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Items: 1 to 50 of 74

1.

Multidomain analyses of a longitudinal human microbiome intestinal cleanout perturbation experiment.

Fukuyama J, Rumker L, Sankaran K, Jeganathan P, Dethlefsen L, Relman DA, Holmes SP.

PLoS Comput Biol. 2017 Aug 18;13(8):e1005706. doi: 10.1371/journal.pcbi.1005706. eCollection 2017 Aug.

2.

Distinct distal gut microbiome diversity and composition in healthy children from Bangladesh and the United States.

Lin A, Bik EM, Costello EK, Dethlefsen L, Haque R, Relman DA, Singh U.

PLoS One. 2013;8(1):e53838. doi: 10.1371/journal.pone.0053838. Epub 2013 Jan 22.

3.

The application of ecological theory toward an understanding of the human microbiome.

Costello EK, Stagaman K, Dethlefsen L, Bohannan BJ, Relman DA.

Science. 2012 Jun 8;336(6086):1255-62. doi: 10.1126/science.1224203. Epub 2012 Jun 6. Review.

4.

Comparisons of distance methods for combining covariates and abundances in microbiome studies.

Fukuyama J, McMurdie PJ, Dethlefsen L, Relman DA, Holmes S.

Pac Symp Biocomput. 2012:213-24.

5.

Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation.

Dethlefsen L, Relman DA.

Proc Natl Acad Sci U S A. 2011 Mar 15;108 Suppl 1:4554-61. doi: 10.1073/pnas.1000087107. Epub 2010 Sep 16.

6.

Exploring microbial diversity and taxonomy using SSU rRNA hypervariable tag sequencing.

Huse SM, Dethlefsen L, Huber JA, Mark Welch D, Relman DA, Sogin ML.

PLoS Genet. 2008 Nov;4(11):e1000255. doi: 10.1371/journal.pgen.1000255. Epub 2008 Nov 21. Erratum in: PLoS Genet. 2008 Dec;4(12). doi: 10.1371/annotation/3d8a6578-ce56-45aa-bc71-05078355b851. Welch, David Mark [corrected to Mark Welch, David].

7.

The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing.

Dethlefsen L, Huse S, Sogin ML, Relman DA.

PLoS Biol. 2008 Nov 18;6(11):e280. doi: 10.1371/journal.pbio.0060280.

8.

An ecological and evolutionary perspective on human-microbe mutualism and disease.

Dethlefsen L, McFall-Ngai M, Relman DA.

Nature. 2007 Oct 18;449(7164):811-8. Review.

PMID:
17943117
9.

Performance of the translational apparatus varies with the ecological strategies of bacteria.

Dethlefsen L, Schmidt TM.

J Bacteriol. 2007 Apr;189(8):3237-45. Epub 2007 Feb 2.

10.

The importance of individuals and scale: moving towards single cell microbiology.

Dethlefsen L, Relman DA.

Environ Microbiol. 2007 Jan;9(1):8-10. No abstract available.

PMID:
17227405
11.

Assembly of the human intestinal microbiota.

Dethlefsen L, Eckburg PB, Bik EM, Relman DA.

Trends Ecol Evol. 2006 Sep;21(9):517-23. Epub 2006 Jul 3. Review.

PMID:
16820245
12.

Diversity of the human intestinal microbial flora.

Eckburg PB, Bik EM, Bernstein CN, Purdom E, Dethlefsen L, Sargent M, Gill SR, Nelson KE, Relman DA.

Science. 2005 Jun 10;308(5728):1635-8. Epub 2005 Apr 14.

13.
14.

Characterization of camptothecin-resistant Chinese hamster lung cells.

Chang JY, Dethlefsen LA, Barley LR, Zhou BS, Cheng YC.

Biochem Pharmacol. 1992 Jun 9;43(11):2443-52. Erratum in: Biochem Pharmacol 1993 Feb 9;45(3):787.

PMID:
1319161
15.

Poly(ADP-ribose) metabolism in proliferating versus quiescent cells and its relationship to their radiation responses.

Sweigert SE, Marston JM, Dethlefsen LA.

Int J Radiat Biol. 1990 Jul;58(1):111-23.

PMID:
1973429
16.
17.

