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Integration of the Duke Activity Status Index into preoperative risk evaluation: a multicentre prospective cohort study.

Wijeysundera DN, Beattie WS, Hillis GS, Abbott TEF, Shulman MA, Ackland GL, Mazer CD, Myles PS, Pearse RM, Cuthbertson BH; Measurement of Exercise Tolerance before Surgery Study Investigators, Myles PS, Shulman MA, Wallace S, Farrington C, Thompson B, Ellis M, Borg B, Kerridge RK, Douglas J, Brannan J, Pretto J, Godsall MG, Beauchamp N, Allen S, Kennedy A, Wright E, Malherbe J, Ismail H, Riedel B, Melville A, Sivakumar H, Murmane A, Kenchington K, Kirabiyik Y, Gurunathan U, Stonell C, Brunello K, Steele K, Tronstad O, Masel P, Dent A, Smith E, Bodger A, Abolfathi M, Sivalingam P, Hall A, Painter TW, Macklin S, Elliott A, Carrera AM, Terblanche NCS, Pitt S, Samuels J, Wilde C, Leslie K, MacCormick A, Bramley D, Southcott AM, Grant J, Taylor H, Bates S, Towns M, Tippett A, Marshall F, Mazer CD, Kunasingam J, Yagnik A, Crescini C, Yagnik S, McCartney CJL, Choi S, Somascanthan P, Flores K, Wijeysundera DN, Beattie WS, Karkouti K, Clarke HA, Jerath A, McCluskey SA, Wasowicz M, Granton JT, Day L, Pazmino-Canizares J, Oh P, Belliard R, Lee L, Dobson K, Chan V, Brull R, Ami N, Stanbrook M, Hagen K, Campbell D, Short T, Van Der Westhuizen J, Higgie K, Lindsay H, Jang R, Wong C, Mcallister D, Ali M, Kumar J, Waymouth E, Kim C, Dimech J, Lorimer M, Tai J, Miller R, Sara R, Collingwood A, Olliff S, Gabriel S, Houston H, Dalley P, Hurford S, Hunt A, Andrews L, Navarra L, Jason-Smith A, Thompson H, McMillan N, Back G, Croal BL, Lum M, Martin D, James S, Filipe H, Pinto M, Kynaston S, Pearse RM, Abbott TEF, Phull M, Beilstein C, Bodger P, Everingham K, Hu Y, Niebrzegowska E, Corriea C, Creary T, Januszewska M, Ahmad T, Whalley J, Haslop R, McNeil J, Brown A, MacDonald N, Pakats M, Greaves K, Jhanji S, Raobaikady R, Black E, Rooms M, Lawrence H, Koutra M, Pirie K, Gertsman M, Jack S, Celinski M, Levett D, Edwards M, Salmon K, Bolger C, Loughney L, Seaward L, Collins H, Tyrell B, Tantony N, Golder K, Ackland GL, Stephens RCM, Gallego-Paredes L, Reyes A, Gutierrez Del Arroyo A, Raj A, Lifford R; International and National Coordinators; Central Project Office Operations Committee; CPET Methods Committee; Outcome Adjudication Committee; International Steering Committee.

Br J Anaesth. 2019 Dec 19. pii: S0007-0912(19)30929-8. doi: 10.1016/j.bja.2019.11.025. [Epub ahead of print]


Innate immunity to malaria-The role of monocytes.

Dobbs KR, Crabtree JN, Dent AE.

Immunol Rev. 2020 Jan;293(1):8-24. doi: 10.1111/imr.12830. Epub 2019 Dec 16. Review.


CXCR5+PD-1+ follicular helper CD8 T cells control B cell tolerance.

Chen Y, Yu M, Zheng Y, Fu G, Xin G, Zhu W, Luo L, Burns R, Li QZ, Dent AL, Zhu N, Cui W, Malherbe L, Wen R, Wang D.

Nat Commun. 2019 Sep 27;10(1):4415. doi: 10.1038/s41467-019-12446-5.


Interleukin-13 Is Unlucky for Allergy Sufferers.

