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Items: 1 to 50 of 649

1.

C4-Phenylthio β-lactams: Effect of the chirality of the β-lactam ring on antimicrobial activity.

Kuskovsky R, Lloyd D, Arora K, Plotkin BJ, Green JM, Boshoff HI, Barry C 3rd, Deschamps J, Konaklieva MI.

Bioorg Med Chem. 2019 Aug 20:115050. doi: 10.1016/j.bmc.2019.115050. [Epub ahead of print]

PMID:
31474471
2.

A Novel Bromine-Containing Paroxetine Analogue Provides Mechanistic Clues for Binding Ambiguity at the Central Primary Binding Site of the Serotonin Transporter.

Slack RD, Abramyan AM, Tang H, Meena S, Davis BA, Bonifazi A, Giancola JB, Deschamps JR, Naing S, Yano H, Singh SK, Newman AH, Shi L.

ACS Chem Neurosci. 2019 Aug 22. doi: 10.1021/acschemneuro.9b00375. [Epub ahead of print]

PMID:
31424193
3.

Two FtsH Proteases Contribute to Fitness and Adaptation of Pseudomonas aeruginosa Clone C Strains.

Kamal SM, Rybtke ML, Nimtz M, Sperlein S, Giske C, Trček J, Deschamps J, Briandet R, Dini L, Jänsch L, Tolker-Nielsen T, Lee C, Römling U.

Front Microbiol. 2019 Jul 9;10:1372. doi: 10.3389/fmicb.2019.01372. eCollection 2019.

4.

The Significance of Chirality in Drug Design and Synthesis of Bitopic Ligands as D3 Receptor (D3R) Selective Agonists.

Battiti FO, Cemaj SL, Guerrero AM, Shaik AB, Lam J, Rais R, Slusher BS, Deschamps JR, Imler GH, Newman AH, Bonifazi A.

J Med Chem. 2019 Jul 11;62(13):6287-6314. doi: 10.1021/acs.jmedchem.9b00702. Epub 2019 Jul 1.

PMID:
31257877
5.

The Mutation of Conservative Asp268 Residue in the Peptidoglycan-Associated Domain of the OmpA Protein Affects Multiple Acinetobacter baumannii Virulence Characteristics.

Skerniškytė J, Karazijaitė E, Deschamps J, Krasauskas R, Briandet R, Sužiedėlienė E.

Molecules. 2019 May 22;24(10). pii: E1972. doi: 10.3390/molecules24101972.

6.

A microbiota-generated bile salt induces biofilm formation in Clostridium difficile.

Dubois T, Tremblay YDN, Hamiot A, Martin-Verstraete I, Deschamps J, Monot M, Briandet R, Dupuy B.

NPJ Biofilms Microbiomes. 2019 May 9;5:14. doi: 10.1038/s41522-019-0087-4. eCollection 2019.

7.

Association between harm reduction strategies and healthcare utilization in patients on long-term prescribed opioid therapy presenting to acute healthcare settings: a protocol for a systematic review and meta-analysis.

Deschamps J, Gilbertson J, Straube S, Dong K, MacMaster FP, Korownyk C, Montgomery L, Mahaffey R, Downar J, Clarke H, Muscedere J, Rittenbach K, Featherstone R, Sebastianski M, Vandermeer B, Lynam D, Magnussen R, Bagshaw SM, Rewa OG.

Syst Rev. 2019 Apr 5;8(1):88. doi: 10.1186/s13643-019-0997-5.

8.

Brain natriuretic peptide to predict successful liberation from mechanical ventilation in critically ill patients: protocol for a systematic review and meta-analysis.

Deschamps J, Webber J, Featherstone R, Sebastianski M, Vandermeer B, Senaratne J, Bagshaw SM.

BMJ Open. 2019 Feb 12;9(2):e022600. doi: 10.1136/bmjopen-2018-022600.

9.

High Content Screening Confocal Laser Microscopy (HCS-CLM) to Characterize Biofilm 4D Structural Dynamic of Foodborne Pathogens.

Canette A, Deschamps J, Briandet R.

Methods Mol Biol. 2019;1918:171-182. doi: 10.1007/978-1-4939-9000-9_14.

PMID:
30580408
10.

Probing the Electrostatic and Steric Requirements for Substrate Binding in Human Platelet-Type 12-Lipoxygenase.

Aleem AM, Tsai WC, Tena J, Alvarez G, Deschamps J, Kalyanaraman C, Jacobson MP, Holman T.

