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Items: 1 to 50 of 91

1.

Short telomere syndromes cause a primary T cell immunodeficiency.

Wagner CL, Hanumanthu VS, Talbot CC Jr, Abraham RS, Hamm D, Gable DL, Kanakry CG, Applegate CD, Siliciano J, Jackson JB, Desiderio S, Alder JK, Luznik L, Armanios M.

J Clin Invest. 2018 Oct 22. pii: 120216. doi: 10.1172/JCI120216. [Epub ahead of print]

2.

The RAG-2 Inhibitory Domain Gates Accessibility Of The V(D)J Recombinase To Chromatin.

Ward A, Kumari G, Sen R, Desiderio S.

Mol Cell Biol. 2018 May 14. pii: MCB.00159-18. doi: 10.1128/MCB.00159-18. [Epub ahead of print]

PMID:
29760281
3.

Smoothened signaling in the mouse osteoblastoid lineage is required for efficient B lymphopoiesis.

Lu W, Dordai D, Huso D, Desiderio S.

Blood. 2018 Jan 18;131(3):323-327. doi: 10.1182/blood-2017-06-793539. Epub 2017 Nov 22.

PMID:
29167177
4.

High-resolution melting analysis (HRM) for mutational screening of Dnajc17 gene in patients affected by thyroid dysgenesis.

Nettore IC, Desiderio S, De Nisco E, Cacace V, Albano L, Improda N, Ungaro P, Salerno M, Colao A, Macchia PE.

J Endocrinol Invest. 2018 Jun;41(6):711-717. doi: 10.1007/s40618-017-0795-7. Epub 2017 Nov 20.

PMID:
29159607
5.

Selenium supplementation modulates apoptotic processes in thyroid follicular cells.

Nettore IC, De Nisco E, Desiderio S, Passaro C, Maione L, Negri M, Albano L, Pivonello R, Pivonello C, Portella G, Ungaro P, Colao A, Macchia PE.

Biofactors. 2017 May 6;43(3):415-423. doi: 10.1002/biof.1351. Epub 2017 Mar 2.

PMID:
28251705
6.

H3K4me3 induces allosteric conformational changes in the DNA-binding and catalytic regions of the V(D)J recombinase.

Bettridge J, Na CH, Pandey A, Desiderio S.

Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):1904-1909. doi: 10.1073/pnas.1615727114. Epub 2017 Feb 7.

7.

Pumping the breaks on B cell development.

Desiderio S.

J Exp Med. 2016 Feb 8;213(2):140. doi: 10.1084/jem.2132insight1. No abstract available.

8.

Prdm12 specifies V1 interneurons through cross-repressive interactions with Dbx1 and Nkx6 genes in Xenopus.

Thélie A, Desiderio S, Hanotel J, Quigley I, Van Driessche B, Rodari A, Borromeo MD, Kricha S, Lahaye F, Croce J, Cerda-Moya G, Ordoño Fernandez J, Bolle B, Lewis KE, Sander M, Pierani A, Schubert M, Johnson JE, Kintner CR, Pieler T, Van Lint C, Henningfeld KA, Bellefroid EJ, Van Campenhout C.

Development. 2015 Oct 1;142(19):3416-28. doi: 10.1242/dev.121871.

9.

An autoregulatory mechanism imposes allosteric control on the V(D)J recombinase by histone H3 methylation.

Lu C, Ward A, Bettridge J, Liu Y, Desiderio S.

Cell Rep. 2015 Jan 6;10(1):29-38. doi: 10.1016/j.celrep.2014.12.001. Epub 2014 Dec 24.

10.

Fine mapping of V(D)J recombinase mediated rearrangements in human lymphoid malignancies.

Halper-Stromberg E, Steranka J, Giraldo-Castillo N, Fuller T, Desiderio S, Burns KH.

BMC Genomics. 2013 Aug 19;14:565. doi: 10.1186/1471-2164-14-565.

11.

53BP1 is limiting for NHEJ repair in ATM-deficient model systems that are subjected to oncogenic stress or radiation.

Rybanska-Spaeder I, Reynolds TL, Chou J, Prakash M, Jefferson T, Huso DL, Desiderio S, Franco S.

Mol Cancer Res. 2013 Oct;11(10):1223-34. doi: 10.1158/1541-7786.MCR-13-0252-T. Epub 2013 Jul 15.

12.

Stat3β mitigates development of atherosclerosis in apolipoprotein E-deficient mice.

Lee J, Baldwin WM 3rd, Lee CY, Desiderio S.

