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Items: 1 to 50 of 635

1.

Synthesis and Characterization of the Selective, Reversible PKCβ Inhibitor (9 S)-9-[(Dimethylamino)methyl]-6,7,10,11-tetrahydro-9 H,18 H-5,21:12,17-dimethenodibenzo[ e,k]pyrrolo[3,4- h][1,4,13]oxadiazacyclohexadecine-18,20(19 H)-dione, Ruboxistaurin (LY333531).

Lewin AH, Brieaddy L, Deschamps JR, Imler GH, Mascarella SW, Reddy PA, Carroll FI.

ACS Chem Neurosci. 2018 Sep 11. doi: 10.1021/acschemneuro.8b00196. [Epub ahead of print]

PMID:
30156829
2.

Systematic Nanoscale Analysis of Endocytosis Links Efficient Vesicle Formation to Patterned Actin Nucleation.

Mund M, van der Beek JA, Deschamps J, Dmitrieff S, Hoess P, Monster JL, Picco A, Nédélec F, Kaksonen M, Ries J.

Cell. 2018 Aug 9;174(4):884-896.e17. doi: 10.1016/j.cell.2018.06.032. Epub 2018 Jul 26.

3.

Vascular Delivery of Allogeneic MuStem Cells in Dystrophic Dogs Requires Only Short-Term Immunosuppression to Avoid Host Immunity and Generate Clinical/Tissue Benefits.

Lorant J, Larcher T, Jaulin N, Hedan B, Lardenois A, Leroux I, Dubreil L, Ledevin M, Goubin H, Moullec S, Deschamps JY, Thorin C, André C, Adjali O, Rouger K.

Cell Transplant. 2018 Jul;27(7):1096-1110. doi: 10.1177/0963689718776306. Epub 2018 Jun 5.

PMID:
29871519
4.

Two CuII complexes of 3,4,5-tri-methyl-1H-pyrazole.

Vincent CJ, Giles ID, Deschamps JR.

Acta Crystallogr E Crystallogr Commun. 2018 Feb 16;74(Pt 3):357-362. doi: 10.1107/S2056989018002359. eCollection 2018 Mar 1.

5.

A High Aspect Ratio Bifurcated 128-Microchannel Microfluidic Device for Environmental Monitoring of Explosives.

Charles PT, Wadhwa V, Kouyate A, Mesa-Donado KJ, Adams AA, Deschamps JR, Kusterbeck AW.

Sensors (Basel). 2018 May 15;18(5). pii: E1568. doi: 10.3390/s18051568.

6.

Synthesis and Structural Elucidation of a Pyranomorphinan Opioid and in Vitro Studies.

Ansari MI, Healy JR, Hom K, Deschamps JR, Matsumoto RR, Coop A.

Org Lett. 2018 May 18;20(10):2984-2987. doi: 10.1021/acs.orglett.8b01025. Epub 2018 May 8.

PMID:
29737176
7.

Complete genome sequence of Bacillus velezensis QST713: A biocontrol agent that protects Agaricus bisporus crops against the green mould disease.

Pandin C, Le Coq D, Deschamps J, Védie R, Rousseau T, Aymerich S, Briandet R.

J Biotechnol. 2018 Jul 20;278:10-19. doi: 10.1016/j.jbiotec.2018.04.014. Epub 2018 Apr 24.

PMID:
29702132
8.

Impact of modified diamond-like carbon coatings on the spatial organization and disinfection of mixed-biofilms composed of Escherichia coli and Pantoea agglomerans industrial isolates.

Gomes LC, Deschamps J, Briandet R, Mergulhão FJ.

Int J Food Microbiol. 2018 Jul 20;277:74-82. doi: 10.1016/j.ijfoodmicro.2018.04.017. Epub 2018 Apr 12.

PMID:
29689455
9.

Reaction Kinetics Direct a Rational Synthesis of an HIV-1 Inactivator of Nucleocapsid Protein 7 and Provide Mechanistic Insight into Cellular Metabolism and Antiviral Activity.

Nikolayevskiy H, Scerba MT, Deschamps JR, Appella DH.

Chemistry. 2018 Jul 5;24(38):9485-9489. doi: 10.1002/chem.201801253. Epub 2018 May 25.

PMID:
29653024
10.

Real-time 3D single-molecule localization using experimental point spread functions.

Li Y, Mund M, Hoess P, Deschamps J, Matti U, Nijmeijer B, Sabinina VJ, Ellenberg J, Schoen I, Ries J.

