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Items: 1 to 50 of 115

1.

Encephalopathy induced by Alzheimer brain inoculation in a non-human primate.

Gary C, Lam S, Hérard AS, Koch JE, Petit F, Gipchtein P, Sawiak SJ, Caillierez R, Eddarkaoui S, Colin M, Aujard F, Deslys JP; French Neuropathology Network, Brouillet E, Buée L, Comoy EE, Pifferi F, Picq JL, Dhenain M.

Acta Neuropathol Commun. 2019 Sep 4;7(1):126. doi: 10.1186/s40478-019-0771-x.

2.

Small-molecule induction of Aβ-42 peptide production in human cerebral organoids to model Alzheimer's disease associated phenotypes.

Pavoni S, Jarray R, Nassor F, Guyot AC, Cottin S, Rontard J, Mikol J, Mabondzo A, Deslys JP, Yates F.

PLoS One. 2018 Dec 17;13(12):e0209150. doi: 10.1371/journal.pone.0209150. eCollection 2018.

3.

Unexpected prion phenotypes in experimentally transfused animals: predictive models for humans?

Comoy EE, Mikol J, Deslys JP.

Prion. 2018 Aug 16:1-8. doi: 10.1080/19336896.2018.1505399. [Epub ahead of print]

4.

Hemoglobin mRNA Changes in the Frontal Cortex of Patients with Neurodegenerative Diseases.

Vanni S, Zattoni M, Moda F, Giaccone G, Tagliavini F, Haïk S, Deslys JP, Zanusso G, Ironside JW, Carmona M, Ferrer I, Kovacs GG, Legname G.

Front Neurosci. 2018 Jan 22;12:8. doi: 10.3389/fnins.2018.00008. eCollection 2018.

5.

Differential overexpression of SERPINA3 in human prion diseases.

Vanni S, Moda F, Zattoni M, Bistaffa E, De Cecco E, Rossi M, Giaccone G, Tagliavini F, Haïk S, Deslys JP, Zanusso G, Ironside JW, Ferrer I, Kovacs GG, Legname G.

Sci Rep. 2017 Nov 15;7(1):15637. doi: 10.1038/s41598-017-15778-8.

6.

Experimental transfusion of variant CJD-infected blood reveals previously uncharacterised prion disorder in mice and macaque.

Comoy EE, Mikol J, Jaffré N, Lebon V, Levavasseur E, Streichenberger N, Sumian C, Perret-Liaudet A, Eloit M, Andreoletti O, Haïk S, Hantraye P, Deslys JP.

Nat Commun. 2017 Nov 2;8(1):1268. doi: 10.1038/s41467-017-01347-0.

7.

Transmission of scrapie prions to primate after an extended silent incubation period.

Comoy EE, Mikol J, Luccantoni-Freire S, Correia E, Lescoutra-Etchegaray N, Durand V, Dehen C, Andreoletti O, Casalone C, Richt JA, Greenlee JJ, Baron T, Benestad SL, Brown P, Deslys JP.

Sci Rep. 2015 Jun 30;5:11573. doi: 10.1038/srep11573.

8.

Evaluation of the protection of primates transfused with variant Creutzfeldt-Jakob disease-infected blood products filtered with prion removal devices: a 5-year update.

Lescoutra-Etchegaray N, Jaffré N, Sumian C, Durand V, Correia E, Mikol J, Luccantoni-Freire S, Culeux A, Deslys JP, Comoy EE.

Transfusion. 2015 Jun;55(6):1231-41. doi: 10.1111/trf.12999. Epub 2015 Feb 3.

PMID:
25647476
9.

Synthetic scrapie infectivity: interaction between recombinant PrP and scrapie brain-derived RNA.

Simoneau S, Thomzig A, Ruchoux MM, Vignier N, Daus ML, Poleggi A, Lebon P, Freire S, Durand V, Graziano S, Galeno R, Cardone F, Comoy E, Pocchiari M, Beekes M, Deslys JP, Fournier JG.

Virulence. 2015;6(2):132-44. doi: 10.4161/21505594.2014.989795. Epub 2015 Jan 13.

10.

The prion protein is critical for DNA repair and cell survival after genotoxic stress.

Bravard A, Auvré F, Fantini D, Bernardino-Sgherri J, Sissoëff L, Daynac M, Xu Z, Etienne O, Dehen C, Comoy E, Boussin FD, Tell G, Deslys JP, Radicella JP.

Nucleic Acids Res. 2015 Jan;43(2):904-16. doi: 10.1093/nar/gku1342. Epub 2014 Dec 24.

11.

Sensitive detection of aggregated prion protein via proximity ligation.

