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Items: 1 to 50 of 56

1.

Pulmonary sarcomatoid carcinoma presenting both ALK rearrangement and PD-L1 high positivity: A case report on the therapeutic regimen.

D'Antonio F, De Sanctis R, Bolengo I, Destro A, Rahal D, De Vincenzo F, Santoro A.

Medicine (Baltimore). 2019 Aug;98(32):e16754. doi: 10.1097/MD.0000000000016754.

2.

Antitumor Activity of a Novel Fibroblast Growth Factor Receptor Inhibitor for Intrahepatic Cholangiocarcinoma.

Raggi C, Fiaccadori K, Pastore M, Correnti M, Piombanti B, Forti E, Navari N, Abbadessa G, Hall T, Destro A, Di Tommaso L, Roncalli M, Meng F, Glaser S, Rovida E, Peraldo-Neia C, Olaizola P, Banales JM, Gerussi A, Elvevi A, Droz Dit Busset M, Bhoori S, Mazzaferro V, Alpini G, Marra F, Invernizzi P.

Am J Pathol. 2019 Oct;189(10):2090-2101. doi: 10.1016/j.ajpath.2019.06.007. Epub 2019 Jul 24.

PMID:
31351075
3.

Phenotypic and molecular changes in nodule-in-nodule hepatocellular carcinoma with pathogenetic implications.

Rudini N, Novello C, Destro A, Riboldi E, Donadon M, Viganò L, Morenghi E, Roncalli M, Di Tommaso L.

Histopathology. 2018 Oct;73(4):601-611. doi: 10.1111/his.13659. Epub 2018 Jul 20.

PMID:
29791027
4.

Emergence of KRAS-mutation in liver metastases after an anti-EGFR treatment in patient with colorectal cancer: Are we aware of the therapeutic impact of intratumor heterogeneity?

Baretti M, Personeni N, Destro A, Santoro A, Rimassa L.

Cancer Biol Ther. 2018 Aug 3;19(8):659-663. doi: 10.1080/15384047.2018.1450117. Epub 2018 Apr 13.

5.

Phase II Study of Everolimus in Patients With Thymoma and Thymic Carcinoma Previously Treated With Cisplatin-Based Chemotherapy.

Zucali PA, De Pas T, Palmieri G, Favaretto A, Chella A, Tiseo M, Caruso M, Simonelli M, Perrino M, De Vincenzo F, Toffalorio F, Damiano V, Pasello G, Garbella E, Ali M, Conforti F, Ottaviano M, Cioffi A, De Placido S, Giordano L, Bertossi M, Destro A, Di Tommaso L, Santoro A.

J Clin Oncol. 2018 Feb 1;36(4):342-349. doi: 10.1200/JCO.2017.74.4078. Epub 2017 Dec 14.

PMID:
29240542
6.

Cholangiocarcinoma stem-like subset shapes tumor-initiating niche by educating associated macrophages.

Raggi C, Correnti M, Sica A, Andersen JB, Cardinale V, Alvaro D, Chiorino G, Forti E, Glaser S, Alpini G, Destro A, Sozio F, Di Tommaso L, Roncalli M, Banales JM, Coulouarn C, Bujanda L, Torzilli G, Invernizzi P.

J Hepatol. 2017 Jan;66(1):102-115. doi: 10.1016/j.jhep.2016.08.012. Epub 2016 Sep 1.

7.

Specific patterns of PIWI-interacting small noncoding RNA expression in dysplastic liver nodules and hepatocellular carcinoma.

Rizzo F, Rinaldi A, Marchese G, Coviello E, Sellitto A, Cordella A, Giurato G, Nassa G, Ravo M, Tarallo R, Milanesi L, Destro A, Torzilli G, Roncalli M, Di Tommaso L, Weisz A.

Oncotarget. 2016 Aug 23;7(34):54650-54661. doi: 10.18632/oncotarget.10567.

8.

Morphophenotypic changes in human multistep hepatocarcinogenesis with translational implications.

