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Items: 1 to 50 of 138

1.

Use of Organ Dysfunction as A Primary Outcome Variable Following Cecal Ligation and Puncture: Recommendations for Future Studies.

Abraham MN, Kelly AP, Brandwein AB, Fernandes TD, Leisman DE, Taylor MD, Brewer MR, Capone CA, Deutschman CS.

Shock. 2019 Nov 18. doi: 10.1097/SHK.0000000000001485. [Epub ahead of print]

PMID:
31764625
2.

MITOCHONDRIAL DYSFUNCTION IS ASSOCIATED WITH AN IMMUNE PARALYSIS PHENOTYPE IN PEDIATRIC SEPSIS.

Weiss SL, Zhang D, Bush J, Graham K, Starr J, Murray J, Tuluc F, Henrickson S, Deutschman CS, Becker L, Jr FXM, Wallace DC.

Shock. 2019 Nov 20. doi: 10.1097/SHK.0000000000001486. [Epub ahead of print]

PMID:
31764621
3.

Buprenorphine Markedly Elevates a Panel of Surrogate Markers in a Murine Model of Sepsis.

Chen W, Brenner M, Aziz M, Chavan SS, Deutschman CS, Diamond B, Pavlov VA, Sherry B, Wang P, Tracey KJ, Wang H.

Shock. 2019 Nov;52(5):550-553. doi: 10.1097/SHK.0000000000001361.

4.

Persistent Mitochondrial Dysfunction Linked to Prolonged Organ Dysfunction in Pediatric Sepsis.

Weiss SL, Zhang D, Bush J, Graham K, Starr J, Tuluc F, Henrickson S, Kilbaugh T, Deutschman CS, Murdock D, McGowan FX Jr, Becker L, Wallace DC.

Crit Care Med. 2019 Oct;47(10):1433-1441. doi: 10.1097/CCM.0000000000003931.

PMID:
31385882
5.

Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): An International Expert Consensus Initiative for Improvement of Animal Modeling in Sepsis.

Osuchowski MF, Ayala A, Bahrami S, Bauer M, Boros M, Cavaillon JM, Chaudry IH, Coopersmith CM, Deutschman CS, Drechsler S, Efron P, Frostell C, Fritsch G, Gozdzik W, Hellman J, Huber-Lang M, Inoue S, Knapp S, Kozlov AV, Libert C, Marshall JC, Moldawer LL, Radermacher P, Redl H, Remick DG, Singer M, Thiemermann C, Wang P, Wiersinga WJ, Xiao X, Zingarelli B.

Shock. 2018 Oct;50(4):377-380. doi: 10.1097/SHK.0000000000001212.

6.

Surviving sepsis campaign: research priorities for sepsis and septic shock.

Coopersmith CM, De Backer D, Deutschman CS, Ferrer R, Lat I, Machado FR, Martin GS, Martin-Loeches I, Nunnally ME, Antonelli M, Evans LE, Hellman J, Jog S, Kesecioglu J, Levy MM, Rhodes A.

Intensive Care Med. 2018 Sep;44(9):1400-1426. doi: 10.1007/s00134-018-5175-z. Epub 2018 Jul 3.

PMID:
29971592
7.

Surviving Sepsis Campaign: Research Priorities for Sepsis and Septic Shock.

Coopersmith CM, De Backer D, Deutschman CS, Ferrer R, Lat I, Machado FR, Martin GS, Martin-Loeches I, Nunnally ME, Antonelli M, Evans LE, Hellman J, Jog S, Kesecioglu J, Levy MM, Rhodes A.

Crit Care Med. 2018 Aug;46(8):1334-1356. doi: 10.1097/CCM.0000000000003225.

PMID:
29957716
8.

What is a Clinician to Do?

Deutschman CS.

Crit Care Med. 2018 Jul;46(7):1205-1206. doi: 10.1097/CCM.0000000000003174. No abstract available.

PMID:
29912109
9.

Cecal Ligation and Puncture Alters Glucocorticoid Receptor Expression.

Abraham MN, Jimenez DM, Fernandes TD, Deutschman CS.

Crit Care Med. 2018 Aug;46(8):e797-e804. doi: 10.1097/CCM.0000000000003201.

PMID:
29787416
10.

Translational Research: The Model Matters.

Deutschman CS.

Crit Care Med. 2018 May;46(5):835-837. doi: 10.1097/CCM.0000000000003033. No abstract available.

11.

Are septic children really just "septic little adults"?

Weiss SL, Deutschman CS.

Intensive Care Med. 2018 Mar;44(3):392-394. doi: 10.1007/s00134-017-5041-4. Epub 2018 Jan 22. No abstract available.

PMID:
29356850
12.