Xie MM, Dent AL.

Trends Pharmacol Sci. 2019 Oct;40(10):714-716. doi: 10.1016/ Epub 2019 Sep 5.


Follicular regulatory T cells inhibit the development of granzyme B-expressing follicular helper T cells.

Xie MM, Fang S, Chen Q, Liu H, Wan J, Dent AL.

JCI Insight. 2019 Aug 22;4(16). pii: 128076. doi: 10.1172/jci.insight.128076.


Roles of T Follicular Helper Cells and T Follicular Regulatory Cells in Autoantibody Production in IL-2-Deficient Mice.

Xie MM, Liu H, Corn C, Koh BH, Kaplan MH, Turner MJ, Dent AL.

Immunohorizons. 2019 Jul 12;3(7):306-316. doi: 10.4049/immunohorizons.1900034.


Monitoring the Formation and Reactivity of Organometallic Alkane and Fluoroalkane Complexes with Silanes and Xe Using Time-Resolved X-ray Absorption Fine Structure Spectroscopy.

Bartlett SA, Besley NA, Dent AJ, Diaz-Moreno S, Evans J, Hamilton ML, Hanson-Heine MWD, Horvath R, Manici V, Sun XZ, Towrie M, Wu L, Zhang X, George MW.

J Am Chem Soc. 2019 Jul 24;141(29):11471-11480. doi: 10.1021/jacs.8b13848. Epub 2019 Jul 15.


Physician perspectives on integration of artificial intelligence into diagnostic pathology.

Sarwar S, Dent A, Faust K, Richer M, Djuric U, Van Ommeren R, Diamandis P.

NPJ Digit Med. 2019 Apr 26;2:28. doi: 10.1038/s41746-019-0106-0. eCollection 2019.


Reduced Transplacental Transfer of Antimalarial Antibodies in Kenyan HIV-Exposed Uninfected Infants.

Ray JE, Dobbs KR, Ogolla SO, Daud II, Vulule J, Sumba PO, Rochford R, Dent AE.

Open Forum Infect Dis. 2019 May 20;6(6):ofz237. doi: 10.1093/ofid/ofz237. eCollection 2019 Jun.


BCL6 modulates tissue neutrophil survival and exacerbates pulmonary inflammation following influenza virus infection.

Zhu B, Zhang R, Li C, Jiang L, Xiang M, Ye Z, Kita H, Melnick AM, Dent AL, Sun J.

Proc Natl Acad Sci U S A. 2019 Jun 11;116(24):11888-11893. doi: 10.1073/pnas.1902310116. Epub 2019 May 28.


The Association of Black Cardiologists (ABC) Cardiovascular Implementation Study (CVIS): A Research Registry Integrating Social Determinants to Support Care for Underserved Patients.

Ofili EO, Schanberg LE, Hutchinson B, Sogade F, Fergus I, Duncan P, Hargrove J, Artis A, Onyekwere O, Batchelor W, Williams M, Oduwole A, Onwuanyi A, Ojutalayo F, Cross JA, Seto TB, Okafor H, Pemu P, Immergluck L, Foreman M, Mensah EA, Quarshie A, Mubasher M, Baker A, Ngare A, Dent A, Malouhi M, Tchounwou P, Lee J, Hayes T, Abdelrahim M, Sarpong D, Fernandez-Repollet E, Sodeke SO, Hernandez A, Thomas K, Dennos A, Smith D, Gbadebo D, Ajuluchikwu J, Kong BW, McCollough C, Weiler SR, Natter MD, Mandl KD, Murphy S.

Int J Environ Res Public Health. 2019 May 10;16(9). pii: E1631. doi: 10.3390/ijerph16091631.


The Research Centers in Minority Institutions (RCMI) Translational Research Network: Building and Sustaining Capacity for Multi-Site Basic Biomedical, Clinical and Behavioral Research.

