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Items: 1 to 50 of 382

1.

Determination of Dermal Pharmacokinetics by Microdialysis Sampling in Rats.

Voelkner NMF, Voelkner A, Derendorf H.

Curr Protoc Pharmacol. 2019 Jun;85(1):e58. doi: 10.1002/cpph.58. Epub 2019 Apr 26.

PMID:
31026128
2.

Drug-Drug Interactions: Progress Over the Past Decade and Looking Ahead to the Future.

Derendorf H, von Richter O, Hermann R, Rostami-Hodjegan A.

Clin Pharmacol Ther. 2019 Jun;105(6):1289-1291. doi: 10.1002/cpt.1410. Epub 2019 Apr 12. No abstract available.

PMID:
30977519
3.

Towards precision dosing of vancomycin: a systematic evaluation of pharmacometric models for Bayesian forecasting.

Broeker A, Nardecchia M, Klinker KP, Derendorf H, Day RO, Marriott DJ, Carland JE, Stocker SL, Wicha SG.

Clin Microbiol Infect. 2019 Mar 11. pii: S1198-743X(19)30097-7. doi: 10.1016/j.cmi.2019.02.029. [Epub ahead of print]

PMID:
30872102
4.

Impact of Ethnicity-Specific Hepatic Microsomal Scaling Factor, Liver Weight, and Cytochrome P450 (CYP) 1A2 Content on Physiologically Based Prediction of CYP1A2-Mediated Pharmacokinetics in Young and Elderly Chinese Adults.

Li GF, Zheng QS, Yu Y, Zhong W, Zhou HH, Qiu F, Wang G, Yu G, Derendorf H.

Clin Pharmacokinet. 2019 Jul;58(7):927-941. doi: 10.1007/s40262-019-00737-5.

PMID:
30767128
5.

Gastric-acid-mediated drug-drug interactions with direct-acting antiviral medications for hepatitis C virus infection: clinical relevance and mitigation strategies.

Yu G, Zheng Y, Yu Y, Li GF, Derendorf H.

Drug Discov Today. 2019 Mar;24(3):845-857. doi: 10.1016/j.drudis.2019.01.003. Epub 2019 Jan 12. Review.

PMID:
30648608
6.

Bioanalytical method development and validation for determination of fibroblast growth factor peptide and its application to pharmacokinetic studies.

Prasanchaimontri IO, Chandasana H, Akbar MA, Swarts S, Okuneiff P, Derendorf H.

Eur J Pharm Biopharm. 2019 Feb;135:83-93. doi: 10.1016/j.ejpb.2018.12.011. Epub 2018 Dec 21.

PMID:
30582960
7.

A model-based analysis of pharmacokinetic-pharmacodynamic (PK/PD) indices of avibactam against Pseudomonas aeruginosa.

Sy SKB, Zhuang L, Xia H, Schuck VJ, Nichols WW, Derendorf H.

Clin Microbiol Infect. 2019 Jul;25(7):904.e9-904.e16. doi: 10.1016/j.cmi.2018.10.014. Epub 2018 Oct 28.

PMID:
30394361
8.

Dose optimization of moxifloxacin and linezolid against tuberculosis using mathematical modeling and simulation.

Heinrichs MT, Drusano GL, Brown DL, Maynard MS, Sy SKB, Rand KH, Peloquin CA, Louie A, Derendorf H.

Int J Antimicrob Agents. 2019 Mar;53(3):275-283. doi: 10.1016/j.ijantimicag.2018.10.012. Epub 2018 Oct 29.

PMID:
30385322
9.

Development of clinical pharmacy services in Australia, Austria, Belgium, Bosnia-Herzegovina, Canada, Germany, Japan, Kosovo, Switzerland, the Netherlands, Thailand, USA and correlation with educational standards, level of research, and implemen.

Rose O, Derendorf H, Erzkamp S, Fujita K, Hartl A, Hoti K, Krass I, Obarcanin E, Saevels J, Srimongkon P, Teichert M, Tsuyuki RT.

Int J Clin Pharmacol Ther. 2018 Nov;56(11):518-530. doi: 10.5414/CP203264.

PMID:
30106363
10.

Clinical Pharmacokinetics and Pharmacodynamics of Ceftazidime-Avibactam Combination: A Model-Informed Strategy for its Clinical Development.

