Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 20

1.

Dual TORK/DNA-PK inhibition blocks critical signaling pathways in chronic lymphocytic leukemia.

Thijssen R, Ter Burg J, Garrick B, van Bochove GG, Brown JR, Fernandes SM, Rodríguez MS, Michot JM, Hallek M, Eichhorst B, Reinhardt HC, Bendell J, Derks IA, van Kampen RJ, Hege K, Kersten MJ, Trowe T, Filvaroff EH, Eldering E, Kater AP.

Blood. 2016 Jul 28;128(4):574-83. doi: 10.1182/blood-2016-02-700328. Epub 2016 May 27.

2.

Assessment of p53 and ATM functionality in chronic lymphocytic leukemia by multiplex ligation-dependent probe amplification.

te Raa GD, Moerland PD, Leeksma AC, Derks IA, Yigittop H, Laddach N, Loden-van Straaten M, Navrkalova V, Trbusek M, Luijks DM, Zenz T, Skowronska A, Hoogendoorn M, Stankovic T, van Oers MH, Eldering E, Kater AP.

Cell Death Dis. 2015 Aug 6;6:e1852. doi: 10.1038/cddis.2015.223.

3.

Blimp-1 homolog Hobit identifies effector-type lymphocytes in humans.

Vieira Braga FA, Hertoghs KM, Kragten NA, Doody GM, Barnes NA, Remmerswaal EB, Hsiao CC, Moerland PD, Wouters D, Derks IA, van Stijn A, Demkes M, Hamann J, Eldering E, Nolte MA, Tooze RM, ten Berge IJ, van Gisbergen KP, van Lier RA.

Eur J Immunol. 2015 Oct;45(10):2945-58. doi: 10.1002/eji.201545650. Epub 2015 Sep 7.

4.

Induction of TAp73 by platinum-based compounds to overcome drug resistance in p53 dysfunctional chronic lymphocytic leukemia.

Tonino SH, Mulkens CE, van Laar J, Derks IA, Suo G, Croon-de Boer F, van Oers MH, Eldering E, Wang JY, Kater AP.

Leuk Lymphoma. 2015;56(8):2439-47. doi: 10.3109/10428194.2014.996751. Epub 2015 Jan 21.

5.

The impact of SF3B1 mutations in CLL on the DNA-damage response.

Te Raa GD, Derks IA, Navrkalova V, Skowronska A, Moerland PD, van Laar J, Oldreive C, Monsuur H, Trbusek M, Malcikova J, Lodén M, Geisler CH, Hüllein J, Jethwa A, Zenz T, Pospisilova S, Stankovic T, van Oers MH, Kater AP, Eldering E.

Leukemia. 2015 May;29(5):1133-42. doi: 10.1038/leu.2014.318. Epub 2014 Nov 5.

PMID:
25371178
6.

IL-21 and CD40L signals from autologous T cells can induce antigen-independent proliferation of CLL cells.

Pascutti MF, Jak M, Tromp JM, Derks IA, Remmerswaal EB, Thijssen R, van Attekum MH, van Bochove GG, Luijks DM, Pals ST, van Lier RA, Kater AP, van Oers MH, Eldering E.

Blood. 2013 Oct 24;122(17):3010-9. doi: 10.1182/blood-2012-11-467670. Epub 2013 Sep 6.

7.

BH3-only protein Noxa contributes to apoptotic control of stress-erythropoiesis.

Wensveen FM, Geest CR, Libregts SFWM, Derks IAM, Ekert PG, Labi V, Villunger A, Nolte MA, Eldering E.

Apoptosis. 2013 Nov;18(11):1306-1318. doi: 10.1007/s10495-013-0890-y.

8.

Pro-apoptotic protein Noxa regulates memory T cell population size and protects against lethal immunopathology.

Wensveen FM, Klarenbeek PL, van Gisbergen KP, Pascutti MF, Derks IA, van Schaik BD, Ten Brinke A, de Vries N, Cekinovic D, Jonjic S, van Lier RA, Eldering E.

J Immunol. 2013 Feb 1;190(3):1180-91. doi: 10.4049/jimmunol.1202304. Epub 2012 Dec 31.

9.

Notch controls the magnitude of T helper cell responses by promoting cellular longevity.