Sciarra A, Di Tommaso L, Nakano M, Destro A, Torzilli G, Donadon M, Maggioni M, Bosari S, Bulfamante G, Matsuda M, Fujii H, Ichikawa T, Morisaka H, Sano K, Ichikawa S, Roncalli M.

J Hepatol. 2016 Jan;64(1):87-93. doi: 10.1016/j.jhep.2015.08.031. Epub 2015 Sep 5.

9.

FOLFIRI and Cetuximab Every Second Week for First-Line Treatment of KRAS Wild-Type Metastatic Colorectal Cancer According to Phosphatase and Tensin Homolog Expression: A Phase II Study.

Personeni N, Rimassa L, Verusio C, Barni S, Rubino L, Bozzarelli S, Villa E, Carnaghi C, Tronconi MC, Gerardi C, Galli F, Floriani I, Destro A, Raschioni C, Labianca R, Santoro A.

Clin Colorectal Cancer. 2015 Sep;14(3):162-9. doi: 10.1016/j.clcc.2015.02.006. Epub 2015 Mar 6.

PMID:
25861836
10.

Long-Term Follow-up Results of the DANTE Trial, a Randomized Study of Lung Cancer Screening with Spiral Computed Tomography.

Infante M, Cavuto S, Lutman FR, Passera E, Chiarenza M, Chiesa G, Brambilla G, Angeli E, Aranzulla G, Chiti A, Scorsetti M, Navarria P, Cavina R, Ciccarelli M, Roncalli M, Destro A, Bottoni E, Voulaz E, Errico V, Ferraroli G, Finocchiaro G, Toschi L, Santoro A, Alloisio M; DANTE Study Group.

Am J Respir Crit Care Med. 2015 May 15;191(10):1166-75. doi: 10.1164/rccm.201408-1475OC.

PMID:
25760561
11.

An exploratory biomarker study in metastatic tumors from colorectal cancer patients treated with bevacizumab.

Sclafani F, Rimassa L, Colombo P, Destro A, Stinco S, Lutman FR, Carnaghi C, Beretta G, Zanello A, Roncalli M, Giordano L, Santoro A.

Int J Biol Markers. 2015 Feb 24;30(1):e73-80. doi: 10.5301/jbm.5000097.

PMID:
24980447
12.

Combined hepatocellular carcinoma - cholangiocarcinoma harboring a metastasis of colon adenocarcinoma.

Pintea B, Di Tommaso L, Destro A, Roncalli M.

J Gastrointestin Liver Dis. 2013 Sep;22(3):341-3.

13.

Immunohistohemical expression of the chemokine fractalkine and its receptor in the human brain cortex after severe traumatic brain injury and brain hemorrhage.

Gaetani P, Pisano P, Solinas G, Colombo P, Destro A, Levi D, Aimar E, Rodriguez R, Baena Y, Allavena P.

J Neurosurg Sci. 2013 Mar;57(1):55-62.

PMID:
23584220
14.

Molecular determinants of outcome in sorafenib-treated patients with hepatocellular carcinoma.

Personeni N, Rimassa L, Pressiani T, Destro A, Ligorio C, Tronconi MC, Bozzarelli S, Carnaghi C, Di Tommaso L, Giordano L, Roncalli M, Santoro A.

J Cancer Res Clin Oncol. 2013 Jul;139(7):1179-87. doi: 10.1007/s00432-013-1429-x. Epub 2013 Apr 9.

PMID:
23568548
15.

Genetic and epigenetic alterations in primary colorectal cancers and related lymph node and liver metastases.

Miranda E, Bianchi P, Destro A, Morenghi E, Malesci A, Santoro A, Laghi L, Roncalli M.

Cancer. 2013 Jan 15;119(2):266-76. doi: 10.1002/cncr.27722. Epub 2012 Jul 11.

16.

MicroRNA profiling of hepatocarcinogenesis identifies C19MC cluster as a novel prognostic biomarker in hepatocellular carcinoma.

Augello C, Vaira V, Caruso L, Destro A, Maggioni M, Park YN, Montorsi M, Santambrogio R, Roncalli M, Bosari S.

Liver Int. 2012 May;32(5):772-82. doi: 10.1111/j.1478-3231.2012.02795.x. Epub 2012 Mar 19.

