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Items: 27


Endothelins in inflammatory neurological diseases.

D'Orléans-Juste P, Akide Ndunge OB, Desbiens L, Tanowitz HB, Desruisseaux MS.

Pharmacol Ther. 2019 Feb;194:145-160. doi: 10.1016/j.pharmthera.2018.10.001. Epub 2018 Oct 3. Review.


Trypanosoma cruzi Produces the Specialized Proresolving Mediators Resolvin D1, Resolvin D5, and Resolvin E2.

Colas RA, Ashton AW, Mukherjee S, Dalli J, Akide-Ndunge OB, Huang H, Desruisseaux MS, Guan F, Jelicks LA, Matos Dos Santos F, Nagajyothi J, Zingman MA, Reyes J, Weiss LM, Serhan CN, Tanowitz HB.

Infect Immun. 2018 Mar 22;86(4). pii: e00688-17. doi: 10.1128/IAI.00688-17. Print 2018 Apr.


Endothelin-1 Treatment Induces an Experimental Cerebral Malaria-Like Syndrome in C57BL/6 Mice Infected with Plasmodium berghei NK65.

Martins YC, Freeman BD, Akide Ndunge OB, Weiss LM, Tanowitz HB, Desruisseaux MS.

Am J Pathol. 2016 Nov;186(11):2957-2969. doi: 10.1016/j.ajpath.2016.07.020. Epub 2016 Sep 15.


Endothelin-1 Mediates Brain Microvascular Dysfunction Leading to Long-Term Cognitive Impairment in a Model of Experimental Cerebral Malaria.

Freeman BD, Martins YC, Akide-Ndunge OB, Bruno FP, Wang H, Tanowitz HB, Spray DC, Desruisseaux MS.

PLoS Pathog. 2016 Mar 31;12(3):e1005477. doi: 10.1371/journal.ppat.1005477. eCollection 2016 Mar.


Endothelin-1 and its role in the pathogenesis of infectious diseases.

Freeman BD, Machado FS, Tanowitz HB, Desruisseaux MS.

Life Sci. 2014 Nov 24;118(2):110-9. doi: 10.1016/j.lfs.2014.04.021. Epub 2014 Apr 26. Review.


Alterations in glucose homeostasis in a murine model of Chagas disease.

Nagajyothi F, Kuliawat R, Kusminski CM, Machado FS, Desruisseaux MS, Zhao D, Schwartz GJ, Huang H, Albanese C, Lisanti MP, Singh R, Li F, Weiss LM, Factor SM, Pessin JE, Scherer PE, Tanowitz HB.

Am J Pathol. 2013 Mar;182(3):886-94. doi: 10.1016/j.ajpath.2012.11.027. Epub 2013 Jan 12.


Imaging of small-animal models of infectious diseases.

Jelicks LA, Lisanti MP, Machado FS, Weiss LM, Tanowitz HB, Desruisseaux MS.

Am J Pathol. 2013 Feb;182(2):296-304. doi: 10.1016/j.ajpath.2012.09.026. Epub 2012 Nov 28. Review.


Altered regulation of Akt signaling with murine cerebral malaria, effects on long-term neuro-cognitive function, restoration with lithium treatment.

Dai M, Freeman B, Shikani HJ, Bruno FP, Collado JE, Macias R, Reznik SE, Davies P, Spray DC, Tanowitz HB, Weiss LM, Desruisseaux MS.

PLoS One. 2012;7(10):e44117. doi: 10.1371/journal.pone.0044117. Epub 2012 Oct 17.


Cerebral malaria: we have come a long way.

Shikani HJ, Freeman BD, Lisanti MP, Weiss LM, Tanowitz HB, Desruisseaux MS.

Am J Pathol. 2012 Nov;181(5):1484-92. doi: 10.1016/j.ajpath.2012.08.010. Epub 2012 Sep 25. Review.


The novel ETA receptor antagonist HJP-272 prevents cerebral microvascular hemorrhage in cerebral malaria and synergistically improves survival in combination with an artemisinin derivative.

Dai M, Freeman B, Bruno FP, Shikani HJ, Tanowitz HB, Weiss LM, Reznik SE, Stephani RA, Desruisseaux MS.

Life Sci. 2012 Oct 15;91(13-14):687-92. doi: 10.1016/j.lfs.2012.07.006. Epub 2012 Jul 17.


Response of adipose tissue to early infection with Trypanosoma cruzi (Brazil strain).

Nagajyothi F, Desruisseaux MS, Machado FS, Upadhya R, Zhao D, Schwartz GJ, Teixeira MM, Albanese C, Lisanti MP, Chua SC Jr, Weiss LM, Scherer PE, Tanowitz HB.

J Infect Dis. 2012 Mar 1;205(5):830-40. doi: 10.1093/infdis/jir840. Epub 2012 Jan 31.


Adipose tissue, diabetes and Chagas disease.

Tanowitz HB, Jelicks LA, Machado FS, Esper L, Qi X, Desruisseaux MS, Chua SC, Scherer PE, Nagajyothi F.

Adv Parasitol. 2011;76:235-50. doi: 10.1016/B978-0-12-385895-5.00010-4. Review.


Trypanosoma cruzi utilizes the host low density lipoprotein receptor in invasion.

Nagajyothi F, Weiss LM, Silver DL, Desruisseaux MS, Scherer PE, Herz J, Tanowitz HB.

