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Items: 36


Trained Immunity and Susceptibility to HIV.

Derrick SC.

Clin Vaccine Immunol. 2017 Jan 5;24(1). pii: e00509-16. doi: 10.1128/CVI.00509-16. Print 2017 Jan.


A simplified mycobacterial growth inhibition assay (MGIA) using direct infection of mouse splenocytes and the MGIT system.

Yang AL, Schmidt TE, Stibitz S, Derrick SC, Morris SL, Parra M.

J Microbiol Methods. 2016 Dec;131:7-9. doi: 10.1016/j.mimet.2016.09.010. Epub 2016 Sep 17.


Co-expression of Interleukin-15 Enhances the Protective Immune Responses Induced by Immunization with a Murine Malaria MVA-Based Vaccine Encoding the Circumsporozoite Protein.

Parra M, Liu X, Derrick SC, Yang A, Molina-Cruz A, Barillas-Mury C, Zheng H, Thao Pham P, Sedegah M, Belmonte A, Litilit DD, Waldmann TA, Kumar S, Morris SL, Perera LP.

PLoS One. 2015 Oct 27;10(10):e0141141. doi: 10.1371/journal.pone.0141141. eCollection 2015.


Effect of cationic liposomes on BCG trafficking and vaccine-induced immune responses following a subcutaneous immunization in mice.

Derrick SC, Yang A, Parra M, Kolibab K, Morris SL.

Vaccine. 2015 Jan 1;33(1):126-32. doi: 10.1016/j.vaccine.2014.11.004. Epub 2014 Nov 15.


Intranasal administration of Mycobacterium bovis BCG induces superior protection against aerosol infection with Mycobacterium tuberculosis in mice.

Derrick SC, Kolibab K, Yang A, Morris SL.

Clin Vaccine Immunol. 2014 Oct;21(10):1443-51. doi: 10.1128/CVI.00394-14. Epub 2014 Aug 20.


Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk.

Mayer-Barber KD, Andrade BB, Oland SD, Amaral EP, Barber DL, Gonzales J, Derrick SC, Shi R, Kumar NP, Wei W, Yuan X, Zhang G, Cai Y, Babu S, Catalfamo M, Salazar AM, Via LE, Barry CE 3rd, Sher A.

Nature. 2014 Jul 3;511(7507):99-103. doi: 10.1038/nature13489. Epub 2014 Jun 25.


Time to detection of Mycobacterium tuberculosis using the MGIT 320 system correlates with colony counting in preclinical testing of new vaccines.

Kolibab K, Yang A, Parra M, Derrick SC, Morris SL.

Clin Vaccine Immunol. 2014 Mar;21(3):453-5. doi: 10.1128/CVI.00742-13. Epub 2013 Dec 26.


The transcription factor T-bet regulates parasitemia and promotes pathogenesis during Plasmodium berghei ANKA murine malaria.

Oakley MS, Sahu BR, Lotspeich-Cole L, Solanki NR, Majam V, Pham PT, Banerjee R, Kozakai Y, Derrick SC, Kumar S, Morris SL.

J Immunol. 2013 Nov 1;191(9):4699-708. doi: 10.4049/jimmunol.1300396. Epub 2013 Sep 27.


Immunogenicity and protective efficacy of novel Mycobacterium tuberculosis antigens.

Derrick SC, Yabe IM, Yang A, Kolibab K, Hollingsworth B, Kurtz SL, Morris S.

Vaccine. 2013 Sep 23;31(41):4641-6. doi: 10.1016/j.vaccine.2013.07.032. Epub 2013 Jul 30.


Molecular analysis of non-specific protection against murine malaria induced by BCG vaccination.

Parra M, Liu X, Derrick SC, Yang A, Tian J, Kolibab K, Kumar S, Morris SL.

PLoS One. 2013 Jul 4;8(7):e66115. doi: 10.1371/journal.pone.0066115. Print 2013.


Characterization of an intracellular ATP assay for evaluating the viability of live attenuated mycobacterial vaccine preparations.

Kolibab K, Derrick SC, Jacobs WR, Morris SL.

