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Items: 32

1.

Fluorescence monitoring of rare circulating tumor cell and cluster dissemination in a multiple myeloma xenograft model in vivo.

Patil R, Tan X, Bartosik P, Detappe A, Runnels JM, Ghobrial I, Lin CP, Niedre M.

J Biomed Opt. 2019 Aug;24(8):1-11. doi: 10.1117/1.JBO.24.8.085004.

2.

Author Correction: Mitochondrial metabolism promotes adaptation to proteotoxic stress.

Tsvetkov P, Detappe A, Cai K, Keys HR, Brune Z, Ying W, Thiru P, Reidy M, Kugener G, Rossen J, Kocak M, Kory N, Tsherniak A, Santagata S, Whitesell L, Ghobrial IM, Markley JL, Lindquist S, Golub TR.

Nat Chem Biol. 2019 Jul;15(7):757. doi: 10.1038/s41589-019-0315-5.

PMID:
31164776
3.

Mitochondrial metabolism promotes adaptation to proteotoxic stress.

Tsvetkov P, Detappe A, Cai K, Keys HR, Brune Z, Ying W, Thiru P, Reidy M, Kugener G, Rossen J, Kocak M, Kory N, Tsherniak A, Santagata S, Whitesell L, Ghobrial IM, Markley JL, Lindquist S, Golub TR.

Nat Chem Biol. 2019 Jul;15(7):681-689. doi: 10.1038/s41589-019-0291-9. Epub 2019 May 27. Erratum in: Nat Chem Biol. 2019 Jun 4;:.

PMID:
31133756
4.

DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells.

He YJ, Meghani K, Caron MC, Yang C, Ronato DA, Bian J, Sharma A, Moore J, Niraj J, Detappe A, Doench JG, Legube G, Root DE, D'Andrea AD, Drané P, De S, Konstantinopoulos PA, Masson JY, Chowdhury D.

Nature. 2018 Nov;563(7732):522-526. doi: 10.1038/s41586-018-0670-5. Epub 2018 Oct 31.

PMID:
30464262
5.

Triply Loaded Nitroxide Brush-Arm Star Polymers Enable Metal-Free Millimetric Tumor Detection by Magnetic Resonance Imaging.

Nguyen HV, Detappe A, Gallagher NM, Zhang H, Harvey P, Yan C, Mathieu C, Golder MR, Jiang Y, Ottaviani MF, Jasanoff A, Rajca A, Ghobrial I, Ghoroghchian PP, Johnson JA.

ACS Nano. 2018 Nov 27;12(11):11343-11354. doi: 10.1021/acsnano.8b06160. Epub 2018 Nov 2.

6.

AGuIX® from bench to bedside-Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine.

Lux F, Tran VL, Thomas E, Dufort S, Rossetti F, Martini M, Truillet C, Doussineau T, Bort G, Denat F, Boschetti F, Angelovski G, Detappe A, Crémillieux Y, Mignet N, Doan BT, Larrat B, Meriaux S, Barbier E, Roux S, Fries P, Müller A, Abadjian MC, Anderson C, Canet-Soulas E, Bouziotis P, Barberi-Heyob M, Frochot C, Verry C, Balosso J, Evans M, Sidi-Boumedine J, Janier M, Butterworth K, McMahon S, Prise K, Aloy MT, Ardail D, Rodriguez-Lafrasse C, Porcel E, Lacombe S, Berbeco R, Allouch A, Perfettini JL, Chargari C, Deutsch E, Le Duc G, Tillement O.

Br J Radiol. 2018 Sep 18:20180365. doi: 10.1259/bjr.20180365. [Epub ahead of print]

PMID:
30226413
7.

Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein.

Botuyan MV, Cui G, Drané P, Oliveira C, Detappe A, Brault ME, Parnandi N, Chaubey S, Thompson JR, Bragantini B, Zhao D, Chapman JR, Chowdhury D, Mer G.

Nat Struct Mol Biol. 2018 Jul;25(7):591-600. doi: 10.1038/s41594-018-0083-z. Epub 2018 Jul 2.

8.

Advancements in Nanomedicine for Multiple Myeloma.

Detappe A, Bustoros M, Mouhieddine TH, Ghoroghchian PP.

Trends Mol Med. 2018 Jun;24(6):560-574. doi: 10.1016/j.molmed.2018.04.005. Epub 2018 May 17. Review.

PMID:
29773319
9.

Antibody-Dependent Cellular Phagocytosis by Macrophages is a Novel Mechanism of Action of Elotuzumab.

Kurdi AT, Glavey SV, Bezman NA, Jhatakia A, Guerriero JL, Manier S, Moschetta M, Mishima Y, Roccaro A, Detappe A, Liu CJ, Sacco A, Huynh D, Tai YT, Robbins MD, Azzi J, Ghobrial IM.

Mol Cancer Ther. 2018 Jul;17(7):1454-1463. doi: 10.1158/1535-7163.MCT-17-0998. Epub 2018 Apr 13.

10.