PLoS Negl Trop Dis. 2011 Feb 1;5(2):e953. doi: 10.1371/journal.pntd.0000953.


Alterations in the Brain Transcriptome in Plasmodium Berghei ANKA Infected Mice.

Desruisseaux MS, Iacobas DA, Iacobas S, Mukherjee S, Weiss LM, Tanowitz HB, Spray DC.

J Neuroparasitology. 2010 Oct;1. pii: N100803.


Persistent cognitive and motor deficits after successful antimalarial treatment in murine cerebral malaria.

Dai M, Reznik SE, Spray DC, Weiss LM, Tanowitz HB, Gulinello M, Desruisseaux MS.

Microbes Infect. 2010 Dec;12(14-15):1198-207. doi: 10.1016/j.micinf.2010.08.006. Epub 2010 Aug 26.


Crucial role of the central leptin receptor in murine Trypanosoma cruzi (Brazil strain) infection.

Nagajyothi F, Zhao D, Machado FS, Weiss LM, Schwartz GJ, Desruisseaux MS, Zhao Y, Factor SM, Huang H, Albanese C, Teixeira MM, Scherer PE, Chua SC Jr, Tanowitz HB.

J Infect Dis. 2010 Oct 1;202(7):1104-13. doi: 10.1086/656189.


Cerebral malaria: a vasculopathy.

Desruisseaux MS, Machado FS, Weiss LM, Tanowitz HB, Golightly LM.

Am J Pathol. 2010 Mar;176(3):1075-8. doi: 10.2353/ajpath.2010.091090. Epub 2010 Jan 21. No abstract available.


Chagas disease, adipose tissue and the metabolic syndrome.

Nagajyothi F, Desruisseaux MS, Weiss LM, Chua S, Albanese C, Machado FS, Esper L, Lisanti MP, Teixeira MM, Scherer PE, Tanowitz HB.

Mem Inst Oswaldo Cruz. 2009 Jul;104 Suppl 1:219-25.


Perspectives on adipose tissue, chagas disease and implications for the metabolic syndrome.

Nagajyothi F, Desruisseaux MS, Jelicks LA, Machado FS, Chua S, Scherer PE, Tanowitz HB.

Interdiscip Perspect Infect Dis. 2009;2009:824324. doi: 10.1155/2009/824324. Epub 2009 Jul 26.


Trypanosoma cruzi infection of cultured adipocytes results in an inflammatory phenotype.

Nagajyothi F, Desruisseaux MS, Thiruvur N, Weiss LM, Braunstein VL, Albanese C, Teixeira MM, de Almeida CJ, Lisanti MP, Scherer PE, Tanowitz HB.

Obesity (Silver Spring). 2008 Sep;16(9):1992-7.


Cognitive dysfunction in mice infected with Plasmodium berghei strain ANKA.

Desruisseaux MS, Gulinello M, Smith DN, Lee SC, Tsuji M, Weiss LM, Spray DC, Tanowitz HB.

J Infect Dis. 2008 Jun 1;197(11):1621-7. doi: 10.1086/587908.


Thromboxane A2 is a key regulator of pathogenesis during Trypanosoma cruzi infection.

Ashton AW, Mukherjee S, Nagajyothi FN, Huang H, Braunstein VL, Desruisseaux MS, Factor SM, Lopez L, Berman JW, Wittner M, Scherer PE, Capra V, Coffman TM, Serhan CN, Gotlinger K, Wu KK, Weiss LM, Tanowitz HB.

J Exp Med. 2007 Apr 16;204(4):929-40. Epub 2007 Apr 9.


Adipocyte, adipose tissue, and infectious disease.

Desruisseaux MS, Nagajyothi, Trujillo ME, Tanowitz HB, Scherer PE.

Infect Immun. 2007 Mar;75(3):1066-78. Epub 2006 Nov 21. Review. No abstract available.


Cell cycle regulatory proteins in the liver in murine Trypanosoma cruzi infection.

Bouzahzah B, Nagajyothi F, Desruisseaux MS, Krishnamachary M, Factor SM, Cohen AW, Lisanti MP, Petkova SB, Pestell RG, Wittner M, Mukherjee S, Weiss LM, Jelicks LA, Albanese C, Tanowitz HB.

Cell Cycle. 2006 Oct;5(20):2396-400. Epub 2006 Oct 16.


Endothelin in a murine model of cerebral malaria.

Machado FS, Desruisseaux MS, Nagajyothi, Kennan RP, Hetherington HP, Wittner M, Weiss LM, Lee SC, Scherer PE, Tsuji M, Tanowitz HB.

Exp Biol Med (Maywood). 2006 Jun;231(6):1176-81.


Trypanosoma cruzi infection induces proliferation of vascular smooth muscle cells.

Hassan GS, Mukherjee S, Nagajyothi F, Weiss LM, Petkova SB, de Almeida CJ, Huang H, Desruisseaux MS, Bouzahzah B, Pestell RG, Albanese C, Christ GJ, Lisanti MP, Tanowitz HB.

Infect Immun. 2006 Jan;74(1):152-9.


Reduced cerebral blood flow and N-acetyl aspartate in a murine model of cerebral malaria.

Kennan RP, Machado FS, Lee SC, Desruisseaux MS, Wittner M, Tsuji M, Tanowitz HB.

Parasitol Res. 2005 Jul;96(5):302-7. Epub 2005 May 26.


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