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Extra-Chromosomal DNA Sequencing Reveals Episomal Prophages Capable of Impacting Virulence Factor Expression in Staphylococcus aureus.

Deutsch DR, Utter B, Verratti KJ, Sichtig H, Tallon LJ, Fischetti VA.

Front Microbiol. 2018 Jul 2;9:1406. doi: 10.3389/fmicb.2018.01406. eCollection 2018.


SAR studies on truxillic acid mono esters as a new class of antinociceptive agents targeting fatty acid binding proteins.

Yan S, Elmes MW, Tong S, Hu K, Awwa M, Teng GYH, Jing Y, Freitag M, Gan Q, Clement T, Wei L, Sweeney JM, Joseph OM, Che J, Carbonetti GS, Wang L, Bogdan DM, Falcone J, Smietalo N, Zhou Y, Ralph B, Hsu HC, Li H, Rizzo RC, Deutsch DG, Kaczocha M, Ojima I.

Eur J Med Chem. 2018 Jun 25;154:233-252. doi: 10.1016/j.ejmech.2018.04.050. Epub 2018 May 26.


Fatty acid-binding proteins 5 and 7 gene deletion increases sucrose consumption and diminishes forced swim immobility time.

Hamilton J, Koumas C, Clavin BH, Marion M, Figueiredo A, Gonzalez S, O'Rourke JR, Deutsch D, Kaczocha M, Haj-Dahmane S, Thanos PK.

Behav Pharmacol. 2018 Sep;29(6):503-508. doi: 10.1097/FBP.0000000000000402.


Fatty-acid-binding protein 5 controls retrograde endocannabinoid signaling at central glutamate synapses.

Haj-Dahmane S, Shen RY, Elmes MW, Studholme K, Kanjiya MP, Bogdan D, Thanos PK, Miyauchi JT, Tsirka SE, Deutsch DG, Kaczocha M.

Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):3482-3487. doi: 10.1073/pnas.1721339115. Epub 2018 Mar 12.


Fatty acid binding protein deletion prevents stress-induced preference for cocaine and dampens stress-induced corticosterone levels.

Hamilton J, Marion M, Figueiredo A, Clavin BH, Deutsch D, Kaczocha M, Haj-Dahmane S, Thanos PK.

Synapse. 2018 Jun;72(6):e22031. doi: 10.1002/syn.22031. Epub 2018 Feb 19.


Pharmacological Inhibition of Brain Fatty Acid Binding Protein Reduces Ethanol Consumption in Mice.

Figueiredo A, Hamilton J, Marion M, Blum K, Kaczocha M, Haj-Dahmane S, Deutsch D, Thanos PK.

J Reward Defic Syndr Addict Sci. 2017;3(2):21-27. Epub 2017 Oct 31.


A novel plasmid, pSAA0430-08, from Streptococcus anginosus subsp. anginosus strain 0430-08.

Tabata A, Deutsch D, Otsuka S, Verratti K, Tomoyasu T, Nagamune H, Fischetti VA.

Plasmid. 2018 Jan;95:16-27. doi: 10.1016/j.plasmid.2018.01.002.


The Antinociceptive Agent SBFI-26 Binds to Anandamide Transporters FABP5 and FABP7 at Two Different Sites.

Hsu HC, Tong S, Zhou Y, Elmes MW, Yan S, Kaczocha M, Deutsch DG, Rizzo RC, Ojima I, Li H.

Biochemistry. 2017 Jul 11;56(27):3454-3462. doi: 10.1021/acs.biochem.7b00194. Epub 2017 Jun 28.


Direct oral anticoagulants and digestive bleeding: therapeutic management and preventive measures.

Deutsch D, Boustière C, Ferrari E, Albaladejo P, Morange PE, Benamouzig R.

Therap Adv Gastroenterol. 2017 Jun;10(6):495-505. doi: 10.1177/1756283X17702092. Epub 2017 Apr 17. Review.


Evolutionary Analysis of the Mammalian Tuftelin Sequence Reveals Features of Functional Importance.

Delgado S, Deutsch D, Sire JY.

J Mol Evol. 2017 Apr;84(4):214-224. doi: 10.1007/s00239-017-9789-5. Epub 2017 Apr 13.


Fatty-acid-binding protein inhibition produces analgesic effects through peripheral and central mechanisms.

