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Items: 1 to 50 of 67

1.

Platelet-derived growth factor receptor β activation and regulation in murine myelofibrosis.

Kramer F, Dernedde J, Mezheyeuski A, Tauber R, Micke P, Kappert K.

Haematologica. 2019 Oct 31. pii: haematol.2019.226332. doi: 10.3324/haematol.2019.226332. [Epub ahead of print]

2.

dPGS Regulates the Phenotype of Macrophages via Metabolic Switching.

Wu H, Reimann S, Siddiqui S, Haag R, Siegmund B, Dernedde J, Glauben R.

Macromol Biosci. 2019 Dec;19(12):e1900184. doi: 10.1002/mabi.201900184. Epub 2019 Oct 21.

PMID:
31631571
3.

Sulfated Dendritic Polyglycerol Is a Potent Complement Inhibitor.

Silberreis K, Niesler N, Rades N, Haag R, Dernedde J.

Biomacromolecules. 2019 Oct 14;20(10):3809-3818. doi: 10.1021/acs.biomac.9b00889. Epub 2019 Sep 9.

PMID:
31461260
4.

Design and Synthesis of PEG-Oligoglycerol Sulfates as Multivalent Inhibitors for the Scavenger Receptor LOX-1.

Kumari S, Achazi K, Dey P, Haag R, Dernedde J.

Biomacromolecules. 2019 Mar 11;20(3):1157-1166. doi: 10.1021/acs.biomac.8b01416. Epub 2019 Feb 4.

PMID:
30642176
5.

Biodegradable Polyglycerol Sulfates Exhibit Promising Features for Anti-inflammatory Applications.

Ferraro M, Silberreis K, Mohammadifar E, Neumann F, Dernedde J, Haag R.

Biomacromolecules. 2018 Dec 10;19(12):4524-4533. doi: 10.1021/acs.biomac.8b01100. Epub 2018 Nov 26.

PMID:
30412396
6.

Droplet-Based Microfluidic Templating of Polyglycerol-Based Microgels for the Encapsulation of Cells: A Comparative Study.

Kapourani E, Neumann F, Achazi K, Dernedde J, Haag R.

Macromol Biosci. 2018 Oct;18(10):e1800116. doi: 10.1002/mabi.201800116. Epub 2018 Jul 10.

PMID:
29992778
7.

Interactions of Fullerene-Polyglycerol Sulfates at Viral and Cellular Interfaces.

Donskyi I, Drüke M, Silberreis K, Lauster D, Ludwig K, Kühne C, Unger W, Böttcher C, Herrmann A, Dernedde J, Adeli M, Haag R.

Small. 2018 Apr;14(17):e1800189. doi: 10.1002/smll.201800189. Epub 2018 Mar 25.

PMID:
29575636
8.

Anti-inflammatory properties of GLPss58, a sulfated polysaccharide from Ganoderma lucidum.

Zhang K, Liu Y, Zhao X, Tang Q, Dernedde J, Zhang J, Fan H.

Int J Biol Macromol. 2018 Feb;107(Pt A):486-493. doi: 10.1016/j.ijbiomac.2017.09.015. Epub 2017 Sep 7.

PMID:
28890375
9.

Heterobifunctional Dyes: Highly Fluorescent Linkers Based on Cyanine Dyes.

Wycisk V, Achazi K, Hirsch O, Kuehne C, Dernedde J, Haag R, Licha K.

ChemistryOpen. 2017 Apr 13;6(3):437-446. doi: 10.1002/open.201700013. eCollection 2017 Jun.

10.

Reducing Macro- and Microheterogeneity of N-Glycans Enables the Crystal Structure of the Lectin and EGF-Like Domains of Human L-Selectin To Be Solved at 1.9 Å Resolution.

Wedepohl S, Dernedde J, Vahedi-Faridi A, Tauber R, Saenger W, Bulut H.

Chembiochem. 2017 Jul 4;18(13):1338-1345. doi: 10.1002/cbic.201700220. Epub 2017 Jun 6.

PMID:
28489325
11.

Polyvalent 2D Entry Inhibitors for Pseudorabies and African Swine Fever Virus.

