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Items: 1 to 50 of 114

1.

Brief O2 uploading during continuous hypothermic machine perfusion is simple yet effective oxygenation method to improve initial kidney function in a porcine autotransplant model.

Darius T, Vergauwen M, Smith T, Gerin I, Joris V, Mueller M, Aydin S, Muller X, Schlegel A, Nath J, Ludwig C, Dessy C, Many MC, Bommer G, Dutkowski P, Gianello P, Mourad M.

Am J Transplant. 2020 Feb 3. doi: 10.1111/ajt.15800. [Epub ahead of print]

PMID:
32012434
2.

TGFβ2-induced formation of lipid droplets supports acidosis-driven EMT and the metastatic spreading of cancer cells.

Corbet C, Bastien E, Santiago de Jesus JP, Dierge E, Martherus R, Vander Linden C, Doix B, Degavre C, Guilbaud C, Petit L, Michiels C, Dessy C, Larondelle Y, Feron O.

Nat Commun. 2020 Jan 23;11(1):454. doi: 10.1038/s41467-019-14262-3.

3.

Influence of different partial pressures of oxygen during continuous hypothermic machine perfusion in a pig kidney ischemia-reperfusion autotransplant model.

Darius T, Vergauwen M, Smith TB, Patel K, Craps J, Joris V, Aydin S, Ury B, Buemi A, De Meyer M, Nath J, Ludwig C, Dessy C, Many MC, Gianello P, Mourad M.

Transplantation. 2019 Nov 15. doi: 10.1097/TP.0000000000003051. [Epub ahead of print]

PMID:
31764761
4.

Chitin-glucan and pomegranate polyphenols improve endothelial dysfunction.

Neyrinck AM, Catry E, Taminiau B, Cani PD, Bindels LB, Daube G, Dessy C, Delzenne NM.

Sci Rep. 2019 Oct 2;9(1):14150. doi: 10.1038/s41598-019-50700-4.

5.

MicroRNA-199a-3p and MicroRNA-199a-5p Take Part to a Redundant Network of Regulation of the NOS (NO Synthase)/NO Pathway in the Endothelium.

Joris V, Gomez EL, Menchi L, Lobysheva I, Di Mauro V, Esfahani H, Condorelli G, Balligand JL, Catalucci D, Dessy C.

Arterioscler Thromb Vasc Biol. 2018 Oct;38(10):2345-2357. doi: 10.1161/ATVBAHA.118.311145.

PMID:
29976767
6.

Perfusion-decellularization of human ear grafts enables ECM-based scaffolds for auricular vascularized composite tissue engineering.

Duisit J, Amiel H, Wüthrich T, Taddeo A, Dedriche A, Destoop V, Pardoen T, Bouzin C, Joris V, Magee D, Vögelin E, Harriman D, Dessy C, Orlando G, Behets C, Rieben R, Gianello P, Lengelé B.

Acta Biomater. 2018 Jun;73:339-354. doi: 10.1016/j.actbio.2018.04.009. Epub 2018 Apr 11.

7.

Bioengineering a Human Face Graft: The Matrix of Identity.

Duisit J, Maistriaux L, Taddeo A, Orlando G, Joris V, Coche E, Behets C, Lerut J, Dessy C, Cossu G, Vögelin E, Rieben R, Gianello P, Lengelé B.

Ann Surg. 2017 Nov;266(5):754-764. doi: 10.1097/SLA.0000000000002396.

8.

Targeting the gut microbiota with inulin-type fructans: preclinical demonstration of a novel approach in the management of endothelial dysfunction.

Catry E, Bindels LB, Tailleux A, Lestavel S, Neyrinck AM, Goossens JF, Lobysheva I, Plovier H, Essaghir A, Demoulin JB, Bouzin C, Pachikian BD, Cani PD, Staels B, Dessy C, Delzenne NM.

Gut. 2018 Feb;67(2):271-283. doi: 10.1136/gutjnl-2016-313316. Epub 2017 Apr 4.

9.

MRI Assessment of Cardiomyopathy Induced by β1-Adrenoreceptor Autoantibodies and Protection Through β3-Adrenoreceptor Overexpression.

Vanhoutte L, Guilbaud C, Martherus R, Bouzin C, Gallez B, Dessy C, Balligand JL, Moniotte S, Feron O.

Sci Rep. 2017 Mar 9;7:43951. doi: 10.1038/srep43951.

10.

