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Items: 1 to 50 of 108

1.

PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer.

de Semir D, Bezrookove V, Nosrati M, Dar AA, Wu C, Shen J, Rieken C, Venkatasubramanian M, Miller JR 3rd, Desprez PY, McAllister S, Soroceanu L, Debs RJ, Salomonis N, Schadendorf D, Cleaver JE, Kashani-Sabet M.

Proc Natl Acad Sci U S A. 2018 Jun 19;115(25):E5766-E5775. doi: 10.1073/pnas.1804779115. Epub 2018 Jun 4.

PMID:
29866840
2.

Small-molecule MDM2 antagonists attenuate the senescence-associated secretory phenotype.

Wiley CD, Schaum N, Alimirah F, Lopez-Dominguez JA, Orjalo AV, Scott G, Desprez PY, Benz C, Davalos AR, Campisi J.

Sci Rep. 2018 Feb 5;8(1):2410. doi: 10.1038/s41598-018-20000-4.

3.

ZIKA vasculitis: A new cause of stroke in children?

Landais A, Césaire A, Fernandez M, Breurec S, Herrmann C, Delion F, Desprez P.

J Neurol Sci. 2017 Dec 15;383:211-213. doi: 10.1016/j.jns.2017.10.045. Epub 2017 Oct 27.

PMID:
29122294
4.

Peculiar Clinical Presentation of Coxsackievirus B4 Infection: Neonatal Restrictive Cardiomyopathy.

Le Van Quyen P, Desprez P, Livolsi A, Lindner V, Fafi-Kremer S, Helms P, Antal MC.

AJP Rep. 2017 Apr;7(2):e124-e126. doi: 10.1055/s-0037-1601352. Epub 2017 Jun 29.

5.

Apigenin suppresses the senescence-associated secretory phenotype and paracrine effects on breast cancer cells.

Perrott KM, Wiley CD, Desprez PY, Campisi J.

Geroscience. 2017 Apr;39(2):161-173. doi: 10.1007/s11357-017-9970-1. Epub 2017 Apr 4.

6.

Targeting ID2 expression triggers a more differentiated phenotype and reduces aggressiveness in human salivary gland cancer cells.

Sumida T, Ishikawa A, Nakano H, Yamada T, Mori Y, Desprez PY.

Genes Cells. 2016 Aug;21(8):915-20. doi: 10.1111/gtc.12389. Epub 2016 Jul 1. Erratum in: Genes Cells. 2016 Sep;21(9):1024.

7.

Context-dependent effects of cellular senescence in cancer development.

Lecot P, Alimirah F, Desprez PY, Campisi J, Wiley C.

Br J Cancer. 2016 May 24;114(11):1180-4. doi: 10.1038/bjc.2016.115. Epub 2016 May 3. Review.

8.

Suppression of invasion and metastasis in aggressive salivary cancer cells through targeted inhibition of ID1 gene expression.

Murase R, Sumida T, Kawamura R, Onishi-Ishikawa A, Hamakawa H, McAllister SD, Desprez PY.

Cancer Lett. 2016 Jul 10;377(1):11-6. doi: 10.1016/j.canlet.2016.04.021. Epub 2016 Apr 14.

9.

Simvastatin suppresses breast cancer cell proliferation induced by senescent cells.

Liu S, Uppal H, Demaria M, Desprez PY, Campisi J, Kapahi P.

Sci Rep. 2015 Dec 14;5:17895. doi: 10.1038/srep17895.

10.

MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation.

Laberge RM, Sun Y, Orjalo AV, Patil CK, Freund A, Zhou L, Curran SC, Davalos AR, Wilson-Edell KA, Liu S, Limbad C, Demaria M, Li P, Hubbard GB, Ikeno Y, Javors M, Desprez PY, Benz CC, Kapahi P, Nelson PS, Campisi J.

Nat Cell Biol. 2015 Aug;17(8):1049-61. doi: 10.1038/ncb3195. Epub 2015 Jul 6.

11.

