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Everolimus for epilepsy in paediatric tuberous sclerosis complex.

Devinsky O.

Lancet Child Adolesc Health. 2018 Jul;2(7):467-469. doi: 10.1016/S2352-4642(18)30128-7. Epub 2018 May 24. No abstract available.


Sudden unexplained death in children.

Crandall L, Devinsky O.

Lancet Child Adolesc Health. 2017 Sep;1(1):8-9. doi: 10.1016/S2352-4642(17)30003-2. Epub 2017 Jul 29. No abstract available.


Dead in the water: Epilepsy-related drowning or sudden unexpected death in epilepsy?

Cihan E, Hesdorffer DC, Brandsoy M, Li L, Fowler DR, Graham JK, Donner EJ, Devinsky O, Friedman D.

Epilepsia. 2018 Aug 26. doi: 10.1111/epi.14546. [Epub ahead of print]


Neural progenitors derived from Tuberous Sclerosis Complex patients exhibit attenuated PI3K/AKT signaling and delayed neuronal differentiation.

Zucco AJ, Pozzo VD, Afinogenova A, Hart RP, Devinsky O, D'Arcangelo G.

Mol Cell Neurosci. 2018 Aug 23;92:149-163. doi: 10.1016/j.mcn.2018.08.004. [Epub ahead of print]


Not all predictions are equal: 'What' and 'When' predictions modulate activity in auditory cortex through different mechanisms.

Auksztulewicz R, Schwiedrzik CM, Thesen T, Doyle W, Devinsky O, Nobre AC, Schroeder CE, Friston KJ, Melloni L.

J Neurosci. 2018 Aug 24. pii: 0369-18. doi: 10.1523/JNEUROSCI.0369-18.2018. [Epub ahead of print]


Cannabidiol in the Lennox-Gastaut Syndrome.

Devinsky O, Patel AD, VanLandingham KE.

N Engl J Med. 2018 Aug 23;379(8):795. doi: 10.1056/NEJMc1807878. No abstract available.


Dietary Measures to Prevent Sudden Unexpected Death in Epilepsy-Reply.

Devinsky O, Ryvlin P, Friedman D.

JAMA Neurol. 2018 Sep 1;75(9):1156. doi: 10.1001/jamaneurol.2018.2254. No abstract available.


Brainstem network disruption: A pathway to sudden unexplained death in epilepsy?

Mueller SG, Nei M, Bateman LM, Knowlton R, Laxer KD, Friedman D, Devinsky O, Goldman AM.

Hum Brain Mapp. 2018 Aug 10. doi: 10.1002/hbm.24325. [Epub ahead of print]


Under-reporting of sudden unexpected death in epilepsy.

Chen S, Joodi G, Devinsky O, Sadaf MI, Pursell IW, Simpson RJ Jr.

Epileptic Disord. 2018 Aug 1;20(4):270-278. doi: 10.1684/epd.2018.0979.


Time-resolved neural reinstatement and pattern separation during memory decisions in human hippocampus.

Lohnas LJ, Duncan K, Doyle WK, Thesen T, Devinsky O, Davachi L.

Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):E7418-E7427. doi: 10.1073/pnas.1717088115. Epub 2018 Jul 13.


Open-label use of highly purified CBD (Epidiolex®) in patients with CDKL5 deficiency disorder and Aicardi, Dup15q, and Doose syndromes.

Devinsky O, Verducci C, Thiele EA, Laux LC, Patel AD, Filloux F, Szaflarski JP, Wilfong A, Clark GD, Park YD, Seltzer LE, Bebin EM, Flamini R, Wechsler RT, Friedman D.

Epilepsy Behav. 2018 Sep;86:131-137. doi: 10.1016/j.yebeh.2018.05.013. Epub 2018 Jul 11.


Short-term safety of mTOR inhibitors in infants and very young children with tuberous sclerosis complex (TSC): Multicentre clinical experience.

Krueger DA, Capal JK, Curatolo P, Devinsky O, Ess K, Tzadok M, Koenig MK, Narayanan V, Ramos F, Jozwiak S, de Vries P, Jansen AC, Wong M, Mowat D, Lawson J, Bruns S, Franz DN; TSCure Research Group.