PMID:
22429613
17.

p95HER2 truncated form in resected non-small cell lung cancer.

Cappuzzo F, Cho YG, Sacconi A, Alì G, Siclari O, Incarbone M, Destro A, Terracciano L, Fontanini G, Marchetti A, Roncalli M, Varella-Garcia M.

J Thorac Oncol. 2012 Mar;7(3):520-7. doi: 10.1097/JTO.0b013e318249e13f. Erratum in: J Thorac Oncol. 2012 Jun;7(6):1065.

18.

Detection of somatostatin receptor subtypes 2 and 5 by somatostatin receptor scintigraphy and immunohistochemistry: clinical implications in the diagnostic and therapeutic management of gastroenteropancreatic neuroendocrine tumors.

Sclafani F, Carnaghi C, Di Tommaso L, Rodari M, Destro A, Rimassa L, Giordano L, Chiti A, Roncalli M, Santoro A.

Tumori. 2011 Sep-Oct;97(5):620-8. doi: 10.1700/989.10722.

PMID:
22158494
19.

Preclinical emergence of vandetanib as a potent antitumour agent in mesothelioma: molecular mechanisms underlying its synergistic interaction with pemetrexed and carboplatin.

Giovannetti E, Zucali PA, Assaraf YG, Leon LG, Smid K, Alecci C, Giancola F, Destro A, Gianoncelli L, Lorenzi E, Roncalli M, Santoro A, Peters GJ.

Br J Cancer. 2011 Nov 8;105(10):1542-53. doi: 10.1038/bjc.2011.400. Epub 2011 Oct 4.

20.

Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab.

Yonesaka K, Zejnullahu K, Okamoto I, Satoh T, Cappuzzo F, Souglakos J, Ercan D, Rogers A, Roncalli M, Takeda M, Fujisaka Y, Philips J, Shimizu T, Maenishi O, Cho Y, Sun J, Destro A, Taira K, Takeda K, Okabe T, Swanson J, Itoh H, Takada M, Lifshits E, Okuno K, Engelman JA, Shivdasani RA, Nishio K, Fukuoka M, Varella-Garcia M, Nakagawa K, Jänne PA.

Sci Transl Med. 2011 Sep 7;3(99):99ra86. doi: 10.1126/scitranslmed.3002442.

21.

The critical role of agrin in the hematopoietic stem cell niche.

Mazzon C, Anselmo A, Cibella J, Soldani C, Destro A, Kim N, Roncalli M, Burden SJ, Dustin ML, Sarukhan A, Viola A.

Blood. 2011 Sep 8;118(10):2733-42. doi: 10.1182/blood-2011-01-331272. Epub 2011 Jun 7.

22.

Diagnostic accuracy of clathrin heavy chain staining in a marker panel for the diagnosis of small hepatocellular carcinoma.

Di Tommaso L, Destro A, Fabbris V, Spagnuolo G, Laura Fracanzani A, Fargion S, Maggioni M, Patriarca C, Maria Macchi R, Quagliuolo M, Borzio M, Iavarone M, Sangiovanni A, Colombo M, Roncalli M.

Hepatology. 2011 May;53(5):1549-57. doi: 10.1002/hep.24218.

PMID:
21520170
23.

Abl interconnects oncogenic Met and p53 core pathways in cancer cells.

Furlan A, Stagni V, Hussain A, Richelme S, Conti F, Prodosmo A, Destro A, Roncalli M, Barilà D, Maina F.

Cell Death Differ. 2011 Oct;18(10):1608-16. doi: 10.1038/cdd.2011.23. Epub 2011 Apr 1.

24.

Thymidylate synthase and excision repair cross-complementing group-1 as predictors of responsiveness in mesothelioma patients treated with pemetrexed/carboplatin.

Zucali PA, Giovannetti E, Destro A, Mencoboni M, Ceresoli GL, Gianoncelli L, Lorenzi E, De Vincenzo F, Simonelli M, Perrino M, Bruzzone A, Thunnissen E, Tunesi G, Giordano L, Roncalli M, Peters GJ, Santoro A.