Sy SKB, Zhuang L, Sy S, Derendorf H.

Clin Pharmacokinet. 2019 May;58(5):545-564. doi: 10.1007/s40262-018-0705-y. Review.

PMID:
30097887
11.

Simultaneous quantification of cannabinoids tetrahydrocannabinol, cannabidiol and CB1 receptor antagonist in rat plasma: An application to characterize pharmacokinetics after passive cannabis smoke inhalation and co-administration of rimonabant.

Ravula A, Chandasana H, Setlow B, Febo M, Bruijnzeel AW, Derendorf H.

J Pharm Biomed Anal. 2018 Oct 25;160:119-125. doi: 10.1016/j.jpba.2018.07.004. Epub 2018 Jul 19.

PMID:
30077950
12.

Development of apratoxin S10 (Apra S10) as an anti-pancreatic cancer agent and its preliminary evaluation in an orthotopic patient-derived xenograft (PDX) model.

Cai W, Ratnayake R, Gerber MH, Chen QY, Yu Y, Derendorf H, Trevino JG, Luesch H.

Invest New Drugs. 2019 Apr;37(2):364-374. doi: 10.1007/s10637-018-0647-0. Epub 2018 Aug 3.

PMID:
30073464
13.

Quantitative determination of armodafinil in human plasma by liquid chromatography-electrospray mass spectrometry: Application to a clinical study.

Chandasana H, Kast J, Bittman JA, Derendorf H.

Biomed Chromatogr. 2018 Nov;32(11):e4342. doi: 10.1002/bmc.4342. Epub 2018 Aug 7.

PMID:
30003558
14.

Pharmacokinetics and Comprehensive Analysis of the Tissue Distribution of Eravacycline in Rabbits.

Petraitis V, Petraitiene R, Maung BBW, Khan F, Alisauskaite I, Olesky M, Newman J, Mutlib A, Niu X, Satlin M, Singh RS, Derendorf H, Walsh TJ.

Antimicrob Agents Chemother. 2018 Aug 27;62(9). pii: e00275-18. doi: 10.1128/AAC.00275-18. Print 2018 Sep.

15.

Mycobacterium tuberculosis Strains H37ra and H37rv have equivalent minimum inhibitory concentrations to most antituberculosis drugs.

Heinrichs MT, May RJ, Heider F, Reimers T, B Sy SK, Peloquin CA, Derendorf H.

Int J Mycobacteriol. 2018 Apr-Jun;7(2):156-161. doi: 10.4103/ijmy.ijmy_33_18.

16.

Simultaneous Retrodialysis by Calibrator for Rapid In Vivo Recovery Determination in Target Site Microdialysis.

Yu Y, Chandasana H, Sangari T, Seubert C, Derendorf H.

J Pharm Sci. 2018 Aug;107(8):2259-2265. doi: 10.1016/j.xphs.2018.04.021. Epub 2018 Apr 30.

PMID:
29715477
17.

Restructuring of the Gut Microbiome by Intermittent Fasting Prevents Retinopathy and Prolongs Survival in db/db Mice.

Beli E, Yan Y, Moldovan L, Vieira CP, Gao R, Duan Y, Prasad R, Bhatwadekar A, White FA, Townsend SD, Chan L, Ryan CN, Morton D, Moldovan EG, Chu FI, Oudit GY, Derendorf H, Adorini L, Wang XX, Evans-Molina C, Mirmira RG, Boulton ME, Yoder MC, Li Q, Levi M, Busik JV, Grant MB.

Diabetes. 2018 Sep;67(9):1867-1879. doi: 10.2337/db18-0158. Epub 2018 Apr 30.

18.

Nonlinear Protein Binding: Not What You Think.

Deitchman AN, Singh RSP, Derendorf H.

J Pharm Sci. 2018 Jul;107(7):1754-1760. doi: 10.1016/j.xphs.2018.03.023. Epub 2018 Apr 4. Review.

19.

Quantitative Estimation of Plasma Free Drug Fraction in Patients With Varying Degrees of Hepatic Impairment: A Methodological Evaluation.

Li GF, Yu G, Li Y, Zheng Y, Zheng QS, Derendorf H.