Biochemistry. 2019 Feb 12;58(6):848-857. doi: 10.1021/acs.biochem.8b01167. Epub 2019 Jan 4.

PMID:
30565457
11.

Conformational Details of Quantum Dot-DNA Resolved by Förster Resonance Energy Transfer Lifetime Nanoruler.

Guo J, Qiu X, Mingoes C, Deschamps JR, Susumu K, Medintz IL, Hildebrandt N.

ACS Nano. 2019 Jan 22;13(1):505-514. doi: 10.1021/acsnano.8b07137. Epub 2018 Dec 6.

PMID:
30508369
12.

B-973, a Novel α7 nAChR Ago-PAM: Racemic and Asymmetric Synthesis, Electrophysiological Studies, and in Vivo Evaluation.

Garai S, Raja KS, Papke RL, Deschamps JR, Damaj MI, Thakur GA.

ACS Med Chem Lett. 2018 Oct 11;9(11):1144-1148. doi: 10.1021/acsmedchemlett.8b00407. eCollection 2018 Nov 8.

PMID:
30429960
13.

Whole-head recording of chemosensory activity in the marine annelid Platynereis dumerilii.

Chartier TF, Deschamps J, Dürichen W, Jékely G, Arendt D.

Open Biol. 2018 Oct 31;8(10). pii: 180139. doi: 10.1098/rsob.180139.

14.

A handheld platform for target protein detection and quantification using disposable nanopore strips.

Morin TJ, McKenna WL, Shropshire TD, Wride DA, Deschamps JD, Liu X, Stamm R, Wang H, Dunbar WB.

Sci Rep. 2018 Oct 4;8(1):14834. doi: 10.1038/s41598-018-33086-7.

15.

Synthesis and Characterization of the Selective, Reversible PKCβ Inhibitor (9 S)-9-[(Dimethylamino)methyl]-6,7,10,11-tetrahydro-9 H,18 H-5,21:12,17-dimethenodibenzo[ e,k]pyrrolo[3,4- h][1,4,13]oxadiazacyclohexadecine-18,20(19 H)-dione, Ruboxistaurin (LY333531).

Lewin AH, Brieaddy L, Deschamps JR, Imler GH, Mascarella SW, Reddy PA, Carroll FI.

ACS Chem Neurosci. 2019 Jan 16;10(1):246-251. doi: 10.1021/acschemneuro.8b00196. Epub 2018 Sep 11.

PMID:
30156829
16.

Systematic Nanoscale Analysis of Endocytosis Links Efficient Vesicle Formation to Patterned Actin Nucleation.

Mund M, van der Beek JA, Deschamps J, Dmitrieff S, Hoess P, Monster JL, Picco A, Nédélec F, Kaksonen M, Ries J.

Cell. 2018 Aug 9;174(4):884-896.e17. doi: 10.1016/j.cell.2018.06.032. Epub 2018 Jul 26.

17.

Vascular Delivery of Allogeneic MuStem Cells in Dystrophic Dogs Requires Only Short-Term Immunosuppression to Avoid Host Immunity and Generate Clinical/Tissue Benefits.

Lorant J, Larcher T, Jaulin N, Hedan B, Lardenois A, Leroux I, Dubreil L, Ledevin M, Goubin H, Moullec S, Deschamps JY, Thorin C, André C, Adjali O, Rouger K.

Cell Transplant. 2018 Jul;27(7):1096-1110. doi: 10.1177/0963689718776306. Epub 2018 Jun 5.

18.

Two CuII complexes of 3,4,5-tri-methyl-1H-pyrazole.

Vincent CJ, Giles ID, Deschamps JR.

Acta Crystallogr E Crystallogr Commun. 2018 Feb 16;74(Pt 3):357-362. doi: 10.1107/S2056989018002359. eCollection 2018 Mar 1.

19.

A High Aspect Ratio Bifurcated 128-Microchannel Microfluidic Device for Environmental Monitoring of Explosives.

Charles PT, Wadhwa V, Kouyate A, Mesa-Donado KJ, Adams AA, Deschamps JR, Kusterbeck AW.

Sensors (Basel). 2018 May 15;18(5). pii: E1568. doi: 10.3390/s18051568.

20.

Synthesis and Structural Elucidation of a Pyranomorphinan Opioid and in Vitro Studies.

Ansari MI, Healy JR, Hom K, Deschamps JR, Matsumoto RR, Coop A.