Eur J Paediatr Neurol. 2018 Jul 4. pii: S1090-3798(17)31969-4. doi: 10.1016/j.ejpn.2018.06.007. [Epub ahead of print]


Long-term safety and treatment effects of cannabidiol in children and adults with treatment-resistant epilepsies: Expanded access program results.

Szaflarski JP, Bebin EM, Comi AM, Patel AD, Joshi C, Checketts D, Beal JC, Laux LC, De Boer LM, Wong MH, Lopez M, Devinsky O, Lyons PD, Zentil PP, Wechsler R; CBD EAP study group.

Epilepsia. 2018 Aug;59(8):1540-1548. doi: 10.1111/epi.14477. Epub 2018 Jul 12.


Incidence of cardiac fibrosis in SUDEP and control cases.

Devinsky O, Kim A, Friedman D, Bedigian A, Moffatt E, Tseng ZH.

Neurology. 2018 Jul 3;91(1):e55-e61. doi: 10.1212/WNL.0000000000005740. Epub 2018 Jun 1.


Resolving ambiguities in SUDEP classification.

Devinsky O, Bundock E, Hesdorffer D, Donner E, Moseley B, Cihan E, Hussain F, Friedman D.

Epilepsia. 2018 Jun;59(6):1220-1233. doi: 10.1111/epi.14195. Epub 2018 May 23.


Serum serotonin levels in patients with epileptic seizures.

Murugesan A, Rani MRS, Hampson J, Zonjy B, Lacuey N, Faingold CL, Friedman D, Devinsky O, Sainju RK, Schuele S, Diehl B, Nei M, Harper RM, Bateman LM, Richerson G, Lhatoo SD.

Epilepsia. 2018 Jun;59(6):e91-e97. doi: 10.1111/epi.14198. Epub 2018 May 17.


Effect of Cannabidiol on Drop Seizures in the Lennox-Gastaut Syndrome.

Devinsky O, Patel AD, Cross JH, Villanueva V, Wirrell EC, Privitera M, Greenwood SM, Roberts C, Checketts D, VanLandingham KE, Zuberi SM; GWPCARE3 Study Group.

N Engl J Med. 2018 May 17;378(20):1888-1897. doi: 10.1056/NEJMoa1714631.



Devinsky O, Vezzani A, O'Brien TJ, Jette N, Scheffer IE, de Curtis M, Perucca P.

Nat Rev Dis Primers. 2018 May 3;4:18024. doi: 10.1038/nrdp.2018.24. Review.


Preventing Sudden Unexpected Death in Epilepsy.

Devinsky O, Ryvlin P, Friedman D.

JAMA Neurol. 2018 May 1;75(5):531-532. doi: 10.1001/jamaneurol.2018.0400. No abstract available.


Author response: Wrist sensor reveals sympathetic hyperactivity and hypoventilation before probable SUDEP.

Picard RW, Migliorini M, Caborni C, Onorati F, Regalia G, Friedman D, Devinsky O.

Neurology. 2018 Apr 10;90(15):713. doi: 10.1212/WNL.0000000000005284. No abstract available.


Presurgical depression and anxiety are not associated with worse epilepsy surgery outcome five years postoperatively.

Altalib HH, Berg AT, Cong X, Vickrey BG, Sperling MR, Shinnar S, Langfitt JT, Walczak TS, Bazil CW, Sukumar N, Devinsky O.

Epilepsy Behav. 2018 Jun;83:7-12. doi: 10.1016/j.yebeh.2018.01.040. Epub 2018 Apr 7.


Deaths in Epilepsy: What We Are Missing.

Devinsky O, Singh A, Friedman D.

JAMA Neurol. 2018 Aug 1;75(8):913-915. doi: 10.1001/jamaneurol.2018.0002. No abstract available.


Cardiac arrhythmia and neuroexcitability gene variants in resected brain tissue from patients with sudden unexpected death in epilepsy (SUDEP).

Friedman D, Kannan K, Faustin A, Shroff S, Thomas C, Heguy A, Serrano J, Snuderl M, Devinsky O.

NPJ Genom Med. 2018 Mar 27;3:9. doi: 10.1038/s41525-018-0048-5. eCollection 2018.