Nat Methods. 2018 May;15(5):367-369. doi: 10.1038/nmeth.4661. Epub 2018 Apr 9.

PMID:
29630062
11.

Engineering Immunological Tolerance Using Quantum Dots to Tune the Density of Self-Antigen Display.

Hess KL, Oh E, Tostanoski LH, Andorko JI, Susumu K, Deschamps JR, Medintz IL, Jewell CM.

Adv Funct Mater. 2017 Jun 13;27(22). pii: 1700290. doi: 10.1002/adfm.201700290. Epub 2017 Apr 3.

12.

The Cdx2 homeobox gene suppresses intestinal tumorigenesis through non-cell-autonomous mechanisms.

Balbinot C, Armant O, Elarouci N, Marisa L, Martin E, De Clara E, Onea A, Deschamps J, Beck F, Freund JN, Duluc I.

J Exp Med. 2018 Mar 5;215(3):911-926. doi: 10.1084/jem.20170934. Epub 2018 Feb 8.

13.

Exploration of the role of the virulence factor ElrA during Enterococcus faecalis cell infection.

Nunez N, Derré-Bobillot A, Gaubert S, Herry JM, Deschamps J, Wei Y, Baranek T, Si-Tahar M, Briandet R, Serror P, Archambaud C.

Sci Rep. 2018 Jan 29;8(1):1749. doi: 10.1038/s41598-018-20206-6.

14.

Impact of Cell Surface Molecules on Conjugative Transfer of the Integrative and Conjugative Element ICESt3 of Streptococcus thermophilus.

Dahmane N, Robert E, Deschamps J, Meylheuc T, Delorme C, Briandet R, Leblond-Bourget N, Guédon E, Payot S.

Appl Environ Microbiol. 2018 Feb 14;84(5). pii: e02109-17. doi: 10.1128/AEM.02109-17. Print 2018 Mar 1.

15.

Total Synthesis of Sarpagine-Related Bioactive Indole Alkaloids.

Rahman MT, Deschamps JR, Imler GH, Cook JM.

Chemistry. 2018 Feb 16;24(10):2354-2359. doi: 10.1002/chem.201705575. Epub 2018 Jan 23.

PMID:
29244896
16.

A Stable Heroin Analogue That Can Serve as a Vaccine Hapten to Induce Antibodies That Block the Effects of Heroin and Its Metabolites in Rodents and That Cross-React Immunologically with Related Drugs of Abuse.

Sulima A, Jalah R, Antoline JFG, Torres OB, Imler GH, Deschamps JR, Beck Z, Alving CR, Jacobson AE, Rice KC, Matyas GR.

J Med Chem. 2018 Jan 11;61(1):329-343. doi: 10.1021/acs.jmedchem.7b01427. Epub 2017 Dec 29.

17.

Concise Total Synthesis of (-)-Affinisine Oxindole, (+)-Isoalstonisine, (+)-Alstofoline, (-)-Macrogentine, (+)-Na -Demethylalstonisine, (-)-Alstonoxine A, and (+)-Alstonisine.

Stephen MR, Rahman MT, Tiruveedhula VVNPB, Fonseca GO, Deschamps JR, Cook JM.

Chemistry. 2017 Nov 7;23(62):15805-15819. doi: 10.1002/chem.201703572. Epub 2017 Oct 18.

PMID:
28875520
18.

Fine-tuning and autoregulation of the intestinal determinant and tumor suppressor homeobox gene CDX2 by alternative splicing.

Balbinot C, Vanier M, Armant O, Nair A, Penichon J, Soret C, Martin E, Saandi T, Reimund JM, Deschamps J, Beck F, Domon-Dell C, Gross I, Duluc I, Freund JN.

Cell Death Differ. 2017 Dec;24(12):2173-2186. doi: 10.1038/cdd.2017.140. Epub 2017 Sep 1.

PMID:
28862703
19.

Embryonic timing, axial stem cells, chromatin dynamics, and the Hox clock.

Deschamps J, Duboule D.

Genes Dev. 2017 Jul 15;31(14):1406-1416. doi: 10.1101/gad.303123.117. Review.

20.

Crystal structures of the three closely related compounds: bis-[(1H-tetra-zol-5-yl)meth-yl]nitramide, tri-amino-guanidinium 5-({[(1H-tetra-zol-5-yl)meth-yl](nitro)-amino}-meth-yl)tetra-zol-1-ide, and di-ammonium bis-[(tetra-zol-1-id-5-yl)meth-yl]nitramide monohydrate.