J Pharm Sci. 2018 Jul;107(7):1948-1956. doi: 10.1016/j.xphs.2018.02.021. Epub 2018 Mar 6.

PMID:
29518400
20.

Core Entrustable Professional Activities in Clinical Pharmacology: Pearls for Clinical Practice: Drug-Drug and Food-Drug Interactions.

Hermann R, Derendorf H, von Richter O, Rostami-Hodjegan A.

J Clin Pharmacol. 2018 Jun;58(6):704-716. doi: 10.1002/jcph.1088. Epub 2018 Mar 7. No abstract available.

PMID:
29513896
21.

A comparison of linezolid lung tissue concentrations among patients with drug-resistant tuberculosis.

Kempker RR, Heinrichs MT, Nikolaishvili K, Sabulua I, Bablishvili N, Gogishvili S, Avaliani Z, Little BP, Bernheim A, Derendorf H, Blumberg HM, Vashakidze S, Peloquin CA.

Eur Respir J. 2018 Feb 7;51(2). pii: 1702166. doi: 10.1183/13993003.02166-2017. Print 2018 Feb. No abstract available.

22.

A mathematical model-based analysis of the time-kill kinetics of ceftazidime/avibactam against Pseudomonas aeruginosa.

Sy SKB, Zhuang L, Xia H, Beaudoin ME, Schuck VJ, Nichols WW, Derendorf H.

J Antimicrob Chemother. 2018 May 1;73(5):1295-1304. doi: 10.1093/jac/dkx537.

PMID:
29415212
23.

Enhanced in vitro activity of tigecycline in the presence of chelating agents.

Deitchman AN, Singh RSP, Rand KH, Derendorf H.

Int J Antimicrob Agents. 2018 May;51(5):799-802. doi: 10.1016/j.ijantimicag.2017.12.027. Epub 2018 Jan 3.

24.

Moxifloxacin target site concentrations in patients with pulmonary TB utilizing microdialysis: a clinical pharmacokinetic study.

Heinrichs MT, Vashakidze S, Nikolaishvili K, Sabulua I, Tukvadze N, Bablishvili N, Gogishvili S, Little BP, Bernheim A, Guarner J, Peloquin CA, Blumberg HM, Derendorf H, Kempker RR.

J Antimicrob Chemother. 2018 Feb 1;73(2):477-483. doi: 10.1093/jac/dkx421.

25.

Dermal pharmacokinetics of pyrazinamide determined by microdialysis sampling in rats.

Voelkner NMF, Voelkner A, Costa J, Sy SKB, Hermes J, Weitzel J, Morales S, Derendorf H.

Int J Antimicrob Agents. 2018 Feb;51(2):190-196. doi: 10.1016/j.ijantimicag.2017.10.001. Epub 2017 Oct 13.

PMID:
29032112
26.

Experimental design and modelling approach to evaluate efficacy of β-lactam/β-lactamase inhibitor combinations.

Sy SKB, Derendorf H.

Clin Microbiol Infect. 2018 Jul;24(7):707-715. doi: 10.1016/j.cmi.2017.07.020. Epub 2017 Jul 29.

27.

Drugs in space: Pharmacokinetics and pharmacodynamics in astronauts.

Kast J, Yu Y, Seubert CN, Wotring VE, Derendorf H.

Eur J Pharm Sci. 2017 Nov 15;109S:S2-S8. doi: 10.1016/j.ejps.2017.05.025. Epub 2017 May 19. Review.

PMID:
28533143
28.

Professor Yuichi Sugiyama: A Brilliant, Creative, Amicable, Charming, and Humorous Pharmaceutical Scientist.

Kusuhara H, Obach RS, Rostami-Hodjegan A, Pang KS, Hammarlund-Udenaes M, Derendorf H, Artursson P, Huang SM, Suzuki H, Terasaki T.

J Pharm Sci. 2017 Sep;106(9):2188-2194. doi: 10.1016/j.xphs.2017.04.072. Epub 2017 May 4. No abstract available.

PMID:
28479350
29.

Tissue Distribution of a Therapeutic Monoclonal Antibody Determined by Large Pore Microdialysis.

Jadhav SB, Khaowroongrueng V, Fueth M, Otteneder MB, Richter W, Derendorf H.

J Pharm Sci. 2017 Sep;106(9):2853-2859. doi: 10.1016/j.xphs.2017.03.033. Epub 2017 Apr 13.