Hammond M, Wik L, Deslys JP, Comoy E, Linné T, Landegren U, Kamali-Moghaddam M.

Prion. 2014;8(3):261-5. doi: 10.4161/pri.32231.

12.

Blood reference materials from macaques infected with variant Creutzfeldt-Jakob disease agent.

McDowell KL, Nag N, Franco Z, Bu M, Piccardo P, Cervenak J, Deslys JP, Comoy E, Asher DM, Gregori L.

Transfusion. 2015 Feb;55(2):405-12. doi: 10.1111/trf.12841. Epub 2014 Aug 25.

PMID:
25154296
13.

Preclinical detection of variant CJD and BSE prions in blood.

Lacroux C, Comoy E, Moudjou M, Perret-Liaudet A, Lugan S, Litaise C, Simmons H, Jas-Duval C, Lantier I, Béringue V, Groschup M, Fichet G, Costes P, Streichenberger N, Lantier F, Deslys JP, Vilette D, Andréoletti O.

PLoS Pathog. 2014 Jun 12;10(6):e1004202. doi: 10.1371/journal.ppat.1004202. eCollection 2014 Jun.

14.

Removal of exogenous prion infectivity in leukoreduced red blood cells unit by a specific filter designed for human transfusion.

Lescoutra-Etchegaray N, Sumian C, Culeux A, Durand V, Gurgel PV, Deslys JP, Comoy EE.

Transfusion. 2014 Apr;54(4):1037-45. doi: 10.1111/trf.12420. Epub 2013 Oct 10.

PMID:
24117735
15.

Cleaning, disinfection and sterilization of surface prion contamination.

McDonnell G, Dehen C, Perrin A, Thomas V, Igel-Egalon A, Burke PA, Deslys JP, Comoy E.

J Hosp Infect. 2013 Dec;85(4):268-73. doi: 10.1016/j.jhin.2013.08.003. Epub 2013 Sep 8.

PMID:
24074640
16.

Decontamination of prions in a plasma product manufacturing environment.

Bellon A, Comoy E, Simoneau S, Mornac S, Dehen C, Perrin A, Arzel A, Arrabal S, Baron H, Laude H, You B, Deslys JP, Flan B.

Transfusion. 2014 Apr;54(4):1028-36. doi: 10.1111/trf.12381. Epub 2013 Aug 27.

PMID:
24032663
17.

Evaluation of the zoonotic potential of transmissible mink encephalopathy.

Comoy EE, Mikol J, Ruchoux MM, Durand V, Luccantoni-Freire S, Dehen C, Correia E, Casalone C, Richt JA, Greenlee JJ, Torres JM, Brown P, Deslys JP.

Pathogens. 2013 Jul 30;2(3):520-32. doi: 10.3390/pathogens2030520.

18.

Creutzfeldt-Jakob disease with unusually extensive neuropathology in a child treated with native human growth hormone.

Mikol J, Deslys JP, Zou WQ, Xiao W, Brown P, Budka H, Goutieres F.

Clin Neuropathol. 2012 May-Jun;31(3):127-34.

19.

Dual conformation of H2H3 domain of prion protein in mammalian cells.

Xu Z, Prigent S, Deslys JP, Rezaei H.

J Biol Chem. 2011 Nov 18;286(46):40060-8. doi: 10.1074/jbc.M111.275255. Epub 2011 Sep 12.

20.

Mechanistic insights into cellular alteration of prion by poly-D-lysine: the role of H2H3 domain.

Xu Z, Adrover M, Pastore A, Prigent S, Mouthon F, Comoy E, Rezaei H, Deslys JP.

FASEB J. 2011 Oct;25(10):3426-35. doi: 10.1096/fj.11-187534. Epub 2011 Jun 22.

PMID:
21697549
21.

Prion dynamics with size dependency-strain phenomena.

Calvez V, Lenuzza N, Doumic M, Deslys JP, Mouthon F, Perthame B.

J Biol Dyn. 2010 Jan;4(1):28-42. doi: 10.1080/17513750902935208.

PMID:
22881069
22.

New inhibitors of prion replication that target the amyloid precursor.

Charvériat M, Reboul M, Wang Q, Picoli C, Lenuzza N, Montagnac A, Nhiri N, Jacquet E, Guéritte F, Lallemand JY, Deslys JP, Mouthon F.

J Gen Virol. 2009 May;90(Pt 5):1294-301. doi: 10.1099/vir.0.009084-0. Epub 2009 Mar 4.

PMID:
19264641
23.

Size distribution dependence of prion aggregates infectivity.

Calvez V, Lenuzza N, Oelz D, Deslys JP, Laurent P, Mouthon F, Perthame B.

