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Items: 1 to 50 of 215

1.

RNase II regulates RNase PH and is essential for cell survival during starvation and stationary phase.

Sulthana S, Quesada E, Deutscher MP.

RNA. 2017 Sep;23(9):1456-1464. doi: 10.1261/rna.060558.116. Epub 2017 Jun 16.

2.

Growth Phase-dependent Variation of RNase BN/Z Affects Small RNAs: REGULATION OF 6S RNA.

Chen H, Dutta T, Deutscher MP.

J Biol Chem. 2016 Dec 16;291(51):26435-26442. Epub 2016 Nov 8.

3.

Elucidation of pathways of ribosomal RNA degradation: an essential role for RNase E.

Sulthana S, Basturea GN, Deutscher MP.

RNA. 2016 Aug;22(8):1163-71. doi: 10.1261/rna.056275.116. Epub 2016 Jun 13.

4.

Helicase Activity Plays a Crucial Role for RNase R Function in Vivo and for RNA Metabolism.

Hossain ST, Deutscher MP.

J Biol Chem. 2016 Apr 29;291(18):9438-43. doi: 10.1074/jbc.C116.726091. Epub 2016 Mar 28.

5.

How RNase R Degrades Structured RNA: ROLE OF THE HELICASE ACTIVITY AND THE S1 DOMAIN.

Hossain ST, Malhotra A, Deutscher MP.

J Biol Chem. 2016 Apr 8;291(15):7877-87. doi: 10.1074/jbc.M116.717991. Epub 2016 Feb 12.

6.

Reversible acetylation on Lys501 regulates the activity of RNase II.

Song L, Wang G, Malhotra A, Deutscher MP, Liang W.

Nucleic Acids Res. 2016 Mar 18;44(5):1979-88. doi: 10.1093/nar/gkw053. Epub 2016 Feb 4.

7.

REP sequences: Mediators of the environmental stress response?

Liang W, Deutscher MP.

RNA Biol. 2016;13(2):152-6. doi: 10.1080/15476286.2015.1112489. Epub 2015 Nov 17.

8.

The Helicase Activity of Ribonuclease R Is Essential for Efficient Nuclease Activity.

Hossain ST, Malhotra A, Deutscher MP.

J Biol Chem. 2015 Jun 19;290(25):15697-706. doi: 10.1074/jbc.M115.650176. Epub 2015 Apr 30.

9.

A role for REP sequences in regulating translation.

Liang W, Rudd KE, Deutscher MP.

Mol Cell. 2015 May 7;58(3):431-9. doi: 10.1016/j.molcel.2015.03.019. Epub 2015 Apr 16.

10.

How bacterial cells keep ribonucleases under control.

Deutscher MP.

FEMS Microbiol Rev. 2015 May;39(3):350-61. doi: 10.1093/femsre/fuv012. Epub 2015 Apr 14. Review.

11.

Human DNA Exonuclease TREX1 Is Also an Exoribonuclease That Acts on Single-stranded RNA.

Yuan F, Dutta T, Wang L, Song L, Gu L, Qian L, Benitez A, Ning S, Malhotra A, Deutscher MP, Zhang Y.

J Biol Chem. 2015 May 22;290(21):13344-53. doi: 10.1074/jbc.M115.653915. Epub 2015 Apr 8.

12.

Twenty years of bacterial RNases and RNA processing: how we've matured.

Deutscher MP.

RNA. 2015 Apr;21(4):597-600. doi: 10.1261/rna.049692.115. No abstract available.

13.

Ribosomes regulate the stability and action of the exoribonuclease RNase R.

Liang W, Deutscher MP.

J Biol Chem. 2013 Nov 29;288(48):34791-8. doi: 10.1074/jbc.M113.519553. Epub 2013 Oct 16.

14.

How a CCA sequence protects mature tRNAs and tRNA precursors from action of the processing enzyme RNase BN/RNase Z.

Dutta T, Malhotra A, Deutscher MP.

J Biol Chem. 2013 Oct 18;288(42):30636-44. doi: 10.1074/jbc.M113.514570. Epub 2013 Sep 10.

15.

Multiple exoribonucleases catalyze maturation of the 3' terminus of 16S ribosomal RNA (rRNA).

Sulthana S, Deutscher MP.

J Biol Chem. 2013 May 3;288(18):12574-9. doi: 10.1074/jbc.C113.459172. Epub 2013 Mar 26.