Clin Cancer Res. 2011 Apr 15;17(8):2581-90. doi: 10.1158/1078-0432.CCR-10-2873. Epub 2011 Jan 24.

25.

A 3-D study of capsular invasion in follicular thyroid tumors. A novel approach to an old dilemma.

Di Tommaso L, Tresoldi D, Navligu CI, Destro A, Comi P, Morbiducci U, Roncalli M, Rizzo G.

Pathologica. 2010 Jun;102(3):93-5.

PMID:
21171511
26.

Cracking spaces in Hashimoto Thyroiditis are lymphatic and prelymphatic vessels: a gift of immunohistochemistry for the centenary of Hashimoto's description.

Di Tommaso L, Battista S, Destro A, Sciarra A, Morenghi E, Roncalli M.

Am J Surg Pathol. 2010 Dec;34(12):1857-61. doi: 10.1097/PAS.0b013e3181fb40fa. Erratum in: Am J Surg Pathol. 2011 Feb;35(2):314.

PMID:
21107092
27.

Human glioblastoma tumours and neural cancer stem cells express the chemokine CX3CL1 and its receptor CX3CR1.

Erreni M, Solinas G, Brescia P, Osti D, Zunino F, Colombo P, Destro A, Roncalli M, Mantovani A, Draghi R, Levi D, Rodriguez Y Baena R, Gaetani P, Pelicci G, Allavena P.

Eur J Cancer. 2010 Dec;46(18):3383-92. doi: 10.1016/j.ejca.2010.07.022. Epub 2010 Aug 19.

PMID:
20728344
28.

A randomized study of lung cancer screening with spiral computed tomography: three-year results from the DANTE trial.

Infante M, Cavuto S, Lutman FR, Brambilla G, Chiesa G, Ceresoli G, Passera E, Angeli E, Chiarenza M, Aranzulla G, Cariboni U, Errico V, Inzirillo F, Bottoni E, Voulaz E, Alloisio M, Destro A, Roncalli M, Santoro A, Ravasi G; DANTE Study Group.

Am J Respir Crit Care Med. 2009 Sep 1;180(5):445-53. doi: 10.1164/rccm.200901-0076OC. Epub 2009 Jun 11.

PMID:
19520905
29.

Increased MET gene copy number negatively affects survival of surgically resected non-small-cell lung cancer patients.

Cappuzzo F, Marchetti A, Skokan M, Rossi E, Gajapathy S, Felicioni L, Del Grammastro M, Sciarrotta MG, Buttitta F, Incarbone M, Toschi L, Finocchiaro G, Destro A, Terracciano L, Roncalli M, Alloisio M, Santoro A, Varella-Garcia M.

J Clin Oncol. 2009 Apr 1;27(10):1667-74. doi: 10.1200/JCO.2008.19.1635. Epub 2009 Mar 2.

30.

The application of markers (HSP70 GPC3 and GS) in liver biopsies is useful for detection of hepatocellular carcinoma.

Di Tommaso L, Destro A, Seok JY, Balladore E, Terracciano L, Sangiovanni A, Iavarone M, Colombo M, Jang JJ, Yu E, Jin SY, Morenghi E, Park YN, Roncalli M.

J Hepatol. 2009 Apr;50(4):746-54. doi: 10.1016/j.jhep.2008.11.014. Epub 2008 Dec 25.

PMID:
19231003
31.

The chemokine receptor CX3CR1 is involved in the neural tropism and malignant behavior of pancreatic ductal adenocarcinoma.

Marchesi F, Piemonti L, Fedele G, Destro A, Roncalli M, Albarello L, Doglioni C, Anselmo A, Doni A, Bianchi P, Laghi L, Malesci A, Cervo L, Malosio M, Reni M, Zerbi A, Di Carlo V, Mantovani A, Allavena P.

Cancer Res. 2008 Nov 1;68(21):9060-9. doi: 10.1158/0008-5472.CAN-08-1810.

32.

MET increased gene copy number and primary resistance to gefitinib therapy in non-small-cell lung cancer patients.

