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Items: 42


Allogeneic Human Double Negative T Cells as a Novel Immunotherapy for Acute Myeloid Leukemia and Its Underlying Mechanisms.

Lee J, Minden MD, Chen WC, Streck E, Chen B, Kang H, Arruda A, Ly D, Der SD, Kang S, Achita P, D'Souza C, Li Y, Childs RW, Dick JE, Zhang L.

Clin Cancer Res. 2018 Jan 15;24(2):370-382. doi: 10.1158/1078-0432.CCR-17-2228. Epub 2017 Oct 26.


A Cost-Effectiveness Analysis of Using the JBR.10-Based 15-Gene Expression Signature to Guide Adjuvant Chemotherapy in Early Stage Non-Small-Cell Lung Cancer.

Wong KM, Ding K, Li S, Bradbury P, Tsao MS, Der SD, Shepherd FA, Chung C, Ng R, Seymour L, Leighl NB.

Clin Lung Cancer. 2017 Jan;18(1):e41-e47. doi: 10.1016/j.cllc.2016.06.009. Epub 2016 Jul 9.


Appropriateness of using patient-derived xenograft models for pharmacologic evaluation of novel therapies for esophageal/gastro-esophageal junction cancers.

Dodbiba L, Teichman J, Fleet A, Thai H, Starmans MH, Navab R, Chen Z, Girgis H, Eng L, Espin-Garcia O, Shen X, Bandarchi B, Schwock J, Tsao MS, El-Zimaity H, Der SD, Xu W, Bristow RG, Darling GE, Boutros PC, Ailles LE, Liu G.

PLoS One. 2015 Mar 31;10(3):e0121872. doi: 10.1371/journal.pone.0121872. eCollection 2015.


Integrating RAS status into prognostic signatures for adenocarcinomas of the lung.

Starmans MH, Pintilie M, Chan-Seng-Yue M, Moon NC, Haider S, Nguyen F, Lau SK, Liu N, Kasprzyk A, Wouters BG, Der SD, Shepherd FA, Jurisica I, Penn LZ, Tsao MS, Lambin P, Boutros PC.

Clin Cancer Res. 2015 Mar 15;21(6):1477-86. doi: 10.1158/1078-0432.CCR-14-1749. Epub 2015 Jan 21.


Validation of a histology-independent prognostic gene signature for early-stage, non-small-cell lung cancer including stage IA patients.

Der SD, Sykes J, Pintilie M, Zhu CQ, Strumpf D, Liu N, Jurisica I, Shepherd FA, Tsao MS.

J Thorac Oncol. 2014 Jan;9(1):59-64. doi: 10.1097/JTO.0000000000000042.


NKG2D regulates production of soluble TRAIL by ex vivo expanded human γδ T cells.

Dokouhaki P, Schuh NW, Joe B, Allen CA, Der SD, Tsao MS, Zhang L.

Eur J Immunol. 2013 Dec;43(12):3175-82. doi: 10.1002/eji.201243150. Epub 2013 Sep 10.


Exploiting the noise: improving biomarkers with ensembles of data analysis methodologies.

Starmans MH, Pintilie M, John T, Der SD, Shepherd FA, Jurisica I, Lambin P, Tsao MS, Boutros PC.

Genome Med. 2012 Nov 12;4(11):84. doi: 10.1186/gm385. eCollection 2012.


Association of the 15q25 and 5p15 lung cancer susceptibility regions with gene expression in lung tumor tissue.

Fehringer G, Liu G, Pintilie M, Sykes J, Cheng D, Liu N, Chen Z, Seymour L, Der SD, Shepherd FA, Tsao MS, Hung RJ.

Cancer Epidemiol Biomarkers Prev. 2012 Jul;21(7):1097-104. doi: 10.1158/1055-9965.EPI-11-1123-T. Epub 2012 Apr 26.


Re: Gene expression-based prognostic signatures in lung cancer: ready for clinical use?

Boutros PC, Pintilie M, John T, Starmans MH, Der SD, Shepherd FA, Tsao MS, Jurisica I.

J Natl Cancer Inst. 2010 Nov 3;102(21):1677-8; author reply 1678-9. doi: 10.1093/jnci/djq385. Epub 2010 Oct 4. No abstract available.


Silencing of thrombospondin-1 is critical for myc-induced metastatic phenotypes in medulloblastoma.