Novel bandlike signal abnormality suggestive of heterotopia in patient with a KCNQ1 frameshift mutation.

Sabharwal P, Devinsky O, M Shepherd T.

Epilepsia Open. 2017 Aug 23;2(4):481-484. doi: 10.1002/epi4.12072. eCollection 2017 Dec.


A comprehensive approach to identifying repurposed drugs to treat SCN8A epilepsy.

Atkin TA, Maher CM, Gerlach AC, Gay BC, Antonio BM, Santos SC, Padilla KM, Rader J, Krafte DS, Fox MA, Stewart GR, Petrovski S, Devinsky O, Might M, Petrou S, Goldstein DB.

Epilepsia. 2018 Apr;59(4):802-813. doi: 10.1111/epi.14037. Epub 2018 Mar 25.


Randomized, dose-ranging safety trial of cannabidiol in Dravet syndrome.

Devinsky O, Patel AD, Thiele EA, Wong MH, Appleton R, Harden CL, Greenwood S, Morrison G, Sommerville K; GWPCARE1 Part A Study Group.

Neurology. 2018 Apr 3;90(14):e1204-e1211. doi: 10.1212/WNL.0000000000005254. Epub 2018 Mar 14.


Author response: Underestimation of sudden deaths among patients with seizures and epilepsy.

Devinsky O, Friedman D, Cheng JY, Moffatt E, Kim A, Tseng ZH.

Neurology. 2018 Mar 13;90(11):532. doi: 10.1212/WNL.0000000000005114. No abstract available.


National Association of Medical Examiners position paper: Recommendations for the investigation and certification of deaths in people with epilepsy.

Middleton O, Atherton D, Bundock E, Donner E, Friedman D, Hesdorffer D, Jarrell H, McCrillis A, Mena OJ, Morey M, Thurman D, Tian N, Tomson T, Tseng Z, White S, Wright C, Devinsky O.

Epilepsia. 2018 Mar;59(3):530-543. doi: 10.1111/epi.14030. Epub 2018 Mar 1.


Author Correction: Low frequency transcranial electrical stimulation does not entrain sleep rhythms measured by human intracranial recordings.

Lafon B, Henin S, Huang Y, Friedman D, Melloni L, Thesen T, Doyle W, Buzsáki G, Devinsky O, Parra LC, Liu A.

Nat Commun. 2018 Feb 28;9(1):949. doi: 10.1038/s41467-018-03392-9.


Species-specific susceptibility to cannabis-induced convulsions.

Whalley BJ, Lin H, Bell L, Hill T, Patel A, Gray RA, Elizabeth Roberts C, Devinsky O, Bazelot M, Williams CM, Stephens GJ.

Br J Pharmacol. 2018 Feb 19. doi: 10.1111/bph.14165. [Epub ahead of print]


Functional brain connectivity is predictable from anatomic network's Laplacian eigen-structure.

Abdelnour F, Dayan M, Devinsky O, Thesen T, Raj A.

Neuroimage. 2018 May 15;172:728-739. doi: 10.1016/j.neuroimage.2018.02.016. Epub 2018 Feb 14.


Heterogeneous Origins of Human Sleep Spindles in Different Cortical Layers.

Hagler DJ Jr, Ulbert I, Wittner L, Erőss L, Madsen JR, Devinsky O, Doyle W, Fabó D, Cash SS, Halgren E.

J Neurosci. 2018 Mar 21;38(12):3013-3025. doi: 10.1523/JNEUROSCI.2241-17.2018. Epub 2018 Feb 15.


Correction: Measurements and models of electric fields in the in vivo human brain during transcranial electric stimulation.

Huang Y, Liu AA, Lafon B, Friedman D, Dayan M, Wang X, Bikson M, Doyle WK, Devinsky O, Parra LC.

Elife. 2018 Feb 15;7. pii: e35178. doi: 10.7554/eLife.35178. No abstract available.


Superficial Slow Rhythms Integrate Cortical Processing in Humans.

Halgren M, Fabó D, Ulbert I, Madsen JR, Erőss L, Doyle WK, Devinsky O, Schomer D, Cash SS, Halgren E.

