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Items: 48


Voriconazole enhances UV-induced DNA damage by inhibiting catalase and promoting oxidative stress.

Lee V, Gober MD, Bashir H, O'Day C, Blair IA, Mesaros C, Weng L, Huang A, Chen A, Tang R, Anagnos V, Li J, Roling S, Sagaityte E, Wang A, Lin C, Yeh C, Atillasoy C, Marshall C, Dentchev T, Ridky T, Seykora JT.

Exp Dermatol. 2019 Sep 13. doi: 10.1111/exd.14038. [Epub ahead of print]


Topical kinase inhibitors induce regression of cutaneous squamous cell carcinoma.

Yang X, Daifallah AEM, Shankar S, Beer J, Marshall C, Dentchev T, Seykora F, D'Armas S, Hahn J, Lee V, Sabry HH, Farag AM, Seykora JT.

Exp Dermatol. 2019 May;28(5):609-613. doi: 10.1111/exd.13902. Epub 2019 Mar 13.


Expression of p15 in a spectrum of spitzoid melanocytic neoplasms.

Ma SA, O'Day CP, Dentchev T, Takeshita J, Ridky TW, Seykora JT, Chu EY.

J Cutan Pathol. 2019 May;46(5):310-316. doi: 10.1111/cup.13424. Epub 2019 Feb 14.


Activation of G protein-coupled estrogen receptor signaling inhibits melanoma and improves response to immune checkpoint blockade.

Natale CA, Li J, Zhang J, Dahal A, Dentchev T, Stanger BZ, Ridky TW.

Elife. 2018 Jan 16;7. pii: e31770. doi: 10.7554/eLife.31770.


A pilot study of minocycline for the prevention of paclitaxel-associated neuropathy: ACCRU study RU221408I.

Pachman DR, Dockter T, Zekan PJ, Fruth B, Ruddy KJ, Ta LE, Lafky JM, Dentchev T, Le-Lindqwister NA, Sikov WM, Staff N, Beutler AS, Loprinzi CL.

Support Care Cancer. 2017 Nov;25(11):3407-3416. doi: 10.1007/s00520-017-3760-2. Epub 2017 May 27.


p15 Expression Differentiates Nevus from Melanoma.

Taylor LA, O'Day C, Dentchev T, Hood K, Chu EY, Ridky TW, Seykora JT.

Am J Pathol. 2016 Dec;186(12):3094-3099. doi: 10.1016/j.ajpath.2016.08.009. Epub 2016 Nov 14.


CDKN2B Loss Promotes Progression from Benign Melanocytic Nevus to Melanoma.

McNeal AS, Liu K, Nakhate V, Natale CA, Duperret EK, Capell BC, Dentchev T, Berger SL, Herlyn M, Seykora JT, Ridky TW.

Cancer Discov. 2015 Oct;5(10):1072-85. doi: 10.1158/2159-8290.CD-15-0196. Epub 2015 Jul 16.


Filaggrin-2 barrier protein inversely varies with skin inflammation.

Seykora J, Dentchev T, Margolis DJ.

Exp Dermatol. 2015 Sep;24(9):720-2. doi: 10.1111/exd.12749. Epub 2015 Jul 24. No abstract available.


Rational development and characterization of humanized anti-EGFR variant III chimeric antigen receptor T cells for glioblastoma.

Johnson LA, Scholler J, Ohkuri T, Kosaka A, Patel PR, McGettigan SE, Nace AK, Dentchev T, Thekkat P, Loew A, Boesteanu AC, Cogdill AP, Chen T, Fraietta JA, Kloss CC, Posey AD Jr, Engels B, Singh R, Ezell T, Idamakanti N, Ramones MH, Li N, Zhou L, Plesa G, Seykora JT, Okada H, June CH, Brogdon JL, Maus MV.

Sci Transl Med. 2015 Feb 18;7(275):275ra22. doi: 10.1126/scitranslmed.aaa4963.


Ionizing radiation selectively reduces skin regulatory T cells and alters immune function.

Zhou Y, Ni H, Balint K, Sanzari JK, Dentchev T, Diffenderfer ES, Wilson JM, Cengel KA, Weissman D.

PLoS One. 2014 Jun 24;9(6):e100800. doi: 10.1371/journal.pone.0100800. eCollection 2014.


Comprehensive analysis of gene expression in human retina and supporting tissues.

Li M, Jia C, Kazmierkiewicz KL, Bowman AS, Tian L, Liu Y, Gupta NA, Gudiseva HV, Yee SS, Kim M, Dentchev T, Kimble JA, Parker JS, Messinger JD, Hakonarson H, Curcio CA, Stambolian D.