Math Biosci. 2009 Jan;217(1):88-99. doi: 10.1016/j.mbs.2008.10.007. Epub 2008 Nov 1.

PMID:
19000701
24.

Atypical BSE (BASE) transmitted from asymptomatic aging cattle to a primate.

Comoy EE, Casalone C, Lescoutra-Etchegaray N, Zanusso G, Freire S, Marcé D, Auvré F, Ruchoux MM, Ferrari S, Monaco S, Salès N, Caramelli M, Leboulch P, Brown P, Lasmézas CI, Deslys JP.

PLoS One. 2008 Aug 20;3(8):e3017. doi: 10.1371/journal.pone.0003017.

25.

Increase of monoamine oxidase-B activity in the brain of scrapie-infected hamsters.

Adjou KT, Dilda P, Aumond P, Gueddari S, Deslys JP, Dormont D, Seman M.

Neurochem Int. 2008 Jun;52(8):1416-21. doi: 10.1016/j.neuint.2008.03.002. Epub 2008 Mar 18.

PMID:
18442871
26.

Ultrastructural evidence that ependymal cells are infected in experimental scrapie.

Fournier JG, Adjou K, Grigoriev V, Deslys JP.

Acta Neuropathol. 2008 Jun;115(6):643-50. doi: 10.1007/s00401-008-0365-3. Epub 2008 Mar 28.

PMID:
18369649
27.

BIODECON - European project on plasma inactivation of bacteria and biomolecules.

Benedikt J, Raballand V, Halfmann H, Awakowicz P, von Keudell A, Kylian O, Hasiwa M, Rossi F, Muranyi P, Wunderlich J, Comoy E, Schell J, Deslys JP.

GMS Krankenhhyg Interdiszip. 2008 Mar 11;3(1):Doc04. No abstract available.

28.

Time-course studies of 14-3-3 protein isoforms in cerebrospinal fluid and brain of primates after oral or intracerebral infection with bovine spongiform encephalopathy agent.

Yutzy B, Holznagel E, Coulibaly C, Stuke A, Hahmann U, Deslys JP, Hunsmann G, Löwer J.

J Gen Virol. 2007 Dec;88(Pt 12):3469-78.

PMID:
18024918
29.

Prion inactivation using a new gaseous hydrogen peroxide sterilisation process.

Fichet G, Antloga K, Comoy E, Deslys JP, McDonnell G.

J Hosp Infect. 2007 Nov;67(3):278-86. Epub 2007 Oct 22.

PMID:
17942185
30.

Structure-activity studies of heparan mimetic polyanions for anti-prion therapies.

Ouidja MO, Petit E, Kerros ME, Ikeda Y, Morin C, Carpentier G, Barritault D, Brugère-Picoux J, Deslys JP, Adjou K, Papy-Garcia D.

Biochem Biophys Res Commun. 2007 Nov 9;363(1):95-100. Epub 2007 Aug 29.

PMID:
17826736
31.

Investigations of a prion infectivity assay to evaluate methods of decontamination.

Fichet G, Comoy E, Dehen C, Challier L, Antloga K, Deslys JP, McDonnell G.

J Microbiol Methods. 2007 Sep;70(3):511-8. Epub 2007 Jun 21.

PMID:
17640752
32.

Alpha-synuclein accumulates in the brain of scrapie-affected sheep and goats.

Adjou KT, Allix S, Ouidja MO, Backer S, Couquet C, Cornuejols MJ, Deslys JP, Brugère H, Brugère-Picoux J, El-Hachimi KH.

J Comp Pathol. 2007 Jul;137(1):78-81. doi: 10.1016/j.jcpa.2007.03.007. Epub 2007 Jun 4.

PMID:
17544436
33.

Comparison of CR36, a new heparan mimetic, and pentosan polysulfate in the treatment of prion diseases.

Larramendy-Gozalo C, Barret A, Daudigeos E, Mathieu E, Antonangeli L, Riffet C, Petit E, Papy-Garcia D, Barritault D, Brown P, Deslys JP.

J Gen Virol. 2007 Mar;88(Pt 3):1062-7.

PMID:
17325382
34.

Prion infection-impaired functional blocks identified by proteomics enlighten the targets and the curing pathways of an anti-prion drug.

Chich JF, Schaeffer B, Bouin AP, Mouthon F, Labas V, Larramendy C, Deslys JP, Grosclaude J.

Biochim Biophys Acta. 2007 Jan;1774(1):154-67. Epub 2006 Nov 7.

PMID:
17174161
35.

PrPTSE distribution in a primate model of variant, sporadic, and iatrogenic Creutzfeldt-Jakob disease.

Herzog C, Rivière J, Lescoutra-Etchegaray N, Charbonnier A, Leblanc V, Salès N, Deslys JP, Lasmézas CI.

