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Items: 33

1.

Safety and pharmacokinetics of higher doses of caspofungin in healthy adult participants.

Migoya EM, Mistry GC, Stone JA, Comisar W, Sun P, Norcross A, Bi S, Winchell GA, Ghosh K, Uemera N, Deutsch PJ, Wagner JA.

J Clin Pharmacol. 2011 Feb;51(2):202-11. doi: 10.1177/0091270010374853. Epub 2010 Aug 2.

PMID:
20679501
2.

Single- and multiple-dose administration of caspofungin in patients with hepatic insufficiency: implications for safety and dosing recommendations.

Mistry GC, Migoya E, Deutsch PJ, Winchell G, Hesney M, Li S, Bi S, Dilzer S, Lasseter KC, Stone JA.

J Clin Pharmacol. 2007 Aug;47(8):951-61.

PMID:
17660480
3.

Pharmacokinetics of ertapenem in patients with varying degrees of renal insufficiency and in patients on hemodialysis.

Mistry GC, Majumdar AK, Swan S, Sica D, Fisher A, Xu Y, Hesney M, Xi L, Wagner JA, Deutsch PJ.

J Clin Pharmacol. 2006 Oct;46(10):1128-38.

PMID:
16988201
4.

Potential for interactions between caspofungin and nelfinavir or rifampin.

Stone JA, Migoya EM, Hickey L, Winchell GA, Deutsch PJ, Ghosh K, Freeman A, Bi S, Desai R, Dilzer SC, Lasseter KC, Kraft WK, Greenberg H, Waldman SA.

Antimicrob Agents Chemother. 2004 Nov;48(11):4306-14.

5.

Disposition of caspofungin: role of distribution in determining pharmacokinetics in plasma.

Stone JA, Xu X, Winchell GA, Deutsch PJ, Pearson PG, Migoya EM, Mistry GC, Xi L, Miller A, Sandhu P, Singh R, deLuna F, Dilzer SC, Lasseter KC.

Antimicrob Agents Chemother. 2004 Mar;48(3):815-23.

6.

Indinavir and rifabutin drug interactions in healthy volunteers.

Kraft WK, McCrea JB, Winchell GA, Carides A, Lowry R, Woolf EJ, Kusma SE, Deutsch PJ, Greenberg HE, Waldman SA.

J Clin Pharmacol. 2004 Mar;44(3):305-13.

PMID:
14973305
7.

Effects of the neurokinin1 receptor antagonist aprepitant on the pharmacokinetics of dexamethasone and methylprednisolone.

McCrea JB, Majumdar AK, Goldberg MR, Iwamoto M, Gargano C, Panebianco DL, Hesney M, Lines CR, Petty KJ, Deutsch PJ, Murphy MG, Gottesdiener KM, Goldwater DR, Blum RA.

Clin Pharmacol Ther. 2003 Jul;74(1):17-24.

PMID:
12844131
8.

Preclinical and clinical pharmacodynamic assessment of L-778,123, a dual inhibitor of farnesyl:protein transferase and geranylgeranyl:protein transferase type-I.

Lobell RB, Liu D, Buser CA, Davide JP, DePuy E, Hamilton K, Koblan KS, Lee Y, Mosser S, Motzel SL, Abbruzzese JL, Fuchs CS, Rowinsky EK, Rubin EH, Sharma S, Deutsch PJ, Mazina KE, Morrison BW, Wildonger L, Yao SL, Kohl NE.

Mol Cancer Ther. 2002 Jul;1(9):747-58.

9.

Single- and multiple-dose pharmacokinetics of caspofungin in healthy men.

Stone JA, Holland SD, Wickersham PJ, Sterrett A, Schwartz M, Bonfiglio C, Hesney M, Winchell GA, Deutsch PJ, Greenberg H, Hunt TL, Waldman SA.

Antimicrob Agents Chemother. 2002 Mar;46(3):739-45.

10.

Pharmacokinetic profile and tolerability of indinavir-ritonavir combinations in healthy volunteers.

Saah AJ, Winchell GA, Nessly ML, Seniuk MA, Rhodes RR, Deutsch PJ.

Antimicrob Agents Chemother. 2001 Oct;45(10):2710-5.

11.

The steady-state disposition of indinavir is not altered by the concomitant administration of clarithromycin.

Boruchoff SE, Sturgill MG, Grasing KW, Seibold JR, McCrea J, Winchell GA, Kusma SE, Deutsch PJ.

Clin Pharmacol Ther. 2000 Apr;67(4):351-9.

PMID:
10801243
12.

Autocrine expression and ontogenetic functions of the PACAP ligand/receptor system during sympathetic development.

DiCicco-Bloom E, Deutsch PJ, Maltzman J, Zhang J, Pintar JE, Zheng J, Friedman WF, Zhou X, Zaremba T.