Hyaluronidase 1 Deficiency Preserves Endothelial Function and Glycocalyx Integrity in Early Streptozotocin-Induced Diabetes.

Dogné S, Rath G, Jouret F, Caron N, Dessy C, Flamion B.

Diabetes. 2016 Sep;65(9):2742-53. doi: 10.2337/db15-1662. Epub 2016 May 31.

11.

Vascular and Central Activation of Peroxisome Proliferator-Activated Receptor-β Attenuates Angiotensin II-Induced Hypertension: Role of RGS-5.

Romero M, Jiménez R, Toral M, León-Gómez E, Gómez-Gúzman M, Sánchez M, Zarzuelo MJ, Rodríguez-Gómez I, Rath G, Tamargo J, Pérez-Vizcaíno F, Dessy C, Duarte J.

J Pharmacol Exp Ther. 2016 Jul;358(1):151-63. doi: 10.1124/jpet.116.233106. Epub 2016 Apr 27.

PMID:
27189971
12.

Nutritional depletion in n-3 PUFA in apoE knock-out mice: A new model of endothelial dysfunction associated with fatty liver disease.

Catry E, Neyrinck AM, Lobysheva I, Pachikian BD, Van Hul M, Cani PD, Dessy C, Delzenne NM.

Mol Nutr Food Res. 2016 Oct;60(10):2198-2207. doi: 10.1002/mnfr.201500930. Epub 2016 Jun 1.

PMID:
27136390
13.

Effects of BM-573 on Endothelial Dependent Relaxation and Increased Blood Pressure at Early Stages of Atherosclerosis.

Romero M, Leon-Gomez E, Lobysheva I, Rath G, Dogné JM, Feron O, Dessy C.

PLoS One. 2016 Mar 28;11(3):e0152579. doi: 10.1371/journal.pone.0152579. eCollection 2016.

14.

Vascular Endothelium-Dependent and Independent Actions of Oleanolic Acid and Its Synthetic Oleanane Derivatives as Possible Mechanisms for Hypotensive Effects.

Madlala HP, Metzinger T, van Heerden FR, Musabayane CT, Mubagwa K, Dessy C.

PLoS One. 2016 Jan 22;11(1):e0147395. doi: 10.1371/journal.pone.0147395. eCollection 2016.

15.

A new ER-specific photosensitizer unravels (1)O2-driven protein oxidation and inhibition of deubiquitinases as a generic mechanism for cancer PDT.

Pinto A, Mace Y, Drouet F, Bony E, Boidot R, Draoui N, Lobysheva I, Corbet C, Polet F, Martherus R, Deraedt Q, Rodríguez J, Lamy C, Schicke O, Delvaux D, Louis C, Kiss R, Kriegsheim AV, Dessy C, Elias B, Quetin-Leclercq J, Riant O, Feron O.

Oncogene. 2016 Jul 28;35(30):3976-85. doi: 10.1038/onc.2015.474. Epub 2015 Dec 21.

PMID:
26686091
16.

Loss of mouse P2Y4 nucleotide receptor protects against myocardial infarction through endothelin-1 downregulation.

Horckmans M, Esfahani H, Beauloye C, Clouet S, di Pietrantonio L, Robaye B, Balligand JL, Boeynaems JM, Dessy C, Communi D.

J Immunol. 2015 Feb 15;194(4):1874-81. doi: 10.4049/jimmunol.1401364. Epub 2015 Jan 16.

17.

Regulation of calcium channels in smooth muscle: new insights into the role of myosin light chain kinase.

Martinsen A, Dessy C, Morel N.

Channels (Austin). 2014;8(5):402-13. doi: 10.4161/19336950.2014.950537. Review.

18.

AMPK activation by glucagon-like peptide-1 prevents NADPH oxidase activation induced by hyperglycemia in adult cardiomyocytes.

Balteau M, Van Steenbergen A, Timmermans AD, Dessy C, Behets-Wydemans G, Tajeddine N, Castanares-Zapatero D, Gilon P, Vanoverschelde JL, Horman S, Hue L, Bertrand L, Beauloye C.

Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1120-33. doi: 10.1152/ajpheart.00210.2014. Epub 2014 Aug 15.

19.

Enhanced expression of β3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthase.

Belge C, Hammond J, Dubois-Deruy E, Manoury B, Hamelet J, Beauloye C, Markl A, Pouleur AC, Bertrand L, Esfahani H, Jnaoui K, Götz KR, Nikolaev VO, Vanderper A, Herijgers P, Lobysheva I, Iaccarino G, Hilfiker-Kleiner D, Tavernier G, Langin D, Dessy C, Balligand JL.

