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Items: 1 to 50 of 184

1.

Perioperative intravenous low-dose ketamine for neuropathic pain after major lower back surgery: A randomized, placebo-controlled study.

Czarnetzki C, Desmeules J, Tessitore E, Faundez A, Chabert J, Daali Y, Fournier R, Dupuis-Lozeron E, Cedraschi C, Richard Tramèr M.

Eur J Pain. 2019 Nov 19. doi: 10.1002/ejp.1507. [Epub ahead of print]

PMID:
31743533
2.

Snapshot of proton pump inhibitors prescriptions in a tertiary care hospital in Switzerland: less is more?

Lenoir C, El Biali M, Luthy C, Grosgurin O, Desmeules JA, Rollason V.

Int J Clin Pharm. 2019 Dec;41(6):1634-1641. doi: 10.1007/s11096-019-00929-w. Epub 2019 Oct 29.

PMID:
31664687
3.

Cytochrome P450 1A2 activity and incidence of thyroid disease and cancer after chronic or acute exposure to dioxins.

Samer CF, Gloor Y, Rollason V, Guessous I, Doffey-Lazeyras F, Saurat JH, Sorg O, Desmeules J, Daali Y.

Basic Clin Pharmacol Toxicol. 2019 Oct 14. doi: 10.1111/bcpt.13339. [Epub ahead of print]

PMID:
31608602
4.

Toward precision medicine in pediatric population using cytochrome P450 phenotyping approaches and physiologically based pharmacokinetic modeling.

Magliocco G, Rodieux F, Desmeules J, Samer CF, Daali Y.

Pediatr Res. 2019 Oct 10. doi: 10.1038/s41390-019-0609-z. [Epub ahead of print] Review.

PMID:
31600772
5.

Interaction between Fexofenadine and CYP Phenotyping Probe Drugs in Geneva Cocktail.

Bosilkovska M, Magliocco G, Desmeules J, Samer C, Daali Y.

J Pers Med. 2019 Oct 2;9(4). pii: E45. doi: 10.3390/jpm9040045.

6.

Comparing Dried Blood Spots and Plasma Concentrations for Busulfan Therapeutic Drug Monitoring in Children.

Dilo A, Daali Y, Desmeules J, Chalandon Y, Uppugunduri CRS, Ansari M.

Ther Drug Monit. 2020 Feb;42(1):111-117. doi: 10.1097/FTD.0000000000000673.

PMID:
31348116
7.

Development of a predictive score for potentially avoidable hospital readmissions for general internal medicine patients.

Blanc AL, Fumeaux T, Stirnemann J, Dupuis Lozeron E, Ourhamoune A, Desmeules J, Chopard P, Perrier A, Schaad N, Bonnabry P.

PLoS One. 2019 Jul 15;14(7):e0219348. doi: 10.1371/journal.pone.0219348. eCollection 2019.

8.

Physiologically-Based Pharmacokinetic Modeling for the Prediction of CYP2D6-Mediated Gene-Drug-Drug Interactions.

Storelli F, Desmeules J, Daali Y.

CPT Pharmacometrics Syst Pharmacol. 2019 Aug;8(8):567-576. doi: 10.1002/psp4.12411. Epub 2019 Jul 3.

9.

[Why propose cognitive-behavioural therapy for chronic pain patients ?]

Souche A, Piguet V, Desmeules J, Cedraschi C.

Rev Med Suisse. 2019 Jun 19;15(656):1272-1275. French.

PMID:
31268255
10.

Phenotyping of Human CYP450 Enzymes by Endobiotics: Current Knowledge and Methodological Approaches.

Magliocco G, Thomas A, Desmeules J, Daali Y.

Clin Pharmacokinet. 2019 Nov;58(11):1373-1391. doi: 10.1007/s40262-019-00783-z. Review.

PMID:
31131437
11.

A case report of cholinergic rebound syndrome following abrupt low-dose clozapine discontinuation in a patient with type I bipolar affective disorder.