The Antitumor Activity of Plant-Derived Non-Psychoactive Cannabinoids.

McAllister SD, Soroceanu L, Desprez PY.

J Neuroimmune Pharmacol. 2015 Jun;10(2):255-67. doi: 10.1007/s11481-015-9608-y. Epub 2015 Apr 28. Review.

12.

Cell Autonomous and Non-Autonomous Effects of Senescent Cells in the Skin.

Demaria M, Desprez PY, Campisi J, Velarde MC.

J Invest Dermatol. 2015 Jul;135(7):1722-1726. doi: 10.1038/jid.2015.108. Epub 2015 Apr 9. Review.

13.

[Chlamydia infection: An uncommon cause of sexually transmitted myopericarditis].

Mouquet F, Jourdain M, Desprez P, Auffray JL, Ennezat PV.

Rev Med Interne. 2015 Nov;36(11):777-9. doi: 10.1016/j.revmed.2014.12.002. Epub 2015 Jan 28. French.

PMID:
25637946
14.

Targeting multiple cannabinoid anti-tumour pathways with a resorcinol derivative leads to inhibition of advanced stages of breast cancer.

Murase R, Kawamura R, Singer E, Pakdel A, Sarma P, Judkins J, Elwakeel E, Dayal S, Martinez-Martinez E, Amere M, Gujjar R, Mahadevan A, Desprez PY, McAllister SD.

Br J Pharmacol. 2014 Oct;171(19):4464-77. doi: 10.1111/bph.12803. Epub 2014 Sep 5.

15.

Invasive pneumococcal disease in children can reveal a primary immunodeficiency.

Gaschignard J, Levy C, Chrabieh M, Boisson B, Bost-Bru C, Dauger S, Dubos F, Durand P, Gaudelus J, Gendrel D, Gras Le Guen C, Grimprel E, Guyon G, Jeudy C, Jeziorski E, Leclerc F, Léger PL, Lesage F, Lorrot M, Pellier I, Pinquier D, de Pontual L, Sachs P, Thomas C, Tissières P, Valla FV, Desprez P, Frémeaux-Bacchi V, Varon E, Bossuyt X, Cohen R, Abel L, Casanova JL, Puel A, Picard C.

Clin Infect Dis. 2014 Jul 15;59(2):244-51. doi: 10.1093/cid/ciu274. Epub 2014 Apr 23.

16.

Next-generation sequencing (NGS) as a fast molecular diagnosis tool for left ventricular noncompaction in an infant with compound mutations in the MYBPC3 gene.

Schaefer E, Helms P, Marcellin L, Desprez P, Billaud P, Chanavat V, Rousson R, Millat G.

Eur J Med Genet. 2014 Mar;57(4):129-32. doi: 10.1016/j.ejmg.2014.02.015. Epub 2014 Mar 4.

PMID:
24602869
17.

Mitochondrial DNA damage induces apoptosis in senescent cells.

Laberge RM, Adler D, DeMaria M, Mechtouf N, Teachenor R, Cardin GB, Desprez PY, Campisi J, Rodier F.

Cell Death Dis. 2013 Jul 18;4:e727. doi: 10.1038/cddis.2013.199.

18.

Targeting Id1 reduces proliferation and invasion in aggressive human salivary gland cancer cells.

Sumida T, Murase R, Onishi-Ishikawa A, McAllister SD, Hamakawa H, Desprez PY.

BMC Cancer. 2013 Mar 22;13:141. doi: 10.1186/1471-2407-13-141.

19.

Supraclavicular ultrasound-guided catheterization of the subclavian vein in pediatric and neonatal ICUs: a feasibility study.

Guilbert AS, Xavier L, Ammouche C, Desprez P, Astruc D, Diemunsch P, Bientz J.

Pediatr Crit Care Med. 2013 May;14(4):351-5. doi: 10.1097/PCC.0b013e3182745489.

PMID:
23392376
20.

Id-1 is a key transcriptional regulator of glioblastoma aggressiveness and a novel therapeutic target.