Ziem B, Rahn J, Donskyi I, Silberreis K, Cuellar L, Dernedde J, Keil G, Mettenleiter TC, Haag R.

Macromol Biosci. 2017 Jun;17(6). doi: 10.1002/mabi.201600499. Epub 2017 Mar 15.

PMID:
28296132
12.

Noncharged and Charged Monodendronised Perylene Bisimides as Highly Fluorescent Labels and their Bioconjugates.

Huth K, Heek T, Achazi K, Kühne C, Urner LH, Pagel K, Dernedde J, Haag R.

Chemistry. 2017 Apr 6;23(20):4849-4862. doi: 10.1002/chem.201605847. Epub 2017 Mar 20.

PMID:
28128483
13.

Single-Step Purification of Monomeric l-Selectin via Aptamer Affinity Chromatography.

Kuehne C, Wedepohl S, Dernedde J.

Sensors (Basel). 2017 Jan 24;17(2). pii: E226. doi: 10.3390/s17020226.

14.

Mannose-Functionalized Hyperbranched Polyglycerol Loaded with Zinc Porphyrin: Investigation of the Multivalency Effect in Antibacterial Photodynamic Therapy.

Staegemann MH, Gitter B, Dernedde J, Kuehne C, Haag R, Wiehe A.

Chemistry. 2017 Mar 17;23(16):3918-3930. doi: 10.1002/chem.201605236. Epub 2017 Feb 20.

PMID:
28029199
15.

Polymeric Selectin Ligands Mimicking Complex Carbohydrates: From Selectin Binders to Modifiers of Macrophage Migration.

Moog KE, Barz M, Bartneck M, Beceren-Braun F, Mohr N, Wu Z, Braun L, Dernedde J, Liehn EA, Tacke F, Lammers T, Kunz H, Zentel R.

Angew Chem Int Ed Engl. 2017 Jan 24;56(5):1416-1421. doi: 10.1002/anie.201610395. Epub 2016 Dec 22.

PMID:
28005299
16.

Responsive Contrast Agents: Synthesis and Characterization of a Tunable Series of pH-Sensitive Near-Infrared Pentamethines.

Wycisk V, Achazi K, Hillmann P, Hirsch O, Kuehne C, Dernedde J, Haag R, Licha K.

ACS Omega. 2016 Nov 30;1(5):808-817. doi: 10.1021/acsomega.6b00182. Epub 2016 Nov 4.

17.

Significantly enhanced proteolytic activity of cyclen complexes by monoalkylation.

Perera-Bobusch C, Hormann J, Weise C, Wedepohl S, Dernedde J, Kulak N.

Dalton Trans. 2016 Jul 14;45(26):10500-4. doi: 10.1039/c6dt00681g. Epub 2016 Jun 9.

PMID:
27277522
18.

In Vivo Imaging of Fluorescent Probes Linked to Antibodies Against Human and Rat Vascular Endothelial Growth Factor.

Meyer JH, Cunea A, Licha K, Welker P, Sonntag-Bensch D, Wafula P, Dernedde J, Fimmers R, Holz FG, Schmitz-Valckenberg S.

Invest Ophthalmol Vis Sci. 2016 Feb;57(2):759-70. doi: 10.1167/iovs.15-18118.

PMID:
26927569
19.

Synthesis, Photophysical, and Biological Evaluation of Sulfated Polyglycerol Dendronized Perylenebisimides (PBIs)--A Promising Platform for Anti-Inflammatory Theranostic Agents?

Heek T, Kühne C, Depner H, Achazi K, Dernedde J, Haag R.

Bioconjug Chem. 2016 Mar 16;27(3):727-36. doi: 10.1021/acs.bioconjchem.5b00683. Epub 2016 Mar 3.

PMID:
26890394
20.

Structural requirements of mono- and multivalent L-selectin blocking aptamers for enhanced receptor inhibition in vitro and in vivo.

Riese SB, Buscher K, Enders S, Kuehne C, Tauber R, Dernedde J.