Org Lett. 2018 May 18;20(10):2984-2987. doi: 10.1021/acs.orglett.8b01025. Epub 2018 May 8.

PMID:
29737176
21.

Complete genome sequence of Bacillus velezensis QST713: A biocontrol agent that protects Agaricus bisporus crops against the green mould disease.

Pandin C, Le Coq D, Deschamps J, Védie R, Rousseau T, Aymerich S, Briandet R.

J Biotechnol. 2018 Jul 20;278:10-19. doi: 10.1016/j.jbiotec.2018.04.014. Epub 2018 Apr 24.

PMID:
29702132
22.

Impact of modified diamond-like carbon coatings on the spatial organization and disinfection of mixed-biofilms composed of Escherichia coli and Pantoea agglomerans industrial isolates.

Gomes LC, Deschamps J, Briandet R, Mergulhão FJ.

Int J Food Microbiol. 2018 Jul 20;277:74-82. doi: 10.1016/j.ijfoodmicro.2018.04.017. Epub 2018 Apr 12.

PMID:
29689455
23.

Reaction Kinetics Direct a Rational Synthesis of an HIV-1 Inactivator of Nucleocapsid Protein 7 and Provide Mechanistic Insight into Cellular Metabolism and Antiviral Activity.

Nikolayevskiy H, Scerba MT, Deschamps JR, Appella DH.

Chemistry. 2018 Jul 5;24(38):9485-9489. doi: 10.1002/chem.201801253. Epub 2018 May 25.

PMID:
29653024
24.

Real-time 3D single-molecule localization using experimental point spread functions.

Li Y, Mund M, Hoess P, Deschamps J, Matti U, Nijmeijer B, Sabinina VJ, Ellenberg J, Schoen I, Ries J.

Nat Methods. 2018 May;15(5):367-369. doi: 10.1038/nmeth.4661. Epub 2018 Apr 9.

25.

Engineering Immunological Tolerance Using Quantum Dots to Tune the Density of Self-Antigen Display.

Hess KL, Oh E, Tostanoski LH, Andorko JI, Susumu K, Deschamps JR, Medintz IL, Jewell CM.

Adv Funct Mater. 2017 Jun 13;27(22). pii: 1700290. doi: 10.1002/adfm.201700290. Epub 2017 Apr 3.

26.

The Cdx2 homeobox gene suppresses intestinal tumorigenesis through non-cell-autonomous mechanisms.

Balbinot C, Armant O, Elarouci N, Marisa L, Martin E, De Clara E, Onea A, Deschamps J, Beck F, Freund JN, Duluc I.

J Exp Med. 2018 Mar 5;215(3):911-926. doi: 10.1084/jem.20170934. Epub 2018 Feb 8.

27.

Exploration of the role of the virulence factor ElrA during Enterococcus faecalis cell infection.

Nunez N, Derré-Bobillot A, Gaubert S, Herry JM, Deschamps J, Wei Y, Baranek T, Si-Tahar M, Briandet R, Serror P, Archambaud C.

Sci Rep. 2018 Jan 29;8(1):1749. doi: 10.1038/s41598-018-20206-6.

28.

Impact of Cell Surface Molecules on Conjugative Transfer of the Integrative and Conjugative Element ICESt3 of Streptococcus thermophilus.

Dahmane N, Robert E, Deschamps J, Meylheuc T, Delorme C, Briandet R, Leblond-Bourget N, Guédon E, Payot S.

Appl Environ Microbiol. 2018 Feb 14;84(5). pii: e02109-17. doi: 10.1128/AEM.02109-17. Print 2018 Mar 1.

29.

Total Synthesis of Sarpagine-Related Bioactive Indole Alkaloids.

Rahman MT, Deschamps JR, Imler GH, Cook JM.

Chemistry. 2018 Feb 16;24(10):2354-2359. doi: 10.1002/chem.201705575. Epub 2018 Jan 23.

PMID:
29244896
30.

A Stable Heroin Analogue That Can Serve as a Vaccine Hapten to Induce Antibodies That Block the Effects of Heroin and Its Metabolites in Rodents and That Cross-React Immunologically with Related Drugs of Abuse.

Sulima A, Jalah R, Antoline JFG, Torres OB, Imler GH, Deschamps JR, Beck Z, Alving CR, Jacobson AE, Rice KC, Matyas GR.

J Med Chem. 2018 Jan 11;61(1):329-343. doi: 10.1021/acs.jmedchem.7b01427. Epub 2017 Dec 29.

31.