Sci Rep. 2018 Feb 1;8(1):2055. doi: 10.1038/s41598-018-20662-0.


Structural brain abnormalities in the common epilepsies assessed in a worldwide ENIGMA study.

Whelan CD, Altmann A, Botía JA, Jahanshad N, Hibar DP, Absil J, Alhusaini S, Alvim MKM, Auvinen P, Bartolini E, Bergo FPG, Bernardes T, Blackmon K, Braga B, Caligiuri ME, Calvo A, Carr SJ, Chen J, Chen S, Cherubini A, David P, Domin M, Foley S, França W, Haaker G, Isaev D, Keller SS, Kotikalapudi R, Kowalczyk MA, Kuzniecky R, Langner S, Lenge M, Leyden KM, Liu M, Loi RQ, Martin P, Mascalchi M, Morita ME, Pariente JC, Rodríguez-Cruces R, Rummel C, Saavalainen T, Semmelroch MK, Severino M, Thomas RH, Tondelli M, Tortora D, Vaudano AE, Vivash L, von Podewils F, Wagner J, Weber B, Yao Y, Yasuda CL, Zhang G, Bargalló N, Bender B, Bernasconi N, Bernasconi A, Bernhardt BC, Blümcke I, Carlson C, Cavalleri GL, Cendes F, Concha L, Delanty N, Depondt C, Devinsky O, Doherty CP, Focke NK, Gambardella A, Guerrini R, Hamandi K, Jackson GD, Kälviäinen R, Kochunov P, Kwan P, Labate A, McDonald CR, Meletti S, O'Brien TJ, Ourselin S, Richardson MP, Striano P, Thesen T, Wiest R, Zhang J, Vezzani A, Ryten M, Thompson PM, Sisodiya SM.

Brain. 2018 Feb 1;141(2):391-408. doi: 10.1093/brain/awx341.


The incidence and significance of periictal apnea in epileptic seizures.

Lacuey N, Zonjy B, Hampson JP, Rani MRS, Zaremba A, Sainju RK, Gehlbach BK, Schuele S, Friedman D, Devinsky O, Nei M, Harper RM, Allen L, Diehl B, Millichap JJ, Bateman L, Granner MA, Dragon DN, Richerson GB, Lhatoo SD.

Epilepsia. 2018 Mar;59(3):573-582. doi: 10.1111/epi.14006. Epub 2018 Jan 16.


Sudden unexpected death in epilepsy in patients treated with brain-responsive neurostimulation.

Devinsky O, Friedman D, Duckrow RB, Fountain NB, Gwinn RP, Leiphart JW, Murro AM, Van Ness PC.

Epilepsia. 2018 Mar;59(3):555-561. doi: 10.1111/epi.13998. Epub 2018 Jan 16.


Long-term surveillance of SUDEP in drug-resistant epilepsy patients treated with VNS therapy.

Ryvlin P, So EL, Gordon CM, Hesdorffer DC, Sperling MR, Devinsky O, Bunker MT, Olin B, Friedman D.

Epilepsia. 2018 Mar;59(3):562-572. doi: 10.1111/epi.14002. Epub 2018 Jan 16.


Defining the phenotypic spectrum of SLC6A1 mutations.

Johannesen KM, Gardella E, Linnankivi T, Courage C, de Saint Martin A, Lehesjoki AE, Mignot C, Afenjar A, Lesca G, Abi-Warde MT, Chelly J, Piton A, Merritt JL 2nd, Rodan LH, Tan WH, Bird LM, Nespeca M, Gleeson JG, Yoo Y, Choi M, Chae JH, Czapansky-Beilman D, Reichert SC, Pendziwiat M, Verhoeven JS, Schelhaas HJ, Devinsky O, Christensen J, Specchio N, Trivisano M, Weber YG, Nava C, Keren B, Doummar D, Schaefer E, Hopkins S, Dubbs H, Shaw JE, Pisani L, Myers CT, Tang S, Tang S, Pal DK, Millichap JJ, Carvill GL, Helbig KL, Mecarelli O, Striano P, Helbig I, Rubboli G, Mefford HC, Møller RS.