Nanomedicine. 2016 May;12(4):901-908. doi: 10.1016/j.nano.2015.12.379. Epub 2016 Jan 7.

PMID:
26772426
21.

Detecting and Quantifying Biomolecular Interactions of a Dendritic Polyglycerol Sulfate Nanoparticle Using Fluorescence Lifetime Measurements.

Boreham A, Pikkemaat J, Volz P, Brodwolf R, Kuehne C, Licha K, Haag R, Dernedde J, Alexiev U.

Molecules. 2015 Dec 24;21(1):E22. doi: 10.3390/molecules21010022.

22.

Effects of dendritic polyglycerol sulfate on articular chondrocytes.

Schneider T, Welker P, Haag R, Dernedde J, Hug T, Licha K, Kohl B, Arens S, Ertel W, Schulze-Tanzil G.

Inflamm Res. 2015 Nov;64(11):917-28. doi: 10.1007/s00011-015-0875-0. Epub 2015 Sep 9.

PMID:
26350038
23.

Shell Cleavable Dendritic Polyglycerol Sulfates Show High Anti-Inflammatory Properties by Inhibiting L-Selectin Binding and Complement Activation.

Reimann S, Gröger D, Kühne C, Riese SB, Dernedde J, Haag R.

Adv Healthc Mater. 2015 Oct;4(14):2154-2162. doi: 10.1002/adhm.201500503. Epub 2015 Aug 11.

PMID:
26259636
24.

Orthogonal dual-modification of proteins for the engineering of multivalent protein scaffolds.

Mühlberg M, Hoesl MG, Kuehne C, Dernedde J, Budisa N, Hackenberger CPR.

Beilstein J Org Chem. 2015 May 13;11:784-791. doi: 10.3762/bjoc.11.88. eCollection 2015.

25.

Synthesis of multivalent carbohydrate mimetics with aminopolyol end groups and their evaluation as L-selectin inhibitors.

Salta J, Dernedde J, Reissig HU.

Beilstein J Org Chem. 2015 May 5;11:638-46. doi: 10.3762/bjoc.11.72. eCollection 2015.

26.

Size dependence of steric shielding and multivalency effects for globular binding inhibitors.

Vonnemann J, Liese S, Kuehne C, Ludwig K, Dernedde J, Böttcher C, Netz RR, Haag R.

J Am Chem Soc. 2015 Feb 25;137(7):2572-9. doi: 10.1021/ja5114084. Epub 2015 Feb 12.

PMID:
25623606
27.

Cupulin is a zona pellucida-like domain protein and major component of the cupula from the inner ear.

Dernedde J, Weise C, Müller EC, Hagiwara A, Bachmann S, Suzuki M, Reutter W, Tauber R, Scherer H.

PLoS One. 2014 Nov 4;9(11):e111917. doi: 10.1371/journal.pone.0111917. eCollection 2014.

28.

Multivalent anchored and crosslinked hyperbranched polyglycerol monolayers as antifouling coating for titanium oxide surfaces.

Wei Q, Krysiak S, Achazi K, Becherer T, Noeske PM, Paulus F, Liebe H, Grunwald I, Dernedde J, Hartwig A, Hugel T, Haag R.

Colloids Surf B Biointerfaces. 2014 Oct 1;122:684-692. doi: 10.1016/j.colsurfb.2014.08.001. Epub 2014 Aug 10.

PMID:
25189471
29.

Enzymatically cross-linked hyperbranched polyglycerol hydrogels as scaffolds for living cells.

Wu C, Strehmel C, Achazi K, Chiappisi L, Dernedde J, Lensen MC, Gradzielski M, Ansorge-Schumacher MB, Haag R.

Biomacromolecules. 2014 Nov 10;15(11):3881-90. doi: 10.1021/bm500705x. Epub 2014 Oct 7.

PMID:
25144348
30.

Iron oxide nanoparticles stabilized with dendritic polyglycerols as selective MRI contrast agents.

Nordmeyer D, Stumpf P, Gröger D, Hofmann A, Enders S, Riese SB, Dernedde J, Taupitz M, Rauch U, Haag R, Rühl E, Graf C.