16.

Exoribonuclease and endoribonuclease activities of RNase BN/RNase Z both function in vivo.

Dutta T, Malhotra A, Deutscher MP.

J Biol Chem. 2012 Oct 12;287(42):35747-55. doi: 10.1074/jbc.M112.407403. Epub 2012 Aug 14.

17.
18.

Growth of a bacterium that apparently uses arsenic instead of phosphorus is a consequence of massive ribosome breakdown.

Basturea GN, Harris TK, Deutscher MP.

J Biol Chem. 2012 Aug 17;287(34):28816-9. doi: 10.1074/jbc.C112.394403. Epub 2012 Jul 13.

19.

The structure and enzymatic properties of a novel RNase II family enzyme from Deinococcus radiodurans.

Schmier BJ, Seetharaman J, Deutscher MP, Hunt JF, Malhotra A.

J Mol Biol. 2012 Jan 20;415(3):547-59. doi: 10.1016/j.jmb.2011.11.031. Epub 2011 Nov 23.

20.

Post-translational modification of RNase R is regulated by stress-dependent reduction in the acetylating enzyme Pka (YfiQ).

Liang W, Deutscher MP.

RNA. 2012 Jan;18(1):37-41. doi: 10.1261/rna.030213.111. Epub 2011 Nov 28.

21.

YhiQ is RsmJ, the methyltransferase responsible for methylation of G1516 in 16S rRNA of E. coli.

Basturea GN, Dague DR, Deutscher MP, Rudd KE.

J Mol Biol. 2012 Jan 6;415(1):16-21. doi: 10.1016/j.jmb.2011.10.044. Epub 2011 Nov 4.

22.

Acetylation regulates the stability of a bacterial protein: growth stage-dependent modification of RNase R.

Liang W, Malhotra A, Deutscher MP.

Mol Cell. 2011 Oct 7;44(1):160-6. doi: 10.1016/j.molcel.2011.06.037.

23.

Degradation of ribosomal RNA during starvation: comparison to quality control during steady-state growth and a role for RNase PH.

Basturea GN, Zundel MA, Deutscher MP.

RNA. 2011 Feb;17(2):338-45. doi: 10.1261/rna.2448911. Epub 2010 Dec 6.

24.

A novel mechanism for ribonuclease regulation: transfer-messenger RNA (tmRNA) and its associated protein SmpB regulate the stability of RNase R.

Liang W, Deutscher MP.

J Biol Chem. 2010 Sep 17;285(38):29054-8. doi: 10.1074/jbc.C110.168641. Epub 2010 Aug 5.

25.

Mode of action of RNase BN/RNase Z on tRNA precursors: RNase BN does not remove the CCA sequence from tRNA.

Dutta T, Deutscher MP.

J Biol Chem. 2010 Jul 23;285(30):22874-81. doi: 10.1074/jbc.M110.141101. Epub 2010 May 19.

26.

RNase R is a highly unstable protein regulated by growth phase and stress.

Chen C, Deutscher MP.

RNA. 2010 Apr;16(4):667-72. doi: 10.1261/rna.1981010. Epub 2010 Feb 25.

27.

Rethinking your purification procedure.

Deutscher MP.

Methods Enzymol. 2009;463:809-11. doi: 10.1016/S0076-6879(09)63043-3. No abstract available.

PMID:
19892203
28.

Affi-Gel Blue for nucleic acid removal and early enrichment of nucleotide binding proteins.

Deutscher MP.

Methods Enzymol. 2009;463:343-5. doi: 10.1016/S0076-6879(09)63021-4. Review.

PMID:
19892181
29.

Maintaining protein stability.

Deutscher MP.

Methods Enzymol. 2009;463:121-7. doi: 10.1016/S0076-6879(09)63010-X. Review.

PMID:
19892170
30.

Setting up a laboratory.

Deutscher MP.

Methods Enzymol. 2009;463:37-42. doi: 10.1016/S0076-6879(09)63005-6. Review. No abstract available.

PMID:
19892165
31.

Methods in Enzymology. Preface.

Burgess RR, Deutscher MP.

Methods Enzymol. 2009;463:xxv-xxvi. doi: 10.1016/S0076-6879(09)63049-4. No abstract available.

PMID:
19892160
32.

Preface to chapter 1. Why purify enzymes?

