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Items: 1 to 50 of 151

1.

Phase 1 dose-finding study of metformin in combination with concurrent cisplatin and radiotherapy in patients with locally advanced head and neck squamous cell cancer.

Gulati S, Desai J, Palackdharry SM, Morris JC, Zhu Z, Jandarov R, Riaz MK, Takiar V, Mierzwa M, Gutkind JS, Molinolo A, Desai PB, Sadraei NH, Wise-Draper TM.

Cancer. 2019 Oct 18. doi: 10.1002/cncr.32539. [Epub ahead of print]

PMID:
31626727
2.

Comorbidity burden and nonclinical factors associated with sinonasal cancer all-cause mortality.

Desai PB, Bukatko AR, Simpson MC, Adjei Boakye E, Greenberg JW, Ward GM, Walker RJ, Antisdel JL, Osazuwa Peters N.

Laryngoscope. 2019 Aug 14. doi: 10.1002/lary.28223. [Epub ahead of print]

PMID:
31411750
3.

Preclinical pharmacokinetic evaluation to facilitate repurposing of tyrosine kinase inhibitors nilotinib and imatinib as antiviral agents.

Ananthula HK, Parker S, Touchette E, Buller RM, Patel G, Kalman D, Salzer JS, Gallardo-Romero N, Olson V, Damon IK, Moir-Savitz T, Sallans L, Werner MH, Sherwin CM, Desai PB.

BMC Pharmacol Toxicol. 2018 Dec 4;19(1):80. doi: 10.1186/s40360-018-0270-x.

4.

Plasma and brain pharmacokinetics of letrozole and drug interaction studies with temozolomide in NOD-scid gamma mice and sprague dawley rats.

Arora P, Adams CH, Gudelsky G, DasGupta B, Desai PB.

Cancer Chemother Pharmacol. 2019 Jan;83(1):81-89. doi: 10.1007/s00280-018-3705-6. Epub 2018 Oct 24.

PMID:
30357450
5.

Ift25 is not a cystic kidney disease gene but is required for early steps of kidney development.

Desai PB, San Agustin JT, Stuck MW, Jonassen JA, Bates CM, Pazour GJ.

Mech Dev. 2018 Jun;151:10-17. doi: 10.1016/j.mod.2018.04.001. Epub 2018 Apr 4.

6.

Erratum for Mor et al., "Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids".

Mor V, Rella A, Farnoud AM, Singh A, Munshi M, Bryan A, Naseem S, Konopka JB, Ojima I, Bullesbach E, Ashbaugh A, Linke MJ, Cushion M, Collins M, Ananthula HK, Sallans L, Desai PB, Wiederhold NP, Fothergill AW, Kirkpatrick WR, Patterson T, Wong LH, Sinha S, Giaever G, Nislow C, Flaherty P, Pan X, Cesar GV, de Melo Tavares P, Frases S, Miranda K, Rodrigues ML, Luberto C, Nimrichter L, Del Poeta M.

MBio. 2018 Mar 13;9(2). pii: e00188-18. doi: 10.1128/mBio.00188-18. No abstract available.

7.

Acylhydrazones as Antifungal Agents Targeting the Synthesis of Fungal Sphingolipids.

Lazzarini C, Haranahalli K, Rieger R, Ananthula HK, Desai PB, Ashbaugh A, Linke MJ, Cushion MT, Ruzsicska B, Haley J, Ojima I, Del Poeta M.

Antimicrob Agents Chemother. 2018 Apr 26;62(5). pii: e00156-18. doi: 10.1128/AAC.00156-18. Print 2018 May.

8.

Granulosis Rubra Nasi Response to Topical Tacrolimus.

Taj FT, Vupperla D, Desai PB.

Case Rep Dermatol Med. 2017;2017:2519814. doi: 10.1155/2017/2519814. Epub 2017 Nov 29.

9.

Role and relevance of BRAF mutations in risk stratifying patients of papillary thyroid cancers along with a review of literature.

Krishnamurthy A, Ramshankar V, Murherkar K, Vidyarani S, Raghunandhan GC, Das A, Desai PB, Albert K.

Indian J Cancer. 2017 Jan-Mar;54(1):372-378. doi: 10.4103/ijc.IJC_182_17.

10.