PMID:
28414146
30.

Lung Tissue Concentrations of Pyrazinamide among Patients with Drug-Resistant Pulmonary Tuberculosis.

Kempker RR, Heinrichs MT, Nikolaishvili K, Sabulua I, Bablishvili N, Gogishvili S, Avaliani Z, Tukvadze N, Little B, Bernheim A, Read TD, Guarner J, Derendorf H, Peloquin CA, Blumberg HM, Vashakidze S.

Antimicrob Agents Chemother. 2017 May 24;61(6). pii: e00226-17. doi: 10.1128/AAC.00226-17. Print 2017 Jun.

31.

A need to revisit clinical breakpoints of tigecycline: effect of atypical non-linear plasma protein binding.

Singh RSP, Mukker JK, Drescher SK, Deitchman AN, Derendorf H.

Int J Antimicrob Agents. 2017 Apr;49(4):449-455. doi: 10.1016/j.ijantimicag.2016.12.008. Epub 2017 Feb 22.

PMID:
28237830
32.

Prediction of in vivo and in vitro infection model results using a semimechanistic model of avibactam and aztreonam combination against multidrug resistant organisms.

Sy S, Zhuang L, Xia H, Beaudoin ME, Schuck VJ, Derendorf H.

CPT Pharmacometrics Syst Pharmacol. 2017 Mar;6(3):197-207. doi: 10.1002/psp4.12159. Epub 2017 Feb 1.

33.

Potentiation of ceftazidime by avibactam against β-lactam-resistant Pseudomonas aeruginosa in an in vitro infection model.

Sy SK, Zhuang L, Beaudoin ME, Kircher P, Tabosa MA, Cavalcanti NC, Grunwitz C, Pieper S, Schuck VJ, Nichols WW, Derendorf H.

J Antimicrob Chemother. 2017 Apr 1;72(4):1109-1117. doi: 10.1093/jac/dkw535.

PMID:
28077672
34.

Utility of Microdialysis in Infectious Disease Drug Development and Dose Optimization.

Deitchman AN, Heinrichs MT, Khaowroongrueng V, Jadhav SB, Derendorf H.

AAPS J. 2017 Mar;19(2):334-342. doi: 10.1208/s12248-016-0020-1. Epub 2016 Dec 9. Review.

PMID:
27943149
35.

Ceftobiprole medocaril (BAL-5788) for the treatment of complicated skin infections.

Deitchman A, de Jong D, Barbour A, Derendorf H.

Expert Rev Anti Infect Ther. 2016;14(11):997-1006. Epub 2016 Oct 2.

PMID:
27690689
36.

Microdialysis of Large Molecules.

Jadhav SB, Khaowroongrueng V, Derendorf H.

J Pharm Sci. 2016 Nov;105(11):3233-3242. doi: 10.1016/j.xphs.2016.08.016. Epub 2016 Sep 23. Review.

PMID:
27671236
37.

Role of Divalent Metal Ions in Atypical Nonlinear Plasma Protein Binding Behavior of Tigecycline.

Singh RSP, Mukker JK, Deitchman AN, Drescher SK, Derendorf H.

J Pharm Sci. 2016 Nov;105(11):3409-3414. doi: 10.1016/j.xphs.2016.07.013. Epub 2016 Sep 9.

PMID:
27616672
38.

Ciclesonide: A Pro-Soft Drug Approach for Mitigation of Side Effects of Inhaled Corticosteroids.

Mukker JK, Singh RSP, Derendorf H.

J Pharm Sci. 2016 Sep;105(9):2509-2514. doi: 10.1016/j.xphs.2016.05.004. Epub 2016 Jun 21. Review.

PMID:
27339407
39.

Quantitation of the impact of CYP3A5 A6986G polymorphism on quetiapine pharmacokinetics by simulation of target attainment.

Shilbayeh SA, Sy SK, Melhem M, Zmeili R, Derendorf H.

Clin Pharmacol Drug Dev. 2015 Sep;4(5):387-94. doi: 10.1002/cpdd.172. Epub 2015 Jan 12.

PMID:
27137148
40.

In vitro pharmacokinetics/pharmacodynamics of the combination of avibactam and aztreonam against MDR organisms.