Galova A, Berney P, Desmeules J, Sergentanis I, Besson M.

BMC Psychiatry. 2019 Feb 19;19(1):73. doi: 10.1186/s12888-019-2055-1.

12.

Safety Issues of Pharmacological Acute Pain Treatment in Children.

Rodieux F, Piguet V, Desmeules J, Samer CF.

Clin Pharmacol Ther. 2019 May;105(5):1130-1138. doi: 10.1002/cpt.1358. Epub 2019 Mar 1. Review.

PMID:
30648741
13.

Genotype-sensitive reversible and time-dependent CYP2D6 inhibition in human liver microsomes.

Storelli F, Desmeules J, Daali Y.

Basic Clin Pharmacol Toxicol. 2019 Feb;124(2):170-180. doi: 10.1111/bcpt.13124. Epub 2018 Oct 11.

PMID:
30192434
14.

[Acute pain management in opioid-maintained patients].

Manguzzi E, Wainstein L, Desmeules J, Broers B.

Rev Med Suisse. 2018 Jun 20;14(612):1280-1285. French.

PMID:
29944294
15.

[Opioids prescription in the vulnerable populations : the children and the elderly. Practical guidelines].

Rodieux F, Lloret-Linares C, Piguet V, Desmeules J.

Rev Med Suisse. 2018 Jun 20;14(612):1268-1278. French.

PMID:
29944293
16.

Severe and persistent morphine-induced respiratory depression associated with ATP-Binding Cassette Subfamily B Member 1 and catechol-O-methyltransferase genetic defects: A case report.

Aebischer G, Ing Lorenzini K, Tomala S, Desmeules J, Daali Y, Samer CF.

Eur J Anaesthesiol. 2018 Jul;35(7):540-542. doi: 10.1097/EJA.0000000000000801. No abstract available.

PMID:
29870475
17.

Complex Drug-Drug-Gene-Disease Interactions Involving Cytochromes P450: Systematic Review of Published Case Reports and Clinical Perspectives.

Storelli F, Samer C, Reny JL, Desmeules J, Daali Y.

Clin Pharmacokinet. 2018 Oct;57(10):1267-1293. doi: 10.1007/s40262-018-0650-9. Review.

PMID:
29667038
18.

Phenotypic Assessment of Drug Metabolic Pathways and P-Glycoprotein in Patients Treated With Antidepressants in an Ambulatory Setting.

Lloret-Linares C, Bosilkovska M, Daali Y, Gex-Fabry M, Heron K, Bancila V, Michalopoulos G, Perroud N, Richard-Lepouriel H, Aubry JM, Desmeules J, Besson M.

J Clin Psychiatry. 2018 Mar/Apr;79(2). pii: 16m11387. doi: 10.4088/JCP.16m11387.

PMID:
29570971
19.

When the Safe Alternative Is Not That Safe: Tramadol Prescribing in Children.

Rodieux F, Vutskits L, Posfay-Barbe KM, Habre W, Piguet V, Desmeules JA, Samer CF.

Front Pharmacol. 2018 Mar 5;9:148. doi: 10.3389/fphar.2018.00148. eCollection 2018. Review.

20.

Impact of Boosted Antiretroviral Therapy on the Pharmacokinetics and Efficacy of Clopidogrel and Prasugrel Active Metabolites.

Marsousi N, Daali Y, Fontana P, Reny JL, Ancrenaz-Sirot V, Calmy A, Rudaz S, Desmeules JA, Samer CF.

Clin Pharmacokinet. 2018 Oct;57(10):1347-1354. doi: 10.1007/s40262-018-0637-6.

PMID:
29453687
21.

Exploring venlafaxine pharmacokinetic variability with a phenotyping approach, a multicentric french-swiss study (MARVEL study).