Evaluation of Vancomycin Use in Late-Onset Neonatal Sepsis Using the Area Under the Concentration-Time Curve to the Minimum Inhibitory Concentration ≥400 Target.

Bhongsatiern J, Stockmann C, Roberts JK, Yu T, Korgenski KE, Spigarelli MG, Desai PB, Sherwin CM.

Ther Drug Monit. 2015 Dec;37(6):756-65. doi: 10.1097/FTD.0000000000000216.

11.

Renal Function Descriptors in Neonates: Which Creatinine-Based Formula Best Describes Vancomycin Clearance?

Bhongsatiern J, Stockmann C, Yu T, Constance JE, Moorthy G, Spigarelli MG, Desai PB, Sherwin CM.

J Clin Pharmacol. 2016 May;56(5):528-40. doi: 10.1002/jcph.650. Epub 2015 Dec 18. Review.

PMID:
26412385
12.

Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids.

Mor V, Rella A, Farnoud AM, Singh A, Munshi M, Bryan A, Naseem S, Konopka JB, Ojima I, Bullesbach E, Ashbaugh A, Linke MJ, Cushion M, Collins M, Ananthula HK, Sallans L, Desai PB, Wiederhold NP, Fothergill AW, Kirkpatrick WR, Patterson T, Wong LH, Sinha S, Giaever G, Nislow C, Flaherty P, Pan X, Cesar GV, de Melo Tavares P, Frases S, Miranda K, Rodrigues ML, Luberto C, Nimrichter L, Del Poeta M.

MBio. 2015 Jun 23;6(3):e00647. doi: 10.1128/mBio.00647-15. Erratum in: MBio. 2018 Mar 13;9(2):.

13.

Safety, tolerability and pharmacokinetics of 2-pyridylacetic acid, a major metabolite of betahistine, in a phase 1 dose escalation study in subjects with ADHD.

Moorthy G, Sallee F, Gabbita P, Zemlan F, Sallans L, Desai PB.

Biopharm Drug Dispos. 2015 Oct;36(7):429-39. doi: 10.1002/bdd.1955. Epub 2015 May 22.

PMID:
25904220
14.

Preclinical pharmacological evaluation of letrozole as a novel treatment for gliomas.

Dave N, Chow LM, Gudelsky GA, LaSance K, Qi X, Desai PB.

Mol Cancer Ther. 2015 Apr;14(4):857-64. doi: 10.1158/1535-7163.MCT-14-0743. Epub 2015 Feb 18.

15.

Chlamydomonas axonemal dynein assembly locus ODA8 encodes a conserved flagellar protein needed for cytoplasmic maturation of outer dynein arm complexes.

Desai PB, Freshour JR, Mitchell DR.

Cytoskeleton (Hoboken). 2015 Jan;72(1):16-28. doi: 10.1002/cm.21206. Epub 2015 Feb 7.

16.

A549 cells adapted to high nitric oxide show reduced surface CEACAM expression and altered adhesion and migration properties.

Aqil M, Elseth KM, Arjunakani A, Nebres P, Amegashie CP, Thanki DH, Desai PB, Radosevich JA.

Tumour Biol. 2015 Mar;36(3):1871-9. doi: 10.1007/s13277-014-2789-9. Epub 2014 Dec 11.

PMID:
25500969
17.

Manipulation of olfactory tight junctions using papaverine to enhance intranasal delivery of gemcitabine to the brain.

Krishan M, Gudelsky GA, Desai PB, Genter MB.

Drug Deliv. 2014 Feb;21(1):8-16. doi: 10.3109/10717544.2013.840017. Epub 2013 Oct 14.

18.

The pharmacokinetics of letrozole in brain and brain tumor in rats with orthotopically implanted C6 glioma, assessed using intracerebral microdialysis.

Dave N, Gudelsky GA, Desai PB.

Cancer Chemother Pharmacol. 2013 Aug;72(2):349-57. doi: 10.1007/s00280-013-2205-y. Epub 2013 Jun 9.

PMID:
23748921
19.

The pharmacokinetics of acyl, des-acyl, and total ghrelin in healthy human subjects.

Tong J, Dave N, Mugundu GM, Davis HW, Gaylinn BD, Thorner MO, Tschöp MH, D'Alessio D, Desai PB.

