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MicroRNA-638 inhibits human airway smooth muscle cell proliferation and migration through targeting cyclin D1 and NOR1.

Wang H, Yao H, Yi B, Kazama K, Liu Y, Deshpande D, Zhang J, Sun J.

J Cell Physiol. 2018 Aug 4. doi: 10.1002/jcp.26930. [Epub ahead of print] Review.


Dysregulation of a novel miR-1825/TBCB/TUBA4A pathway in sporadic and familial ALS.

Helferich AM, Brockmann SJ, Reinders J, Deshpande D, Holzmann K, Brenner D, Andersen PM, Petri S, Thal DR, Michaelis J, Otto M, Just S, Ludolph AC, Danzer KM, Freischmidt A, Weishaupt JH.

Cell Mol Life Sci. 2018 Jul 20. doi: 10.1007/s00018-018-2873-1. [Epub ahead of print]


Apoptosis signal-regulating kinase 1 inhibition attenuates human airway smooth muscle growth and migration in chronic obstructive pulmonary disease.

Eapen MS, Kota A, Vindin H, McAlinden KD, Xenaki D, Oliver BG, Deshpande DA, Sohal SS, Sharma P.

Clin Sci (Lond). 2018 Jul 31;132(14):1615-1627. doi: 10.1042/CS20180398. Print 2018 Jul 31.


New targets for resolution of airway remodeling in obstructive lung diseases.

Nayak AP, Deshpande DA, Penn RB.

F1000Res. 2018 May 30;7. pii: F1000 Faculty Rev-680. doi: 10.12688/f1000research.14581.1. eCollection 2018. Review.


Implementation of failure mode and effective analysis for high dose rate brachytherapy at Tata Memorial Hospital, Mumbai, India.

Swamidas J, Khanna N, Mahantshetty U, Somesan V, Deshpande DD, Shrivastava SK.

Cancer Radiother. 2018 Jun;22(4):334-340. doi: 10.1016/j.canrad.2018.05.001. Epub 2018 May 30.


Novel splice-site variant of UCHL1 in an Indian family with autosomal recessive spastic paraplegia-79.

Das Bhowmik A, Patil SJ, Deshpande DV, Bhat V, Dalal A.

J Hum Genet. 2018 Aug;63(8):927-933. doi: 10.1038/s10038-018-0463-6. Epub 2018 May 7.


Monte Carlo Investigation of Photon Beam Characteristics and its Variation with Incident Electron Beam Parameters for Indigenous Medical Linear Accelerator.

Mishra S, Dixit PK, Selvam TP, Yavalkar SS, Deshpande DD.

J Med Phys. 2018 Jan-Mar;43(1):1-8. doi: 10.4103/jmp.JMP_125_17.


Improvement in Therapeutic Efficacy and Reduction in Cellular Toxicity: Introduction of a Novel Anti-PSMA-Conjugated Hybrid Antiandrogen Nanoparticle.

Thangavel C, Perepelyuk M, Boopathi E, Liu Y, Polischak S, Deshpande DA, Rafiq K, Dicker AP, Knudsen KE, Shoyele SA, Den RB.

Mol Pharm. 2018 May 7;15(5):1778-1790. doi: 10.1021/acs.molpharmaceut.7b01024. Epub 2018 Apr 4.


Commissioning and validation of commercial deformable image registration software for adaptive contouring.

Jamema SV, Phurailatpam R, Paul SN, Joshi K, Deshpande DD.

Phys Med. 2018 Mar;47:1-8. doi: 10.1016/j.ejmp.2018.01.013. Epub 2018 Feb 9.


CD38/cADPR Signaling Pathway in Airway Disease: Regulatory Mechanisms.

Deshpande DA, Guedes AGP, Graeff R, Dogan S, Subramanian S, Walseth TF, Kannan MS.

Mediators Inflamm. 2018 Feb 7;2018:8942042. doi: 10.1155/2018/8942042. eCollection 2018. Review.


Magnetic Resonance Image Guided Adaptive Brachytherapy in Locally Advanced Cervical Cancer: An Experience From a Tertiary Cancer Center in a Low and Middle Income Countries Setting.

Mahantshetty U, Krishnatry R, Hande V, Jamema S, Ghadi Y, Engineer R, Chopra S, Gurram L, Deshpande D, Shrviastava S.

Int J Radiat Oncol Biol Phys. 2017 Nov 1;99(3):608-617. doi: 10.1016/j.ijrobp.2017.06.010. Epub 2017 Jun 20.


Antibacterial and Sterilizing Effect of Benzylpenicillin in Tuberculosis.

Deshpande D, Srivastava S, Bendet P, Martin KR, Cirrincione KN, Lee PS, Pasipanodya JG, Dheda K, Gumbo T.

Antimicrob Agents Chemother. 2018 Jan 25;62(2). pii: e02232-17. doi: 10.1128/AAC.02232-17. Print 2018 Feb.


Familial choreoathetosis due to novel heterozygous mutation in PDE10A.

Narayanan DL, Deshpande D, Das Bhowmik A, Varma DR, Dalal A.

Am J Med Genet A. 2018 Jan;176(1):146-150. doi: 10.1002/ajmg.a.38507. Epub 2017 Nov 12.


Biased signaling of the proton-sensing receptor OGR1 by benzodiazepines.

Pera T, Deshpande DA, Ippolito M, Wang B, Gavrila A, Michael JV, Nayak AP, Tompkins E, Farrell E, Kroeze WK, Roth BL, Panettieri RA Jr, Benovic JL, An SS, Dulin NO, Penn RB.

FASEB J. 2018 Feb;32(2):862-874. doi: 10.1096/fj.201700555R. Epub 2018 Jan 4.


Homeostatic nuclear RAGE-ATM interaction is essential for efficient DNA repair.

Kumar V, Fleming T, Terjung S, Gorzelanny C, Gebhardt C, Agrawal R, Mall MA, Ranzinger J, Zeier M, Madhusudhan T, Ranjan S, Isermann B, Liesz A, Deshpande D, Häring HU, Biswas SK, Reynolds PR, Hammes HP, Peperkok R, Angel P, Herzig S, Nawroth PP.

Nucleic Acids Res. 2017 Oct 13;45(18):10595-10613. doi: 10.1093/nar/gkx705.


Meta-analyses and the evidence base for microbial outcomes in the treatment of pulmonary Mycobacterium avium-intracellulare complex disease.

Pasipanodya JG, Ogbonna D, Deshpande D, Srivastava S, Gumbo T.

J Antimicrob Chemother. 2017 Sep 1;72(suppl_2):i3-i19. doi: 10.1093/jac/dkx311. Review.


A programme to create short-course chemotherapy for pulmonary Mycobacterium avium disease based on pharmacokinetics/pharmacodynamics and mathematical forecasting.

Deshpande D, Srivastava S, Gumbo T.

J Antimicrob Chemother. 2017 Sep 1;72(suppl_2):i54-i60. doi: 10.1093/jac/dkx309.


A 'shock and awe' thioridazine and moxifloxacin combination-based regimen for pulmonary Mycobacterium avium-intracellulare complex disease.

Srivastava S, Deshpande D, Sherman CM, Gumbo T.

J Antimicrob Chemother. 2017 Sep 1;72(suppl_2):i43-i47. doi: 10.1093/jac/dkx308.


A novel ceftazidime/avibactam, rifabutin, tedizolid and moxifloxacin (CARTM) regimen for pulmonary Mycobacterium avium disease.

Deshpande D, Srivastava S, Pasipanodya JG, Lee PS, Gumbo T.

J Antimicrob Chemother. 2017 Sep 1;72(suppl_2):i48-i53. doi: 10.1093/jac/dkx307.


The discovery of ceftazidime/avibactam as an anti-Mycobacterium avium agent.

Deshpande D, Srivastava S, Chapagain ML, Lee PS, Cirrincione KN, Pasipanodya JG, Gumbo T.

J Antimicrob Chemother. 2017 Sep 1;72(suppl_2):i36-i42. doi: 10.1093/jac/dkx306.


Tedizolid is highly bactericidal in the treatment of pulmonary Mycobacterium avium complex disease.

Deshpande D, Srivastava S, Pasipanodya JG, Lee PS, Gumbo T.

J Antimicrob Chemother. 2017 Sep 1;72(suppl_2):i30-i35. doi: 10.1093/jac/dkx305.


Linezolid as treatment for pulmonary Mycobacterium avium disease.

Deshpande D, Srivastava S, Pasipanodya JG, Gumbo T.

J Antimicrob Chemother. 2017 Sep 1;72(suppl_2):i24-i29. doi: 10.1093/jac/dkx304.


Ceftazidime-avibactam has potent sterilizing activity against highly drug-resistant tuberculosis.

Deshpande D, Srivastava S, Chapagain M, Magombedze G, Martin KR, Cirrincione KN, Lee PS, Koeuth T, Dheda K, Gumbo T.

Sci Adv. 2017 Aug 30;3(8):e1701102. doi: 10.1126/sciadv.1701102. eCollection 2017 Aug.


Systematic Review and Meta-analyses of the Effect of Chemotherapy on Pulmonary Mycobacterium abscessus Outcomes and Disease Recurrence.

Pasipanodya JG, Ogbonna D, Ferro BE, Magombedze G, Srivastava S, Deshpande D, Gumbo T.

Antimicrob Agents Chemother. 2017 Oct 24;61(11). pii: e01206-17. doi: 10.1128/AAC.01206-17. Print 2017 Nov.


Change of target volume and its dosimetric impact during the course of accelerated partial breast irradiation using intraoperative multicatheter interstitial brachytherapy after open cavity surgery.

Upreti RR, Budrukkar A, Upreti U, Misra S, Wadasadawala T, Kohle S, Deshpande DD.

Brachytherapy. 2017 Sep - Oct;16(5):1028-1034. doi: 10.1016/j.brachy.2017.05.004. Epub 2017 Jun 7.


Linezolid Dose That Maximizes Sterilizing Effect While Minimizing Toxicity and Resistance Emergence for Tuberculosis.

Srivastava S, Magombedze G, Koeuth T, Sherman C, Pasipanodya JG, Raj P, Wakeland E, Deshpande D, Gumbo T.

Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e00751-17. doi: 10.1128/AAC.00751-17. Print 2017 Aug.


Interobserver variations of target volume delineation and its impact on irradiated volume in accelerated partial breast irradiation with intraoperative interstitial breast implant.

Upreti RR, Budrukkar A, Wadasadawala T, Misra S, Gurram L, Pathak R, Deshpande DD.

J Contemp Brachytherapy. 2017 Apr;9(2):139-145. doi: 10.5114/jcb.2017.66027. Epub 2017 Feb 14.


Multifunctional Effects of a Small-Molecule STAT3 Inhibitor on NASH and Hepatocellular Carcinoma in Mice.

Jung KH, Yoo W, Stevenson HL, Deshpande D, Shen H, Gagea M, Yoo SY, Wang J, Eckols TK, Bharadwaj U, Tweardy DJ, Beretta L.

Clin Cancer Res. 2017 Sep 15;23(18):5537-5546. doi: 10.1158/1078-0432.CCR-16-2253. Epub 2017 May 22.


Bitter taste receptor agonists alter mitochondrial function and induce autophagy in airway smooth muscle cells.

Pan S, Sharma P, Shah SD, Deshpande DA.

Am J Physiol Lung Cell Mol Physiol. 2017 Jul 1;313(1):L154-L165. doi: 10.1152/ajplung.00106.2017. Epub 2017 Apr 27.


Measurement of Total Scatter Factor for Stereotactic Cones with Plastic Scintillation Detector.

Chaudhari SH, Dobhal R, Kinhikar RA, Kadam SS, Deshpande DD.

J Med Phys. 2017 Jan-Mar;42(1):9-13. doi: 10.4103/jmp.JMP_114_16.


Bitter Taste Receptor Agonists Mitigate Features of Allergic Asthma in Mice.

Sharma P, Yi R, Nayak AP, Wang N, Tang F, Knight MJ, Pan S, Oliver B, Deshpande DA.

Sci Rep. 2017 Apr 11;7:46166. doi: 10.1038/srep46166.


Autophagy and airway fibrosis: Is there a link?

Kota A, Deshpande DA, Haghi M, Oliver B, Sharma P.

Version 2. F1000Res. 2017 Apr 3 [revised 2018 Jan 1];6:409. doi: 10.12688/f1000research.11236.2. eCollection 2017. Review.


CD38 in the pathogenesis of allergic airway disease: Potential therapeutic targets.

Deshpande DA, Guedes AG, Lund FE, Subramanian S, Walseth TF, Kannan MS.

Pharmacol Ther. 2017 Apr;172:116-126. doi: 10.1016/j.pharmthera.2016.12.002. Epub 2016 Dec 7. Review.


Clinical outcome of high-dose-rate interstitial brachytherapy in vulvar cancer: A single institutional experience.

Mahantshetty U, Naga P, Engineer R, Sastri S, Ghadi Y, Upreti U, Somesan V, Kadam S, Kohle S, Deshpande D, Shrivastava SK.

Brachytherapy. 2017 Jan - Feb;16(1):153-160. doi: 10.1016/j.brachy.2016.10.003. Epub 2016 Nov 19.


Nucleic Acid Delivery for Endothelial Dysfunction in Cardiovascular Diseases.

Deshpande D, Janero DR, Segura-Ibarra V, Blanco E, Amiji MM.

Methodist Debakey Cardiovasc J. 2016 Sep;12(3):134-140. Review.


Preclinical and Healthy Volunteer Studies of Potential Drug-Drug Interactions Between Tenapanor and Phosphate Binders.

Johansson S, Leonsson-Zachrisson M, Knutsson M, Spencer AG, Labonté ED, Deshpande D, Kohler J, Kozuka K, Charmot D, Rosenbaum DP.

Clin Pharmacol Drug Dev. 2017 Sep;6(5):448-456. doi: 10.1002/cpdd.307. Epub 2016 Oct 26.


Optimal Clinical Doses of Faropenem, Linezolid, and Moxifloxacin in Children With Disseminated Tuberculosis: Goldilocks.

Srivastava S, Deshpande D, Pasipanodya J, Nuermberger E, Swaminathan S, Gumbo T.

Clin Infect Dis. 2016 Nov 1;63(suppl 3):S102-S109.


A Faropenem, Linezolid, and Moxifloxacin Regimen for Both Drug-Susceptible and Multidrug-Resistant Tuberculosis in Children: FLAME Path on the Milky Way.

Deshpande D, Srivastava S, Nuermberger E, Pasipanodya JG, Swaminathan S, Gumbo T.

Clin Infect Dis. 2016 Nov 1;63(suppl 3):S95-S101.


Concentration-Dependent Synergy and Antagonism of Linezolid and Moxifloxacin in the Treatment of Childhood Tuberculosis: The Dynamic Duo.

Deshpande D, Srivastava S, Nuermberger E, Pasipanodya JG, Swaminathan S, Gumbo T.

Clin Infect Dis. 2016 Nov 1;63(suppl 3):S88-S94.


Linezolid for Infants and Toddlers With Disseminated Tuberculosis: First Steps.

Deshpande D, Srivastava S, Pasipanodya JG, Bush SJ, Nuermberger E, Swaminathan S, Gumbo T.

Clin Infect Dis. 2016 Nov 1;63(suppl 3):S80-S87.


A Combination Regimen Design Program Based on Pharmacodynamic Target Setting for Childhood Tuberculosis: Design Rules for the Playground.

Srivastava S, Deshpande D, Pasipanodya JG, Thomas T, Swaminathan S, Nuermberger E, Gumbo T.

Clin Infect Dis. 2016 Nov 1;63(suppl 3):S75-S79. Review.


Drug Concentration Thresholds Predictive of Therapy Failure and Death in Children With Tuberculosis: Bread Crumb Trails in Random Forests.

Swaminathan S, Pasipanodya JG, Ramachandran G, Hemanth Kumar AK, Srivastava S, Deshpande D, Nuermberger E, Gumbo T.

Clin Infect Dis. 2016 Nov 1;63(suppl 3):S63-S74.


Wheezing disorders in children: Are girls and boys different?

Deshpande D, Morgan W.

J Allergy Clin Immunol. 2016 Dec;138(6):1569-1570. doi: 10.1016/j.jaci.2016.07.034. Epub 2016 Sep 13. No abstract available.


Failure of the Amikacin, Cefoxitin, and Clarithromycin Combination Regimen for Treating Pulmonary Mycobacterium abscessus Infection.

Ferro BE, Srivastava S, Deshpande D, Pasipanodya JG, van Soolingen D, Mouton JW, van Ingen J, Gumbo T.

Antimicrob Agents Chemother. 2016 Sep 23;60(10):6374-6. doi: 10.1128/AAC.00990-16. Print 2016 Oct.


Amikacin Optimal Exposure Targets in the Hollow-Fiber System Model of Tuberculosis.

Srivastava S, Modongo C, Siyambalapitiyage Dona CW, Pasipanodya JG, Deshpande D, Gumbo T.

Antimicrob Agents Chemother. 2016 Sep 23;60(10):5922-7. doi: 10.1128/AAC.00961-16. Print 2016 Oct.


The effect of Nurse GraduaTeness on patient mortality: a cross-sectional survey (the NuGaT study).

Gkantaras I, Mahfoud ZR, Foreman B, Thompson DR, Cannaby AM, Deshpande DH, Watson R, Topping A, Gray R.

J Adv Nurs. 2016 Dec;72(12):3034-3044. doi: 10.1111/jan.13059. Epub 2016 Jul 27.


Thioridazine as Chemotherapy for Mycobacterium avium Complex Diseases.

Deshpande D, Srivastava S, Musuka S, Gumbo T.

Antimicrob Agents Chemother. 2016 Jul 22;60(8):4652-8. doi: 10.1128/AAC.02985-15. Print 2016 Aug.


A Long-term Co-perfused Disseminated Tuberculosis-3D Liver Hollow Fiber Model for Both Drug Efficacy and Hepatotoxicity in Babies.

Srivastava S, Pasipanodya JG, Ramachandran G, Deshpande D, Shuford S, Crosswell HE, Cirrincione KN, Sherman CM, Swaminathan S, Gumbo T.

EBioMedicine. 2016 Apr;6:126-138. doi: 10.1016/j.ebiom.2016.02.040. Epub 2016 Feb 27.


The dilemma of systemic steroids in preschool children with recurrent wheezing exacerbations.

Deshpande DR, Martinez FD.

Pediatr Pulmonol. 2016 Aug;51(8):775-7. doi: 10.1002/ppul.23465. Epub 2016 May 9. No abstract available.


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