Lloret-Linares C, Daali Y, Chevret S, Nieto I, Molière F, Courtet P, Galtier F, Richieri RM, Morange S, Llorca PM, El-Hage W, Desmidt T, Haesebaert F, Vignaud P, Holtzmann J, Cracowski JL, Leboyer M, Yrondi A, Calvas F, Yon L, Le Corvoisier P, Doumy O, Heron K, Montange D, Davani S, Déglon J, Besson M, Desmeules J, Haffen E, Bellivier F.

BMC Pharmacol Toxicol. 2017 Nov 7;18(1):70. doi: 10.1186/s40360-017-0173-2.

22.

Prediction of drug-drug interactions using physiologically-based pharmacokinetic models of CYP450 modulators included in Simcyp software.

Marsousi N, Desmeules JA, Rudaz S, Daali Y.

Biopharm Drug Dispos. 2018 Jan;39(1):3-17. doi: 10.1002/bdd.2107. Epub 2017 Nov 20.

PMID:
28960401
23.

Impact of CYP2D6 Functional Allelic Variations on Phenoconversion and Drug-Drug Interactions.

Storelli F, Matthey A, Lenglet S, Thomas A, Desmeules J, Daali Y.

Clin Pharmacol Ther. 2018 Jul;104(1):148-157. doi: 10.1002/cpt.889. Epub 2017 Nov 6.

PMID:
28940476
24.

PIM-Check: development of an international prescription-screening checklist designed by a Delphi method for internal medicine patients.

Desnoyer A, Blanc AL, Pourcher V, Besson M, Fonzo-Christe C, Desmeules J, Perrier A, Bonnabry P, Samer C, Guignard B.

BMJ Open. 2017 Jul 31;7(7):e016070. doi: 10.1136/bmjopen-2017-016070.

25.

"Late" Withdrawal Syndrome after Carbamazepine In Utero Exposure in a CYP2C9 Slow Metabolizer Newborn.

Passia E, Rock N, Pfister RE, Ing Lorenzini KR, Desmeules J, Samer CF.

Front Pharmacol. 2017 Apr 21;8:217. doi: 10.3389/fphar.2017.00217. eCollection 2017.

26.

Usefulness of PBPK Modeling in Incorporation of Clinical Conditions in Personalized Medicine.

Marsousi N, Desmeules JA, Rudaz S, Daali Y.

J Pharm Sci. 2017 Sep;106(9):2380-2391. doi: 10.1016/j.xphs.2017.04.035. Epub 2017 Apr 26. Review.

PMID:
28456730
27.

Rivaroxaban-Induced Hemorrhage Associated with ABCB1 Genetic Defect.

Ing Lorenzini K, Daali Y, Fontana P, Desmeules J, Samer C.

Front Pharmacol. 2016 Dec 19;7:494. doi: 10.3389/fphar.2016.00494. eCollection 2016.

28.

Hepatocyte Concentrations of Indocyanine Green Reflect Transfer Rates Across Membrane Transporters.

Cusin F, Fernandes Azevedo L, Bonnaventure P, Desmeules J, Daali Y, Pastor CM.

Basic Clin Pharmacol Toxicol. 2017 Feb;120(2):171-178. doi: 10.1111/bcpt.12671. Epub 2016 Nov 3.

29.

Characterization of oxycodone in vitro metabolism by human cytochromes P450 and UDP-glucuronosyltransferases.

Romand S, Spaggiari D, Marsousi N, Samer C, Desmeules J, Daali Y, Rudaz S.

J Pharm Biomed Anal. 2017 Sep 10;144:129-137. doi: 10.1016/j.jpba.2016.09.024. Epub 2016 Sep 26.

PMID:
27692933
30.

[Potentially inappropriate medications in geriatrics: Which tools to detect them?]

Desnoyer A, Guignard B, Lang PO, Desmeules J, Vogt-Ferrier N, Bonnabry P.

Presse Med. 2016 Nov;45(11):957-970. doi: 10.1016/j.lpm.2016.06.033. Epub 2016 Sep 12. Review. French.

PMID:
27633589
31.

[It is not only about cost ... when it comes to generic medication].