Hum Mol Genet. 2014 Aug 1;23(15):4001-14. doi: 10.1093/hmg/ddu114. Epub 2014 Mar 14.


CD164 and FCRL3 are highly expressed on CD4+CD26- T cells in S├ęzary syndrome patients.

Wysocka M, Kossenkov AV, Benoit BM, Troxel AB, Singer E, Schaffer A, Kim B, Dentchev T, Nagata S, Ise T, Showe LC, Rook AH.

J Invest Dermatol. 2014 Jan;134(1):229-236. doi: 10.1038/jid.2013.279. Epub 2013 Jun 21.


IL-31 is produced by the malignant T-cell population in cutaneous T-Cell lymphoma and correlates with CTCL pruritus.

Singer EM, Shin DB, Nattkemper LA, Benoit BM, Klein RS, Didigu CA, Loren AW, Dentchev T, Wysocka M, Yosipovitch G, Rook AH.

J Invest Dermatol. 2013 Dec;133(12):2783-2785. doi: 10.1038/jid.2013.227. Epub 2013 May 22. No abstract available.


Viral-associated trichodysplasia: characterization of a novel polyomavirus infection with therapeutic insights.

Wanat KA, Holler PD, Dentchev T, Simbiri K, Robertson E, Seykora JT, Rosenbach M.

Arch Dermatol. 2012 Feb;148(2):219-23. doi: 10.1001/archdermatol.2011.1413.


Intravenous calcium and magnesium for oxaliplatin-induced sensory neurotoxicity in adjuvant colon cancer: NCCTG N04C7.

Grothey A, Nikcevich DA, Sloan JA, Kugler JW, Silberstein PT, Dentchev T, Wender DB, Novotny PJ, Chitaley U, Alberts SR, Loprinzi CL.

J Clin Oncol. 2011 Feb 1;29(4):421-7. doi: 10.1200/JCO.2010.31.5911. Epub 2010 Dec 28.


Alternating systemic and hepatic artery infusion therapy for resected liver metastases from colorectal cancer: a North Central Cancer Treatment Group (NCCTG)/ National Surgical Adjuvant Breast and Bowel Project (NSABP) phase II intergroup trial, N9945/CI-66.

Alberts SR, Roh MS, Mahoney MR, O'Connell MJ, Nagorney DM, Wagman L, Smyrk TC, Weiland TL, Lai LL, Schwarz RE, Molina R, Dentchev T, Bolton JS.

J Clin Oncol. 2010 Feb 10;28(5):853-8. doi: 10.1200/JCO.2009.24.6728. Epub 2010 Jan 4.


Srcasm inhibits Fyn-induced cutaneous carcinogenesis with modulation of Notch1 and p53.

Zhao L, Li W, Marshall C, Griffin T, Hanson M, Hick R, Dentchev T, Williams E, Werth A, Miller C, Bashir H, Pear W, Seykora JT.

Cancer Res. 2009 Dec 15;69(24):9439-47. doi: 10.1158/0008-5472.CAN-09-2976.


North Central Cancer Treatment Group (NCCTG) N0432: phase II trial of docetaxel with capecitabine and bevacizumab as first-line chemotherapy for patients with metastatic breast cancer.

Perez EA, Hillman DW, Dentchev T, Le-Lindqwister NA, Geeraerts LH, Fitch TR, Liu H, Graham DL, Kahanic SP, Gross HM, Patel TA, Palmieri FM, Dueck AC.

Ann Oncol. 2010 Feb;21(2):269-74. doi: 10.1093/annonc/mdp512. Epub 2009 Nov 9.


Osteoporosis prevention in prostate cancer patients receiving androgen ablation therapy: placebo-controlled double-blind study of estradiol and risedronate: N01C8.

Kearns AE, Northfelt DW, Dueck AC, Atherton PJ, Dakhil SR, Rowland KM Jr, Fuloria J, Flynn PJ, Dentchev T, Loprinzi CL.

Support Care Cancer. 2010 Mar;18(3):321-8. doi: 10.1007/s00520-009-0655-x. Epub 2009 May 27.


Immediate versus delayed zoledronic acid for prevention of bone loss in postmenopausal women with breast cancer starting letrozole after tamoxifen-N03CC.

Hines SL, Mincey B, Dentchev T, Sloan JA, Perez EA, Johnson DB, Schaefer PL, Alberts S, Liu H, Kahanic S, Mazurczak MA, Nikcevich DA, Loprinzi CL.

Breast Cancer Res Treat. 2009 Oct;117(3):603-9. doi: 10.1007/s10549-009-0332-2. Epub 2009 Feb 12.


