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Items: 26


Lupus Autoimmunity and Metabolic Parameters Are Exacerbated Upon High Fat Diet-Induced Obesity Due to TLR7 Signaling.

Hanna Kazazian N, Wang Y, Roussel-Queval A, Marcadet L, Chasson L, Laprie C, Desnues B, Charaix J, Irla M, Alexopoulou L.

Front Immunol. 2019 Sep 4;10:2015. doi: 10.3389/fimmu.2019.02015. eCollection 2019.


Tumor Necrosis Factor-Alpha Antagonist Interferes With the Formation of Granulomatous Multinucleated Giant Cells: New Insights Into Mycobacterium tuberculosis Infection.

Mezouar S, Diarra I, Roudier J, Desnues B, Mege JL.

Front Immunol. 2019 Aug 14;10:1947. doi: 10.3389/fimmu.2019.01947. eCollection 2019.


Mast Cell Cytonemes as a Defense Mechanism against Coxiella burnetii.

Mezouar S, Vitte J, Gorvel L, Ben Amara A, Desnues B, Mege JL.

MBio. 2019 Apr 16;10(2). pii: e02669-18. doi: 10.1128/mBio.02669-18.


Tropheryma whipplei Increases Expression of Human Leukocyte Antigen-G on Monocytes to Reduce Tumor Necrosis Factor and Promote Bacterial Replication.

Ben Azzouz E, Boumaza A, Mezouar S, Bardou M, Carlini F, Picard C, Raoult D, Mège JL, Desnues B.

Gastroenterology. 2018 Nov;155(5):1553-1563. doi: 10.1053/j.gastro.2018.07.034. Epub 2018 Aug 1.


The transcriptional repressor Gfi1 prevents lupus autoimmunity by restraining TLR7 signaling.

Desnues B, Macedo AB, Ordoñez-Rueda D, Roussel-Queval A, Malissen B, Bruhns P, Malissen M, Alexopoulou L.

Eur J Immunol. 2016 Dec;46(12):2801-2811. doi: 10.1002/eji.201646573. Epub 2016 Oct 4.


TLR8 on dendritic cells and TLR9 on B cells restrain TLR7-mediated spontaneous autoimmunity in C57BL/6 mice.

Desnues B, Macedo AB, Roussel-Queval A, Bonnardel J, Henri S, Demaria O, Alexopoulou L.

Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1497-502. doi: 10.1073/pnas.1314121111. Epub 2014 Jan 13.


Sex bias in susceptibility to MCMV infection: implication of TLR9.

Traub S, Demaria O, Chasson L, Serra F, Desnues B, Alexopoulou L.

PLoS One. 2012;7(9):e45171. doi: 10.1371/journal.pone.0045171. Epub 2012 Sep 20.


[Toll-like receptor 8: the awkward TLR].

Alexopoulou L, Desnues B, Demaria O.

Med Sci (Paris). 2012 Jan;28(1):96-102. doi: 10.1051/medsci/2012281023. Epub 2012 Jan 27. French.


An experimental mouse model to establish Tropheryma whipplei as a diarrheal agent.

Al Moussawi K, Malou N, Mege JL, Raoult D, Desnues B.

J Infect Dis. 2011 Jul 1;204(1):44-50. doi: 10.1093/infdis/jir219.


Tropheryma whipplei, the Whipple's disease bacillus, induces macrophage apoptosis through the extrinsic pathway.

Gorvel L, Al Moussawi K, Ghigo E, Capo C, Mege JL, Desnues B.

Cell Death Dis. 2010 Apr 8;1:e34. doi: 10.1038/cddis.2010.11.


Defining causality in emerging agents of acute bacterial diarrheas: a step beyond the Koch's postulates.

Desnues B, Al Moussawi K, Raoult D.

Future Microbiol. 2010 Dec;5(12):1787-97. doi: 10.2217/fmb.10.141. Review.


IL-16 promotes T. whipplei replication by inhibiting phagosome conversion and modulating macrophage activation.