Circulation. 2014 Jan 28;129(4):451-62. doi: 10.1161/CIRCULATIONAHA.113.004940. Epub 2013 Nov 4.

PMID:
24190960
20.

Myosin light chain kinase controls voltage-dependent calcium channels in vascular smooth muscle.

Martinsen A, Schakman O, Yerna X, Dessy C, Morel N.

Pflugers Arch. 2014 Jul;466(7):1377-89. doi: 10.1007/s00424-013-1380-3. Epub 2013 Oct 27.

PMID:
24162233
21.

Genetic deletion of aquaporin-1 results in microcardia and low blood pressure in mouse with intact nitric oxide-dependent relaxation, but enhanced prostanoids-dependent relaxation.

Montiel V, Leon Gomez E, Bouzin C, Esfahani H, Romero Perez M, Lobysheva I, Devuyst O, Dessy C, Balligand JL.

Pflugers Arch. 2014 Feb;466(2):237-51. doi: 10.1007/s00424-013-1325-x. Epub 2013 Jul 20.

PMID:
23873354
22.

Different effect of Rho kinase inhibition on calcium signaling in rat isolated large and small arteries.

Martinsen A, Yerna X, Rath G, Gomez EL, Dessy C, Morel N.

J Vasc Res. 2012;49(6):522-33. doi: 10.1159/000341230. Epub 2012 Sep 1.

23.

Gene deletion of P2Y4 receptor lowers exercise capacity and reduces myocardial hypertrophy with swimming exercise.

Horckmans M, Léon-Gómez E, Robaye B, Balligand JL, Boeynaems JM, Dessy C, Communi D.

Am J Physiol Heart Circ Physiol. 2012 Oct 1;303(7):H835-43. doi: 10.1152/ajpheart.00256.2012. Epub 2012 Aug 3.

24.

Vascular hypoxic preconditioning relies on TRPV4-dependent calcium influx and proper intercellular gap junctions communication.

Rath G, Saliez J, Behets G, Romero-Perez M, Leon-Gomez E, Bouzin C, Vriens J, Nilius B, Feron O, Dessy C.

Arterioscler Thromb Vasc Biol. 2012 Sep;32(9):2241-9. doi: 10.1161/ATVBAHA.112.252783. Epub 2012 Jul 19.

PMID:
22814746
25.

Rational design of a fluorescent NADPH derivative imaging constitutive nitric-oxide synthases upon two-photon excitation.

Li Y, Wang H, Tarus B, Perez MR, Morellato L, Henry E, Berka V, Tsai AL, Ramassamy B, Dhimane H, Dessy C, Tauc P, Boucher JL, Deprez E, Slama-Schwok A.

Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12526-31. doi: 10.1073/pnas.1205645109. Epub 2012 Jul 16.

26.

Vasodilatory mechanisms of beta receptor blockade.

Rath G, Balligand JL, Dessy C.

Curr Hypertens Rep. 2012 Aug;14(4):310-7. doi: 10.1007/s11906-012-0278-3. Review. Erratum in: Curr Hypertens Rep. 2012 Oct;14(5):473. Chantal, Dessy [corrected to Dessy, Chantal].

PMID:
22639015
27.

P2Y(4) nucleotide receptor: a novel actor in post-natal cardiac development.

Horckmans M, Robaye B, Léon-Gόmez E, Lantz N, Unger P, Dol-Gleizes F, Clouet S, Cammarata D, Schaeffer P, Savi P, Gachet C, Balligand JL, Dessy C, Boeynaems JM, Communi D.

Angiogenesis. 2012 Sep;15(3):349-60. doi: 10.1007/s10456-012-9265-1. Epub 2012 Mar 22.

PMID:
22437266
28.

Regulation of monocarboxylate transporter MCT1 expression by p53 mediates inward and outward lactate fluxes in tumors.

Boidot R, Végran F, Meulle A, Le Breton A, Dessy C, Sonveaux P, Lizard-Nacol S, Feron O.

Cancer Res. 2012 Feb 15;72(4):939-48. doi: 10.1158/0008-5472.CAN-11-2474. Epub 2011 Dec 19.

29.

Moderate caveolin-1 downregulation prevents NADPH oxidase-dependent endothelial nitric oxide synthase uncoupling by angiotensin II in endothelial cells.