Iron chelation protects the retinal pigment epithelial cell line ARPE-19 against cell death triggered by diverse stimuli.

Lukinova N, Iacovelli J, Dentchev T, Wolkow N, Hunter A, Amado D, Ying GS, Sparrow JR, Dunaief JL.

Invest Ophthalmol Vis Sci. 2009 Mar;50(3):1440-7. doi: 10.1167/iovs.08-2545. Epub 2009 Jan 31.


Iron prochelator BSIH protects retinal pigment epithelial cells against cell death induced by hydrogen peroxide.

Charkoudian LK, Dentchev T, Lukinova N, Wolkow N, Dunaief JL, Franz KJ.

J Inorg Biochem. 2008 Dec;102(12):2130-5. doi: 10.1016/j.jinorgbio.2008.08.001. Epub 2008 Aug 24.


MiRNA expression in the eye.

Huang KM, Dentchev T, Stambolian D.

Mamm Genome. 2008 Aug;19(7-8):510-6. doi: 10.1007/s00335-008-9127-8. Epub 2008 Jul 22. Review.


Ceruloplasmin/hephaestin knockout mice model morphologic and molecular features of AMD.

Hadziahmetovic M, Dentchev T, Song Y, Haddad N, He X, Hahn P, Pratico D, Wen R, Harris ZL, Lambris JD, Beard J, Dunaief JL.

Invest Ophthalmol Vis Sci. 2008 Jun;49(6):2728-36. doi: 10.1167/iovs.07-1472. Epub 2008 Mar 7.


Retinal localization and copper-dependent relocalization of the Wilson and Menkes disease proteins.

Krajacic P, Qian Y, Hahn P, Dentchev T, Lukinova N, Dunaief JL.

Invest Ophthalmol Vis Sci. 2006 Jul;47(7):3129-34.


The iron carrier transferrin is upregulated in retinas from patients with age-related macular degeneration.

Chowers I, Wong R, Dentchev T, Farkas RH, Iacovelli J, Gunatilaka TL, Medeiros NE, Presley JB, Campochiaro PA, Curcio CA, Dunaief JL, Zack DJ.

Invest Ophthalmol Vis Sci. 2006 May;47(5):2135-40.


Phase III study of two different dosing schedules of erythropoietin in anemic patients with cancer.

Steensma DP, Molina R, Sloan JA, Nikcevich DA, Schaefer PL, Rowland KM Jr, Dentchev T, Novotny PJ, Tschetter LK, Alberts SR, Hogan TF, Law A, Loprinzi CL.

J Clin Oncol. 2006 Mar 1;24(7):1079-89.


Strong labeling for iron and the iron-handling proteins ferritin and ferroportin in the photoreceptor layer in age-related macular degeneration.

Dentchev T, Hahn P, Dunaief JL.

Arch Ophthalmol. 2005 Dec;123(12):1745-6. No abstract available.


Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration.

Hahn P, Qian Y, Dentchev T, Chen L, Beard J, Harris ZL, Dunaief JL.

Proc Natl Acad Sci U S A. 2004 Sep 21;101(38):13850-5. Epub 2004 Sep 13.


Immunolocalization and regulation of iron handling proteins ferritin and ferroportin in the retina.

Hahn P, Dentchev T, Qian Y, Rouault T, Harris ZL, Dunaief JL.

Mol Vis. 2004 Aug 26;10:598-607.


Increased metallothionein in light damaged mouse retinas.

Chen L, Wu W, Dentchev T, Wong R, Dunaief JL.

Exp Eye Res. 2004 Aug;79(2):287-93.


Light damage induced changes in mouse retinal gene expression.

Chen L, Wu W, Dentchev T, Zeng Y, Wang J, Tsui I, Tobias JW, Bennett J, Baldwin D, Dunaief JL.

Exp Eye Res. 2004 Aug;79(2):239-47.


Attenuated nef DNA vaccine construct induces cellular immune response: role in HIV-1 multiprotein vaccine.

Majumder B, Gray B, McBurney S, Schaefer TM, Dentchev T, Mahalingam S, Reinhart TA, Ayyavoo V.

Immunol Lett. 2003 Oct 31;89(2-3):207-14.


Costimulatory molecule immune enhancement in a plasmid vaccine model is regulated in part through the Ig constant-like domain of CD80/86.

Agadjanyan MG, Chattergoon MA, Holterman MJ, Monzavi-Karbassi B, Kim JJ, Dentchev T, Wilson D, Ayyavoo V, Montaner LJ, Kieber-Emmons T, Sekaly RP, Weiner DB.