Multifaceted Impact of MicroRNA 493-5p on Genome-Stabilizing Pathways Induces Platinum and PARP Inhibitor Resistance in BRCA2-Mutated Carcinomas.

Meghani K, Fuchs W, Detappe A, Drané P, Gogola E, Rottenberg S, Jonkers J, Matulonis U, Swisher EM, Konstantinopoulos PA, Chowdhury D.

Cell Rep. 2018 Apr 3;23(1):100-111. doi: 10.1016/j.celrep.2018.03.038.

11.

Differences in Nanoparticle Uptake in Transplanted and Autochthonous Models of Pancreatic Cancer.

Tao Z, Muzumdar MD, Detappe A, Huang X, Xu ES, Yu Y, Mouhieddine TH, Song H, Jacks T, Ghoroghchian PP.

Nano Lett. 2018 Apr 11;18(4):2195-2208. doi: 10.1021/acs.nanolett.7b04043. Epub 2018 Mar 21.

12.

Publisher Correction: Nanoparticle conjugates of a highly potent toxin enhance safety and circumvent platinum resistance in ovarian cancer.

Qi R, Wang Y, Bruno PM, Xiao H, Yu Y, Li T, Lauffer S, Wei W, Chen Q, Kang X, Song H, Yang X, Huang X, Detappe A, Matulonis U, Pepin D, Hemann MT, Birrer MJ, Ghoroghchian PP.

Nat Commun. 2018 Feb 7;9(1):628. doi: 10.1038/s41467-018-02963-0.

13.

The bone-marrow niche in MDS and MGUS: implications for AML and MM.

Ghobrial IM, Detappe A, Anderson KC, Steensma DP.

Nat Rev Clin Oncol. 2018 Apr;15(4):219-233. doi: 10.1038/nrclinonc.2017.197. Epub 2018 Jan 9. Review.

PMID:
29311715
14.

Nanoparticle conjugates of a highly potent toxin enhance safety and circumvent platinum resistance in ovarian cancer.

Qi R, Wang Y, Bruno PM, Xiao H, Yu Y, Li T, Lauffer S, Wei W, Chen Q, Kang X, Song H, Yang X, Huang X, Detappe A, Matulonis U, Pepin D, Hemann MT, Birrer MJ, Ghoroghchian PP.

Nat Commun. 2017 Dec 18;8(1):2166. doi: 10.1038/s41467-017-02390-7. Erratum in: Nat Commun. 2018 Feb 7;9(1):628.

15.

NIR-emissive PEG-b-TCL micelles for breast tumor imaging and minimally invasive pharmacokinetic analysis.

Hofmann CL, O'Sullivan MC, Detappe A, Yu Y, Yang X, Qi W, Landon CD, Therien MJ, Dewhirst MW, Ghoroghchian PP, Palmer GM.

Nanoscale. 2017 Sep 21;9(36):13465-13476. doi: 10.1039/c7nr02363d.

16.

Established and Novel Prognostic Biomarkers in Multiple Myeloma.

Bustoros M, Mouhieddine TH, Detappe A, Ghobrial IM.

Am Soc Clin Oncol Educ Book. 2017;37:548-560. doi: 10.14694/EDBK_175175. Review.

PMID:
28561668
17.

The Mutational Landscape of Circulating Tumor Cells in Multiple Myeloma.

Mishima Y, Paiva B, Shi J, Park J, Manier S, Takagi S, Massoud M, Perilla-Glen A, Aljawai Y, Huynh D, Roccaro AM, Sacco A, Capelletti M, Detappe A, Alignani D, Anderson KC, Munshi NC, Prosper F, Lohr JG, Ha G, Freeman SS, Van Allen EM, Adalsteinsson VA, Michor F, San Miguel JF, Ghobrial IM.

Cell Rep. 2017 Apr 4;19(1):218-224. doi: 10.1016/j.celrep.2017.03.025.

18.

TIRR regulates 53BP1 by masking its histone methyl-lysine binding function.

Drané P, Brault ME, Cui G, Meghani K, Chaubey S, Detappe A, Parnandi N, He Y, Zheng XF, Botuyan MV, Kalousi A, Yewdell WT, Münch C, Harper JW, Chaudhuri J, Soutoglou E, Mer G, Chowdhury D.

Nature. 2017 Mar 9;543(7644):211-216. doi: 10.1038/nature21358. Epub 2017 Feb 27.

19.

Ultrasmall Silica-Based Bismuth Gadolinium Nanoparticles for Dual Magnetic Resonance-Computed Tomography Image Guided Radiation Therapy.

Detappe A, Thomas E, Tibbitt MW, Kunjachan S, Zavidij O, Parnandi N, Reznichenko E, Lux F, Tillement O, Berbeco R.

Nano Lett. 2017 Mar 8;17(3):1733-1740. doi: 10.1021/acs.nanolett.6b05055. Epub 2017 Feb 2.

20.

Key clinical beam parameters for nanoparticle-mediated radiation dose amplification.

Detappe A, Kunjachan S, Drané P, Kotb S, Myronakis M, Biancur DE, Ireland T, Wagar M, Lux F, Tillement O, Berbeco R.