Soroceanu L, Murase R, Limbad C, Singer E, Allison J, Adrados I, Kawamura R, Pakdel A, Fukuyo Y, Nguyen D, Khan S, Arauz R, Yount GL, Moore DH, Desprez PY, McAllister SD.

Cancer Res. 2013 Mar 1;73(5):1559-69. doi: 10.1158/0008-5472.CAN-12-1943. Epub 2012 Dec 13.

21.

Responses of human embryonic stem cells and their differentiated progeny to ionizing radiation.

Zou Y, Zhang N, Ellerby LM, Davalos AR, Zeng X, Campisi J, Desprez PY.

Biochem Biophys Res Commun. 2012 Sep 14;426(1):100-5. doi: 10.1016/j.bbrc.2012.08.043. Epub 2012 Aug 14.

22.

Glucocorticoids suppress selected components of the senescence-associated secretory phenotype.

Laberge RM, Zhou L, Sarantos MR, Rodier F, Freund A, de Keizer PL, Liu S, Demaria M, Cong YS, Kapahi P, Desprez PY, Hughes RE, Campisi J.

Aging Cell. 2012 Aug;11(4):569-78. doi: 10.1111/j.1474-9726.2012.00818.x. Epub 2012 Apr 17.

23.

Concomitant chemoradiotherapy versus acceleration of radiotherapy with or without concomitant chemotherapy in locally advanced head and neck carcinoma (GORTEC 99-02): an open-label phase 3 randomised trial.

Bourhis J, Sire C, Graff P, Grégoire V, Maingon P, Calais G, Gery B, Martin L, Alfonsi M, Desprez P, Pignon T, Bardet E, Rives M, Geoffrois L, Daly-Schveitzer N, Sen S, Tuchais C, Dupuis O, Guerif S, Lapeyre M, Favrel V, Hamoir M, Lusinchi A, Temam S, Pinna A, Tao YG, Blanchard P, Aupérin A.

Lancet Oncol. 2012 Feb;13(2):145-53. doi: 10.1016/S1470-2045(11)70346-1. Epub 2012 Jan 18.

PMID:
22261362
24.

Novel therapeutic strategies for malignant salivary gland tumors: lessons learned from breast cancer.

Murase R, Sumida T, Ishikawa A, Murase R, McAllister SD, Hamakawa H, Desprez PY.

Int J Otolaryngol. 2011;2011:187623. doi: 10.1155/2011/187623. Epub 2011 Nov 21.

25.

Tumor suppressor and aging biomarker p16(INK4a) induces cellular senescence without the associated inflammatory secretory phenotype.

Coppé JP, Rodier F, Patil CK, Freund A, Desprez PY, Campisi J.

J Biol Chem. 2011 Oct 21;286(42):36396-403. doi: 10.1074/jbc.M111.257071. Epub 2011 Aug 31.

26.

Epithelial-mesenchymal transition induced by senescent fibroblasts.

Laberge RM, Awad P, Campisi J, Desprez PY.

Cancer Microenviron. 2012 Apr;5(1):39-44. doi: 10.1007/s12307-011-0069-4. Epub 2011 Jun 25.

27.

[Anti-PF4 antibodies and thrombophlebitis in a child with cerebral venous thrombosis].

Desprez D, Desprez P, Tardy B, Amiral J, Droulle C, Ducassou S, Mauvieux L, Grunebaum L.

Ann Biol Clin (Paris). 2010 Nov-Dec;68(6):725-8. doi: 10.1684/abc.2010.0474. French.

28.

Vascular endothelial platelet endothelial cell adhesion molecule 1 (PECAM-1) regulates advanced metastatic progression.

DeLisser H, Liu Y, Desprez PY, Thor A, Briasouli P, Handumrongkul C, Wilfong J, Yount G, Nosrati M, Fong S, Shtivelman E, Fehrenbach M, Cao G, Moore DH, Nayak S, Liggitt D, Kashani-Sabet M, Debs R.

Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18616-21. doi: 10.1073/pnas.1004654107. Epub 2010 Oct 6. Erratum in: Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3821. Nyack, Shruti [corrected to Nayak, Shruti].

29.

Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis.

McAllister SD, Murase R, Christian RT, Lau D, Zielinski AJ, Allison J, Almanza C, Pakdel A, Lee J, Limbad C, Liu Y, Debs RJ, Moore DH, Desprez PY.

Breast Cancer Res Treat. 2011 Aug;129(1):37-47. doi: 10.1007/s10549-010-1177-4. Epub 2010 Sep 22. Erratum in: Breast Cancer Res Treat. 2012 May;133(1):401-4.

30.

Osteosclerotic bone dysplasia in siblings with a Fam20C mutation.

Fradin M, Stoetzel C, Muller J, Koob M, Christmann D, Debry C, Kohler M, Isnard M, Astruc D, Desprez P, Zorres C, Flori E, Dollfus H, Doray B.

Clin Genet. 2011 Aug;80(2):177-83. doi: 10.1111/j.1399-0004.2010.01516.x. Epub 2010 Jul 23.

PMID:
20825432
31.

Inflammatory networks during cellular senescence: causes and consequences.

Freund A, Orjalo AV, Desprez PY, Campisi J.

Trends Mol Med. 2010 May;16(5):238-46. doi: 10.1016/j.molmed.2010.03.003. Epub 2010 May 3. Review.

32.

Senescent cells as a source of inflammatory factors for tumor progression.

Davalos AR, Coppe JP, Campisi J, Desprez PY.

Cancer Metastasis Rev. 2010 Jun;29(2):273-83. doi: 10.1007/s10555-010-9220-9. Review.

33.

[Non IgE-dependent milk protein and extensifs hydrolysats hypersensitivity revealed by atopic dermatitis, hypotrophy and polyuria].

Aboudiab T, Bourghol J, Boulot F, Al Hawari S, Léké L, Desprez P.

Arch Pediatr. 2010 Apr;17(4):429-30. doi: 10.1016/j.arcped.2010.01.019. Epub 2010 Feb 26. French. No abstract available.

PMID:
20189362
34.

A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen.

Coppé JP, Patil CK, Rodier F, Krtolica A, Beauséjour CM, Parrinello S, Hodgson JG, Chin K, Desprez PY, Campisi J.

PLoS One. 2010 Feb 12;5(2):e9188. doi: 10.1371/journal.pone.0009188.

35.

The senescence-associated secretory phenotype: the dark side of tumor suppression.

Coppé JP, Desprez PY, Krtolica A, Campisi J.

Annu Rev Pathol. 2010;5:99-118. doi: 10.1146/annurev-pathol-121808-102144. Review.

36.

Cannabidiol enhances the inhibitory effects of delta9-tetrahydrocannabinol on human glioblastoma cell proliferation and survival.

Marcu JP, Christian RT, Lau D, Zielinski AJ, Horowitz MP, Lee J, Pakdel A, Allison J, Limbad C, Moore DH, Yount GL, Desprez PY, McAllister SD.

Mol Cancer Ther. 2010 Jan;9(1):180-9. doi: 10.1158/1535-7163.MCT-09-0407. Epub 2010 Jan 6.

37.

The helix-loop-helix Id-1 inhibits PSA expression in prostate cancer cells.

Zielinski AJ, Fong S, Allison J, Kawahara M, Coppe JP, Feiler H, Lee NM, Desprez PY.

Int J Cancer. 2010 May 15;126(10):2490-6. doi: 10.1002/ijc.24811.

38.

[Non invasive ventilation for acute respiratory distress with febrile aplastic anemia].

Desprez P, Ribstein AL, Didier C, Barats A, Scheib C, Defaix A, Lutz P, Astruc D.

Arch Pediatr. 2009 Jun;16(6):750-1. doi: 10.1016/S0929-693X(09)74137-5. French. No abstract available.

PMID:
19541155
39.

[Non invasive ventilation in children with acute respiratory failure during RSV epidemic period: a prospective multicenter study].