Eur J Endocrinol. 2013 May 2;168(6):821-8. doi: 10.1530/EJE-13-0072. Print 2013 Jun.

20.

Quantification of human hepatocyte cytochrome P450 enzymes and transporters induced by HIV protease inhibitors using newly validated LC-MS/MS cocktail assays and RT-PCR.

Liu L, Mugundu GM, Kirby BJ, Samineni D, Desai PB, Unadkat JD.

Biopharm Drug Dispos. 2012 May;33(4):207-17. doi: 10.1002/bdd.1788. Epub 2012 May 2.

PMID:
22498895
21.

Relationship between serum lithium, salivary lithium, and urinary lithium in patients on lithium therapy.

Shetty SJ, Desai PB, Patil NM, Nayak RB.

Biol Trace Elem Res. 2012 Jun;147(1-3):59-62. doi: 10.1007/s12011-011-9295-3. Epub 2011 Dec 8.

PMID:
22161502
22.

Assessment of the impact of CYP3A polymorphisms on the formation of α-hydroxytamoxifen and N-desmethyltamoxifen in human liver microsomes.

Mugundu GM, Sallans L, Guo Y, Shaughnessy EA, Desai PB.

Drug Metab Dispos. 2012 Feb;40(2):389-96. doi: 10.1124/dmd.111.039388. Epub 2011 Nov 17.

PMID:
22096084
23.

Steady-state pharmacokinetic interactions of darunavir/ritonavir with lipid-lowering agent rosuvastatin.

Samineni D, Desai PB, Sallans L, Fichtenbaum CJ.

J Clin Pharmacol. 2012 Jun;52(6):922-31. doi: 10.1177/0091270011407494. Epub 2011 Jun 28.

PMID:
21712498
24.

Visfatin--a review.

Sonoli SS, Shivprasad S, Prasad CV, Patil AB, Desai PB, Somannavar MS.

Eur Rev Med Pharmacol Sci. 2011 Jan;15(1):9-14. Review.

PMID:
21381495
26.

Oxidative stress and enzymatic antioxidant status in rheumatoid arthritis: a case control study.

Desai PB, Manjunath S, Kadi S, Chetana K, Vanishree J.

Eur Rev Med Pharmacol Sci. 2010 Nov;14(11):959-67.

PMID:
21284345
27.

Markers of renal function tests.

Gowda S, Desai PB, Kulkarni SS, Hull VV, Math AA, Vernekar SN.

N Am J Med Sci. 2010 Apr;2(4):170-3.

28.
29.

A review on laboratory liver function tests.

Gowda S, Desai PB, Hull VV, Math AA, Vernekar SN, Kulkarni SS.

Pan Afr Med J. 2009 Nov 22;3:17.

31.

Role of human pregnane X receptor in tamoxifen- and 4-hydroxytamoxifen-mediated CYP3A4 induction in primary human hepatocytes and LS174T cells.

Sane RS, Buckley DJ, Buckley AR, Nallani SC, Desai PB.

Drug Metab Dispos. 2008 May;36(5):946-54. doi: 10.1124/dmd.107.018598. Epub 2008 Feb 25.

PMID:
18299335
32.

Pharmacokinetics of gemcitabine in tumor and non-tumor extracellular fluid of brain: an in vivo assessment in rats employing intracerebral microdialysis.

Apparaju SK, Gudelsky GA, Desai PB.

Cancer Chemother Pharmacol. 2008 Feb;61(2):223-9. Epub 2007 Apr 19.

PMID:
17443325
33.

In vitro methods in human drug biotransformation research: implications for cancer chemotherapy.

Hariparsad N, Sane RS, Strom SC, Desai PB.

Toxicol In Vitro. 2006 Mar;20(2):135-53. Epub 2005 Dec 15. Review.

PMID:
16359840
34.

Metabolism and Pharmacokinetics of Anti-Cancer Drugs.

Desai PB, Sane RS.

Toxicol In Vitro. 2006 Mar;20(2):133-4. No abstract available.

PMID:
16321499
35.

Pharmacokinetics of a slow-release formulation of soybean isoflavones in healthy postmenopausal women.

Setchell KD, Brzezinski A, Brown NM, Desai PB, Melhem M, Meredith T, Zimmer-Nechimias L, Wolfe B, Cohen Y, Blatt Y.