The physiological state as a modifier of radiation-induced cytotoxicity in heterogeneous murine tumor cells growing in vitro.

Cheng WY, Ridinger DN, Lehman CM, Puryear RL, Dethlefsen LA.

Int J Radiat Biol. 1989 Oct;56(4):463-83.

PMID:
2571659
18.

Repair of DNA single- and double-strand breaks in proliferating and quiescent murine tumor cells.

Sweigert SE, Eguchi-Kasai K, Warters RL, Dethlefsen LA.

Int J Radiat Biol. 1989 Sep;56(3):253-64.

PMID:
2570811
19.

Cell cycle effect on the induction of DNA double-strand breaks by X rays.

Sweigert SE, Rowley R, Warters RL, Dethlefsen LA.

Radiat Res. 1988 Nov;116(2):228-44.

PMID:
3186934
20.

Toxic effects of acute glutathione depletion by buthionine sulfoximine and dimethylfumarate on murine mammary carcinoma cells.

Dethlefsen LA, Lehman CM, Biaglow JE, Peck VM.

Radiat Res. 1988 May;114(2):215-24.

PMID:
3375425
21.

Endogenous thiol levels in heterogeneous murine tumor cells as a function of the physiological state and the response to X-irradiation.

Dethlefsen LA, Biaglow JE, Peck VM, Ridinger DN.

J Cell Physiol. 1987 Jul;132(1):149-54.

PMID:
3597550
22.

Morphometric changes as a function of the proliferative status of murine mammary carcinoma cells.

Yasui LS, Dethlefsen LA.

Scanning Microsc. 1987 Jun;1(2):791-7.

PMID:
3616575
23.

A calmodulin antagonist has no effect on the repair of X-ray-induced damage in a murine mammary carcinoma cell line.

Ridinger DN, Loh SN, Warters RL, Dethlefsen LA.

Radiat Res. 1986 Nov;108(2):127-38.

PMID:
3786673
24.

The effect of pH on potentially lethal damage recovery in A549 cells.

Varnes ME, Dethlefsen LA, Biaglow JE.

Radiat Res. 1986 Oct;108(1):80-90.

PMID:
3774969
25.

Localized hyperthermia and X-irradiation of murine jejunum in situ: a new method.

Peck JW, Gibbs FA Jr, Dethlefsen LA.

Int J Hyperthermia. 1986 Jul-Sep;2(3):277-98.

PMID:
3794422
26.

Toxic effects of extended glutathione depletion by buthionine sulfoximine on murine mammary carcinoma cells.

Dethlefsen LA, Biaglow JE, Peck VM, Ridinger DN.

Int J Radiat Oncol Biol Phys. 1986 Jul;12(7):1157-60.

PMID:
3744934
27.

The effect of L-buthionine sulfoximine on the aerobic radiation response of A549 human lung carcinoma cells.

Biaglow JE, Varnes ME, Tuttle SW, Oleinick NL, Glazier K, Clark EP, Epp ER, Dethlefsen LA.

Int J Radiat Oncol Biol Phys. 1986 Jul;12(7):1139-42.

PMID:
3744931
28.

Poly(ADP-ribose) polymerase activity in proliferating and quiescent murine mammary carcinoma cells.

Sweiger SE, Petzold SJ, Surowy CS, Berger SJ, Dethlefsen LA, Berger NA.

Radiat Res. 1986 Feb;105(2):219-26.

PMID:
3081939
29.

Heterogeneity of X-ray cytotoxicity in proliferating and quiescent murine mammary carcinoma cells.

Wallen CA, Ridinger DN, Dethlefsen LA.

Cancer Res. 1985 Jul;45(7):3064-9.

30.

Fluorescence studies of Hoechst 33342 with supercoiled and relaxed plasmid pBR322 DNA.

Sandhu LC, Warters RL, Dethlefsen LA.

Cytometry. 1985 May;6(3):191-4.

31.

DNA damage repair in quiescent murine mammary carcinoma cells in culture.

Warters RL, Lyons BW, Ridinger DN, Dethlefsen LA.

Biochim Biophys Acta. 1985 Apr 19;824(4):357-64.

PMID:
3986208
32.

DNase I sensitivity of nuclear DNA measured by flow cytometry.

Roti Roti JL, Wright WD, Higashikubo R, Dethlefsen LA.