J Immunol. 2003 Oct 15;171(8):4311-9.


Amyloid-beta is found in drusen from some age-related macular degeneration retinas, but not in drusen from normal retinas.

Dentchev T, Milam AH, Lee VM, Trojanowski JQ, Dunaief JL.

Mol Vis. 2003 May 14;9:184-90.


Increased expression of ceruloplasmin in the retina following photic injury.

Chen L, Dentchev T, Wong R, Hahn P, Wen R, Bennett J, Dunaief JL.

Mol Vis. 2003 Apr 30;9:151-8.


Protein Phosphatase 1 binds strongly to the retinoblastoma protein but not to p107 or p130 in vitro and in vivo.

Dunaief JL, King A, Esumi N, Eagen M, Dentchev T, Sung CH, Chen S, Zack DJ.

Curr Eye Res. 2002 May;24(5):392-6.


The role of apoptosis in age-related macular degeneration.

Dunaief JL, Dentchev T, Ying GS, Milam AH.

Arch Ophthalmol. 2002 Nov;120(11):1435-42.


Targeted antigen delivery to antigen-presenting cells including dendritic cells by engineered Fas-mediated apoptosis.

Chattergoon MA, Kim JJ, Yang JS, Robinson TM, Lee DJ, Dentchev T, Wilson DM, Ayyavoo V, Weiner DB.

Nat Biotechnol. 2000 Sep;18(9):974-9.


Chemokine gene adjuvants can modulate immune responses induced by DNA vaccines.

Kim JJ, Yang JS, Dentchev T, Dang K, Weiner DB.

J Interferon Cytokine Res. 2000 May;20(5):487-98.


Immunogenicity of a novel DNA vaccine cassette expressing multiple human immunodeficiency virus (HIV-1) accessory genes.

Ayyavoo V, Kudchodkar S, Ramanathan MP, Le P, Muthumani K, Megalai NM, Dentchev T, Santiago-Barrios L, Mrinalini C, Weiner DB.

AIDS. 2000 Jan 7;14(1):1-9.


Macrophage colony-stimulating factor can modulate immune responses and attract dendritic cells in vivo.

Kim JJ, Yang JS, Lee DJ, Wilson DM, Nottingham LK, Morrison L, Tsai A, Oh J, Dang K, Dentchev T, Agadjanyan MG, Sin JI, Chalian AA, Weiner DB.

Hum Gene Ther. 2000 Jan 20;11(2):305-21.


Antigen-specific humoral and cellular immune responses can be modulated in rhesus macaques through the use of IFN-gamma, IL-12, or IL-18 gene adjuvants.

Kim JJ, Nottingham LK, Tsai A, Lee DJ, Maguire HC, Oh J, Dentchev T, Manson KH, Wyand MS, Agadjanyan MG, Ugen KE, Weiner DB.

J Med Primatol. 1999 Aug-Oct;28(4-5):214-23.


CD86 (B7-2) can function to drive MHC-restricted antigen-specific CTL responses in vivo.

Agadjanyan MG, Kim JJ, Trivedi N, Wilson DM, Monzavi-Karbassi B, Morrison LD, Nottingham LK, Dentchev T, Tsai A, Dang K, Chalian AA, Maldonado MA, Williams WV, Weiner DB.

J Immunol. 1999 Mar 15;162(6):3417-27.


Intracellular adhesion molecule-1 modulates beta-chemokines and directly costimulates T cells in vivo.

Kim JJ, Tsai A, Nottingham LK, Morrison L, Cunning DM, Oh J, Lee DJ, Dang K, Dentchev T, Chalian AA, Agadjanyan MG, Weiner DB.

J Clin Invest. 1999 Mar;103(6):869-77.


Cytokine molecular adjuvants modulate immune responses induced by DNA vaccine constructs for HIV-1 and SIV.

Kim JJ, Simbiri KA, Sin JI, Dang K, Oh J, Dentchev T, Lee D, Nottingham LK, Chalian AA, McCallus D, Ciccarelli R, Agadjanyan MG, Weiner DB.

J Interferon Cytokine Res. 1999 Jan;19(1):77-84.


CD8 positive T cells influence antigen-specific immune responses through the expression of chemokines.

Kim JJ, Nottingham LK, Sin JI, Tsai A, Morrison L, Oh J, Dang K, Hu Y, Kazahaya K, Bennett M, Dentchev T, Wilson DM, Chalian AA, Boyer JD, Agadjanyan MG, Weiner DB.

J Clin Invest. 1998 Sep 15;102(6):1112-24.

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