Nanoscale. 2014 Aug 21;6(16):9646-54. doi: 10.1039/c3nr04793h.

PMID:
24991655
31.

Chemoenzymatic synthesis of functional sialyl Lewis(x) mimetics with a heteroaromatic core.

Schlemmer C, Wiebe C, Ferenc D, Kowalczyk D, Wedepohl S, Ziegelmüller P, Dernedde J, Opatz T.

Chem Asian J. 2014 Aug;9(8):2119-25. doi: 10.1002/asia.201402118. Epub 2014 May 30.

32.

Polyglycerolsulfate functionalized gold nanorods as optoacoustic signal nanoamplifiers for in vivo bioimaging of rheumatoid arthritis.

Vonnemann J, Beziere N, Böttcher C, Riese SB, Kuehne C, Dernedde J, Licha K, von Schacky C, Kosanke Y, Kimm M, Meier R, Ntziachristos V, Haag R.

Theranostics. 2014 Mar 20;4(6):629-41. doi: 10.7150/thno.8518. eCollection 2014.

33.

A crucial role of L-selectin in C protein-induced experimental polymyositis in mice.

Oishi K, Hamaguchi Y, Matsushita T, Hasegawa M, Okiyama N, Dernedde J, Weinhart M, Haag R, Tedder TF, Takehara K, Kohsaka H, Fujimoto M.

Arthritis Rheumatol. 2014 Jul;66(7):1864-71. doi: 10.1002/art.38630.

34.

The effect of polyglycerol sulfate branching on inflammatory processes.

Paulus F, Schulze R, Steinhilber D, Zieringer M, Steinke I, Welker P, Licha K, Wedepohl S, Dernedde J, Haag R.

Macromol Biosci. 2014 May;14(5):643-54. doi: 10.1002/mabi.201300420. Epub 2014 Jan 21.

PMID:
24446246
35.

Understanding selectin counter-receptor binding from electrostatic energy computations and experimental binding studies.

Woelke AL, Kuehne C, Meyer T, Galstyan G, Dernedde J, Knapp EW.

J Phys Chem B. 2013 Dec 27;117(51):16443-54. doi: 10.1021/jp4099123. Epub 2013 Dec 13.

PMID:
24304345
36.

A facile approach for dual-responsive prodrug nanogels based on dendritic polyglycerols with minimal leaching.

Zhang X, Achazi K, Steinhilber D, Kratz F, Dernedde J, Haag R.

J Control Release. 2014 Jan 28;174:209-16. doi: 10.1016/j.jconrel.2013.11.005. Epub 2013 Nov 10.

PMID:
24225227
37.

Small structural differences of targeted anti-tumor toxins result in strong variation of protein expression.

Gilabert-Oriol R, Thakur M, Weise C, Dernedde J, von Mallinckrodt B, Fuchs H, Weng A.

Protein Expr Purif. 2013 Sep;91(1):54-60. doi: 10.1016/j.pep.2013.07.004. Epub 2013 Jul 16.

PMID:
23867360
38.

Alkyne phosphonites for sequential azide-azide couplings.

Vallée MR, Artner LM, Dernedde J, Hackenberger CP.

Angew Chem Int Ed Engl. 2013 Sep 2;52(36):9504-8. doi: 10.1002/anie.201302462. Epub 2013 Jul 16. No abstract available.

PMID:
23861231
39.

Carbohydrate-PNA and aptamer-PNA conjugates for the spatial screening of lectins and lectin assemblies.

Scheibe C, Wedepohl S, Riese SB, Dernedde J, Seitz O.

Chembiochem. 2013 Jan 21;14(2):236-50. doi: 10.1002/cbic.201200618. Epub 2013 Jan 4.

PMID:
23292704
40.

Multivalency as a chemical organization and action principle.

Fasting C, Schalley CA, Weber M, Seitz O, Hecht S, Koksch B, Dernedde J, Graf C, Knapp EW, Haag R.

Angew Chem Int Ed Engl. 2012 Oct 15;51(42):10472-98. doi: 10.1002/anie.201201114. Epub 2012 Sep 5.