Piguet V, D'Incau S, Besson M, Desmeules J, Cedraschi C.

Rev Med Suisse. 2016 Jun 22;12(524):1230-3. French.

PMID:
27506067
32.

Snapshot of the prescribing practice for the clopidogrel and esomeprazole coprescription and cost evaluation of the application guidelines.

Vernaz N, Rollason V, Adlere L, Combescure C, Poncet A, Bonnabry P, Desmeules J.

Pharmacol Res Perspect. 2016 Apr 21;4(3):e00234. doi: 10.1002/prp2.234. eCollection 2016 Jun.

33.

Intestinal permeability and P-glycoprotein-mediated efflux transport of ticagrelor in Caco-2 monolayer cells.

Marsousi N, Doffey-Lazeyras F, Rudaz S, Desmeules JA, Daali Y.

Fundam Clin Pharmacol. 2016 Dec;30(6):577-584. doi: 10.1111/fcp.12219. Epub 2016 Aug 5.

PMID:
27416295
34.

The clobazam metabolite N-desmethyl clobazam is an α2 preferring benzodiazepine with an improved therapeutic window for antihyperalgesia.

Ralvenius WT, Acuña MA, Benke D, Matthey A, Daali Y, Rudolph U, Desmeules J, Zeilhofer HU, Besson M.

Neuropharmacology. 2016 Oct;109:366-375. doi: 10.1016/j.neuropharm.2016.07.004. Epub 2016 Jul 5.

35.

Screening for genotypic and phenotypic variations in CYP450 activity in patients with therapeutic problems in a psychiatric setting, a retrospective study.

Lloret-Linares C, Rollason V, Lorenzini KI, Samer C, Daali Y, Gex-Fabry M, Aubry JM, Desmeules J, Besson M.

Pharmacol Res. 2017 Apr;118:104-110. doi: 10.1016/j.phrs.2016.07.002. Epub 2016 Jul 1.

36.

Coadministration of ticagrelor and ritonavir: Toward prospective dose adjustment to maintain an optimal platelet inhibition using the PBPK approach.

Marsousi N, Samer CF, Fontana P, Reny JL, Rudaz S, Desmeules JA, Daali Y.

Clin Pharmacol Ther. 2016 Sep;100(3):295-304. doi: 10.1002/cpt.407. Epub 2016 Jul 25.

PMID:
27264793
37.

Evaluation of Mutual Drug-Drug Interaction within Geneva Cocktail for Cytochrome P450 Phenotyping using Innovative Dried Blood Sampling Method.

Bosilkovska M, Samer C, Déglon J, Thomas A, Walder B, Desmeules J, Daali Y.

Basic Clin Pharmacol Toxicol. 2016 Sep;119(3):284-90. doi: 10.1111/bcpt.12586. Epub 2016 Apr 25.

38.

Pharmacogenomics of Oral Antithrombotic Drugs.

Storelli F, Daali Y, Desmeules J, Reny JL, Fontana P.

Curr Pharm Des. 2016;22(13):1933-49. Review.

PMID:
26642774
39.

Severe Vincristine-induced Neuropathic Pain in a CYP3A5 Nonexpressor With Reduced CYP3A4/5 Activity: Case Study.

Bosilkovska M, Ing Lorenzini K, Uppugunduri CR, Desmeules J, Daali Y, Escher M.

Clin Ther. 2016 Jan 1;38(1):216-20. doi: 10.1016/j.clinthera.2015.10.017. Epub 2015 Nov 10.

PMID:
26565076
40.

Use of metamizole in children and the risk of agranulocytosis: Is the benefit worth the risk?

Rollason V, Desmeules JA.

Eur J Anaesthesiol. 2015 Dec;32(12):837-8. doi: 10.1097/EJA.0000000000000275. No abstract available.

PMID:
26509242
41.

Meta-xylene: identification of a new antigenic entity in hypersensitivity reactions to local anesthetics.