Peng X, Studholme K, Kanjiya MP, Luk J, Bogdan D, Elmes MW, Carbonetti G, Tong S, Gary Teng YH, Rizzo RC, Li H, Deutsch DG, Ojima I, Rebecchi MJ, Puopolo M, Kaczocha M.

Mol Pain. 2017 Jan;13:1744806917697007. doi: 10.1177/1744806917697007.


Uncovering novel mobile genetic elements and their dynamics through an extra-chromosomal sequencing approach.

Deutsch DR, Utter B, Fischetti VA.

Mob Genet Elements. 2016 May 17;6(4):e1189987. doi: 10.1080/2159256X.2016.1189987. eCollection 2016 Jul-Aug.


Examination of the Addictive and Behavioral Properties of Fatty Acid-Binding Protein Inhibitor SBFI26.

Thanos PK, Clavin BH, Hamilton J, O'Rourke JR, Maher T, Koumas C, Miao E, Lankop J, Elhage A, Haj-Dahmane S, Deutsch D, Kaczocha M.

Front Psychiatry. 2016 Apr 5;7:54. doi: 10.3389/fpsyt.2016.00054. eCollection 2016.


Skeletal ligament healing using the recombinant human amelogenin protein.

Hanhan S, Ejzenberg A, Goren K, Saba F, Suki Y, Sharon S, Shilo D, Waxman J, Spitzer E, Shahar R, Atkins A, Liebergall M, Blumenfeld A, Deutsch D, Haze A.

J Cell Mol Med. 2016 May;20(5):815-24. doi: 10.1111/jcmm.12762. Epub 2016 Feb 24.


Novel Engineered Peptides of a Phage Lysin as Effective Antimicrobials against Multidrug-Resistant Acinetobacter baumannii.

Thandar M, Lood R, Winer BY, Deutsch DR, Euler CW, Fischetti VA.

Antimicrob Agents Chemother. 2016 Apr 22;60(5):2671-9. doi: 10.1128/AAC.02972-15. Print 2016 May.


Targeted Curing of All Lysogenic Bacteriophage from Streptococcus pyogenes Using a Novel Counter-selection Technique.

Euler CW, Juncosa B, Ryan PA, Deutsch DR, McShan WM, Fischetti VA.

PLoS One. 2016 Jan 12;11(1):e0146408. doi: 10.1371/journal.pone.0146408. eCollection 2016.


Postovulatory aging affects dynamics of mRNA, expression and localization of maternal effect proteins, spindle integrity and pericentromeric proteins in mouse oocytes.

Trapphoff T, Heiligentag M, Dankert D, Demond H, Deutsch D, Fröhlich T, Arnold GJ, Grümmer R, Horsthemke B, Eichenlaub-Ritter U.

Hum Reprod. 2016 Jan;31(1):133-49. doi: 10.1093/humrep/dev279. Epub 2015 Nov 17.


Toxicity assessment and bioaccumulation in zebrafish embryos exposed to carbon nanotubes suspended in Pluronic® F-108.

Wang R, N Meredith A, Lee M Jr, Deutsch D, Miadzvedskaya L, Braun E, Pantano P, Harper S, Draper R.

Nanotoxicology. 2016 Aug;10(6):689-98. doi: 10.3109/17435390.2015.1107147. Epub 2015 Nov 11.


Q&A: David Deutsch. Objective beauty.

Deutsch D, Sainani KL.

Nature. 2015 Oct 8;526(7572):S16. doi: 10.1038/526S16a. No abstract available.


Fatty acid-binding proteins (FABPs) are intracellular carriers for Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD).

Elmes MW, Kaczocha M, Berger WT, Leung K, Ralph BP, Wang L, Sweeney JM, Miyauchi JT, Tsirka SE, Ojima I, Deutsch DG.

J Biol Chem. 2015 Apr 3;290(14):8711-21. doi: 10.1074/jbc.M114.618447. Epub 2015 Feb 9.


Constructor theory of information.

Deutsch D, Marletto C.

Proc Math Phys Eng Sci. 2015 Feb 8;471(2174):20140540.


Proteome analysis of early lineage specification in bovine embryos.

Demant M, Deutsch DR, Fröhlich T, Wolf E, Arnold GJ.

Proteomics. 2015 Feb;15(4):688-701. doi: 10.1002/pmic.201400251. Epub 2014 Oct 9.


Stage-specific proteome signatures in early bovine embryo development.