PMID:
22952048
41.

Optical aptasensors for the analysis of the vascular endothelial growth factor (VEGF).

Freeman R, Girsh J, Jou AF, Ho JA, Hug T, Dernedde J, Willner I.

Anal Chem. 2012 Jul 17;84(14):6192-8. doi: 10.1021/ac3011473. Epub 2012 Jul 5.

PMID:
22746189
42.

Chemoselective Staudinger-phosphite reaction of symmetrical glycosyl-phosphites with azido-peptides and polygycerols.

Böhrsch V, Mathew T, Zieringer M, Vallée MR, Artner LM, Dernedde J, Haag R, Hackenberger CP.

Org Biomol Chem. 2012 Aug 14;10(30):6211-6. doi: 10.1039/c2ob25207d. Epub 2012 Jun 12.

PMID:
22688846
43.

Sequence-defined glycopolymer segments presenting mannose: synthesis and lectin binding affinity.

Ponader D, Wojcik F, Beceren-Braun F, Dernedde J, Hartmann L.

Biomacromolecules. 2012 Jun 11;13(6):1845-52. doi: 10.1021/bm300331z. Epub 2012 May 11.

PMID:
22483345
44.

Site-selective modification of proteins for the synthesis of structurally defined multivalent scaffolds.

Artner LM, Merkel L, Bohlke N, Beceren-Braun F, Weise C, Dernedde J, Budisa N, Hackenberger CP.

Chem Commun (Camb). 2012 Jan 14;48(4):522-4. doi: 10.1039/c1cc16039g. Epub 2011 Nov 9.

PMID:
22068135
45.

Multivalent interaction and selectivities in selectin binding of functionalized gold colloids decorated with carbohydrate mimetics.

Roskamp M, Enders S, Pfrengle F, Yekta S, Dekaris V, Dernedde J, Reissig HU, Schlecht S.

Org Biomol Chem. 2011 Nov 7;9(21):7448-56. doi: 10.1039/c1ob05583f. Epub 2011 Sep 9.

PMID:
21904758
46.

SNARE motif-mediated sorting of synaptobrevin by the endocytic adaptors clathrin assembly lymphoid myeloid leukemia (CALM) and AP180 at synapses.

Koo SJ, Markovic S, Puchkov D, Mahrenholz CC, Beceren-Braun F, Maritzen T, Dernedde J, Volkmer R, Oschkinat H, Haucke V.

Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13540-5. doi: 10.1073/pnas.1107067108. Epub 2011 Aug 1.

47.

The role of dimension in multivalent binding events: structure-activity relationship of dendritic polyglycerol sulfate binding to L-selectin in correlation with size and surface charge density.

Weinhart M, Gröger D, Enders S, Riese SB, Dernedde J, Kainthan RK, Brooks DE, Haag R.

Macromol Biosci. 2011 Aug 11;11(8):1088-98. doi: 10.1002/mabi.201100051. Epub 2011 Jun 3.

PMID:
21648090
48.

Synthesis of dendritic polyglycerol anions and their efficiency toward L-selectin inhibition.

Weinhart M, Gröger D, Enders S, Dernedde J, Haag R.

Biomacromolecules. 2011 Jul 11;12(7):2502-11. doi: 10.1021/bm200250f. Epub 2011 May 20.

PMID:
21598905
49.

L-selectin--a dynamic regulator of leukocyte migration.

Wedepohl S, Beceren-Braun F, Riese S, Buscher K, Enders S, Bernhard G, Kilian K, Blanchard V, Dernedde J, Tauber R.

Eur J Cell Biol. 2012 Apr;91(4):257-64. doi: 10.1016/j.ejcb.2011.02.007. Epub 2011 May 4. Review.

PMID:
21546114
50.

Multivalent presentation of mannose on hyperbranched polyglycerol and their interaction with concanavalin A lectin.

Papp I, Dernedde J, Enders S, Riese SB, Shiao TC, Roy R, Haag R.

Chembiochem. 2011 May 2;12(7):1075-83. doi: 10.1002/cbic.201000718. Epub 2011 Apr 8.

PMID:
21480454

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