Cytometry. 1985 Mar;6(2):101-8.

33.

Delayed enhanced effects of Adriamycin on the X-irradiation-induced gastrointestinal toxicity in mice.

Dethlefsen LA, Riley RM, Lehman CM.

Radiat Res. 1984 Oct;100(1):157-70.

PMID:
6387775
34.

Murine mammary tumour cells in vitro. II. Recruitment of quiescent cells.

Wallen CA, Higashikubo R, Dethlefsen LA.

Cell Tissue Kinet. 1984 Jan;17(1):79-89.

PMID:
6198085
35.

Murine mammary tumour cells in vitro. I. The development of a quiescent state.

Wallen CA, Higashikubo R, Dethlefsen LA.

Cell Tissue Kinet. 1984 Jan;17(1):65-77.

PMID:
6198084
36.

Molecular cloning of the 3'-proximal third of Sendai virus genome.

Dowling PC, Giorgi C, Roux L, Dethlefsen LA, Galantowicz ME, Blumberg BM, Kolakofsky D.

Proc Natl Acad Sci U S A. 1983 Sep;80(17):5213-6.

37.

In vitro synthesis of the nonstructural C protein of Sendai virus.

Dethlefsen L, Kolakofsky D.

J Virol. 1983 Apr;46(1):321-4.

38.

Comparison of two flow cytometric assays for cellular RNA--acridine orange and propidium iodide.

Wallen CA, Higashikubo R, Dethlefsen LA.

Cytometry. 1982 Nov;3(3):155-60.

39.

Adriamycin effects and the interactions of adriamycin with X irradiation on murine mammary tumors.

Dethlefsen LA, Riley RM.

Radiat Res. 1982 Apr;90(1):165-72. No abstract available.

PMID:
7063633
40.

The importance of intratumor temperature uniformity in the study of radiosensitizing effects of hyperthermia in vivo.

Gibbs FA Jr, Peck JW, Dethlefsen LA.

Radiat Res. 1981 Jul;87(1):187-97. No abstract available.

PMID:
7255671
42.

Duodenal crypt survival and crypt cellular recovery kinetics following combined treatment with adriamycin and X irradiation.

Dethlefsen LA, Riley RM.

Radiat Res. 1980 Sep;83(3):644-57. No abstract available.

PMID:
7413926
43.

Analytical cytometric approaches to heterogeneous cell populations in solid tumors: a review.

Dethlefsen LA, Bauer KD, Riley RM.

Cytometry. 1980 Sep;1(2):89-108. Review.

44.

The combined effects of hydroxyurea and X irradiation on murine duodenal mucosa and host survival.

Dethlefsen LA, Ohlsen JD, Riley RM.

Radiat Res. 1980 Jun;82(3):518-25. No abstract available.

PMID:
7384417
45.

Total cellular RNA content: correlation between flow cytometry and ultraviolet spectroscopy.

Bauer KD, Dethlefsen LA.

J Histochem Cytochem. 1980 Jun;28(6):493-8.

PMID:
6156196
46.

Matrix algebraic simulation of mitotic cell selection experiments.

Tomasovic SP, Roti Roti JL, Dethlefsen LA.

Cell Tissue Kinet. 1980 Mar;13(2):117-33.

PMID:
7363299
47.

Alteration of murine mammary tumor metastasis and growth by cytomegalovirus infection.

Olsen GA, Glasgow LA, Dethlefsen LA.

Cancer Res. 1980 Mar;40(3):853-60.

48.

Time-temperature relationships for heat-induced killing of mammalian cells.

Henle KJ, Dethlefsen LA.

Ann N Y Acad Sci. 1980;335:234-53. No abstract available.

PMID:
6931521
49.

Fractionation of combined heat and radiation in asynchronous CHO cells. II. The role of cell-cycle redistribution.

Tomasovic SP, Henle KJ, Dethlefsen LA.

Radiat Res. 1979 Nov;80(2):378-88. No abstract available.

PMID:
504584
50.

Fractionation of combined heat and radiation in asynchronous CHO cells. I. Effects on radiation sensitivity.

Henle KJ, Tomasovic SP, Dethlefsen LA.

Radiat Res. 1979 Nov;80(2):369-77. No abstract available.

PMID:
504583

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