Javouhey E, Massenavette B, Binoche A, Desprez P, Ramadan-Ghostine G, Guillermet C, Floret D, Leclerc F.

Arch Pediatr. 2009 Jun;16(6):729-31. doi: 10.1016/S0929-693X(09)74129-6. French. No abstract available.

PMID:
19541147
40.

A novel form of the telomere-associated protein TIN2 localizes to the nuclear matrix.

Kaminker PG, Kim SH, Desprez PY, Campisi J.

Cell Cycle. 2009 Mar 15;8(6):931-9. Epub 2009 Mar 26.

41.

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor.

Coppé JP, Patil CK, Rodier F, Sun Y, Muñoz DP, Goldstein J, Nelson PS, Desprez PY, Campisi J.

PLoS Biol. 2008 Dec 2;6(12):2853-68. doi: 10.1371/journal.pbio.0060301.

42.

Use of digital camera imaging of eye fundus for telemedicine in children suspected of abusive head injury.

Saleh M, Schoenlaub S, Desprez P, Bourcier T, Gaucher D, Astruc D, Speeg-Schatz C.

Br J Ophthalmol. 2009 Apr;93(4):424-8. doi: 10.1136/bjo.2008.147561. Epub 2008 Nov 19.

PMID:
19019943
43.

A role for fibroblasts in mediating the effects of tobacco-induced epithelial cell growth and invasion.

Coppe JP, Boysen M, Sun CH, Wong BJ, Kang MK, Park NH, Desprez PY, Campisi J, Krtolica A.

Mol Cancer Res. 2008 Jul;6(7):1085-98. doi: 10.1158/1541-7786.MCR-08-0062.

44.

Expression of Id and ITF-2 genes in the mammary gland during pregnancy.

Itahana Y, Piens M, Fong S, Singh J, Sumida T, Desprez PY.

Biochem Biophys Res Commun. 2008 Aug 8;372(4):826-30. doi: 10.1016/j.bbrc.2008.05.139. Epub 2008 Jun 2.

45.

Regulation of Id1 expression by SRC: implications for targeting of the bone morphogenetic protein pathway in cancer.

Gautschi O, Tepper CG, Purnell PR, Izumiya Y, Evans CP, Green TP, Desprez PY, Lara PN, Gandara DR, Mack PC, Kung HJ.

Cancer Res. 2008 Apr 1;68(7):2250-8. doi: 10.1158/0008-5472.CAN-07-6403.

46.

Growth inhibition of human salivary gland tumor cells by introduction of progesterone (Pg) receptor and Pg treatment.

Yoshimura T, Sumida T, Liu S, Onishi A, Shintani S, Desprez PY, Hamakawa H.

Endocr Relat Cancer. 2007 Dec;14(4):1107-16.

PMID:
18045962
47.

Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells.

McAllister SD, Christian RT, Horowitz MP, Garcia A, Desprez PY.

Mol Cancer Ther. 2007 Nov;6(11):2921-7.

48.

Transforming growth factor-beta can suppress tumorigenesis through effects on the putative cancer stem or early progenitor cell and committed progeny in a breast cancer xenograft model.

Tang B, Yoo N, Vu M, Mamura M, Nam JS, Ooshima A, Du Z, Desprez PY, Anver MR, Michalowska AM, Shih J, Parks WT, Wakefield LM.

Cancer Res. 2007 Sep 15;67(18):8643-52.

49.

E6/E7 of HPV type 16 promotes cell invasion and metastasis of human breast cancer cells.

Yasmeen A, Bismar TA, Kandouz M, Foulkes WD, Desprez PY, Al Moustafa AE.

Cell Cycle. 2007 Aug 15;6(16):2038-42. Epub 2007 Jun 6.

PMID:
17721085
50.

Regulation of clusterin expression in mammary epithelial cells.

Itahana Y, Piens M, Sumida T, Fong S, Muschler J, Desprez PY.

Exp Cell Res. 2007 Mar 10;313(5):943-51. Epub 2006 Dec 24.

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