Zhou L, Picard D, Ra YS, Li M, Northcott PA, Hu Y, Stearns D, Hawkins C, Taylor MD, Rutka J, Der SD, Huang A.

Cancer Res. 2010 Oct 15;70(20):8199-210. doi: 10.1158/0008-5472.CAN-09-4562. Epub 2010 Sep 28.


Oncolytic targeting of renal cell carcinoma via encephalomyocarditis virus.

Roos FC, Roberts AM, Hwang II, Moriyama EH, Evans AJ, Sybingco S, Watson IR, Carneiro LA, Gedye C, Girardin SE, Ailles LE, Jewett MA, Milosevic M, Wilson BC, Bell JC, Der SD, Ohh M.

EMBO Mol Med. 2010 Jul;2(7):275-88. doi: 10.1002/emmm.201000081.


Understanding prognostic gene expression signatures in lung cancer.

Zhu CQ, Pintilie M, John T, Strumpf D, Shepherd FA, Der SD, Jurisica I, Tsao MS.

Clin Lung Cancer. 2009 Sep;10(5):331-40. doi: 10.3816/CLC.2009.n.045. Review.


Prognostic gene signatures for non-small-cell lung cancer.

Boutros PC, Lau SK, Pintilie M, Liu N, Shepherd FA, Der SD, Tsao MS, Penn LZ, Jurisica I.

Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2824-8. doi: 10.1073/pnas.0809444106. Epub 2009 Feb 5.


CD4+ regulatory T cells require CTLA-4 for the maintenance of systemic tolerance.

Friedline RH, Brown DS, Nguyen H, Kornfeld H, Lee J, Zhang Y, Appleby M, Der SD, Kang J, Chambers CA.

J Exp Med. 2009 Feb 16;206(2):421-34. doi: 10.1084/jem.20081811. Epub 2009 Feb 2. Erratum in: J Exp Med. 2009 Mar 16;206(3):721.


Prediction and testing of novel transcriptional networks regulating embryonic stem cell self-renewal and commitment.

Walker E, Ohishi M, Davey RE, Zhang W, Cassar PA, Tanaka TS, Der SD, Morris Q, Hughes TR, Zandstra PW, Stanford WL.

Cell Stem Cell. 2007 Jun 7;1(1):71-86. doi: 10.1016/j.stem.2007.04.002.


Ex vivo transcriptional profiling of human pancreatic islets following chronic exposure to monounsaturated fatty acids.

Bikopoulos G, da Silva Pimenta A, Lee SC, Lakey JR, Der SD, Chan CB, Ceddia RB, Wheeler MB, Rozakis-Adcock M.

J Endocrinol. 2008 Mar;196(3):455-64. doi: 10.1677/JOE-07-0174.


Three-gene prognostic classifier for early-stage non small-cell lung cancer.

Lau SK, Boutros PC, Pintilie M, Blackhall FH, Zhu CQ, Strumpf D, Johnston MR, Darling G, Keshavjee S, Waddell TK, Liu N, Lau D, Penn LZ, Shepherd FA, Jurisica I, Der SD, Tsao MS.

J Clin Oncol. 2007 Dec 10;25(35):5562-9.


The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease.

Rogaeva E, Meng Y, Lee JH, Gu Y, Kawarai T, Zou F, Katayama T, Baldwin CT, Cheng R, Hasegawa H, Chen F, Shibata N, Lunetta KL, Pardossi-Piquard R, Bohm C, Wakutani Y, Cupples LA, Cuenco KT, Green RC, Pinessi L, Rainero I, Sorbi S, Bruni A, Duara R, Friedland RP, Inzelberg R, Hampe W, Bujo H, Song YQ, Andersen OM, Willnow TE, Graff-Radford N, Petersen RC, Dickson D, Der SD, Fraser PE, Schmitt-Ulms G, Younkin S, Mayeux R, Farrer LA, St George-Hyslop P.

Nat Genet. 2007 Feb;39(2):168-77. Epub 2007 Jan 14.


Regulation of gammadelta versus alphabeta T lymphocyte differentiation by the transcription factor SOX13.

Melichar HJ, Narayan K, Der SD, Hiraoka Y, Gardiol N, Jeannet G, Held W, Chambers CA, Kang J.

Science. 2007 Jan 12;315(5809):230-3.


Genomic DNA functions as a universal external standard in quantitative real-time PCR.