Cappuzzo F, Jänne PA, Skokan M, Finocchiaro G, Rossi E, Ligorio C, Zucali PA, Terracciano L, Toschi L, Roncalli M, Destro A, Incarbone M, Alloisio M, Santoro A, Varella-Garcia M.

Ann Oncol. 2009 Feb;20(2):298-304. doi: 10.1093/annonc/mdn635. Epub 2008 Oct 3.

33.

Toker cells of the breast. Morphological and immunohistochemical characterization of 40 cases.

Di Tommaso L, Franchi G, Destro A, Broglia F, Minuti F, Rahal D, Roncalli M.

Hum Pathol. 2008 Sep;39(9):1295-300. doi: 10.1016/j.humpath.2008.01.018. Epub 2008 Jul 9.

PMID:
18614197
34.

Primary resistance to cetuximab therapy in EGFR FISH-positive colorectal cancer patients.

Cappuzzo F, Varella-Garcia M, Finocchiaro G, Skokan M, Gajapathy S, Carnaghi C, Rimassa L, Rossi E, Ligorio C, Di Tommaso L, Holmes AJ, Toschi L, Tallini G, Destro A, Roncalli M, Santoro A, Jänne PA.

Br J Cancer. 2008 Jul 8;99(1):83-9. doi: 10.1038/sj.bjc.6604439. Epub 2008 Jun 24.

35.

Role of cMET expression in non-small-cell lung cancer patients treated with EGFR tyrosine kinase inhibitors.

Zucali PA, Ruiz MG, Giovannetti E, Destro A, Varella-Garcia M, Floor K, Ceresoli GL, Rodriguez JA, Garassino I, Comoglio P, Roncalli M, Santoro A, Giaccone G.

Ann Oncol. 2008 Sep;19(9):1605-12. doi: 10.1093/annonc/mdn240. Epub 2008 May 7.

PMID:
18467317
36.

Molecular alterations in spontaneous sputum of cancer-free heavy smokers: results from a large screening program.

Baryshnikova E, Destro A, Infante MV, Cavuto S, Cariboni U, Alloisio M, Ceresoli GL, Lutman R, Brambilla G, Chiesa G, Ravasi G, Roncalli M.

Clin Cancer Res. 2008 Mar 15;14(6):1913-9. doi: 10.1158/1078-0432.CCR-07-1741.

37.

EGFR FISH assay predicts for response to cetuximab in chemotherapy refractory colorectal cancer patients.

Cappuzzo F, Finocchiaro G, Rossi E, Jänne PA, Carnaghi C, Calandri C, Bencardino K, Ligorio C, Ciardiello F, Pressiani T, Destro A, Roncalli M, Crino L, Franklin WA, Santoro A, Varella-Garcia M.

Ann Oncol. 2008 Apr;19(4):717-23. Epub 2007 Oct 31.

PMID:
17974556
38.

Lung cancer screening with spiral CT: baseline results of the randomized DANTE trial.

Infante M, Lutman FR, Cavuto S, Brambilla G, Chiesa G, Passera E, Angeli E, Chiarenza M, Aranzulla G, Cariboni U, Alloisio M, Incarbone M, Testori A, Destro A, Cappuzzo F, Roncalli M, Santoro A, Ravasi G; DANTE Study Group.

Lung Cancer. 2008 Mar;59(3):355-63. Epub 2007 Oct 23.

PMID:
17936405
39.

Gene methylation in pleural mesothelioma: correlations with clinico-pathological features and patient's follow-up.

Destro A, Ceresoli GL, Baryshnikova E, Garassino I, Zucali PA, De Vincenzo F, Bianchi P, Morenghi E, Testori A, Alloisio M, Santoro A, Roncalli M.

Lung Cancer. 2008 Mar;59(3):369-76. Epub 2007 Oct 24.

PMID:
17920725
40.

Telomere shortening and inactivation of cell cycle checkpoints characterize human hepatocarcinogenesis.

Plentz RR, Park YN, Lechel A, Kim H, Nellessen F, Langkopf BH, Wilkens L, Destro A, Fiamengo B, Manns MP, Roncalli M, Rudolph KL.