Ofili EO, Tchounwou PB, Fernandez-Repollet E, Yanagihara R, Akintobi TH, Lee JE, Malouhi M, Garner ST Jr, Hayes TT, Baker AR, Dent AL 2nd, Abdelrahim M, Rollins L, Chang SP, Sy A, Hernandez BY, Bullard PL, Noel RJ Jr, Shiramizu B, Hedges JR, Berry MJ, Bond VC, Lima MF, Mokuau N, Kirken RA, Cruz-Correa M, Sarpong DF, Vadgama J, Yates C, Kahn SA, Soliman KF, Perry G, Pezzano M, Luciano CA, Barnett ME, Oyekan A, Kumar D, Norris KC; RCMI Investigators and RTRN Team Members.

Ethn Dis. 2019 Feb 21;29(Suppl 1):135-144. doi: 10.18865/ed.29.S1.135. eCollection 2019.


Low Levels of Human Antibodies to Gametocyte-Infected Erythrocytes Contrasts the PfEMP1-Dominant Response to Asexual Stages in P. falciparum Malaria.

Chan JA, Drew DR, Reiling L, Lisboa-Pinto A, Dinko B, Sutherland CJ, Dent AE, Chelimo K, Kazura JW, Boyle MJ, Beeson JG.

Front Immunol. 2019 Jan 14;9:3126. doi: 10.3389/fimmu.2018.03126. eCollection 2018.


HIV, Cytomegalovirus, and Malaria Infections during Pregnancy Lead to Inflammation and Shifts in Memory B Cell Subsets in Kenyan Neonates.

Yeo KT, Embury P, Anderson T, Mungai P, Malhotra I, King C, Kazura J, Dent A.

J Immunol. 2019 Mar 1;202(5):1465-1478. doi: 10.4049/jimmunol.1801024. Epub 2019 Jan 23.


Interaction between maternally derived antibodies and heterogeneity in exposure combined to determine time-to-first Plasmodium falciparum infection in Kenyan infants.

Reynaldi A, Dent AE, Schlub TE, Ogolla S, Rochford R, Davenport MP.

Malar J. 2019 Jan 22;18(1):19. doi: 10.1186/s12936-019-2657-6.


A water-cooled monochromator for the B16 Test beamline at the Diamond Light Source: capabilities and performance characterization.

Dolbnya IP, Sawhney KJS, Scott SM, Dent AJ, Cibin G, Preece GM, Pedersen UK, Kelly J, Murray P.

J Synchrotron Radiat. 2019 Jan 1;26(Pt 1):253-262. doi: 10.1107/S1600577518014662. Epub 2019 Jan 1.


Post-transcriptional regulation of the Pseudomonas aeruginosa heme assimilation system (Has) fine-tunes extracellular heme sensing.

Dent AT, Mouriño S, Huang W, Wilks A.

J Biol Chem. 2019 Feb 22;294(8):2771-2785. doi: 10.1074/jbc.RA118.006185. Epub 2018 Dec 28.


Metabolic Syndrome Prevalence in Students Attending West Virginia University.

Olfert MD, Dent A, Wattick RA.

J Clin Med. 2018 Nov 27;7(12). pii: E487. doi: 10.3390/jcm7120487.


Unraveling the H2 Promotional Effect on Palladium-Catalyzed CO Oxidation Using a Combination of Temporally and Spatially Resolved Investigations.

Stewart C, Gibson EK, Morgan K, Cibin G, Dent AJ, Hardacre C, Kondratenko EV, Kondratenko VA, McManus C, Rogers S, Stere CE, Chansai S, Wang YC, Haigh SJ, Wells PP, Goguet A.

ACS Catal. 2018 Sep 7;8(9):8255-8262. doi: 10.1021/acscatal.8b01509. Epub 2018 Jul 26.


Levels of circulating follicular helper T cells, T helper 1 cells, and the prognostic significance of soluble form of CD40 ligand on survival in patients with alcoholic cirrhosis.

Hollister K, Kusumanchi P, Ross RA, Chandler K, Oshodi A, Heathers L, Teagarden S, Wang L, Dent AL, Liangpunsakul S.