J Virol. 2005 Nov;79(22):14339-45.

36.

Role of gut macrophages in mice orally contaminated with scrapie or BSE.

Maignien T, Shakweh M, Calvo P, Marcé D, Salès N, Fattal E, Deslys JP, Couvreur P, Lasmezas CI.

Int J Pharm. 2005 Jul 25;298(2):293-304.

PMID:
15964722
37.

[Screening tests for animal TSE: present and future].

Deslys JP, Grassi J.

Pathol Biol (Paris). 2005 May;53(4):221-8. Review. French.

PMID:
15850956
38.

BSE agent signatures in a goat.

Eloit M, Adjou K, Coulpier M, Fontaine JJ, Hamel R, Lilin T, Messiaen S, Andreoletti O, Baron T, Bencsik A, Biacabe AG, Beringue V, Laude H, Le Dur A, Vilotte JL, Comoy E, Deslys JP, Grassi J, Simon S, Lantier F, Sarradin P.

Vet Rec. 2005 Apr 16;156(16):523-4. No abstract available. Erratum in: Vet Rec. 2005 May 7;156(19):620.

PMID:
15833975
39.

Risk of oral infection with bovine spongiform encephalopathy agent in primates.

Lasmézas CI, Comoy E, Hawkins S, Herzog C, Mouthon F, Konold T, Auvré F, Correia E, Lescoutra-Etchegaray N, Salès N, Wells G, Brown P, Deslys JP.

Lancet. 2005 Feb 26-Mar 4;365(9461):781-3.

PMID:
15733719
40.

Glycosylation-related gene expression in prion diseases: PrPSc accumulation in scrapie infected GT1 cells depends on beta-1,4-linked GalNAc-4-SO4 hyposulfation.

Barret A, Forestier L, Deslys JP, Julien R, Gallet PF.

J Biol Chem. 2005 Mar 18;280(11):10516-23. Epub 2005 Jan 4.

41.

Novel methods for disinfection of prion-contaminated medical devices.

Fichet G, Comoy E, Duval C, Antloga K, Dehen C, Charbonnier A, McDonnell G, Brown P, Lasmézas CI, Deslys JP.

Lancet. 2004 Aug 7-13;364(9433):521-6.

PMID:
15302195
42.
43.

Tissue distribution of bovine spongiform encephalopathy agent in primates after intravenous or oral infection.

Herzog C, Salès N, Etchegaray N, Charbonnier A, Freire S, Dormont D, Deslys JP, Lasmézas CI.

Lancet. 2004 Feb 7;363(9407):422-8.

PMID:
14962521
44.

Properties of a disease-specific prion probe.

Gorochov G, Deslys JP.

Nat Med. 2004 Jan;10(1):11; author reply 11-2. No abstract available.

PMID:
14702617
45.

A novel generation of heparan sulfate mimetics for the treatment of prion diseases.

Adjou KT, Simoneau S, Salès N, Lamoury F, Dormont D, Papy-Garcia D, Barritault D, Deslys JP, Lasmézas CI.

J Gen Virol. 2003 Sep;84(Pt 9):2595-603.

PMID:
12917481
46.

Evaluation of quinacrine treatment for prion diseases.

Barret A, Tagliavini F, Forloni G, Bate C, Salmona M, Colombo L, De Luigi A, Limido L, Suardi S, Rossi G, Auvré F, Adjou KT, Salès N, Williams A, Lasmézas C, Deslys JP.

J Virol. 2003 Aug;77(15):8462-9.

47.

[Prions and risks for blood transfusion: the situation in 2003].

Deslys JP.

Transfus Clin Biol. 2003 Jun;10(3):113-25. Review. French.

PMID:
12798843
48.

[Disinfection of gas-permeable contact lenses against prions].

Comoy E, Bonnevalle C, Métais A, Auvré F, Letessier F, Lamoury F, Spittler J, Dormont D, Deslys JP.

J Fr Ophtalmol. 2003 Mar;26(3):233-9. French.

49.

Different isoforms of the non-integrin laminin receptor are present in mouse brain and bind PrP.

Simoneau S, Haïk S, Leucht C, Dormont D, Deslys JP, Weiss S, Lasmézas C.

Biol Chem. 2003 Feb;384(2):243-6.

PMID:
12675517
50.

Effects of the polyene antibiotic derivative MS-8209 on the astrocyte lysosomal system of scrapie-infected hamsters.

Grigoriev VB, Adjou KT, Salès N, Simoneau S, Deslys JP, Seman M, Dormont D, Fournier JG.

J Mol Neurosci. 2002 Jun;18(3):271-81.

PMID:
12059046

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