Ghigo E, Barry AO, Pretat L, Al Moussawi K, Desnues B, Capo C, Kornfeld H, Mege JL.

PLoS One. 2010 Oct 21;5(10):e13561. doi: 10.1371/journal.pone.0013561.


New insights into Whipple's disease and Tropheryma whipplei infections.

Desnues B, Al Moussawi K, Fenollar F.

Microbes Infect. 2010 Dec;12(14-15):1102-10. doi: 10.1016/j.micinf.2010.08.001. Epub 2010 Aug 11. Review.


Type I interferon induction is detrimental during infection with the Whipple's disease bacterium, Tropheryma whipplei.

Al Moussawi K, Ghigo E, Kalinke U, Alexopoulou L, Mege JL, Desnues B.

PLoS Pathog. 2010 Jan 15;6(1):e1000722. doi: 10.1371/journal.ppat.1000722.


Role of the cytoplasmic pattern recognition receptor Nod2 in Coxiella burnetii infection.

Benoit M, Bechah Y, Capo C, Murray PJ, Mege JL, Desnues B.

Clin Microbiol Infect. 2009 Dec;15 Suppl 2:154-5. doi: 10.1111/j.1469-0691.2008.02270.x. Epub 2009 Jun 22. No abstract available.


Intracellular life of Coxiella burnetii in macrophages.

Ghigo E, Pretat L, Desnues B, Capo C, Raoult D, Mege JL.

Ann N Y Acad Sci. 2009 May;1166:55-66. doi: 10.1111/j.1749-6632.2009.04515.x. Review.


Role of specific antibodies in Coxiella burnetii infection of macrophages.

Desnues B, Imbert G, Raoult D, Mege JL, Ghigo E.

Clin Microbiol Infect. 2009 Dec;15 Suppl 2:161-2. doi: 10.1111/j.1469-0691.2008.02208.x. Epub 2009 Mar 11. No abstract available.


Tropheryma whipplei glycosylation in the pathophysiologic profile of Whipple's disease.

Bonhomme CJ, Renesto P, Desnues B, Ghigo E, Lepidi H, Fourquet P, Fenollar F, Henrissat B, Mege JL, Raoult D.

J Infect Dis. 2009 Apr 1;199(7):1043-52. doi: 10.1086/597277.


Macrophage polarization in bacterial infections.

Benoit M, Desnues B, Mege JL.

J Immunol. 2008 Sep 15;181(6):3733-9. Review.


CNF1-induced ubiquitylation and proteasome destruction of activated RhoA is impaired in Smurf1-/- cells.

Boyer L, Turchi L, Desnues B, Doye A, Ponzio G, Mege JL, Yamashita M, Zhang YE, Bertoglio J, Flatau G, Boquet P, Lemichez E.

Mol Biol Cell. 2006 Jun;17(6):2489-97. Epub 2006 Mar 15.


Whipple's disease: a macrophage disease.

Desnues B, Ihrig M, Raoult D, Mege JL.

Clin Vaccine Immunol. 2006 Feb;13(2):170-8. Review. No abstract available.


Whipple disease: intestinal infiltrating cells exhibit a transcriptional pattern of M2/alternatively activated macrophages.

Desnues B, Lepidi H, Raoult D, Mege JL.

J Infect Dis. 2005 Nov 1;192(9):1642-6. Epub 2005 Sep 30.


IL-16 is critical for Tropheryma whipplei replication in Whipple's disease.

Desnues B, Raoult D, Mege JL.

J Immunol. 2005 Oct 1;175(7):4575-82.


Lack of microbicidal response in human macrophages infected with Parachlamydia acanthamoebae.

Greub G, Desnues B, Raoult D, Mege JL.

Microbes Infect. 2005 Apr;7(4):714-9. Epub 2005 Mar 21.


Differential oxidative damage and expression of stress defence regulons in culturable and non-culturable Escherichia coli cells.

Desnues B, Cuny C, Grégori G, Dukan S, Aguilaniu H, Nyström T.

EMBO Rep. 2003 Apr;4(4):400-4.

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