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Items: 24

1.

ATM and PRDM9 regulate SPO11-bound recombination intermediates during meiosis.

Paiano J, Wu W, Yamada S, Sciascia N, Callen E, Paola Cotrim A, Deshpande RA, Maman Y, Day A, Paull TT, Nussenzweig A.

Nat Commun. 2020 Feb 12;11(1):857. doi: 10.1038/s41467-020-14654-w.

2.

DNA-dependent protein kinase promotes DNA end processing by MRN and CtIP.

Deshpande RA, Myler LR, Soniat MM, Makharashvili N, Lee L, Lees-Miller SP, Finkelstein IJ, Paull TT.

Sci Adv. 2020 Jan 8;6(2):eaay0922. doi: 10.1126/sciadv.aay0922. eCollection 2020 Jan.

3.

Dual-Band Metasurfaces Using Multiple Gap-Surface Plasmon Resonances.

Deshpande RA, Ding F, Bozhevolnyi S.

ACS Appl Mater Interfaces. 2020 Jan 8;12(1):1250-1256. doi: 10.1021/acsami.9b15410. Epub 2019 Dec 20.

PMID:
31826607
4.

Purification and Biophysical Characterization of the Mre11-Rad50-Nbs1 Complex.

Myler LR, Soniat MM, Zhang X, Deshpande RA, Paull TT, Finkelstein IJ.

Methods Mol Biol. 2019;2004:269-287. doi: 10.1007/978-1-4939-9520-2_20.

5.

Sudden cardiac arrest on 5th day after coronary artery bypass graft surgery: Diagnostic dilemma.

Choudhari MS, Sonkusale MI, Deshpande RA.

Ann Card Anaesth. 2018 Jul-Sep;21(3):341-342. doi: 10.4103/aca.ACA_214_17. No abstract available.

6.

Inadvertent diversion of inferior vena cava to left atrium after repair of atrial septal defect - Early diagnosis and correction of error: role of intraoperative transesophageal echocardiography.

Choudhari MS, Charan N, Sonkusale MI, Deshpande RA.

Ann Card Anaesth. 2017 Oct-Dec;20(4):481-482. doi: 10.4103/aca.ACA_83_17. No abstract available.

7.

Genetic Separation of Sae2 Nuclease Activity from Mre11 Nuclease Functions in Budding Yeast.

Arora S, Deshpande RA, Budd M, Campbell J, Revere A, Zhang X, Schmidt KH, Paull TT.

Mol Cell Biol. 2017 Nov 28;37(24). pii: e00156-17. doi: 10.1128/MCB.00156-17. Print 2017 Dec 15.

8.

Single-Molecule Imaging Reveals How Mre11-Rad50-Nbs1 Initiates DNA Break Repair.

Myler LR, Gallardo IF, Soniat MM, Deshpande RA, Gonzalez XB, Kim Y, Paull TT, Finkelstein IJ.

Mol Cell. 2017 Sep 7;67(5):891-898.e4. doi: 10.1016/j.molcel.2017.08.002. Epub 2017 Aug 31.

9.

Rad50 ATPase activity is regulated by DNA ends and requires coordination of both active sites.

Deshpande RA, Lee JH, Paull TT.

Nucleic Acids Res. 2017 May 19;45(9):5255-5268. doi: 10.1093/nar/gkx173.

10.

Mre11 Is Essential for the Removal of Lethal Topoisomerase 2 Covalent Cleavage Complexes.

Hoa NN, Shimizu T, Zhou ZW, Wang ZQ, Deshpande RA, Paull TT, Akter S, Tsuda M, Furuta R, Tsutsui K, Takeda S, Sasanuma H.

Mol Cell. 2016 Dec 1;64(5):1010. doi: 10.1016/j.molcel.2016.11.028. No abstract available.

11.

Nbs1 Converts the Human Mre11/Rad50 Nuclease Complex into an Endo/Exonuclease Machine Specific for Protein-DNA Adducts.

Deshpande RA, Lee JH, Arora S, Paull TT.

Mol Cell. 2016 Nov 3;64(3):593-606. doi: 10.1016/j.molcel.2016.10.010.

12.

Mre11 Is Essential for the Removal of Lethal Topoisomerase 2 Covalent Cleavage Complexes.