Ing Lorenzini K, Gay-Crosier Chabry F, Piguet C, Desmeules J.

J Allergy Clin Immunol Pract. 2016 Jan-Feb;4(1):162-4. doi: 10.1016/j.jaip.2015.08.005. Epub 2015 Oct 1. No abstract available.

PMID:
26432515
42.

Is pholcodine a dangerous cough suppressant?

Ing Lorenzini K, Desmeules J, Piguet V.

Eur J Anaesthesiol. 2015 Nov;32(11):749-50. doi: 10.1097/EJA.0000000000000306. No abstract available.

PMID:
26426574
43.

[Clinical pharmacology of medical cannabinoids in chronic pain].

Ing Lorenzini K, Broers B, Lalive PH, Dayer P, Desmeules J, Piguet V.

Rev Med Suisse. 2015 Jun 24;11(480):1390, 1392-4. Review. French.

PMID:
26267945
44.

[Prescription of antidepressants in the treatment of pain: role of pharmacogenetics].

Rodieux F, Piguet V, Berney P, Desmeules J, Besson M.

Rev Med Suisse. 2015 Jun 24;11(480):1374-9. Review. French.

PMID:
26267942
45.

The effect of dose on the safety and immunogenicity of the VSV Ebola candidate vaccine: a randomised double-blind, placebo-controlled phase 1/2 trial.

Huttner A, Dayer JA, Yerly S, Combescure C, Auderset F, Desmeules J, Eickmann M, Finckh A, Goncalves AR, Hooper JW, Kaya G, Krähling V, Kwilas S, Lemaître B, Matthey A, Silvera P, Becker S, Fast PE, Moorthy V, Kieny MP, Kaiser L, Siegrist CA; VSV-Ebola Consortium.

Lancet Infect Dis. 2015 Oct;15(10):1156-1166. doi: 10.1016/S1473-3099(15)00154-1. Epub 2015 Aug 4.

46.

Prescribing Generic Medication in Chronic Musculoskeletal Pain Patients: An Issue of Representations, Trust, and Experience in a Swiss Cohort.

Piguet V, D'Incau S, Besson M, Desmeules J, Cedraschi C.

PLoS One. 2015 Aug 3;10(8):e0134661. doi: 10.1371/journal.pone.0134661. eCollection 2015.

47.

A phase IIa randomized clinical study testing GNbAC1, a humanized monoclonal antibody against the envelope protein of multiple sclerosis associated endogenous retrovirus in multiple sclerosis patients - a twelve month follow-up.

Derfuss T, Curtin F, Guebelin C, Bridel C, Rasenack M, Matthey A, Du Pasquier R, Schluep M, Desmeules J, Lang AB, Perron H, Faucard R, Porchet H, Hartung HP, Kappos L, Lalive PH.

J Neuroimmunol. 2015 Aug 15;285:68-70. doi: 10.1016/j.jneuroim.2015.05.019. Epub 2015 May 20.

PMID:
26198921
48.

Evidence-Based Choice of P2Y12 Inhibitors in End Stage Renal Disease Patients: A Mini-Review.

Bouatou Y, Samer CF, Fontana P, Daali Y, Desmeules J.

Curr Drug Metab. 2015;16(2):97-104. Review.

PMID:
26179606
49.

Markers of Individual Drug Metabolism: Towards the Development of a Personalized Antidepressant Prescription.

Lloret-Linares C, Bellivier F, Haffen E, Aubry JM, Daali Y, Heron K, Berney P, Desmeules J, Besson M.

Curr Drug Metab. 2015;16(1):17-45. Review.

PMID:
26152128
50.

Drug-related problems identification in general internal medicine: The impact and role of the clinical pharmacist and pharmacologist.

Guignard B, Bonnabry P, Perrier A, Dayer P, Desmeules J, Samer CF.

Eur J Intern Med. 2015 Jul;26(6):399-406. doi: 10.1016/j.ejim.2015.05.012. Epub 2015 Jun 9.

PMID:
26066400

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