Sy SK, Beaudoin ME, Zhuang L, Löblein KI, Lux C, Kissel M, Tremmel R, Frank C, Strasser S, Heuberger JA, Mulder MB, Schuck VJ, Derendorf H.

J Antimicrob Chemother. 2016 Jul;71(7):1866-80. doi: 10.1093/jac/dkw082. Epub 2016 Apr 21.

PMID:
27107096
41.

A Tribute to Dr. Marcus E. Brewster: October 14, 1957-September 15, 2014.

Augustijns P, Loftsson T, Davies M, Derendorf H, Mesens J, Verreck G.

J Pharm Sci. 2016 Sep;105(9):2466-2467. doi: 10.1016/j.xphs.2016.02.001. Epub 2016 Mar 22. No abstract available.

PMID:
27012223
42.

Race-Specific Pharmacodynamic Model of Propofol-Induced Loss of Consciousness.

Lampotang S, Lizdas DE, Derendorf H, Gravenstein N, Lok B, Quarles JP.

J Clin Pharmacol. 2016 Sep;56(9):1141-50. doi: 10.1002/jcph.716. Epub 2016 Mar 28.

43.

Gentamicin dosing strategy in patients with end-stage renal disease receiving haemodialysis: evaluation using a semi-mechanistic pharmacokinetic/pharmacodynamic model.

Zhuang L, He Y, Xia H, Liu Y, Sy SK, Derendorf H.

J Antimicrob Chemother. 2016 Apr;71(4):1012-21. doi: 10.1093/jac/dkv428. Epub 2015 Dec 24.

PMID:
26702923
44.

Pharmacokinetics and pharmacodynamics in antibiotic dose optimization.

Sy SK, Zhuang L, Derendorf H.

Expert Opin Drug Metab Toxicol. 2016;12(1):93-114. doi: 10.1517/17425255.2016.1123250. Epub 2015 Dec 14. Review.

PMID:
26652832
45.

Theory and Application of Microdialysis in Pharmacokinetic Studies.

Zhuang L, Xia H, Gu Y, Derendorf H, Li Y, Liu C.

Curr Drug Metab. 2015;16(10):919-31. Review.

PMID:
26264199
46.

Simultaneous Characterization of Intravenous and Oral Pharmacokinetics of Lychnopholide in Rats by Transit Compartment Model.

Lachi-Silva L, Sy SK, Voelkner A, de Sousa JP, Lopes JL, Silva DB, Lopes NP, Kimura E, Derendorf H, Diniz A.

Planta Med. 2015 Aug;81(12-13):1121-7. doi: 10.1055/s-0035-1546214. Epub 2015 Jul 28.

PMID:
26218336
47.

Enzyme- and transporter-mediated beverage-drug interactions: An update on fruit juices and green tea.

An G, Mukker JK, Derendorf H, Frye RF.

J Clin Pharmacol. 2015 Dec;55(12):1313-31. doi: 10.1002/jcph.563. Epub 2015 Jul 30. Review.

PMID:
26095990
48.

Does the Anesthetic Urethane Influence the Pharmacokinetics of Antifungal Drugs? A Population Pharmacokinetic Investigation in Rats.

Azeredo FJ, Hass SE, Sansone P, Derendorf H, Costa TD, De Araujo BV.

J Pharm Sci. 2015 Oct;104(10):3314-8. doi: 10.1002/jps.24552. Epub 2015 Jun 18.

PMID:
26087701
49.

In memoriam: William A. Craig.

Theuretzbacher U, Ambrose PG, MacGowan AP, Andes DR, Sörgel F, Derendorf H, Mouton JW, Drusano GL, Tulkens PM, Dudley MN, Cars O, Nation RL.

Antimicrob Agents Chemother. 2015;59(6):2971. doi: 10.1128/AAC.00849-15. Epub 2015 Apr 20. No abstract available.

50.

Pharmacokinetic evaluation of avicularin using a model-based development approach.

Buqui GA, Gouvea DR, Sy SK, Voelkner A, Singh RS, da Silva DB, Kimura E, Derendorf H, Lopes NP, Diniz A.

Planta Med. 2015 Mar;81(5):373-81. doi: 10.1055/s-0035-1545728. Epub 2015 Mar 17.

PMID:
25782034

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