J Microbiol Methods. 2012 Sep;90(3):245-9. doi: 10.1016/j.mimet.2012.05.015. Epub 2012 May 28.


Formulation of a mmaA4 gene deletion mutant of Mycobacterium bovis BCG in cationic liposomes significantly enhances protection against tuberculosis.

Derrick SC, Dao D, Yang A, Kolibab K, Jacobs WR, Morris SL.

PLoS One. 2012;7(3):e32959. doi: 10.1371/journal.pone.0032959. Epub 2012 Mar 19.


Malaria infections do not compromise vaccine-induced immunity against tuberculosis in mice.

Parra M, Derrick SC, Yang A, Tian J, Kolibab K, Oakley M, Perera LP, Jacobs WR, Kumar S, Morris SL.

PLoS One. 2011;6(12):e28164. doi: 10.1371/journal.pone.0028164. Epub 2011 Dec 19.


Sensitivity to isoniazid of Mycobacterium bovis BCG strains and BCG disseminated disease isolates.

Kolibab K, Derrick SC, Morris SL.

J Clin Microbiol. 2011 Jun;49(6):2380-1. doi: 10.1128/JCM.00648-11. Epub 2011 Apr 20. No abstract available.


Vaccine-induced anti-tuberculosis protective immunity in mice correlates with the magnitude and quality of multifunctional CD4 T cells.

Derrick SC, Yabe IM, Yang A, Morris SL.

Vaccine. 2011 Apr 5;29(16):2902-9. doi: 10.1016/j.vaccine.2011.02.010. Epub 2011 Feb 21.


Highly persistent and effective prime/boost regimens against tuberculosis that use a multivalent modified vaccine virus Ankara-based tuberculosis vaccine with interleukin-15 as a molecular adjuvant.

Kolibab K, Yang A, Derrick SC, Waldmann TA, Perera LP, Morris SL.

Clin Vaccine Immunol. 2010 May;17(5):793-801. doi: 10.1128/CVI.00006-10. Epub 2010 Mar 31.


A practical in vitro growth inhibition assay for the evaluation of TB vaccines.

Kolibab K, Parra M, Yang AL, Perera LP, Derrick SC, Morris SL.

Vaccine. 2009 Dec 11;28(2):317-22. doi: 10.1016/j.vaccine.2009.10.047. Epub 2009 Oct 29.


Novel recombinant BCG expressing perfringolysin O and the over-expression of key immunodominant antigens; pre-clinical characterization, safety and protection against challenge with Mycobacterium tuberculosis.

Sun R, Skeiky YA, Izzo A, Dheenadhayalan V, Imam Z, Penn E, Stagliano K, Haddock S, Mueller S, Fulkerson J, Scanga C, Grover A, Derrick SC, Morris S, Hone DM, Horwitz MA, Kaufmann SH, Sadoff JC.

Vaccine. 2009 Jul 16;27(33):4412-23. doi: 10.1016/j.vaccine.2009.05.048. Epub 2009 Jun 2.


A multi-valent vaccinia virus-based tuberculosis vaccine molecularly adjuvanted with interleukin-15 induces robust immune responses in mice.

Perera PY, Derrick SC, Kolibab K, Momoi F, Yamamoto M, Morris SL, Waldmann TA, Perera LP.

Vaccine. 2009 Mar 26;27(15):2121-7. doi: 10.1016/j.vaccine.2009.01.132. Epub 2009 Feb 6.


Early pulmonary cytokine and chemokine responses in mice immunized with three different vaccines against Mycobacterium tuberculosis determined by PCR array.

Lim J, Derrick SC, Kolibab K, Yang AL, Porcelli S, Jacobs WR, Morris SL.

Clin Vaccine Immunol. 2009 Jan;16(1):122-6. doi: 10.1128/CVI.00359-08. Epub 2008 Nov 26.


The safety of post-exposure vaccination of mice infected with Mycobacterium tuberculosis.

Derrick SC, Perera LP, Dheenadhayalan V, Yang A, Kolibab K, Morris SL.