Mitchell LA, Imler GH, Parrish DA, Deschamps JR, Leonard PW, Chavez DE.

Acta Crystallogr E Crystallogr Commun. 2017 Jun 20;73(Pt 7):1056-1061. doi: 10.1107/S2056989017008817. eCollection 2017 Jul 1.

21.

Long-term microdystrophin gene therapy is effective in a canine model of Duchenne muscular dystrophy.

Le Guiner C, Servais L, Montus M, Larcher T, Fraysse B, Moullec S, Allais M, François V, Dutilleul M, Malerba A, Koo T, Thibaut JL, Matot B, Devaux M, Le Duff J, Deschamps JY, Barthelemy I, Blot S, Testault I, Wahbi K, Ederhy S, Martin S, Veron P, Georger C, Athanasopoulos T, Masurier C, Mingozzi F, Carlier P, Gjata B, Hogrel JY, Adjali O, Mavilio F, Voit T, Moullier P, Dickson G.

Nat Commun. 2017 Jul 25;8:16105. doi: 10.1038/ncomms16105.

22.

At the base of colinear Hox gene expression: cis-features and trans-factors orchestrating the initial phase of Hox cluster activation.

Neijts R, Deschamps J.

Dev Biol. 2017 Aug 15;428(2):293-299. doi: 10.1016/j.ydbio.2017.02.009. Review.

23.

Nanoparticle cellular uptake by dendritic wedge peptides: achieving single peptide facilitated delivery.

Breger JC, Muttenthaler M, Delehanty JB, Thompson DA, Oh E, Susumu K, Deschamps JR, Anderson GP, Field LD, Walper SA, Dawson PE, Medintz IL.

Nanoscale. 2017 Jul 27;9(29):10447-10464. doi: 10.1039/c7nr03362a.

PMID:
28703833
24.

Elucidating Surface Ligand-Dependent Kinetic Enhancement of Proteolytic Activity at Surface-Modified Quantum Dots.

Díaz SA, Sen S, Boeneman Gemmill K, Brown CW 3rd, Oh E, Susumu K, Stewart MH, Breger JC, Lasarte Aragonés G, Field LD, Deschamps JR, Král P, Medintz IL.

ACS Nano. 2017 Jun 27;11(6):5884-5896. doi: 10.1021/acsnano.7b01624. Epub 2017 Jun 12.

PMID:
28603969
25.

Quantum Dot-Peptide-Fullerene Bioconjugates for Visualization of in Vitro and in Vivo Cellular Membrane Potential.

Nag OK, Stewart MH, Deschamps JR, Susumu K, Oh E, Tsytsarev V, Tang Q, Efros AL, Vaxenburg R, Black BJ, Chen Y, O'Shaughnessy TJ, North SH, Field LD, Dawson PE, Pancrazio JJ, Medintz IL, Chen Y, Erzurumlu RS, Huston AL, Delehanty JB.

ACS Nano. 2017 Jun 27;11(6):5598-5613. doi: 10.1021/acsnano.7b00954. Epub 2017 May 30.

26.

One-pot sequential reaction to 2-substituted-phenanthridinones from N-methoxybenzamides.

Liang D, Sersen D, Yang C, Deschamps JR, Imler GH, Jiang C, Xue F.

Org Biomol Chem. 2017 May 23;15(20):4390-4398. doi: 10.1039/c7ob00649g.

PMID:
28475192
27.

Modulation of opioid receptor affinity and efficacy via N-substitution of 9β-hydroxy-5-(3-hydroxyphenyl)morphan: Synthesis and computer simulation study.

Truong PM, Hassan SA, Lee YS, Kopajtic TA, Katz JL, Chadderdon AM, Traynor JR, Deschamps JR, Jacobson AE, Rice KC.

Bioorg Med Chem. 2017 Apr 15;25(8):2406-2422. doi: 10.1016/j.bmc.2017.02.064. Epub 2017 Mar 1.

28.

Iodobenzene-Catalyzed Synthesis of Phenanthridinones via Oxidative C-H Amidation.

Liang D, Yu W, Nguyen N, Deschamps JR, Imler GH, Li Y, MacKerell AD Jr, Jiang C, Xue F.

J Org Chem. 2017 Apr 7;82(7):3589-3596. doi: 10.1021/acs.joc.7b00106. Epub 2017 Mar 10.