Lobysheva I, Rath G, Sekkali B, Bouzin C, Feron O, Gallez B, Dessy C, Balligand JL.

Arterioscler Thromb Vasc Biol. 2011 Sep;31(9):2098-105. doi: 10.1161/ATVBAHA.111.230623. Epub 2011 Jun 9.

PMID:
21659644
30.

Delivery of soluble VEGF receptor 1 (sFlt1) by gene electrotransfer as a new antiangiogenic cancer therapy.

Verrax J, Defresne F, Lair F, Vandermeulen G, Rath G, Dessy C, Préat V, Feron O.

Mol Pharm. 2011 Jun 6;8(3):701-8. doi: 10.1021/mp100268t. Epub 2011 May 13.

PMID:
21548585
31.

Role of G(i/o)-Src kinase-PI3K/Akt pathway and caveolin-1 in β₂-adrenoceptor coupling to endothelial NO synthase in mouse pulmonary artery.

Banquet S, Delannoy E, Agouni A, Dessy C, Lacomme S, Hubert F, Richard V, Muller B, Leblais V.

Cell Signal. 2011 Jul;23(7):1136-43. doi: 10.1016/j.cellsig.2011.02.008. Epub 2011 Mar 6.

PMID:
21385608
32.

Nebivolol exerts beneficial effects on endothelial function, early endothelial progenitor cells, myocardial neovascularization, and left ventricular dysfunction early after myocardial infarction beyond conventional β1-blockade.

Sorrentino SA, Doerries C, Manes C, Speer T, Dessy C, Lobysheva I, Mohmand W, Akbar R, Bahlmann F, Besler C, Schaefer A, Hilfiker-Kleiner D, Lüscher TF, Balligand JL, Drexler H, Landmesser U.

J Am Coll Cardiol. 2011 Feb 1;57(5):601-11. doi: 10.1016/j.jacc.2010.09.037.

33.

Beta3-adrenergic receptors in cardiac and vascular tissues emerging concepts and therapeutic perspectives.

Dessy C, Balligand JL.

Adv Pharmacol. 2010;59:135-63. doi: 10.1016/S1054-3589(10)59005-7. Review.

PMID:
20933201
34.

The regulation of endothelial nitric oxide synthase by caveolin: a paradigm validated in vivo and shared by the 'endothelium-derived hyperpolarizing factor'.

Dessy C, Feron O, Balligand JL.

Pflugers Arch. 2010 May;459(6):817-27. doi: 10.1007/s00424-010-0815-3. Epub 2010 Mar 26. Review.

PMID:
20339866
35.
36.

Ir-CPI, a coagulation contact phase inhibitor from the tick Ixodes ricinus, inhibits thrombus formation without impairing hemostasis.

Decrem Y, Rath G, Blasioli V, Cauchie P, Robert S, Beaufays J, Frère JM, Feron O, Dogné JM, Dessy C, Vanhamme L, Godfroid E.

J Exp Med. 2009 Oct 26;206(11):2381-95. doi: 10.1084/jem.20091007. Epub 2009 Oct 5.

37.

Vascular caveolin deficiency supports the angiogenic effects of nitrite, a major end product of nitric oxide metabolism in tumors.

Frérart F, Lobysheva I, Gallez B, Dessy C, Feron O.

Mol Cancer Res. 2009 Jul;7(7):1056-63. doi: 10.1158/1541-7786.MCR-08-0388. Epub 2009 Jun 30.

38.

Role of caveolin-1 in thyroid phenotype, cell homeostasis, and hormone synthesis: in vivo study of caveolin-1 knockout mice.

Senou M, Costa MJ, Massart C, Thimmesch M, Khalifa C, Poncin S, Boucquey M, Gérard AC, Audinot JN, Dessy C, Ruf J, Feron O, Devuyst O, Guiot Y, Dumont JE, Van Sande J, Many MC.

Am J Physiol Endocrinol Metab. 2009 Aug;297(2):E438-51. doi: 10.1152/ajpendo.90784.2008. Epub 2009 May 12.

39.

eNOS activation by physical forces: from short-term regulation of contraction to chronic remodeling of cardiovascular tissues.

Balligand JL, Feron O, Dessy C.

Physiol Rev. 2009 Apr;89(2):481-534. doi: 10.1152/physrev.00042.2007. Review.

40.

Impact of cyclic hypoxia on HIF-1alpha regulation in endothelial cells--new insights for anti-tumor treatments.

Martinive P, Defresne F, Quaghebeur E, Daneau G, Crokart N, Grégoire V, Gallez B, Dessy C, Feron O.