J Mol Med (Berl). 2013 Aug;91(8):965-76. doi: 10.1007/s00109-013-1013-5. Epub 2013 Apr 26.

13.

Construction of human activity-based phosphorylation networks.

Newman RH, Hu J, Rho HS, Xie Z, Woodard C, Neiswinger J, Cooper C, Shirley M, Clark HM, Hu S, Hwang W, Jeong JS, Wu G, Lin J, Gao X, Ni Q, Goel R, Xia S, Ji H, Dalby KN, Birnbaum MJ, Cole PA, Knapp S, Ryazanov AG, Zack DJ, Blackshaw S, Pawson T, Gingras AC, Desiderio S, Pandey A, Turk BE, Zhang J, Zhu H, Qian J.

Mol Syst Biol. 2013;9:655. doi: 10.1038/msb.2013.12.

14.

The transcriptional repressor NKAP is required for the development of iNKT cells.

Thapa P, Das J, McWilliams D, Shapiro M, Sundsbak R, Nelson-Holte M, Tangen S, Anderson J, Desiderio S, Hiebert S, Sant'angelo DB, Shapiro VS.

Nat Commun. 2013;4:1582. doi: 10.1038/ncomms2580.

15.

Non-cell-autonomous hedgehog signaling promotes murine B lymphopoiesis from hematopoietic progenitors.

Cooper CL, Hardy RR, Reth M, Desiderio S.

Blood. 2012 Jun 7;119(23):5438-48. doi: 10.1182/blood-2011-12-397976. Epub 2012 Apr 18.

16.

Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model.

Greenblatt S, Li L, Slape C, Nguyen B, Novak R, Duffield A, Huso D, Desiderio S, Borowitz MJ, Aplan P, Small D.

Blood. 2012 Mar 22;119(12):2883-94. doi: 10.1182/blood-2011-10-382283. Epub 2012 Feb 8.

17.

Coupling of V(D)J recombination to the cell cycle suppresses genomic instability and lymphoid tumorigenesis.

Zhang L, Reynolds TL, Shan X, Desiderio S.

Immunity. 2011 Feb 25;34(2):163-74. doi: 10.1016/j.immuni.2011.02.003.

18.

Defective nonhomologous end joining blocks B-cell development in FLT3/ITD mice.

Li L, Zhang L, Fan J, Greenberg K, Desiderio S, Rassool FV, Small D.

Blood. 2011 Mar 17;117(11):3131-9. doi: 10.1182/blood-2010-05-286070. Epub 2011 Jan 12.

19.

Temporal and spatial regulatory functions of the V(D)J recombinase.

Desiderio S.

Semin Immunol. 2010 Dec;22(6):362-9. doi: 10.1016/j.smim.2010.09.001. Epub 2010 Oct 30. Review.

PMID:
21036059
20.

NetPath: a public resource of curated signal transduction pathways.

Kandasamy K, Mohan SS, Raju R, Keerthikumar S, Kumar GS, Venugopal AK, Telikicherla D, Navarro JD, Mathivanan S, Pecquet C, Gollapudi SK, Tattikota SG, Mohan S, Padhukasahasram H, Subbannayya Y, Goel R, Jacob HK, Zhong J, Sekhar R, Nanjappa V, Balakrishnan L, Subbaiah R, Ramachandra YL, Rahiman BA, Prasad TS, Lin JX, Houtman JC, Desiderio S, Renauld JC, Constantinescu SN, Ohara O, Hirano T, Kubo M, Singh S, Khatri P, Draghici S, Bader GD, Sander C, Leonard WJ, Pandey A.

Genome Biol. 2010 Jan 12;11(1):R3. doi: 10.1186/gb-2010-11-1-r3.

21.
22.

Phospholipase C-gamma binds directly to the Na+/H+ exchanger 3 and is required for calcium regulation of exchange activity.

Zachos NC, van Rossum DB, Li X, Caraveo G, Sarker R, Cha B, Mohan S, Desiderio S, Patterson RL, Donowitz M.

J Biol Chem. 2009 Jul 17;284(29):19437-44. doi: 10.1074/jbc.M109.006098. Epub 2009 May 27.

23.

Along came a spider: AID escapes a microRNA web.

Desiderio S.

Immunity. 2008 May;28(5):596-8. doi: 10.1016/j.immuni.2008.04.012.

24.

The Paf1 complex promotes displacement of histones upon rapid induction of transcription by RNA polymerase II.