Sepsis-3: Seeing the Entire Picture.

Deutschman CS.

Crit Care Med. 2017 Sep;45(9):1567-1569. doi: 10.1097/CCM.0000000000002543. No abstract available.

PMID:
28816841
13.

"Defining" Sepsis: Moving Toward Measuring the "Dysregulated Host Response".

Deutschman CS.

Crit Care Med. 2017 May;45(5):927-930. doi: 10.1097/CCM.0000000000002389. No abstract available.

PMID:
28410317
14.

Sepsis-3: Of Love and Bliss.

Deutschman CS.

Crit Care Med. 2017 Apr;45(4):739-740. doi: 10.1097/CCM.0000000000002248. No abstract available.

PMID:
28291096
15.

The author replies.

Deutschman CS.

Crit Care Med. 2016 Nov;44(11):e1144-e1145. No abstract available.

PMID:
27755084
16.

The New Sepsis Definitions: Implications for the Basic and Translational Research Communities.

Coopersmith CM, Deutschman CS.

Shock. 2017 Mar;47(3):264-268. doi: 10.1097/SHK.0000000000000763.

PMID:
27749763
17.

Composition of the Sepsis Definitions Task Force--Reply.

Deutschman CS, Singer M.

JAMA. 2016 Jul 26;316(4):461-2. doi: 10.1001/jama.2016.6395. No abstract available.

PMID:
27458966
18.

Definitions for Sepsis and Septic Shock--Reply.

Deutschman CS, Singer M.

JAMA. 2016 Jul 26;316(4):458-9. doi: 10.1001/jama.2016.6389. No abstract available.

PMID:
27458962
19.

Imprecise Medicine: The Limitations of Sepsis-3.

Deutschman CS.

Crit Care Med. 2016 May;44(5):857-8. doi: 10.1097/CCM.0000000000001834. No abstract available.

PMID:
27083014
20.

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).

Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, Bellomo R, Bernard GR, Chiche JD, Coopersmith CM, Hotchkiss RS, Levy MM, Marshall JC, Martin GS, Opal SM, Rubenfeld GD, van der Poll T, Vincent JL, Angus DC.

JAMA. 2016 Feb 23;315(8):801-10. doi: 10.1001/jama.2016.0287.

21.

Developing a New Definition and Assessing New Clinical Criteria for Septic Shock: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).

Shankar-Hari M, Phillips GS, Levy ML, Seymour CW, Liu VX, Deutschman CS, Angus DC, Rubenfeld GD, Singer M; Sepsis Definitions Task Force.

JAMA. 2016 Feb 23;315(8):775-87. doi: 10.1001/jama.2016.0289. Review.

22.

Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).

Seymour CW, Liu VX, Iwashyna TJ, Brunkhorst FM, Rea TD, Scherag A, Rubenfeld G, Kahn JM, Shankar-Hari M, Singer M, Deutschman CS, Escobar GJ, Angus DC.

JAMA. 2016 Feb 23;315(8):762-74. doi: 10.1001/jama.2016.0288. Erratum in: JAMA. 2016 May 24-31;315(20):2237.

23.

Application of a Framework to Assess the Usefulness of Alternative Sepsis Criteria.

Seymour CW, Coopersmith CM, Deutschman CS, Gesten F, Klompas M, Levy M, Martin GS, Osborn TM, Rhee C, Warren DK, Watson RS, Angus DC.

Crit Care Med. 2016 Mar;44(3):e122-30. doi: 10.1097/CCM.0000000000001724.

24.

A Framework for the Development and Interpretation of Different Sepsis Definitions and Clinical Criteria.

Angus DC, Seymour CW, Coopersmith CM, Deutschman CS, Klompas M, Levy MM, Martin GS, Osborn TM, Rhee C, Watson RS.

Crit Care Med. 2016 Mar;44(3):e113-21. doi: 10.1097/CCM.0000000000001730. Review.

25.

MITOCHONDRIAL FUNCTION IN SEPSIS.

Arulkumaran N, Deutschman CS, Pinsky MR, Zuckerbraun B, Schumacker PT, Gomez H, Gomez A, Murray P, Kellum JA; ADQI XIV Workgroup.

Shock. 2016 Mar;45(3):271-81. doi: 10.1097/SHK.0000000000000463. Review.

26.

Judging quality of current septic shock definitions and criteria.

Shankar-Hari M, Bertolini G, Brunkhorst FM, Bellomo R, Annane D, Deutschman CS, Singer M.

Crit Care. 2015 Dec 25;19:445. doi: 10.1186/s13054-015-1164-6.

27.

TAT-HSP70 Attenuates Experimental Lung Injury.

Lyons MM, Raj NN, Chittams JL, Kilpatrick L, Deutschman CS.