PMID:
28245353
29.

Comparison of biofilm formation and motility processes in arsenic-resistant Thiomonas spp. strains revealed divergent response to arsenite.

Farasin J, Koechler S, Varet H, Deschamps J, Dillies MA, Proux C, Erhardt M, Huber A, Jagla B, Briandet R, Coppée JY, Arsène-Ploetze F.

Microb Biotechnol. 2017 Jul;10(4):789-803. doi: 10.1111/1751-7915.12556. Epub 2017 Feb 7.

30.

Charte d’Ottawa : traduction ou trahison ?

Ferron C, Deschamps JP.

Sante Publique. 2016 Dec 19;28(6):715-716. French. No abstract available.

PMID:
28155762
31.

La Charte d’Ottawa a trente ans...

Deschamps JP.

Sante Publique. 2016 Dec 19;28(6):711. French. No abstract available.

PMID:
28155760
32.

Enantiospecific Allosteric Modulation of Cannabinoid 1 Receptor.

Laprairie RB, Kulkarni PM, Deschamps JR, Kelly MEM, Janero DR, Cascio MG, Stevenson LA, Pertwee RG, Kenakin TP, Denovan-Wright EM, Thakur GA.

ACS Chem Neurosci. 2017 Jun 21;8(6):1188-1203. doi: 10.1021/acschemneuro.6b00310. Epub 2017 Feb 7.

PMID:
28103441
33.

Cdx is crucial for the timing mechanism driving colinear Hox activation and defines a trunk segment in the Hox cluster topology.

Neijts R, Amin S, van Rooijen C, Deschamps J.

Dev Biol. 2017 Feb 15;422(2):146-154. doi: 10.1016/j.ydbio.2016.12.024. Epub 2016 Dec 29.

34.

Cdx and T Brachyury Co-activate Growth Signaling in the Embryonic Axial Progenitor Niche.

Amin S, Neijts R, Simmini S, van Rooijen C, Tan SC, Kester L, van Oudenaarden A, Creyghton MP, Deschamps J.

Cell Rep. 2016 Dec 20;17(12):3165-3177. doi: 10.1016/j.celrep.2016.11.069.

35.

Toward Understanding the Structural Basis of Partial Agonism at the Dopamine D3 Receptor.

Michino M, Boateng CA, Donthamsetti P, Yano H, Bakare OM, Bonifazi A, Ellenberger MP, Keck TM, Kumar V, Zhu C, Verma R, Deschamps JR, Javitch JA, Newman AH, Shi L.

J Med Chem. 2017 Jan 26;60(2):580-593. doi: 10.1021/acs.jmedchem.6b01148. Epub 2017 Jan 5.

36.

Efficient homogeneous illumination and optical sectioning for quantitative single-molecule localization microscopy.

Deschamps J, Rowald A, Ries J.

Opt Express. 2016 Nov 28;24(24):28080-28090. doi: 10.1364/OE.24.028080.

PMID:
27906373
37.

Design, Synthesis, and Biological Evaluation of Structurally Rigid Analogues of 4-(3-Hydroxyphenyl)piperidine Opioid Receptor Antagonists.

Runyon SP, Kormos CM, Gichinga MG, Mascarella SW, Navarro HA, Deschamps JR, Imler GH, Carroll FI.

J Org Chem. 2016 Nov 4;81(21):10383-10391. Epub 2016 Aug 2.

38.

On the shoulders of Hubrecht: From embryos to stem cells.

Rabouille C, Deschamps J.

Dev Biol. 2017 Aug 15;428(2):264-272. doi: 10.1016/j.ydbio.2016.10.005. Epub 2016 Oct 17. Review.

39.

Human 15-LOX-1 active site mutations alter inhibitor binding and decrease potency.

Armstrong M, van Hoorebeke C, Horn T, Deschamps J, Freedman JC, Kalyanaraman C, Jacobson MP, Holman T.

Bioorg Med Chem. 2016 Nov 1;24(21):5380-5387. doi: 10.1016/j.bmc.2016.08.063. Epub 2016 Aug 31.

40.

Polarized regulatory landscape and Wnt responsiveness underlie Hox activation in embryos.

Neijts R, Amin S, van Rooijen C, Tan S, Creyghton MP, de Laat W, Deschamps J.

Genes Dev. 2016 Sep 1;30(17):1937-42. doi: 10.1101/gad.285767.116. Epub 2016 Sep 15.