FEBS J. 2009 Jan;276(2):509-18. doi: 10.1111/j.1742-4658.2008.06798.x. Epub 2008 Dec 10.

41.

The acidic tumor microenvironment promotes the reconversion of nitrite into nitric oxide: towards a new and safe radiosensitizing strategy.

Frérart F, Sonveaux P, Rath G, Smoos A, Meqor A, Charlier N, Jordan BF, Saliez J, Noël A, Dessy C, Gallez B, Feron O.

Clin Cancer Res. 2008 May 1;14(9):2768-74. doi: 10.1158/1078-0432.CCR-07-4001.

42.

Control of blood pressure variability in caveolin-1-deficient mice: role of nitric oxide identified in vivo through spectral analysis.

Desjardins F, Lobysheva I, Pelat M, Gallez B, Feron O, Dessy C, Balligand JL.

Cardiovasc Res. 2008 Aug 1;79(3):527-36. doi: 10.1093/cvr/cvn080. Epub 2008 Mar 18.

PMID:
18349137
43.

The estrogen effects on endothelial repair and mitogen-activated protein kinase activation are abolished in endothelial nitric-oxide (NO) synthase knockout mice, but not by NO synthase inhibition by N-nitro-L-arginine methyl ester.

Billon A, Lehoux S, Lam Shang Leen L, Laurell H, Filipe C, Benouaich V, Brouchet L, Dessy C, Gourdy P, Gadeau AP, Tedgui A, Balligand JL, Arnal JF.

Am J Pathol. 2008 Mar;172(3):830-8. doi: 10.2353/ajpath.2008.070439. Epub 2008 Feb 14.

44.

Role of caveolar compartmentation in endothelium-derived hyperpolarizing factor-mediated relaxation: Ca2+ signals and gap junction function are regulated by caveolin in endothelial cells.

Saliez J, Bouzin C, Rath G, Ghisdal P, Desjardins F, Rezzani R, Rodella LF, Vriens J, Nilius B, Feron O, Balligand JL, Dessy C.

Circulation. 2008 Feb 26;117(8):1065-74. doi: 10.1161/CIRCULATIONAHA.107.731679. Epub 2008 Feb 11.

PMID:
18268148
45.

Sepsis is associated with an upregulation of functional beta3 adrenoceptors in the myocardium.

Moniotte S, Belge C, Sekkali B, Massion PB, Rozec B, Dessy C, Balligand JL.

Eur J Heart Fail. 2007 Dec;9(12):1163-71. Epub 2007 Nov 19.

46.

Caveolin-1 is critical for the maturation of tumor blood vessels through the regulation of both endothelial tube formation and mural cell recruitment.

Dewever J, Frérart F, Bouzin C, Baudelet C, Ansiaux R, Sonveaux P, Gallez B, Dessy C, Feron O.

Am J Pathol. 2007 Nov;171(5):1619-28. Epub 2007 Oct 4.

47.

Reciprocal negative regulation between thyrotropin/3',5'-cyclic adenosine monophosphate-mediated proliferation and caveolin-1 expression in human and murine thyrocytes.

Costa MJ, Senou M, Van Rode F, Ruf J, Capello M, Dequanter D, Lothaire P, Dessy C, Dumont JE, Many MC, Van Sande J.

Mol Endocrinol. 2007 Apr;21(4):921-32. Epub 2007 Jan 3.

PMID:
17202321
48.

Preconditioning of the tumor vasculature and tumor cells by intermittent hypoxia: implications for anticancer therapies.

Martinive P, Defresne F, Bouzin C, Saliez J, Lair F, Grégoire V, Michiels C, Dessy C, Feron O.

Cancer Res. 2006 Dec 15;66(24):11736-44.

49.

The calcium channel blocker amlodipine promotes the unclamping of eNOS from caveolin in endothelial cells.

Batova S, DeWever J, Godfraind T, Balligand JL, Dessy C, Feron O.

Cardiovasc Res. 2006 Aug 1;71(3):478-85. Epub 2006 Apr 27.

PMID:
16814758
50.

Caveolin plays a central role in endothelial progenitor cell mobilization and homing in SDF-1-driven postischemic vasculogenesis.

Sbaa E, Dewever J, Martinive P, Bouzin C, Frérart F, Balligand JL, Dessy C, Feron O.

Circ Res. 2006 May 12;98(9):1219-27. Epub 2006 Apr 6.

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