Liver Res. 2018 Mar;2(1):52-59. doi: 10.1016/j.livres.2018.02.001. Epub 2018 Feb 22.


Phosphatidylinositol transfer proteins regulate megakaryocyte TGF-β1 secretion and hematopoiesis in mice.

Capitano M, Zhao L, Cooper S, Thorsheim C, Suzuki A, Huang X, Dent AL, Marks MS, Abrams CS, Broxmeyer HE.

Blood. 2018 Sep 6;132(10):1027-1038. doi: 10.1182/blood-2017-09-806257. Epub 2018 Jul 24.


Unexpected Help: Follicular Regulatory T Cells in the Germinal Center.

Xie MM, Dent AL.

Front Immunol. 2018 Jul 2;9:1536. doi: 10.3389/fimmu.2018.01536. eCollection 2018. Review.


Human antibodies activate complement against Plasmodium falciparum sporozoites, and are associated with protection against malaria in children.

Kurtovic L, Behet MC, Feng G, Reiling L, Chelimo K, Dent AE, Mueller I, Kazura JW, Sauerwein RW, Fowkes FJI, Beeson JG.

BMC Med. 2018 Apr 30;16(1):61. doi: 10.1186/s12916-018-1054-2.


Cutting Edge: Plasmodium falciparum Induces Trained Innate Immunity.

Schrum JE, Crabtree JN, Dobbs KR, Kiritsy MC, Reed GW, Gazzinelli RT, Netea MG, Kazura JW, Dent AE, Fitzgerald KA, Golenbock DT.

J Immunol. 2018 Feb 15;200(4):1243-1248. doi: 10.4049/jimmunol.1701010. Epub 2018 Jan 12.


Airway exposure initiates peanut allergy by involving the IL-1 pathway and T follicular helper cells in mice.

Dolence JJ, Kobayashi T, Iijima K, Krempski J, Drake LY, Dent AL, Kita H.

J Allergy Clin Immunol. 2018 Oct;142(4):1144-1158.e8. doi: 10.1016/j.jaci.2017.11.020. Epub 2017 Dec 14.


Sero-catalytic and Antibody Acquisition Models to Estimate Differing Malaria Transmission Intensities in Western Kenya.

Weber GE, White MT, Babakhanyan A, Sumba PO, Vulule J, Ely D, John C, Angov E, Lanar D, Dutta S, Narum DL, Horii T, Cowman A, Beeson J, Smith J, Kazura JW, Dent AE.

Sci Rep. 2017 Dec 4;7(1):16821. doi: 10.1038/s41598-017-17084-9.


Epstein-Barr Virus Type 2 Infects T Cells in Healthy Kenyan Children.

Coleman CB, Daud II, Ogolla SO, Ritchie JA, Smith NA, Sumba PO, Dent AE, Rochford R.

J Infect Dis. 2017 Sep 15;216(6):670-677. doi: 10.1093/infdis/jix363.


Monocyte dysregulation and systemic inflammation during pediatric falciparum malaria.

Dobbs KR, Embury P, Vulule J, Odada PS, Rosa BA, Mitreva M, Kazura JW, Dent AE.

JCI Insight. 2017 Sep 21;2(18). pii: 95352. doi: 10.1172/jci.insight.95352. eCollection 2017 Sep 21.


Bcl6 promotes follicular helper T-cell differentiation and PD-1 expression in a Blimp1-independent manner in mice.

Xie MM, Koh BH, Hollister K, Wu H, Sun J, Kaplan MH, Dent AL.

Eur J Immunol. 2017 Jul;47(7):1136-1141. doi: 10.1002/eji.201747034.


BCL6 represses antiviral resistance in follicular T helper cells.

Amet T, Son YM, Jiang L, Cheon IS, Huang S, Gupta SK, Dent AL, Montaner LJ, Yu Q, Sun J.

J Leukoc Biol. 2017 Aug;102(2):527-536. doi: 10.1189/jlb.4A1216-513RR. Epub 2017 May 26.


Maternal Human Immunodeficiency Virus-Associated Hypergammaglobulinemia Reduces Transplacental Transfer of Immunoglobulin G to Plasmodium falciparum Antigens in Cameroonian Neonates.