Shock. 2015 Jun;43(6):582-8. doi: 10.1097/SHK.0000000000000352.

28.

Do we need a new definition of sepsis?

Shankar-Hari M, Deutschman CS, Singer M.

Intensive Care Med. 2015 May;41(5):909-11. doi: 10.1007/s00134-015-3680-x. Epub 2015 Feb 3. No abstract available.

PMID:
25643905
29.

Choosing wisely(®) in critical care: maximizing value in the intensive care unit.

Angus DC, Deutschman CS, Hall JB, Wilson KC, Munro CL, Hill NS.

Am J Crit Care. 2014 Nov;23(6):444-6. doi: 10.4037/ajcc2014481. No abstract available.

PMID:
25362666
30.

Choosing wisely® in critical care: maximizing value in the intensive care unit.

Angus DC, Deutschman CS, Hall JB, Wilson KC, Munro CL, Hill NS.

Crit Care Med. 2014 Nov;42(11):2437-8. doi: 10.1097/CCM.0000000000000696. No abstract available.

PMID:
25319903
31.

Choosing wisely in critical care: maximizing value in the ICU.

Angus DC, Deutschman CS, Hall JB, Wilson KC, Munro CL, Hill NS.

Chest. 2014 Nov;146(5):1142-1144. doi: 10.1378/chest.14-0912. Review. No abstract available.

PMID:
25317583
32.

Mitochondrial dysfunction in peripheral blood mononuclear cells in pediatric septic shock.

Weiss SL, Selak MA, Tuluc F, Perales Villarroel J, Nadkarni VM, Deutschman CS, Becker LB.

Pediatr Crit Care Med. 2015 Jan;16(1):e4-e12. doi: 10.1097/PCC.0000000000000277.

33.

Elevated malondialdehyde levels in sepsis - something to 'stress' about?

Weiss SL, Deutschman CS.

Crit Care. 2014 Mar 19;18(2):125. doi: 10.1186/cc13786.

34.

Sepsis: current dogma and new perspectives.

Deutschman CS, Tracey KJ.

Immunity. 2014 Apr 17;40(4):463-75. doi: 10.1016/j.immuni.2014.04.001. Review.

35.

Executive summary: Developing a new, national approach to surveillance for ventilator-associated events.

Magill SS, Klompas M, Balk R, Burns SM, Deutschman CS, Diekema D, Fridkin S, Greene L, Guh A, Gutterman D, Hammer B, Henderson D, Hess DR, Hill NS, Horan T, Kollef M, Levy M, Septimus E, Vanantwerpen C, Wright D, Lipsett P.

Ann Am Thorac Soc. 2013 Dec;10(6):S220-3. doi: 10.1513/AnnalsATS.201309-314OT. No abstract available.

PMID:
24364784
36.

Developing a new, national approach to surveillance for ventilator-associated events: executive summary.

Magill SS, Klompas M, Balk R, Burns SM, Deutschman CS, Diekema D, Fridkin S, Greene L, Guh A, Gutterman D, Hammer B, Henderson D, Hess D, Hill NS, Horan T, Kollef M, Levy M, Septimus E, Vanantwerpen C, Wright D, Lipsett P.

Clin Infect Dis. 2013 Dec;57(12):1742-6. doi: 10.1093/cid/cit577. No abstract available.

37.

Developing a new, national approach to surveillance for ventilator-associated events: executive summary.

Magill SS, Klompas M, Balk R, Burns SM, Deutschman CS, Diekema D, Fridkin S, Greene L, Guh A, Gutterman D, Hammer B, Henderson D, Hess DR, Hill NS, Horan T, Kollef M, Levy M, Septimus E, Vanantwerpen C, Wright D, Lipsett P.

Infect Control Hosp Epidemiol. 2013 Dec;34(12):1239-43. doi: 10.1086/673463. Epub 2013 Oct 24. No abstract available.

PMID:
24225607
38.

Developing a new, national approach to surveillance for ventilator-associated events: executive summary.

Magill SS, Klompas M, Balk R, Burns SM, Deutschman CS, Diekema D, Fridkin S, Greene L, Guh A, Gutterman D, Hammer B, Henderson D, Hess DR, Hill NS, Horan T, Kollef M, Levy M, Septimus E, VanAntwerpen C, Wright D, Lipsett P.

Chest. 2013 Nov;144(5):1448-1452. doi: 10.1378/chest.13-1640. No abstract available.

39.

Developing a new, national approach to surveillance for ventilator-associated events.

Magill SS, Klompas M, Balk R, Burns SM, Deutschman CS, Diekema D, Fridkin S, Greene L, Guh A, Gutterman D, Hammer B, Henderson D, Hess DR, Hill NS, Horan T, Kollef M, Levy M, Septimus E, Vanantwerpen C, Wright D, Lipsett P.

