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Glucose stimulates somatostatin secretion in pancreatic δ-cells by cAMP-dependent intracellular Ca2+ release.

Denwood G, Tarasov A, Salehi A, Vergari E, Ramracheya R, Takahashi H, Nikolaev VO, Seino S, Gribble F, Reimann F, Rorsman P, Zhang Q.

J Gen Physiol. 2019 Jul 29. pii: jgp.201912351. doi: 10.1085/jgp.201912351. [Epub ahead of print]


Modulation of large dense core vesicle insulin content mediates rhythmic hormone release from pancreatic beta cells over the 24h cycle.

Quinault A, Leloup C, Denwood G, Spiegelhalter C, Rodriguez M, Lefebvre P, Messaddeq N, Zhang Q, Dacquet C, Pénicaud L, Collins SC.

PLoS One. 2018 Mar 15;13(3):e0193882. doi: 10.1371/journal.pone.0193882. eCollection 2018.

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