J Agric Food Chem. 2005 Mar 23;53(6):1938-44.

PMID:
15769117
36.

Fibrinogen-coated droplets of olive oil for delivery of docetaxel to a fibrin(ogen)-rich ascites form of a murine mammary tumor.

Einhaus CM, Retzinger AC, Perrotta AO, Dentler MD, Jakate AS, Desai PB, Retzinger GS.

Clin Cancer Res. 2004 Oct 15;10(20):7001-10.

37.

Induction of CYP3A4 by efavirenz in primary human hepatocytes: comparison with rifampin and phenobarbital.

Hariparsad N, Nallani SC, Sane RS, Buckley DJ, Buckley AR, Desai PB.

J Clin Pharmacol. 2004 Nov;44(11):1273-81.

PMID:
15496645
38.

Differences in the induction of cytochrome P450 3A4 by taxane anticancer drugs, docetaxel and paclitaxel, assessed employing primary human hepatocytes.

Nallani SC, Goodwin B, Buckley AR, Buckley DJ, Desai PB.

Cancer Chemother Pharmacol. 2004 Sep;54(3):219-29. Epub 2004 Jun 3.

PMID:
15175893
39.

Dose-dependent induction of cytochrome P450 (CYP) 3A4 and activation of pregnane X receptor by topiramate.

Nallani SC, Glauser TA, Hariparsad N, Setchell K, Buckley DJ, Buckley AR, Desai PB.

Epilepsia. 2003 Dec;44(12):1521-8.

40.
41.

Total oral reconstruction for cancers associated with advanced oral submucous fibrosis.

Cunha-Gomes D, Kavarana NM, Choudhari C, Rajendraprasad JS, Bhathena HM, Desai PB, Vyas JJ, Gangwal S.

Ann Plast Surg. 2003 Sep;51(3):283-9.

PMID:
12966241
42.

In vitro and in vivo percutaneous absorption of catechol.

Jung CT, Wickett RR, Desai PB, Bronaugh RL.

Food Chem Toxicol. 2003 Jun;41(6):885-95.

PMID:
12738194
43.

Induction of cytochrome P450 3A by paclitaxel in mice: pivotal role of the nuclear xenobiotic receptor, pregnane X receptor.

Nallani SC, Goodwin B, Maglich JM, Buckley DJ, Buckley AR, Desai PB.

Drug Metab Dispos. 2003 May;31(5):681-4.

PMID:
12695359
44.

Bioavailability, disposition, and dose-response effects of soy isoflavones when consumed by healthy women at physiologically typical dietary intakes.

Setchell KD, Brown NM, Desai PB, Zimmer-Nechimias L, Wolfe B, Jakate AS, Creutzinger V, Heubi JE.

J Nutr. 2003 Apr;133(4):1027-35.

PMID:
12672914
45.

Induction of olfactory mucosal and liver metabolism of lidocaine by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Genter MB, Apparaju S, Desai PB.

J Biochem Mol Toxicol. 2002;16(3):128-34.

PMID:
12112712
46.

Cancer control efforts in the Indian subcontinent.

Desai PB.

Jpn J Clin Oncol. 2002 Mar;32 Suppl:S13-6.

PMID:
11959872
47.

Induction of cytochrome P450 3A4 in primary human hepatocytes and activation of the human pregnane X receptor by tamoxifen and 4-hydroxytamoxifen.

Desai PB, Nallani SC, Sane RS, Moore LB, Goodwin BJ, Buckley DJ, Buckley AR.

Drug Metab Dispos. 2002 May;30(5):608-12.

PMID:
11950795
48.

Bioavailability study of a 1200 mg miconazole nitrate vaginal ovule in healthy female adults.

Stevens RE, Konsil J, Verrill SS, Roy P, Desai PB, Upmalis DH, Cone FL.

J Clin Pharmacol. 2002 Jan;42(1):52-60.

PMID:
11808824
49.
50.

Characterization of lidocaine metabolism by rat nasal microsomes: implications for nasal drug delivery.

Deshpande VS, Genter MB, Jung C, Desai PB.

Eur J Drug Metab Pharmacokinet. 1999 Apr-Jun;24(2):177-82.

PMID:
10510747

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