Deutsch DR, Fröhlich T, Otte KA, Beck A, Habermann FA, Wolf E, Arnold GJ.

J Proteome Res. 2014 Oct 3;13(10):4363-76. doi: 10.1021/pr500550t. Epub 2014 Sep 10.


Beyond the chromosome: the prevalence of unique extra-chromosomal bacteriophages with integrated virulence genes in pathogenic Staphylococcus aureus.

Utter B, Deutsch DR, Schuch R, Winer BY, Verratti K, Bishop-Lilly K, Sozhamannan S, Fischetti VA.

PLoS One. 2014 Jun 25;9(6):e100502. doi: 10.1371/journal.pone.0100502. eCollection 2014.


Dynamic relationship of the epithelium and mesenchyme during salivary gland initiation: the role of Fgf10.

Wells KL, Gaete M, Matalova E, Deutsch D, Rice D, Tucker AS.

Biol Open. 2014 Jun 23;3(7):677. doi: 10.1242/bio.20149084. No abstract available.


Inhibition of fatty acid binding proteins elevates brain anandamide levels and produces analgesia.

Kaczocha M, Rebecchi MJ, Ralph BP, Teng YH, Berger WT, Galbavy W, Elmes MW, Glaser ST, Wang L, Rizzo RC, Deutsch DG, Ojima I.

PLoS One. 2014 Apr 4;9(4):e94200. doi: 10.1371/journal.pone.0094200. eCollection 2014.


Crystallographic study of FABP5 as an intracellular endocannabinoid transporter.

Sanson B, Wang T, Sun J, Wang L, Kaczocha M, Ojima I, Deutsch D, Li H.

Acta Crystallogr D Biol Crystallogr. 2014 Feb;70(Pt 2):290-8. doi: 10.1107/S1399004713026795. Epub 2014 Jan 29.


Bis(dimethyl sulfoxide-κO)tetra-kis-(μ2-3,4,5-tri-meth-oxy-benzoato-κ(2) O:O')dizinc.

Deutsch D, Zevaco T, Walter O.

Acta Crystallogr Sect E Struct Rep Online. 2013 Aug 23;69(Pt 9):m519. doi: 10.1107/S1600536813023118. eCollection 2013.


Tactile modulation of whisking via the brainstem loop: statechart modeling and experimental validation.

Sherman D, Oram T, Deutsch D, Gordon G, Ahissar E, Harel D.

PLoS One. 2013 Nov 27;8(11):e79831. doi: 10.1371/journal.pone.0079831. eCollection 2013.


Role of FAAH-like anandamide transporter in anandamide inactivation.

Leung K, Elmes MW, Glaser ST, Deutsch DG, Kaczocha M.

PLoS One. 2013 Nov 4;8(11):e79355. doi: 10.1371/journal.pone.0079355. eCollection 2013.


Absolute pitch among students at the Shanghai Conservatory of Music: a large-scale direct-test study.

Deutsch D, Li X, Shen J.

J Acoust Soc Am. 2013 Nov;134(5):3853-9. doi: 10.1121/1.4824450.


Dynamic relationship of the epithelium and mesenchyme during salivary gland initiation: the role of Fgf10.

Wells KL, Gaete M, Matalova E, Deutsch D, Rice D, Tucker AS.

Biol Open. 2013 Aug 9;2(10):981-9. doi: 10.1242/bio.20135306. eCollection 2013.


On-line perception of Mandarin Tones 2 and 3: evidence from eye movements.

Shen J, Deutsch D, Rayner K.

J Acoust Soc Am. 2013 May;133(5):3016-29. doi: 10.1121/1.4795775.


Pre-neuronal morphological processing of object location by individual whiskers.

Bagdasarian K, Szwed M, Knutsen PM, Deutsch D, Derdikman D, Pietr M, Simony E, Ahissar E.

Nat Neurosci. 2013 May;16(5):622-31. doi: 10.1038/nn.3378. Epub 2013 Apr 7.


Absolute pitch is associated with a large auditory digit span: a clue to its genesis.

Deutsch D, Dooley K.

J Acoust Soc Am. 2013 Apr;133(4):1859-61. doi: 10.1121/1.4792217.


Biosynthetic pathways of bioactive N-acylethanolamines in brain.

Tsuboi K, Ikematsu N, Uyama T, Deutsch DG, Tokumura A, Ueda N.

CNS Neurol Disord Drug Targets. 2013 Feb 1;12(1):7-16. Review.