Babakhanyan A, Ekali GL, Dent A, Kazura J, Nguasong JT, Fodjo BAY, Yuosembom EK, Esemu LF, Taylor DW, Leke RGF.

Open Forum Infect Dis. 2016 May 10;3(2):ofw092. doi: 10.1093/ofid/ofw092. eCollection 2016 Apr.


Paracrine IL-2 Is Required for Optimal Type 2 Effector Cytokine Production.

Olson MR, Ulrich BJ, Hummel SA, Khan I, Meuris B, Cherukuri Y, Dent AL, Janga SC, Kaplan MH.

J Immunol. 2017 Jun 1;198(11):4352-4359. doi: 10.4049/jimmunol.1601792. Epub 2017 May 3.


IL-21 restricts T follicular regulatory T cell proliferation through Bcl-6 mediated inhibition of responsiveness to IL-2.

Jandl C, Liu SM, Cañete PF, Warren J, Hughes WE, Vogelzang A, Webster K, Craig ME, Uzel G, Dent A, Stepensky P, Keller B, Warnatz K, Sprent J, King C.

Nat Commun. 2017 Mar 17;8:14647. doi: 10.1038/ncomms14647.


Correction: IFN-γ and IL-21 Double Producing T Cells Are Bcl6-Independent and Survive into the Memory Phase in Plasmodium chabaudi Infection.

Carpio VH, Opata MM, Montañez ME, Banerjee PP, Dent AL, Stephens R.

PLoS One. 2017 Mar 10;12(3):e0174048. doi: 10.1371/journal.pone.0174048. eCollection 2017.


A randomized trial examining the effects of Conjoint Behavioral Consultation in rural schools: Student outcomes and the mediating role of the teacher-parent relationship.

Sheridan SM, Witte AL, Holmes SR, Coutts MJ, Dent AL, Kunz GM, Wu C.

J Sch Psychol. 2017 Apr;61:33-53. doi: 10.1016/j.jsp.2016.12.002. Epub 2017 Jan 17.


Molecular epidemiological analysis to assess the influence of pet-ownership in the biodiversity of Staphylococcus aureus and MRSA in dog- and non-dog-owning healthy households.

VAN Balen JC, Landers T, Nutt E, Dent A, Hoet AE.

Epidemiol Infect. 2017 Apr;145(6):1135-1147. doi: 10.1017/S0950268816003228. Epub 2017 Jan 16.


Maternal Vitamin D Status and Adverse Birth Outcomes in Children from Rural Western Kenya.

Toko EN, Sumba OP, Daud II, Ogolla S, Majiwa M, Krisher JT, Ouma C, Dent AE, Rochford R, Mehta S.

Nutrients. 2016 Dec 7;8(12). pii: E794.


AMP kinase promotes Bcl6 expression in both mouse and human T cells.

Xie MM, Amet T, Liu H, Yu Q, Dent AL.

Mol Immunol. 2017 Jan;81:67-75. doi: 10.1016/j.molimm.2016.11.020. Epub 2016 Nov 26.


County-Level Vulnerability Assessment for Rapid Dissemination of HIV or HCV Infections Among Persons Who Inject Drugs, United States.

Van Handel MM, Rose CE, Hallisey EJ, Kolling JL, Zibbell JE, Lewis B, Bohm MK, Jones CM, Flanagan BE, Siddiqi AE, Iqbal K, Dent AL, Mermin JH, McCray E, Ward JW, Brooks JT.

J Acquir Immune Defic Syndr. 2016 Nov 1;73(3):323-331.


A novel approach to identifying patterns of human invasion-inhibitory antibodies guides the design of malaria vaccines incorporating polymorphic antigens.

Drew DR, Wilson DW, Elliott SR, Cross N, Terheggen U, Hodder AN, Siba PM, Chelimo K, Dent AE, Kazura JW, Mueller I, Beeson JG.

BMC Med. 2016 Sep 23;14(1):144.