Dev Biol. 2000 Mar 15;219(2):197-213.

13.

Effect of indinavir on the single-dose pharmacokinetics of theophylline in healthy subjects.

Mistry GC, Laurent A, Sterrett AT, Deutsch PJ.

J Clin Pharmacol. 1999 Jun;39(6):636-42.

PMID:
10354968
14.

A phase I/II study of the protease inhibitor indinavir in children with HIV infection.

Mueller BU, Sleasman J, Nelson RP Jr, Smith S, Deutsch PJ, Ju W, Steinberg SM, Balis FM, Jarosinski PF, Brouwers P, Mistry G, Winchell G, Zwerski S, Sei S, Wood LV, Zeichner S, Pizzo PA.

Pediatrics. 1998 Jul;102(1 Pt 1):101-9.

PMID:
9651421
15.

Single-dose pharmacokinetics of indinavir and the effect of food.

Yeh KC, Deutsch PJ, Haddix H, Hesney M, Hoagland V, Ju WD, Justice SJ, Osborne B, Sterrett AT, Stone JA, Woolf E, Waldman S.

Antimicrob Agents Chemother. 1998 Feb;42(2):332-8. Erratum in: Antimicrob Agents Chemother 1998 May;42(5):1308.

16.

Disposition of indinavir, a potent HIV-1 protease inhibitor, after an oral dose in humans.

Balani SK, Woolf EJ, Hoagland VL, Sturgill MG, Deutsch PJ, Yeh KC, Lin JH.

Drug Metab Dispos. 1996 Dec;24(12):1389-94.

PMID:
8971147
17.

Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor.

Condra JH, Holder DJ, Schleif WA, Blahy OM, Danovich RM, Gabryelski LJ, Graham DJ, Laird D, Quintero JC, Rhodes A, Robbins HL, Roth E, Shivaprakash M, Yang T, Chodakewitz JA, Deutsch PJ, Leavitt RY, Massari FE, Mellors JW, Squires KE, Steigbigel RT, Teppler H, Emini EA.

J Virol. 1996 Dec;70(12):8270-6.

18.

Phenobarbital minimally alters plasma concentrations of losartan and its active metabolite E-3174.

Goldberg MR, Lo MW, Deutsch PJ, Wilson SE, McWilliams EJ, McCrea JB.

Clin Pharmacol Ther. 1996 Mar;59(3):268-74.

PMID:
8653989
19.

Losartan does not affect the pharmacokinetics and pharmacodynamics of warfarin.

Kong AN, Tomasko L, Waldman SA, Osborne B, Deutsch PJ, Goldberg MR, Bjornsson TD.

J Clin Pharmacol. 1995 Oct;35(10):1008-15.

PMID:
8568008
20.
26.

Structural determinants for transcriptional activation by cAMP-responsive DNA elements.

Deutsch PJ, Hoeffler JP, Jameson JL, Lin JC, Habener JF.

J Biol Chem. 1988 Dec 5;263(34):18466-72.

27.

Cyclic AMP and phorbol ester-stimulated transcription mediated by similar DNA elements that bind distinct proteins.

Deutsch PJ, Hoeffler JP, Jameson JL, Habener JF.

Proc Natl Acad Sci U S A. 1988 Nov;85(21):7922-6.

28.

The gonadotropin alpha-gene contains multiple protein binding domains that interact to modulate basal and cAMP-responsive transcription.

Jameson JL, Jaffe RC, Deutsch PJ, Albanese C, Habener JF.

J Biol Chem. 1988 Jul 15;263(20):9879-86.

30.

trans-acting factors interact with a cyclic AMP response element to modulate expression of the human gonadotropin alpha gene.

Jameson JL, Deutsch PJ, Gallagher GD, Jaffe RC, Habener JF.

Mol Cell Biol. 1987 Sep;7(9):3032-40.

31.

Luteinizing hormone-secreting pituitary tumor: biosynthetic characterization and clinical studies.

Klibanski A, Deutsch PJ, Jameson JL, Ridgway EC, Crowley WF, Hsu DW, Habener JF, Black PM.

J Clin Endocrinol Metab. 1987 Mar;64(3):536-42.

PMID:
3102541
32.

Latent insulin receptors and possible receptor precursors in 3T3-L1 adipocytes.

Deutsch PJ, Wan CF, Rosen OM, Rubin CS.

Proc Natl Acad Sci U S A. 1983 Jan;80(1):133-6.

33.

Identification and characterization of a latent pool of insulin receptors in 3T3-L1 adipocytes.

Deutsch PJ, Rosen OM, Rubin CS.

J Biol Chem. 1982 May 25;257(10):5350-8. No abstract available.

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