Sci Rep. 2016 Sep 23;6:34040. doi: 10.1038/srep34040.

21.

Advanced multimodal nanoparticles delay tumor progression with clinical radiation therapy.

Detappe A, Kunjachan S, Sancey L, Motto-Ros V, Biancur D, Drane P, Guieze R, Makrigiorgos GM, Tillement O, Langer R, Berbeco R.

J Control Release. 2016 Sep 28;238:103-113. doi: 10.1016/j.jconrel.2016.07.021. Epub 2016 Jul 14.

PMID:
27423325
22.

Stereotactic modulation of blood-brain barrier permeability to enhance drug delivery.

Appelboom G, Detappe A, LoPresti M, Kunjachan S, Mitrasinovic S, Goldman S, Chang SD, Tillement O.

Neuro Oncol. 2016 Dec;18(12):1601-1609. Epub 2016 Jul 11. Review.

23.

Pushing radiation therapy limitations with theranostic nanoparticles.

Detappe A, Lux F, Tillement O.

Nanomedicine (Lond). 2016 May;11(9):997-9. doi: 10.2217/nnm.16.38. Epub 2016 Apr 13. No abstract available.

PMID:
27074108
24.

Gadolinium-Based Nanoparticles and Radiation Therapy for Multiple Brain Melanoma Metastases: Proof of Concept before Phase I Trial.

Kotb S, Detappe A, Lux F, Appaix F, Barbier EL, Tran VL, Plissonneau M, Gehan H, Lefranc F, Rodriguez-Lafrasse C, Verry C, Berbeco R, Tillement O, Sancey L.

Theranostics. 2016 Jan 20;6(3):418-27. doi: 10.7150/thno.14018. eCollection 2016.

25.

Focused ultrasound to transiently disrupt the blood brain barrier.

Mitrasinovic S, Appelboom G, Detappe A, Sander Connolly E Jr.

J Clin Neurosci. 2016 Jun;28:187-9. doi: 10.1016/j.jocn.2015.12.011. Epub 2016 Feb 13. No abstract available.

PMID:
26883350
26.

Low Z target switching to increase tumor endothelial cell dose enhancement during gold nanoparticle-aided radiation therapy.

Berbeco RI, Detappe A, Tsiamas P, Parsons D, Yewondwossen M, Robar J.

Med Phys. 2016 Jan;43(1):436. doi: 10.1118/1.4938410.

27.

Nanoparticle Mediated Tumor Vascular Disruption: A Novel Strategy in Radiation Therapy.

Kunjachan S, Detappe A, Kumar R, Ireland T, Cameron L, Biancur DE, Motto-Ros V, Sancey L, Sridhar S, Makrigiorgos GM, Berbeco RI.

Nano Lett. 2015 Nov 11;15(11):7488-96. doi: 10.1021/acs.nanolett.5b03073. Epub 2015 Oct 6.

28.

AGuIX nanoparticles as a promising platform for image-guided radiation therapy.

Detappe A, Kunjachan S, Rottmann J, Robar J, Tsiamas P, Korideck H, Tillement O, Berbeco R.

Cancer Nanotechnol. 2015;6(1):4. Epub 2015 Sep 2.

29.

[Ultrasmall nanoparticles for radiotherapy: AGuIX].

Lux F, Detappe A, Dufort S, Sancey L, Louis C, Carme S, Tillement O.

Cancer Radiother. 2015 Oct;19(6-7):508-14. doi: 10.1016/j.canrad.2015.05.019. Epub 2015 Sep 3. Review. French.

PMID:
26343033
30.

New potential for enhancing concomitant chemoradiotherapy with FDA approved concentrations of cisplatin via the photoelectric effect.

Altundal Y, Cifter G, Detappe A, Sajo E, Tsiamas P, Zygmanski P, Berbeco R, Cormack RA, Makrigiorgos M, Ngwa W.

Phys Med. 2015 Feb;31(1):25-30. doi: 10.1016/j.ejmp.2014.11.004. Epub 2014 Dec 6.

31.

The use of theranostic gadolinium-based nanoprobes to improve radiotherapy efficacy.

Sancey L, Lux F, Kotb S, Roux S, Dufort S, Bianchi A, Crémillieux Y, Fries P, Coll JL, Rodriguez-Lafrasse C, Janier M, Dutreix M, Barberi-Heyob M, Boschetti F, Denat F, Louis C, Porcel E, Lacombe S, Le Duc G, Deutsch E, Perfettini JL, Detappe A, Verry C, Berbeco R, Butterworth KT, McMahon SJ, Prise KM, Perriat P, Tillement O.

Br J Radiol. 2014 Sep;87(1041):20140134. doi: 10.1259/bjr.20140134. Epub 2014 Jul 3. Review.

32.

The effect of flattening filter free delivery on endothelial dose enhancement with gold nanoparticles.

Detappe A, Tsiamas P, Ngwa W, Zygmanski P, Makrigiorgos M, Berbeco R.

Med Phys. 2013 Mar;40(3):031706. doi: 10.1118/1.4791671.

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