Correction: IFN-γ and IL-21 Double Producing T Cells Are Bcl6-Independent and Survive into the Memory Phase in Plasmodium chabaudi Infection.

Carpio VH, Opata MM, Montañez ME, Banerjee PP, Dent AL, Stephens R.

PLoS One. 2016 Aug 22;11(8):e0155570. doi: 10.1371/journal.pone.0155570. eCollection 2016.


CXCR5(+) follicular cytotoxic T cells control viral infection in B cell follicles.

Leong YA, Chen Y, Ong HS, Wu D, Man K, Deleage C, Minnich M, Meckiff BJ, Wei Y, Hou Z, Zotos D, Fenix KA, Atnerkar A, Preston S, Chipman JG, Beilman GJ, Allison CC, Sun L, Wang P, Xu J, Toe JG, Lu HK, Tao Y, Palendira U, Dent AL, Landay AL, Pellegrini M, Comerford I, McColl SR, Schacker TW, Long HM, Estes JD, Busslinger M, Belz GT, Lewin SR, Kallies A, Yu D.

Nat Immunol. 2016 Oct;17(10):1187-96. doi: 10.1038/ni.3543. Epub 2016 Aug 3.


Extended-Spectrum β-lactam Resistance in the Enteric Flora of Patients at a Tertiary Care Medical Centre.

Landers TF, Mollenkopf DF, Faubel RL, Dent A, Pancholi P, Daniels JB, Wittum TE.

Zoonoses Public Health. 2017 Mar;64(2):161-164. doi: 10.1111/zph.12293. Epub 2016 Aug 3.


Follicular helper T cells mediate IgE antibody response to airborne allergens.

Kobayashi T, Iijima K, Dent AL, Kita H.

J Allergy Clin Immunol. 2017 Jan;139(1):300-313.e7. doi: 10.1016/j.jaci.2016.04.021. Epub 2016 May 18.


Stat3 Is Important for Follicular Regulatory T Cell Differentiation.

Wu H, Xie MM, Liu H, Dent AL.

PLoS One. 2016 May 5;11(5):e0155040. doi: 10.1371/journal.pone.0155040. eCollection 2016.


STAT3 Impairs STAT5 Activation in the Development of IL-9-Secreting T Cells.

Olson MR, Verdan FF, Hufford MM, Dent AL, Kaplan MH.

J Immunol. 2016 Apr 15;196(8):3297-304. doi: 10.4049/jimmunol.1501801. Epub 2016 Mar 14.


Follicular regulatory T cells repress cytokine production by follicular helper T cells and optimize IgG responses in mice.

Wu H, Chen Y, Liu H, Xu LL, Teuscher P, Wang S, Lu S, Dent AL.

Eur J Immunol. 2016 May;46(5):1152-61. doi: 10.1002/eji.201546094. Epub 2016 Mar 11.


Gut Microbiota Regulates K/BxN Autoimmune Arthritis through Follicular Helper T but Not Th17 Cells.

Block KE, Zheng Z, Dent AL, Kee BL, Huang H.

J Immunol. 2016 Feb 15;196(4):1550-7. doi: 10.4049/jimmunol.1501904. Epub 2016 Jan 18.


Plasmodium malaria and antimalarial antibodies in the first year of life.

Dobbs KR, Dent AE.

Parasitology. 2016 Feb;143(2):129-38. doi: 10.1017/S0031182015001626. Epub 2016 Jan 8. Review.


Contrasting Patterns of Serologic and Functional Antibody Dynamics to Plasmodium falciparum Antigens in a Kenyan Birth Cohort.

Dent AE, Malhotra I, Wang X, Babineau D, Yeo KT, Anderson T, Kimmel RJ, Angov E, Lanar DE, Narum D, Dutta S, Richards J, Beeson JG, Crabb BS, Cowman AF, Horii T, Muchiri E, Mungai PL, King CL, Kazura JW.

Clin Vaccine Immunol. 2015 Dec 9;23(2):104-16. doi: 10.1128/CVI.00452-15. Print 2016 Feb.

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