41.

Cyclotriveratrylene-Containing Porphyrins.

Deschamps J, Langlois A, Martin G, Bucher L, Desbois N, Gros CP, Harvey PD.

Inorg Chem. 2016 Sep 19;55(18):9230-9. doi: 10.1021/acs.inorgchem.6b01261. Epub 2016 Sep 7.

PMID:
27603751
42.

Total Synthesis of Macrocarpines D and E via an Enolate-Driven Copper-Mediated Cross-Coupling Process: Replacement of Catalytic Palladium with Copper Iodide.

Rahman MT, Deschamps JR, Imler GH, Schwabacher AW, Cook JM.

Org Lett. 2016 Sep 2;18(17):4174-7. doi: 10.1021/acs.orglett.6b01526. Epub 2016 Aug 16.

43.

Discovery of a novel small molecule agonist scaffold for the APJ receptor.

Narayanan S, Maitra R, Deschamps JR, Bortoff K, Thomas JB, Zhang Y, Warner K, Vasukuttan V, Decker A, Runyon SP.

Bioorg Med Chem. 2016 Aug 15;24(16):3758-70. doi: 10.1016/j.bmc.2016.06.018. Epub 2016 Jun 11.

44.

Hydrosol of Thymbra capitata Is a Highly Efficient Biocide against Salmonella enterica Serovar Typhimurium Biofilms.

Karampoula F, Giaouris E, Deschamps J, Doulgeraki AI, Nychas GJ, Dubois-Brissonnet F.

Appl Environ Microbiol. 2016 Aug 15;82(17):5309-19. doi: 10.1128/AEM.01351-16. Print 2016 Sep 1.

45.

Effects of Two Types of Melatonin-Loaded Nanocapsules with Distinct Supramolecular Structures: Polymeric (NC) and Lipid-Core Nanocapsules (LNC) on Bovine Embryo Culture Model.

Komninou ER, Remião MH, Lucas CG, Domingues WB, Basso AC, Jornada DS, Deschamps JC, Beck RC, Pohlmann AR, Bordignon V, Seixas FK, Campos VF, Guterres SS, Collares T.

PLoS One. 2016 Jun 16;11(6):e0157561. doi: 10.1371/journal.pone.0157561. eCollection 2016.

46.

Vitrectomy Before Intravitreal Injection of AAV2/2 Vector Promotes Efficient Transduction of Retinal Ganglion Cells in Dogs and Nonhuman Primates.

Tshilenge KT, Ameline B, Weber M, Mendes-Madeira A, Nedellec S, Biget M, Provost N, Libeau L, Blouin V, Deschamps JY, Le Meur G, Colle MA, Moullier P, Pichard V, Rolling F.

Hum Gene Ther Methods. 2016 Jun;27(3):122-34. doi: 10.1089/hgtb.2016.034.

PMID:
27229628
47.

Biochemical and Cellular Characterization and Inhibitor Discovery of Pseudomonas aeruginosa 15-Lipoxygenase.

Deschamps JD, Ogunsola AF, Jameson JB 2nd, Yasgar A, Flitter BA, Freedman CJ, Melvin JA, Nguyen JV, Maloney DJ, Jadhav A, Simeonov A, Bomberger JM, Holman TR.

Biochemistry. 2016 Jun 14;55(23):3329-40. doi: 10.1021/acs.biochem.6b00338. Epub 2016 Jun 3.

PMID:
27226387
48.

Birth and upgrowth of the Hox topological domains during evolution.

Deschamps J.

Nat Genet. 2016 Mar;48(3):227-8. doi: 10.1038/ng.3514.

PMID:
26906681
49.

AAV-mediated Gene Therapy Halts Retinal Degeneration in PDE6β-deficient Dogs.

Pichard V, Provost N, Mendes-Madeira A, Libeau L, Hulin P, Tshilenge KT, Biget M, Ameline B, Deschamps JY, Weber M, Le Meur G, Colle MA, Moullier P, Rolling F.

Mol Ther. 2016 May;24(5):867-76. doi: 10.1038/mt.2016.37. Epub 2016 Feb 9.

50.

Refractory hypoglycaemia in a dog infected with Trypanosoma congolense.

Deschamps JY, Desquesnes M, Dorso L, Ravel S, Bossard G, Charbonneau M, Garand A, Roux FA.

Parasite. 2016;23:1. doi: 10.1051/parasite/2016001. Epub 2016 Jan 21.

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