Targeting fatty acid binding protein (FABP) anandamide transporters - a novel strategy for development of anti-inflammatory and anti-nociceptive drugs.

Berger WT, Ralph BP, Kaczocha M, Sun J, Balius TE, Rizzo RC, Haj-Dahmane S, Ojima I, Deutsch DG.

PLoS One. 2012;7(12):e50968. doi: 10.1371/journal.pone.0050968. Epub 2012 Dec 7.


Fast feedback in active sensing: touch-induced changes to whisker-object interaction.

Deutsch D, Pietr M, Knutsen PM, Ahissar E, Schneidman E.

PLoS One. 2012;7(9):e44272. doi: 10.1371/journal.pone.0044272. Epub 2012 Sep 18.


Beyond the quantum horizon.

Deutsch D, Ekert A.

Sci Am. 2012 Sep;307(3):84-9. No abstract available.


Anandamide externally added to lipid vesicles containing trapped fatty acid amide hydrolase (FAAH) is readily hydrolyzed in a sterol-modulated fashion.

Kaczocha M, Lin Q, Nelson LD, McKinney MK, Cravatt BF, London E, Deutsch DG.

ACS Chem Neurosci. 2012 May 16;3(5):364-8. doi: 10.1021/cn300001w. Epub 2012 Jan 18.


Speech versus song: multiple pitch-sensitive areas revealed by a naturally occurring musical illusion.

Tierney A, Dick F, Deutsch D, Sereno M.

Cereb Cortex. 2013 Feb;23(2):249-54. doi: 10.1093/cercor/bhs003. Epub 2012 Feb 7.


Biphasic influence of hypoxia on tuftelin expression in mouse mesenchymal C3H10T1/2 stem cells.

Deutsch D, Silverstein N, Shilo D, Lecht S, Lazarovici P, Blumenfeld A.

Eur J Oral Sci. 2011 Dec;119 Suppl 1:55-61. doi: 10.1111/j.1600-0722.2011.00861.x.


Absolute pitch correlates with high performance on interval naming tasks.

Dooley K, Deutsch D.

J Acoust Soc Am. 2011 Dec;130(6):4097-104. doi: 10.1121/1.3652861.


Fatty acid-binding proteins transport N-acylethanolamines to nuclear receptors and are targets of endocannabinoid transport inhibitors.

Kaczocha M, Vivieca S, Sun J, Glaser ST, Deutsch DG.

J Biol Chem. 2012 Jan 27;287(5):3415-24. doi: 10.1074/jbc.M111.304907. Epub 2011 Dec 14.


Enzymatic formation of N-acylethanolamines from N-acylethanolamine plasmalogen through N-acylphosphatidylethanolamine-hydrolyzing phospholipase D-dependent and -independent pathways.

Tsuboi K, Okamoto Y, Ikematsu N, Inoue M, Shimizu Y, Uyama T, Wang J, Deutsch DG, Burns MP, Ulloa NM, Tokumura A, Ueda N.

Biochim Biophys Acta. 2011 Oct;1811(10):565-77. doi: 10.1016/j.bbalip.2011.07.009. Epub 2011 Jul 23.


Studies on the anorectic effect of N-acylphosphatidylethanolamine and phosphatidylethanolamine in mice.

Wellner N, Tsuboi K, Madsen AN, Holst B, Diep TA, Nakao M, Tokumura A, Burns MP, Deutsch DG, Ueda N, Hansen HS.

Biochim Biophys Acta. 2011 Sep;1811(9):508-12. doi: 10.1016/j.bbalip.2011.06.020. Epub 2011 Jun 23.


Endocannabinoid tone versus constitutive activity of cannabinoid receptors.

Howlett AC, Reggio PH, Childers SR, Hampson RE, Ulloa NM, Deutsch DG.

Br J Pharmacol. 2011 Aug;163(7):1329-43. doi: 10.1111/j.1476-5381.2011.01364.x. Review.


Unique pathway for anandamide synthesis and liver regeneration.

Izzo AA, Deutsch DG.

Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6339-40. doi: 10.1073/pnas.1103566108. Epub 2011 Apr 13. No abstract available.


Illusory transformation from speech to song.

Deutsch D, Henthorn T, Lapidis R.

J Acoust Soc Am. 2011 Apr;129(4):2245-52. doi: 10.1121/1.3562174.


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