracking of subpopulation dynamics and molecular changes during LNCaP cell castration and identification of inhibitors that could target the PSA-/lo castration-resistant cells.

Rycaj K, Cho EJ, Liu X, Chao HP, Liu B, Li Q, Devkota AK, Zhang D, Chen X, Moore J, Dalby KN, Tang DG.

Oncotarget. 2016 Mar 22;7(12):14220-40. doi: 10.18632/oncotarget.7303.


Application of Eukaryotic Elongation Factor-2 Kinase (eEF-2K) for Cancer Therapy: Expression, Purification, and High-Throughput Inhibitor Screening.

Tavares CD, Devkota AK, Dalby KN, Cho EJ.

Methods Mol Biol. 2016;1360:19-33. doi: 10.1007/978-1-4939-3073-9_2.


A case of chylothorax in a patient with sarcoidosis: a rare and potentially fatal complication.

Bhattarai B, Schmidt F, Devkota A, Policard G, Manhas S, Oke V, Agu CC, Basunia MR, Enriquez D, Quist J, Kharel P.

J Community Hosp Intern Med Perspect. 2015 Sep 1;5(4):28300. doi: 10.3402/jchimp.v5.28300. eCollection 2015.


Reversible covalent inhibition of eEF-2K by carbonitriles.

Devkota AK, Edupuganti R, Yan C, Shi Y, Jose J, Wang Q, Kaoud TS, Cho EJ, Ren P, Dalby KN.

Chembiochem. 2014 Nov 3;15(16):2435-42. doi: 10.1002/cbic.201402321. Epub 2014 Sep 15.


Identification and validation of novel PERK inhibitors.

Wang Q, Park J, Devkota AK, Cho EJ, Dalby KN, Ren P.

J Chem Inf Model. 2014 May 27;54(5):1467-75. doi: 10.1021/ci500114r. Epub 2014 May 5.


Health governance at local level from human resource for health perspectives: the case of Nepal.

Devkota B, Ghimire J, Devkota A, Gupta RP, Mahato RK, Thapa N, Shrestha B, Tuladhar P.

J Nepal Health Res Counc. 2013 May;11(24):133-7.


Involving diaspora and expatriates as human resources in the health sector in Nepal.

Devkota A, Devkota B, Ghimire J, Mahato RK, Gupta RP, Hada A.

J Nepal Health Res Counc. 2013 May;11(24):119-25.


High-throughput screens for eEF-2 kinase.

Devkota AK, Warthaka M, Edupuganti R, Tavares CD, Johnson WH, Ozpolat B, Cho EJ, Dalby KN.

J Biomol Screen. 2014 Mar;19(3):445-52. doi: 10.1177/1087057113505204. Epub 2013 Sep 27.


From in Silico Discovery to intra-Cellular Activity: Targeting JNK-Protein Interactions with Small Molecules.

Kaoud TS, Yan C, Mitra S, Tseng CC, Jose J, Taliaferro JM, Tuohetahuntila M, Devkota A, Sammons R, Park J, Park H, Shi Y, Hong J, Ren P, Dalby KN.

ACS Med Chem Lett. 2012 Aug 6;3(9):721-725.


Investigating the kinetic mechanism of inhibition of elongation factor 2 kinase by NH125: evidence of a common in vitro artifact.

Devkota AK, Tavares CD, Warthaka M, Abramczyk O, Marshall KD, Kaoud TS, Gorgulu K, Ozpolat B, Dalby KN.

Biochemistry. 2012 Mar 13;51(10):2100-12. doi: 10.1021/bi201787p. Epub 2012 Mar 5.


Calcium/calmodulin stimulates the autophosphorylation of elongation factor 2 kinase on Thr-348 and Ser-500 to regulate its activity and calcium dependence.

Tavares CD, O'Brien JP, Abramczyk O, Devkota AK, Shores KS, Ferguson SB, Kaoud TS, Warthaka M, Marshall KD, Keller KM, Zhang Y, Brodbelt JS, Ozpolat B, Dalby KN.

Biochemistry. 2012 Mar 20;51(11):2232-45. doi: 10.1021/bi201788e. Epub 2012 Mar 6.


Purification and characterization of tagless recombinant human elongation factor 2 kinase (eEF-2K) expressed in Escherichia coli.

Abramczyk O, Tavares CD, Devkota AK, Ryazanov AG, Turk BE, Riggs AF, Ozpolat B, Dalby KN.

Protein Expr Purif. 2011 Oct;79(2):237-44. doi: 10.1016/j.pep.2011.05.005. Epub 2011 May 14. Erratum in: Protein Expr Purif. 2012 Oct;85(2):250.


Activated ERK2 is a monomer in vitro with or without divalent cations and when complexed to the cytoplasmic scaffold PEA-15.

Kaoud TS, Devkota AK, Harris R, Rana MS, Abramczyk O, Warthaka M, Lee S, Girvin ME, Riggs AF, Dalby KN.

Biochemistry. 2011 May 31;50(21):4568-78. doi: 10.1021/bi200202y. Epub 2011 May 4.


Solution NMR insights into docking interactions involving inactive ERK2.

Piserchio A, Warthaka M, Devkota AK, Kaoud TS, Lee S, Abramczyk O, Ren P, Dalby KN, Ghose R.

Biochemistry. 2011 May 10;50(18):3660-72. doi: 10.1021/bi2000559. Epub 2011 Apr 19.


Fluorescent peptide assays for protein kinases.

Devkota AK, Kaoud TS, Warthaka M, Dalby KN.

Curr Protoc Mol Biol. 2010 Jul;Chapter 18:Unit 18.17. doi: 10.1002/0471142727.mb1817s91.


Prostaglandin E(2), collagenase, and cell death responses depend on cyclical load magnitude in an explant model of tendinopathy.

Devkota AC, Weinhold PS.

Connect Tissue Res. 2010 Aug;51(4):306-13. doi: 10.3109/03008200903318261.


Distributing a fixed amount of cyclic loading to tendon explants over longer periods induces greater cellular and mechanical responses.

Devkota AC, Tsuzaki M, Almekinders LC, Banes AJ, Weinhold PS.

J Orthop Res. 2007 Aug;25(8):1078-86.


Hepatotoxicity potential of saw palmetto (Serenoa repens) in rats.

Singh YN, Devkota AK, Sneeden DC, Singh KK, Halaweish F.

Phytomedicine. 2007 Feb;14(2-3):204-8. Epub 2006 Jul 18.


Cyclic loading alters biomechanical properties and secretion of PGE2 and NO from tendon explants.

Flick J, Devkota A, Tsuzaki M, Almekinders L, Weinhold P.

Clin Biomech (Bristol, Avon). 2006 Jan;21(1):99-106. Epub 2005 Sep 27.


A tissue explant system for assessing tendon overuse injury.

Devkota AC, Weinhold PS.

Med Eng Phys. 2005 Nov;27(9):803-8.


Thermal microdebridement does not affect the time zero biomechanical properties of human patellar tendons.

Silver WP, Creighton RA, Triantafillopoulos IK, Devkota AC, Weinhold PS, Karas SG.

Am J Sports Med. 2004 Dec;32(8):1946-52.


Mechanical response of tendon subsequent to ramp loading to varying strain limits.

Devkota AC, Weinhold PS.

Clin Biomech (Bristol, Avon). 2003 Dec;18(10):969-74.


Aqueous kava extracts do not affect liver function tests in rats.

Singh YN, Devkota AK.

Planta Med. 2003 Jun;69(6):496-9.


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