Vaccine. 2008 Nov 11;26(48):6092-8. doi: 10.1016/j.vaccine.2008.09.011. Epub 2008 Sep 20.


Mycobacterium bovis BCG immunization induces protective immunity against nine different Mycobacterium tuberculosis strains in mice.

Jeon BY, Derrick SC, Lim J, Kolibab K, Dheenadhayalan V, Yang AL, Kreiswirth B, Morris SL.

Infect Immun. 2008 Nov;76(11):5173-80. doi: 10.1128/IAI.00019-08. Epub 2008 Aug 18.


Enhanced priming of adaptive immunity by a proapoptotic mutant of Mycobacterium tuberculosis.

Hinchey J, Lee S, Jeon BY, Basaraba RJ, Venkataswamy MM, Chen B, Chan J, Braunstein M, Orme IM, Derrick SC, Morris SL, Jacobs WR Jr, Porcelli SA.

J Clin Invest. 2007 Aug;117(8):2279-88.


The ESAT6 protein of Mycobacterium tuberculosis induces apoptosis of macrophages by activating caspase expression.

Derrick SC, Morris SL.

Cell Microbiol. 2007 Jun;9(6):1547-55. Epub 2007 Feb 9.


Characterization of the protective T-cell response generated in CD4-deficient mice by a live attenuated Mycobacterium tuberculosis vaccine.

Derrick SC, Evering TH, Sambandamurthy VK, Jalapathy KV, Hsu T, Chen B, Chen M, Russell RG, Junqueira-Kipnis AP, Orme IM, Porcelli SA, Jacobs WR Jr, Morris SL.

Immunology. 2007 Feb;120(2):192-206. Epub 2006 Oct 31.


Mycobacterium tuberculosis DeltaRD1 DeltapanCD: a safe and limited replicating mutant strain that protects immunocompetent and immunocompromised mice against experimental tuberculosis.

Sambandamurthy VK, Derrick SC, Hsu T, Chen B, Larsen MH, Jalapathy KV, Chen M, Kim J, Porcelli SA, Chan J, Morris SL, Jacobs WR Jr.

Vaccine. 2006 Sep 11;24(37-39):6309-20. Epub 2006 Jun 12.


Novel conjugate of moxifloxacin and carboxymethylated glucan with enhanced activity against Mycobacterium tuberculosis.

Schwartz YS, Dushkin MI, Vavilin VA, Melnikova EV, Khoschenko OM, Kozlov VA, Agafonov AP, Alekseev AY, Rassadkin Y, Shestapalov AM, Azaev MS, Saraev DV, Filimonov PN, Kurunov Y, Svistelnik AV, Krasnov VA, Pathak A, Derrick SC, Reynolds RC, Morris S, Blinov VM.

Antimicrob Agents Chemother. 2006 Jun;50(6):1982-8.


Protection against an aerogenic Mycobacterium tuberculosis infection in BCG-immunized and DNA-vaccinated mice is associated with early type I cytokine responses.

Goter-Robinson C, Derrick SC, Yang AL, Jeon BY, Morris SL.

Vaccine. 2006 Apr 24;24(17):3522-9. Epub 2006 Feb 20.


Long-term protection against tuberculosis following vaccination with a severely attenuated double lysine and pantothenate auxotroph of Mycobacterium tuberculosis.

Sambandamurthy VK, Derrick SC, Jalapathy KV, Chen B, Russell RG, Morris SL, Jacobs WR Jr.

Infect Immun. 2005 Feb;73(2):1196-203.


The primary mechanism of attenuation of bacillus Calmette-Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissue.

Hsu T, Hingley-Wilson SM, Chen B, Chen M, Dai AZ, Morin PM, Marks CB, Padiyar J, Goulding C, Gingery M, Eisenberg D, Russell RG, Derrick SC, Collins FM, Morris SL, King CH, Jacobs WR Jr.

Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12420-5. Epub 2003 Oct 13.


Induction of macrophage binding to virally infected cells by low levels of lipopolysaccharide.

Derrick SC, LeBlanc PA.

J Leukoc Biol. 1995 Apr;57(4):569-73.


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