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Items: 40

1.

Neoadjuvant neratinib promotes ferroptosis and inhibits brain metastasis in a novel syngeneic model of spontaneous HER2+ve breast cancer metastasis.

Nagpal A, Redvers RP, Ling X, Ayton S, Fuentes M, Tavancheh E, Diala I, Lalani A, Loi S, David S, Anderson RL, Smith Y, Merino D, Denoyer D, Pouliot N.

Breast Cancer Res. 2019 Aug 13;21(1):94. doi: 10.1186/s13058-019-1177-1.

2.

Identification of brain metastasis genes and therapeutic evaluation of histone deacetylase inhibitors in a clinically relevant model of breast cancer brain metastasis.

Kim SH, Redvers RP, Chi LH, Ling X, Lucke AJ, Reid RC, Fairlie DP, Martin ACBM, Anderson RL, Denoyer D, Pouliot N.

Dis Model Mech. 2018 Jul 6;11(7). pii: DMM034850. doi: 10.1242/dmm.034850.

3.

Copper accumulation in senescent cells: Interplay between copper transporters and impaired autophagy.

Masaldan S, Clatworthy SAS, Gamell C, Smith ZM, Francis PS, Denoyer D, Meggyesy PM, Fontaine S, Cater MA.

Redox Biol. 2018 Jun;16:322-331. doi: 10.1016/j.redox.2018.03.007. Epub 2018 Mar 17.

4.

Copper Complexes in Cancer Therapy.

Denoyer D, Clatworthy SAS, Cater MA.

Met Ions Life Sci. 2018 Feb 5;18. pii: /books/9783110470734/9783110470734-022/9783110470734-022.xml. doi: 10.1515/9783110470734-022. Review.

PMID:
29394035
5.

[10]-gingerol induces apoptosis and inhibits metastatic dissemination of triple negative breast cancer in vivo.

Martin ACBM, Fuzer AM, Becceneri AB, da Silva JA, Tomasin R, Denoyer D, Kim SH, McIntyre KA, Pearson HB, Yeo B, Nagpal A, Ling X, Selistre-de-Araújo HS, Vieira PC, Cominetti MR, Pouliot N.

Oncotarget. 2017 Aug 10;8(42):72260-72271. doi: 10.18632/oncotarget.20139. eCollection 2017 Sep 22.

6.

Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis.

Masaldan S, Clatworthy SAS, Gamell C, Meggyesy PM, Rigopoulos AT, Haupt S, Haupt Y, Denoyer D, Adlard PA, Bush AI, Cater MA.

Redox Biol. 2018 Apr;14:100-115. doi: 10.1016/j.redox.2017.08.015. