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Items: 8


ASK1-P38 pathway is important for anoikis induced by microtubule-targeting aryl chloroethylureas.

Fortin J, Patenaude A, Deschesnes RG, Côté MF, Petitclerc E, C-Gaudreault R.

J Pharm Pharm Sci. 2010;13(2):175-90.


Analytical performance of a qRT-PCR assay to detect guanylyl cyclase C in FFPE lymph nodes of patients with colon cancer.

Beaulieu M, Desaulniers M, Bertrand N, Deschesnes RG, Beaudry G, Garon G, Haince JF, Houde M, Holzer TJ.

Diagn Mol Pathol. 2010 Mar;19(1):20-7. doi: 10.1097/PDM.0b013e3181ad5ac3.


New soft alkylating agents with enhanced cytotoxicity against cancer cells resistant to chemotherapeutics and hypoxia.

Patenaude A, Deschesnes RG, Rousseau JL, Petitclerc E, Lacroix J, Côté MF, C-Gaudreault R.

Cancer Res. 2007 Mar 1;67(5):2306-16.


Microtubule-destabilizing agents induce focal adhesion structure disorganization and anoikis in cancer cells.

Deschesnes RG, Patenaude A, Rousseau JL, Fortin JS, Ricard C, Côté MF, Huot J, C-Gaudreault R, Petitclerc E.

J Pharmacol Exp Ther. 2007 Feb;320(2):853-64. Epub 2006 Nov 10.


Antiangiogenic and antitumoral activity of phenyl-3-(2-chloroethyl)ureas: a class of soft alkylating agents disrupting microtubules that are unaffected by cell adhesion-mediated drug resistance.

Petitclerc E, Deschesnes RG, Côté MF, Marquis C, Janvier R, Lacroix J, Miot-Noirault E, Legault J, Mounetou E, Madelmont JC, C -Gaudreault R.

Cancer Res. 2004 Jul 1;64(13):4654-63.


c-Myc potentiates the mitochondrial pathway of apoptosis by acting upstream of apoptosis signal-regulating kinase 1 (Ask1) in the p38 signalling cascade.

Desbiens KM, Deschesnes RG, Labrie MM, Desfossés Y, Lambert H, Landry J, Bellmann K.

Biochem J. 2003 Jun 1;372(Pt 2):631-41.


Involvement of p38 in apoptosis-associated membrane blebbing and nuclear condensation.

Deschesnes RG, Huot J, Valerie K, Landry J.

Mol Biol Cell. 2001 Jun;12(6):1569-82.


SAPK2/p38-dependent F-actin reorganization regulates early membrane blebbing during stress-induced apoptosis.

Huot J, Houle F, Rousseau S, Deschesnes RG, Shah GM, Landry J.

J Cell Biol. 1998 Nov 30;143(5):1361-73.

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