Concise Total Synthesis of (-)-Affinisine Oxindole, (+)-Isoalstonisine, (+)-Alstofoline, (-)-Macrogentine, (+)-Na -Demethylalstonisine, (-)-Alstonoxine A, and (+)-Alstonisine.

Stephen MR, Rahman MT, Tiruveedhula VVNPB, Fonseca GO, Deschamps JR, Cook JM.

Chemistry. 2017 Nov 7;23(62):15805-15819. doi: 10.1002/chem.201703572. Epub 2017 Oct 18.

32.

Fine-tuning and autoregulation of the intestinal determinant and tumor suppressor homeobox gene CDX2 by alternative splicing.

Balbinot C, Vanier M, Armant O, Nair A, Penichon J, Soret C, Martin E, Saandi T, Reimund JM, Deschamps J, Beck F, Domon-Dell C, Gross I, Duluc I, Freund JN.

Cell Death Differ. 2017 Dec;24(12):2173-2186. doi: 10.1038/cdd.2017.140. Epub 2017 Sep 1.

33.

Embryonic timing, axial stem cells, chromatin dynamics, and the Hox clock.

Deschamps J, Duboule D.

Genes Dev. 2017 Jul 15;31(14):1406-1416. doi: 10.1101/gad.303123.117. Review.

34.

Crystal structures of the three closely related compounds: bis-[(1H-tetra-zol-5-yl)meth-yl]nitramide, tri-amino-guanidinium 5-({[(1H-tetra-zol-5-yl)meth-yl](nitro)-amino}-meth-yl)tetra-zol-1-ide, and di-ammonium bis-[(tetra-zol-1-id-5-yl)meth-yl]nitramide monohydrate.

Mitchell LA, Imler GH, Parrish DA, Deschamps JR, Leonard PW, Chavez DE.

Acta Crystallogr E Crystallogr Commun. 2017 Jun 20;73(Pt 7):1056-1061. doi: 10.1107/S2056989017008817. eCollection 2017 Jul 1.

35.

Long-term microdystrophin gene therapy is effective in a canine model of Duchenne muscular dystrophy.

Le Guiner C, Servais L, Montus M, Larcher T, Fraysse B, Moullec S, Allais M, François V, Dutilleul M, Malerba A, Koo T, Thibaut JL, Matot B, Devaux M, Le Duff J, Deschamps JY, Barthelemy I, Blot S, Testault I, Wahbi K, Ederhy S, Martin S, Veron P, Georger C, Athanasopoulos T, Masurier C, Mingozzi F, Carlier P, Gjata B, Hogrel JY, Adjali O, Mavilio F, Voit T, Moullier P, Dickson G.

Nat Commun. 2017 Jul 25;8:16105. doi: 10.1038/ncomms16105.

36.

At the base of colinear Hox gene expression: cis-features and trans-factors orchestrating the initial phase of Hox cluster activation.

Neijts R, Deschamps J.

Dev Biol. 2017 Aug 15;428(2):293-299. doi: 10.1016/j.ydbio.2017.02.009. Review.

37.

Nanoparticle cellular uptake by dendritic wedge peptides: achieving single peptide facilitated delivery.

Breger JC, Muttenthaler M, Delehanty JB, Thompson DA, Oh E, Susumu K, Deschamps JR, Anderson GP, Field LD, Walper SA, Dawson PE, Medintz IL.

Nanoscale. 2017 Jul 27;9(29):10447-10464. doi: 10.1039/c7nr03362a.

PMID:
28703833
38.

Elucidating Surface Ligand-Dependent Kinetic Enhancement of Proteolytic Activity at Surface-Modified Quantum Dots.

Díaz SA, Sen S, Boeneman Gemmill K, Brown CW 3rd, Oh E, Susumu K, Stewart MH, Breger JC, Lasarte Aragonés G, Field LD, Deschamps JR, Král P, Medintz IL.

ACS Nano. 2017 Jun 27;11(6):5884-5896. doi: 10.1021/acsnano.7b01624. Epub 2017 Jun 12.

PMID:
28603969
39.

Quantum Dot-Peptide-Fullerene Bioconjugates for Visualization of in Vitro and in Vivo Cellular Membrane Potential.

Nag OK, Stewart MH, Deschamps JR, Susumu K, Oh E, Tsytsarev V, Tang Q, Efros AL, Vaxenburg R, Black BJ, Chen Y, O'Shaughnessy TJ, North SH, Field LD, Dawson PE, Pancrazio JJ, Medintz IL, Chen Y, Erzurumlu RS, Huston AL, Delehanty JB.