Marton HA, Desiderio S.

BMC Mol Biol. 2008 Jan 14;9:4. doi: 10.1186/1471-2199-9-4.

25.

A plant homeodomain in RAG-2 that binds Hypermethylated lysine 4 of histone H3 is necessary for efficient antigen-receptor-gene rearrangement.

Liu Y, Subrahmanyam R, Chakraborty T, Sen R, Desiderio S.

Immunity. 2007 Oct;27(4):561-71. Epub 2007 Oct 11.

26.

hCTR9, a component of Paf1 complex, participates in the transcription of interleukin 6-responsive genes through regulation of STAT3-DNA interactions.

Youn MY, Yoo HS, Kim MJ, Hwang SY, Choi Y, Desiderio SV, Yoo JY.

J Biol Chem. 2007 Nov 30;282(48):34727-34. Epub 2007 Oct 1.

27.

Action of TFII-I outside the nucleus as an inhibitor of agonist-induced calcium entry.

Caraveo G, van Rossum DB, Patterson RL, Snyder SH, Desiderio S.

Science. 2006 Oct 6;314(5796):122-5.

28.

Ubiquitylation of RAG-2 by Skp2-SCF links destruction of the V(D)J recombinase to the cell cycle.

Jiang H, Chang FC, Ross AE, Lee J, Nakayama K, Nakayama K, Desiderio S.

Mol Cell. 2005 Jun 10;18(6):699-709.

29.

Vascular endothelial growth factor receptor-2: counter-regulation by the transcription factors, TFII-I and TFII-IRD1.

Jackson TA, Taylor HE, Sharma D, Desiderio S, Danoff SK.

J Biol Chem. 2005 Aug 19;280(33):29856-63. Epub 2005 Jun 7.

30.
31.

Mimicry of pre-B cell receptor signaling by activation of the tyrosine kinase Blk.

Tretter T, Ross AE, Dordai DI, Desiderio S.

J Exp Med. 2003 Dec 15;198(12):1863-73. Epub 2003 Dec 8.

32.
34.

A genome-wide analysis of the acute-phase response and its regulation by Stat3beta.

Desiderio S, Yoo JY.

Ann N Y Acad Sci. 2003 Apr;987:280-4. Review.

PMID:
12727653
35.

Innate and acquired immunity intersect in a global view of the acute-phase response.

Yoo JY, Desiderio S.

Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1157-62. Epub 2003 Jan 22.

36.

cGMP-dependent protein kinase I beta physically and functionally interacts with the transcriptional regulator TFII-I.

Casteel DE, Zhuang S, Gudi T, Tang J, Vuica M, Desiderio S, Pilz RB.

J Biol Chem. 2002 Aug 30;277(35):32003-14. Epub 2002 Jun 24.

37.
38.

Identification of phosphorylation sites for Bruton's tyrosine kinase within the transcriptional regulator BAP/TFII-I.

Egloff AM, Desiderio S.

J Biol Chem. 2001 Jul 27;276(30):27806-15. Epub 2001 May 23.

40.

Synergistic activity of STAT3 and c-Jun at a specific array of DNA elements in the alpha 2-macroglobulin promoter.

Yoo JY, Wang W, Desiderio S, Nathans D.

J Biol Chem. 2001 Jul 13;276(28):26421-9. Epub 2001 Apr 23.

41.

Somatic evolution of antibody specificity: setting the clock forward.

Desiderio S.

Nat Immunol. 2000 Dec;1(6):463-4. No abstract available.

PMID:
11101864
42.

The B-cell-specific Src-family kinase Blk is dispensable for B-cell development and activation.

Texido G, Su IH, Mecklenbräuker I, Saijo K, Malek SN, Desiderio S, Rajewsky K, Tarakhovsky A.

Mol Cell Biol. 2000 Feb;20(4):1227-33.

43.
44.

Signaling pathways that control V(D)J recombination.

Desiderio S, Lee J.

Curr Top Microbiol Immunol. 2000;245(2):31-56. Review. No abstract available.

PMID:
10533317
45.
47.

Malignant transformation of early lymphoid progenitors in mice expressing an activated Blk tyrosine kinase.

Malek SN, Dordai DI, Reim J, Dintzis H, Desiderio S.

Proc Natl Acad Sci U S A. 1998 Jun 23;95(13):7351-6.

48.
49.

Role of Btk in B cell development and signaling.

Desiderio S.

Curr Opin Immunol. 1997 Aug;9(4):534-40. Review.

PMID:
9287186

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