Am J Crit Care. 2013 Nov;22(6):469-73. doi: 10.4037/ajcc2013893.

PMID:
24186816
40.

Developing a new national approach to surveillance for ventilator-associated events: executive summary.

Magill SS, Klompas M, Balk R, Burns SM, Deutschman CS, Diekema D, Fridkin S, Greene L, Guh A, Gutterman D, Hammer B, Henderson D, Hess DR, Hill NS, Horan T, Kollef M, Levy M, Septimus E, VanAntwerpen C, Wright D, Lipsett P.

Am J Infect Control. 2013 Nov;41(11):1096-9. doi: 10.1016/j.ajic.2013.07.001.

PMID:
24176770
41.

Developing a new, national approach to surveillance for ventilator-associated events*.

Magill SS, Klompas M, Balk R, Burns SM, Deutschman CS, Diekema D, Fridkin S, Greene L, Guh A, Gutterman D, Hammer B, Henderson D, Hess D, Hill NS, Horan T, Kollef M, Levy M, Septimus E, VanAntwerpen C, Wright D, Lipsett P.

Crit Care Med. 2013 Nov;41(11):2467-75. doi: 10.1097/CCM.0b013e3182a262db.

PMID:
24162674
42.

Therapy for sepsis: Einstein once said...

Deutschman CS.

Br J Anaesth. 2013 Nov;111(5):693-5. doi: 10.1093/bja/aet157. No abstract available.

43.

Orexinergic activity modulates altered vital signs and pituitary hormone secretion in experimental sepsis.

Deutschman CS, Raj NR, McGuire EO, Kelz MB.

Crit Care Med. 2013 Nov;41(11):e368-75. doi: 10.1097/CCM.0b013e31828e9843.

44.

Positive end-expiratory pressure increments during anesthesia in normal lung result in hysteresis and greater numbers of smaller aerated airspaces.

Cereda M, Xin Y, Emami K, Huang J, Rajaei J, Profka H, Han B, Mongkolwisetwara P, Kadlecek S, Kuzma NN, Pickup S, Kavanagh BP, Deutschman CS, Rizi RR.

Anesthesiology. 2013 Dec;119(6):1402-9. doi: 10.1097/ALN.0b013e3182a9b0c1.

45.

Steroid responses in sepsis: some novel thinking that may provide new insight.

Deutschman CS.

Crit Care. 2013 Jun 27;17(3):147. doi: 10.1186/cc12723.

46.

Protein kinase C and acute respiratory distress syndrome.

Mondrinos MJ, Kennedy PA, Lyons M, Deutschman CS, Kilpatrick LE.

Shock. 2013 Jun;39(6):467-79. doi: 10.1097/SHK.0b013e318294f85a. Review.

47.

Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012.

Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, Osborn TM, Nunnally ME, Townsend SR, Reinhart K, Kleinpell RM, Angus DC, Deutschman CS, Machado FR, Rubenfeld GD, Webb S, Beale RJ, Vincent JL, Moreno R; Surviving Sepsis Campaign Guidelines Committee including The Pediatric Subgroup.

Intensive Care Med. 2013 Feb;39(2):165-228. doi: 10.1007/s00134-012-2769-8. Epub 2013 Jan 30.

PMID:
23361625
48.

Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012.

Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, Osborn TM, Nunnally ME, Townsend SR, Reinhart K, Kleinpell RM, Angus DC, Deutschman CS, Machado FR, Rubenfeld GD, Webb SA, Beale RJ, Vincent JL, Moreno R; Surviving Sepsis Campaign Guidelines Committee including the Pediatric Subgroup.

Crit Care Med. 2013 Feb;41(2):580-637. doi: 10.1097/CCM.0b013e31827e83af.

PMID:
23353941
49.

Imaging the interaction of atelectasis and overdistension in surfactant-depleted lungs.

Cereda M, Emami K, Xin Y, Kadlecek S, Kuzma NN, Mongkolwisetwara P, Profka H, Pickup S, Ishii M, Kavanagh BP, Deutschman CS, Rizi RR.

Crit Care Med. 2013 Feb;41(2):527-35. doi: 10.1097/CCM.0b013e31826ab1f2.

50.

Multisociety task force for critical care research: key issues and recommendations.

Deutschman CS, Ahrens T, Cairns CB, Sessler CN, Parsons PE; Critical Care Societies Collaborative/USCIITG Task Force on Critical Care Research.

Crit Care Nurse. 2012 Feb;32(1):16-8. doi: 10.4037/ajcc2012608. No abstract available.

PMID:
22298714

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