Hepatology. 2007 Apr;45(4):968-76.

PMID:
17393506
41.

Diagnostic value of HSP70, glypican 3, and glutamine synthetase in hepatocellular nodules in cirrhosis.

Di Tommaso L, Franchi G, Park YN, Fiamengo B, Destro A, Morenghi E, Montorsi M, Torzilli G, Tommasini M, Terracciano L, Tornillo L, Vecchione R, Roncalli M.

Hepatology. 2007 Mar;45(3):725-34.

PMID:
17326147
42.

Genetic and epigenetic changes in primary metastatic and nonmetastatic colorectal cancer.

Miranda E, Destro A, Malesci A, Balladore E, Bianchi P, Baryshnikova E, Franchi G, Morenghi E, Laghi L, Gennari L, Roncalli M.

Br J Cancer. 2006 Oct 23;95(8):1101-7. Epub 2006 Sep 12.

43.

Anatomic location of breast cancer micrometastasis in sentinel lymph node predicts axillary status.

Di Tommaso L, Arizzi C, Rahal D, Destro A, Roncalli M, Alloisio M, Orefice S, Rubino A, Morenghi E, Masci G, Santoro A, Del Prato I, Sacco R.

Ann Surg. 2006 May;243(5):706-7; author reply 706-7. No abstract available.

44.

Quantitative evaluation of RASSF1A methylation in the non-lesional, regenerative and neoplastic liver.

Di Gioia S, Bianchi P, Destro A, Grizzi F, Malesci A, Laghi L, Levrero M, Morabito A, Roncalli M.

BMC Cancer. 2006 Apr 10;6:89.

45.

EGFR overexpression in malignant pleural mesothelioma. An immunohistochemical and molecular study with clinico-pathological correlations.

Destro A, Ceresoli GL, Falleni M, Zucali PA, Morenghi E, Bianchi P, Pellegrini C, Cordani N, Vaira V, Alloisio M, Rizzi A, Bosari S, Roncalli M.

Lung Cancer. 2006 Feb;51(2):207-15. Epub 2005 Dec 27.

PMID:
16384623
46.

Modular structure of the human lamin B2 replicator.

Paixão S, Colaluca IN, Cubells M, Peverali FA, Destro A, Giadrossi S, Giacca M, Falaschi A, Riva S, Biamonti G.

Mol Cell Biol. 2004 Apr;24(7):2958-67.

47.

K-ras and p16(INK4A)alterations in sputum of NSCLC patients and in heavy asymptomatic chronic smokers.

Destro A, Bianchi P, Alloisio M, Laghi L, Di Gioia S, Malesci A, Cariboni U, Gribaudi G, Bulfamante G, Marchetti A, Bosari S, Infante M, Ravasi G, Roncalli M.

Lung Cancer. 2004 Apr;44(1):23-32.

PMID:
15013580
48.

Methylation framework of cell cycle gene inhibitors in cirrhosis and associated hepatocellular carcinoma.

Roncalli M, Bianchi P, Bruni B, Laghi L, Destro A, Di Gioia S, Gennari L, Tommasini M, Malesci A, Coggi G.

Hepatology. 2002 Aug;36(2):427-32.

PMID:
12143052
49.

Induction of antibodies against GM2 ganglioside by immunizing melanoma patients using GM2-keyhole limpet hemocyanin + QS21 vaccine: a dose-response study.

Chapman PB, Morrissey DM, Panageas KS, Hamilton WB, Zhan C, Destro AN, Williams L, Israel RJ, Livingston PO.

Clin Cancer Res. 2000 Mar;6(3):874-9.

50.

Phase III multicenter randomized trial of the Dartmouth regimen versus dacarbazine in patients with metastatic melanoma.

Chapman PB, Einhorn LH, Meyers ML, Saxman S, Destro AN, Panageas KS, Begg CB, Agarwala SS, Schuchter LM, Ernstoff MS, Houghton AN, Kirkwood JM.

J Clin Oncol. 1999 Sep;17(9):2745-51.

PMID:
10561349

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