Hoa NN, Shimizu T, Zhou ZW, Wang ZQ, Deshpande RA, Paull TT, Akter S, Tsuda M, Furuta R, Tsutsui K, Takeda S, Sasanuma H.

Mol Cell. 2016 Nov 3;64(3):580-592. doi: 10.1016/j.molcel.2016.10.011. Erratum in: Mol Cell. 2016 Dec 1;64(5):1010.

13.

ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling.

Deshpande RA, Williams GJ, Limbo O, Williams RS, Kuhnlein J, Lee JH, Classen S, Guenther G, Russell P, Tainer JA, Paull TT.

EMBO J. 2016 Apr 1;35(7):791. doi: 10.15252/embj.201694047. No abstract available.

14.

Differential Ratios of Omega Fatty Acids (AA/EPA+DHA) Modulate Growth, Lipid Peroxidation and Expression of Tumor Regulatory MARBPs in Breast Cancer Cell Lines MCF7 and MDA-MB-231.

Mansara PP, Deshpande RA, Vaidya MM, Kaul-Ghanekar R.

PLoS One. 2015 Sep 1;10(9):e0136542. doi: 10.1371/journal.pone.0136542. eCollection 2015.

15.

The Mre11/Rad50/Nbs1 complex: recent insights into catalytic activities and ATP-driven conformational changes.

Paull TT, Deshpande RA.

Exp Cell Res. 2014 Nov 15;329(1):139-47. doi: 10.1016/j.yexcr.2014.07.007. Epub 2014 Jul 9. Review. No abstract available.

16.

Catalytic and noncatalytic roles of the CtIP endonuclease in double-strand break end resection.

Makharashvili N, Tubbs AT, Yang SH, Wang H, Barton O, Zhou Y, Deshpande RA, Lee JH, Lobrich M, Sleckman BP, Wu X, Paull TT.

Mol Cell. 2014 Jun 19;54(6):1022-33. doi: 10.1016/j.molcel.2014.04.011. Epub 2014 May 15.

17.

ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling.

Deshpande RA, Williams GJ, Limbo O, Williams RS, Kuhnlein J, Lee JH, Classen S, Guenther G, Russell P, Tainer JA, Paull TT.

EMBO J. 2014 Mar 3;33(5):482-500. doi: 10.1002/embj.201386100. Epub 2014 Feb 3. Erratum in: EMBO J. 2016 Apr 1;35(7):791.

18.

Ataxia telangiectasia-mutated (ATM) kinase activity is regulated by ATP-driven conformational changes in the Mre11/Rad50/Nbs1 (MRN) complex.

Lee JH, Mand MR, Deshpande RA, Kinoshita E, Yang SH, Wyman C, Paull TT.

J Biol Chem. 2013 May 3;288(18):12840-51. doi: 10.1074/jbc.M113.460378. Epub 2013 Mar 22.

19.

Modes of interaction among yeast Nej1, Lif1 and Dnl4 proteins and comparison to human XLF, XRCC4 and Lig4.

Deshpande RA, Wilson TE.

DNA Repair (Amst). 2007 Oct 1;6(10):1507-16. Epub 2007 Jun 12.

20.
21.

The role of yeast DNA 3'-phosphatase Tpp1 and rad1/Rad10 endonuclease in processing spontaneous and induced base lesions.

Karumbati AS, Deshpande RA, Jilani A, Vance JR, Ramotar D, Wilson TE.

J Biol Chem. 2003 Aug 15;278(33):31434-43. Epub 2003 Jun 3.

22.

Equilibrium unfolding of RNase Rs from Rhizopus stolonifer: pH dependence of chemical and thermal denaturation.

Deshpande RA, Khan MI, Shankar V.

Biochim Biophys Acta. 2003 May 30;1648(1-2):184-94.

PMID:
12758161
23.

Ribonucleases from T2 family.

Deshpande RA, Shankar V.

Crit Rev Microbiol. 2002;28(2):79-122. Review.

PMID:
12109772
24.

Ribonuclease Rs from Rhizopus stolonifer: lowering of optimum temperature in the presence of urea.

Deshpande RA, Kumar AR, Khan MI, Shankar V.

Biochim Biophys Acta. 2001 Feb 9;1545(1-2):13-9.

PMID:
11342027

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