Helbig C, Gentek R, Backer RA, de Souza Y, Derks IA, Eldering E, Wagner K, Jankovic D, Gridley T, Moerland PD, Flavell RA, Amsen D.

Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):9041-6. doi: 10.1073/pnas.1206044109. Epub 2012 May 21.

10.

CD70-driven costimulation induces survival or Fas-mediated apoptosis of T cells depending on antigenic load.

Wensveen FM, Unger PP, Kragten NA, Derks IA, ten Brinke A, Arens R, van Lier RA, Eldering E, van Gisbergen KP.

J Immunol. 2012 May 1;188(9):4256-67. doi: 10.4049/jimmunol.1102889. Epub 2012 Mar 26.

11.

BH3-only protein Noxa regulates apoptosis in activated B cells and controls high-affinity antibody formation.

Wensveen FM, Derks IA, van Gisbergen KP, de Bruin AM, Meijers JC, Yigittop H, Nolte MA, Eldering E, van Lier RA.

Blood. 2012 Feb 9;119(6):1440-9. doi: 10.1182/blood-2011-09-378877. Epub 2011 Dec 5.

12.

A novel mutation in CD132 causes X-CID with defective T-cell activation and impaired humoral reactivity.

Kuijpers TW, Baars PA, Aan de Kerk DJ, Jansen MH, Derks IA, Bredius RG, Sanders EA, van der Burg M, Alders M, van Lier RA.

J Allergy Clin Immunol. 2011 Dec;128(6):1360-1363.e4. doi: 10.1016/j.jaci.2011.07.001. Epub 2011 Aug 9. No abstract available.

PMID:
21831415
13.

Apoptosis induced by overall metabolic stress converges on the Bcl-2 family proteins Noxa and Mcl-1.

Wensveen FM, Alves NL, Derks IA, Reedquist KA, Eldering E.

Apoptosis. 2011 Jul;16(7):708-21. doi: 10.1007/s10495-011-0599-8.

14.

Apoptosis threshold set by Noxa and Mcl-1 after T cell activation regulates competitive selection of high-affinity clones.

Wensveen FM, van Gisbergen KP, Derks IA, Gerlach C, Schumacher TN, van Lier RA, Eldering E.

Immunity. 2010 Jun 25;32(6):754-65. doi: 10.1016/j.immuni.2010.06.005.

15.

CD20 deficiency in humans results in impaired T cell-independent antibody responses.

Kuijpers TW, Bende RJ, Baars PA, Grummels A, Derks IA, Dolman KM, Beaumont T, Tedder TF, van Noesel CJ, Eldering E, van Lier RA.

J Clin Invest. 2010 Jan;120(1):214-22. doi: 10.1172/JCI40231. Epub 2009 Dec 21.

16.

Differential regulation of human IL-7 receptor alpha expression by IL-7 and TCR signaling.

Alves NL, van Leeuwen EM, Derks IA, van Lier RA.

J Immunol. 2008 Apr 15;180(8):5201-10.

17.

Crosstalk among Bcl-2 family members in B-CLL: seliciclib acts via the Mcl-1/Noxa axis and gradual exhaustion of Bcl-2 protection.

Hallaert DY, Spijker R, Jak M, Derks IA, Alves NL, Wensveen FM, de Boer JP, de Jong D, Green SR, van Oers MH, Eldering E.

Cell Death Differ. 2007 Nov;14(11):1958-67. Epub 2007 Aug 17.

18.

The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells.

Alves NL, Derks IA, Berk E, Spijker R, van Lier RA, Eldering E.

Immunity. 2006 Jun;24(6):703-16.

19.

Apoptosis via the B cell antigen receptor requires Bax translocation and involves mitochondrial depolarization, cytochrome C release, and caspase-9 activation.

Eldering E, Mackus WJ, Derks IA, Evers LM, Beuling E, Teeling P, Lens SM, van Oers MH, van Lier RA.

Eur J Immunol. 2004 Jul;34(7):1950-60.

20.

Expression profiling via novel multiplex assay allows rapid assessment of gene regulation in defined signalling pathways.

Eldering E, Spek CA, Aberson HL, Grummels A, Derks IA, de Vos AF, McElgunn CJ, Schouten JP.

Nucleic Acids Res. 2003 Dec 1;31(23):e153.

Supplemental Content

Loading ...
Support Center