Yun JJ, Heisler LE, Hwang II, Wilkins O, Lau SK, Hyrcza M, Jayabalasingham B, Jin J, McLaurin J, Tsao MS, Der SD.

Nucleic Acids Res. 2006 Jul 13;34(12):e85. Erratum in: Nucleic Acids Res. 2006;34(22):6718.


CXCR5/CXCL13 interaction is important for double-negative regulatory T cell homing to cardiac allografts.

Lee BP, Chen W, Shi H, Der SD, Förster R, Zhang L.

J Immunol. 2006 May 1;176(9):5276-83.


Transcriptional regulation of the one-carbon metabolism regulon in Saccharomyces cerevisiae by Bas1p.

Subramanian M, Qiao WB, Khanam N, Wilkins O, Der SD, Lalich JD, Bognar AL.

Mol Microbiol. 2005 Jul;57(1):53-69.


CpG Island microarray probe sequences derived from a physical library are representative of CpG Islands annotated on the human genome.

Heisler LE, Torti D, Boutros PC, Watson J, Chan C, Winegarden N, Takahashi M, Yau P, Huang TH, Farnham PJ, Jurisica I, Woodgett JR, Bremner R, Penn LZ, Der SD.

Nucleic Acids Res. 2005 May 23;33(9):2952-61. Print 2005.


Differentiation of human monocytic cell lines confers susceptibility to Bacillus anthracis lethal toxin.

Kassam A, Der SD, Mogridge J.

Cell Microbiol. 2005 Feb;7(2):281-92.


STAT5 is required for thymopoiesis in a development stage-specific manner.

Kang J, DiBenedetto B, Narayan K, Zhao H, Der SD, Chambers CA.

J Immunol. 2004 Aug 15;173(4):2307-14.


FlaC, a protein of Campylobacter jejuni TGH9011 (ATCC43431) secreted through the flagellar apparatus, binds epithelial cells and influences cell invasion.

Song YC, Jin S, Louie H, Ng D, Lau R, Zhang Y, Weerasekera R, Al Rashid S, Ward LA, Der SD, Chan VL.

Mol Microbiol. 2004 Jul;53(2):541-53.


Microarray gene expression profiling and analysis in renal cell carcinoma.

Liou LS, Shi T, Duan ZH, Sadhukhan P, Der SD, Novick AA, Hissong J, Skacel M, Almasan A, DiDonato JA.

BMC Urol. 2004 Jun 22;4:9.


Cytokine functions in the formative stages of a lymphocyte's life.

Kang J, Der SD.

Curr Opin Immunol. 2004 Apr;16(2):180-90. Review.


Central role of double-stranded RNA-activated protein kinase in microbial induction of nitric oxide synthase.

Uetani K, Der SD, Zamanian-Daryoush M, de La Motte C, Lieberman BY, Williams BR, Erzurum SC.

J Immunol. 2000 Jul 15;165(2):988-96.


Inhibition of double-stranded RNA- and tumor necrosis factor alpha-mediated apoptosis by tetratricopeptide repeat protein and cochaperone P58(IPK).

Tang NM, Korth MJ, Gale M Jr, Wambach M, Der SD, Bandyopadhyay SK, Williams BR, Katze MG.

Mol Cell Biol. 1999 Jul;19(7):4757-65.


Interferon action in triply deficient mice reveals the existence of alternative antiviral pathways.

Zhou A, Paranjape JM, Der SD, Williams BR, Silverman RH.

Virology. 1999 Jun 5;258(2):435-40.


Cell cycle regulation of the double stranded RNA activated protein kinase, PKR.

Zamanian-Daryoush M, Der SD, Williams BR.

Oncogene. 1999 Jan 14;18(2):315-26.


Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays.

Der SD, Zhou A, Williams BR, Silverman RH.

Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15623-8.


A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis.

Der SD, Yang YL, Weissmann C, Williams BR.

Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):3279-83.


Evasion of the interferon-alpha system in HIV infection.

Lau AS, Der SD, Merrill JD, Yeung MC.

Res Immunol. 1994 Oct-Dec;145(8-9):668-73. No abstract available.


Regulation of tumor necrosis factor receptor expression by acid-labile interferon-alpha from AIDS sera.

Lau AS, Der SD, Read SE, Williams BR.

AIDS Res Hum Retroviruses. 1991 Jun;7(6):545-52.


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