Deutscher MP.

Methods Enzymol. 2009;463:liv. doi: 10.1016/S0076-6879(09)63054-8. No abstract available.

PMID:
19892159
33.

Catalytic properties of RNase BN/RNase Z from Escherichia coli: RNase BN is both an exo- and endoribonuclease.

Dutta T, Deutscher MP.

J Biol Chem. 2009 Jun 5;284(23):15425-31. doi: 10.1074/jbc.M109.005462. Epub 2009 Apr 14.

34.

Insights into how RNase R degrades structured RNA: analysis of the nuclease domain.

Vincent HA, Deutscher MP.

J Mol Biol. 2009 Apr 3;387(3):570-83. doi: 10.1016/j.jmb.2009.01.068. Epub 2009 Feb 10.

35.

Initiation of ribosome degradation during starvation in Escherichia coli.

Zundel MA, Basturea GN, Deutscher MP.

RNA. 2009 May;15(5):977-83. doi: 10.1261/rna.1381309. Epub 2009 Mar 26.

36.

Maturation and degradation of ribosomal RNA in bacteria.

Deutscher MP.

Prog Mol Biol Transl Sci. 2009;85:369-91. doi: 10.1016/S0079-6603(08)00809-X. Review.

PMID:
19215777
37.

Analyzing the decay of stable RNAs in E. coli.

Li Z, Deutscher MP.

Methods Enzymol. 2008;447:31-45. doi: 10.1016/S0076-6879(08)02202-7.

38.
39.

An important role for the multienzyme aminoacyl-tRNA synthetase complex in mammalian translation and cell growth.

Kyriacou SV, Deutscher MP.

Mol Cell. 2008 Feb 29;29(4):419-27. doi: 10.1016/j.molcel.2007.11.038. Erratum in: Mol Cell. 2008 Mar 28;29(6):793-5.

40.

Substrate specificity and properties of the Escherichia coli 16S rRNA methyltransferase, RsmE.

Basturea GN, Deutscher MP.

RNA. 2007 Nov;13(11):1969-76. Epub 2007 Sep 13.

41.

RluD, a highly conserved pseudouridine synthase, modifies 50S subunits more specifically and efficiently than free 23S rRNA.

Vaidyanathan PP, Deutscher MP, Malhotra A.

RNA. 2007 Nov;13(11):1868-76. Epub 2007 Sep 13.

42.

Structural basis for processivity and single-strand specificity of RNase II.

Zuo Y, Vincent HA, Zhang J, Wang Y, Deutscher MP, Malhotra A.

Mol Cell. 2006 Oct 6;24(1):149-56. Epub 2006 Sep 21.

43.

Substrate recognition and catalysis by the exoribonuclease RNase R.

Vincent HA, Deutscher MP.

J Biol Chem. 2006 Oct 6;281(40):29769-75. Epub 2006 Aug 7.

44.

Degradation of RNA in bacteria: comparison of mRNA and stable RNA.

Deutscher MP.

Nucleic Acids Res. 2006 Feb 1;34(2):659-66. Print 2006. Review.

45.

Identification and characterization of RsmE, the founding member of a new RNA base methyltransferase family.

Basturea GN, Rudd KE, Deutscher MP.

RNA. 2006 Mar;12(3):426-34. Epub 2006 Jan 23.

46.

Elevation of RNase R in response to multiple stress conditions.

Chen C, Deutscher MP.

J Biol Chem. 2005 Oct 14;280(41):34393-6. Epub 2005 Aug 31.

47.

The pseudouridine synthase RluD is required for normal ribosome assembly and function in Escherichia coli.

Gutgsell NS, Deutscher MP, Ofengand J.

RNA. 2005 Jul;11(7):1141-52. Epub 2005 May 31.

48.

The RNase Z homologue encoded by Escherichia coli elaC gene is RNase BN.

Ezraty B, Dahlgren B, Deutscher MP.

J Biol Chem. 2005 Apr 29;280(17):16542-5. Epub 2005 Mar 10.

49.

Edward James Ofengand (1932-2004).

Malhotra A, Deutscher MP.

RNA. 2005 Feb;11(2):117-118. Epub 2005 Jan 18. No abstract available.

50.

An important role for RNase R in mRNA decay.

Cheng ZF, Deutscher MP.

Mol Cell. 2005 Jan 21;17(2):313-8.

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