ACS Nano. 2017 Jun 27;11(6):5598-5613. doi: 10.1021/acsnano.7b00954. Epub 2017 May 30.

40.

One-pot sequential reaction to 2-substituted-phenanthridinones from N-methoxybenzamides.

Liang D, Sersen D, Yang C, Deschamps JR, Imler GH, Jiang C, Xue F.

Org Biomol Chem. 2017 May 23;15(20):4390-4398. doi: 10.1039/c7ob00649g.

PMID:
28475192
41.

Modulation of opioid receptor affinity and efficacy via N-substitution of 9β-hydroxy-5-(3-hydroxyphenyl)morphan: Synthesis and computer simulation study.

Truong PM, Hassan SA, Lee YS, Kopajtic TA, Katz JL, Chadderdon AM, Traynor JR, Deschamps JR, Jacobson AE, Rice KC.

Bioorg Med Chem. 2017 Apr 15;25(8):2406-2422. doi: 10.1016/j.bmc.2017.02.064. Epub 2017 Mar 1.

42.

Iodobenzene-Catalyzed Synthesis of Phenanthridinones via Oxidative C-H Amidation.

Liang D, Yu W, Nguyen N, Deschamps JR, Imler GH, Li Y, MacKerell AD Jr, Jiang C, Xue F.

J Org Chem. 2017 Apr 7;82(7):3589-3596. doi: 10.1021/acs.joc.7b00106. Epub 2017 Mar 10.

PMID:
28245353
43.

Comparison of biofilm formation and motility processes in arsenic-resistant Thiomonas spp. strains revealed divergent response to arsenite.

Farasin J, Koechler S, Varet H, Deschamps J, Dillies MA, Proux C, Erhardt M, Huber A, Jagla B, Briandet R, Coppée JY, Arsène-Ploetze F.

Microb Biotechnol. 2017 Jul;10(4):789-803. doi: 10.1111/1751-7915.12556. Epub 2017 Feb 7.

44.

Charte d’Ottawa : traduction ou trahison ?

Ferron C, Deschamps JP.

Sante Publique. 2016 Dec 19;28(6):715-716. French. No abstract available.

PMID:
28155762
45.

La Charte d’Ottawa a trente ans...

Deschamps JP.

Sante Publique. 2016 Dec 19;28(6):711. French. No abstract available.

PMID:
28155760
46.

Enantiospecific Allosteric Modulation of Cannabinoid 1 Receptor.

Laprairie RB, Kulkarni PM, Deschamps JR, Kelly MEM, Janero DR, Cascio MG, Stevenson LA, Pertwee RG, Kenakin TP, Denovan-Wright EM, Thakur GA.

ACS Chem Neurosci. 2017 Jun 21;8(6):1188-1203. doi: 10.1021/acschemneuro.6b00310. Epub 2017 Feb 7.

PMID:
28103441
47.

Cdx is crucial for the timing mechanism driving colinear Hox activation and defines a trunk segment in the Hox cluster topology.

Neijts R, Amin S, van Rooijen C, Deschamps J.

Dev Biol. 2017 Feb 15;422(2):146-154. doi: 10.1016/j.ydbio.2016.12.024. Epub 2016 Dec 29.

48.

Cdx and T Brachyury Co-activate Growth Signaling in the Embryonic Axial Progenitor Niche.

Amin S, Neijts R, Simmini S, van Rooijen C, Tan SC, Kester L, van Oudenaarden A, Creyghton MP, Deschamps J.

Cell Rep. 2016 Dec 20;17(12):3165-3177. doi: 10.1016/j.celrep.2016.11.069.

49.

Toward Understanding the Structural Basis of Partial Agonism at the Dopamine D3 Receptor.

Michino M, Boateng CA, Donthamsetti P, Yano H, Bakare OM, Bonifazi A, Ellenberger MP, Keck TM, Kumar V, Zhu C, Verma R, Deschamps JR, Javitch JA, Newman AH, Shi L.

J Med Chem. 2017 Jan 26;60(2):580-593. doi: 10.1021/acs.jmedchem.6b01148. Epub 2017 Jan 5.

50.

Efficient homogeneous illumination and optical sectioning for quantitative single-molecule localization microscopy.

Deschamps J, Rowald A, Ries J.

Opt Express. 2016 Nov 28;24(24):28080-28090. doi: 10.1364/OE.24.028080.

PMID:
27906373

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