Epilepsia. 2018 Feb;59(2):389-402. doi: 10.1111/epi.13986. Epub 2018 Jan 8.


Applying High-Resolution Variant Classification to Cardiac Arrhythmogenic Gene Testing in a Demographically Diverse Cohort of Sudden Unexplained Deaths.

Lin Y, Williams N, Wang D, Coetzee W, Zhou B, Eng LS, Um SY, Bao R, Devinsky O, McDonald TV, Sampson BA, Tang Y.

Circ Cardiovasc Genet. 2017 Dec;10(6). pii: e001839. doi: 10.1161/CIRCGENETICS.117.001839.


Replay of large-scale spatio-temporal patterns from waking during subsequent NREM sleep in human cortex.

Jiang X, Shamie I, K Doyle W, Friedman D, Dugan P, Devinsky O, Eskandar E, Cash SS, Thesen T, Halgren E.

Sci Rep. 2017 Dec 12;7(1):17380. doi: 10.1038/s41598-017-17469-w.


Review: The past, present and future challenges in epilepsy-related and sudden deaths and biobanking.

Thom M, Boldrini M, Bundock E, Sheppard MN, Devinsky O.

Neuropathol Appl Neurobiol. 2018 Feb;44(1):32-55. doi: 10.1111/nan.12453. Review.


Letter re: Practice guideline summary: Sudden unexpected death in epilepsy incidence rates and risk factors: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology and the American Epilepsy Society.

Stanton T, Harding R, Gattone P, Friedman D, Geiger A, Devinsky O, Rosbeck KL, Vogel-Farley V, Meskis MA, Singer A, Miller AB, Miller I.

Neurology. 2017 Nov 21;89(21):2213-2214. doi: 10.1212/WNL.0000000000004660. No abstract available.


Perceptual confidence neglects decision-incongruent evidence in the brain.

Peters MAK, Thesen T, Ko YD, Maniscalco B, Carlson C, Davidson M, Doyle W, Kuzniecky R, Devinsky O, Halgren E, Lau H.

Nat Hum Behav. 2017;1. pii: 0139. doi: 10.1038/s41562-017-0139. Epub 2017 Jul 10. No abstract available.


Low frequency transcranial electrical stimulation does not entrain sleep rhythms measured by human intracranial recordings.

Lafon B, Henin S, Huang Y, Friedman D, Melloni L, Thesen T, Doyle W, Buzsáki G, Devinsky O, Parra LC, A Liu A.

Nat Commun. 2017 Oct 31;8(1):1199. doi: 10.1038/s41467-017-01045-x. Erratum in: Nat Commun. 2018 Feb 28;9(1):949.


Organic electronics for high-resolution electrocorticography of the human brain.

Khodagholy D, Gelinas JN, Zhao Z, Yeh M, Long M, Greenlee JD, Doyle W, Devinsky O, Buzsáki G.

Sci Adv. 2016 Nov 9;2(11):e1601027. doi: 10.1126/sciadv.1601027. eCollection 2016 Nov.


Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome.

Devinsky O, Cross JH, Wright S.

N Engl J Med. 2017 Aug 17;377(7):699-700. doi: 10.1056/NEJMc1708349. No abstract available.


Underestimation of sudden deaths among patients with seizures and epilepsy.

Devinsky O, Friedman D, Cheng JY, Moffatt E, Kim A, Tseng ZH.

Neurology. 2017 Aug 29;89(9):886-892. doi: 10.1212/WNL.0000000000004292. Epub 2017 Aug 2.


Wrist sensor reveals sympathetic hyperactivity and hypoventilation before probable SUDEP.

Picard RW, Migliorini M, Caborni C, Onorati F, Regalia G, Friedman D, Devinsky O.

Neurology. 2017 Aug 8;89(6):633-635. doi: 10.1212/WNL.0000000000004208. Epub 2017 Jul 12. No abstract available.


Mortality with brainstem seizures from focal 4-aminopyridine-induced recurrent hippocampal seizures.

Salam MT, Montandon G, Genov R, Devinsky O, Del Campo M, Carlen PL.

Epilepsia. 2017 Sep;58(9):1637-1644. doi: 10.1111/epi.13846. Epub 2017 Jul 10.

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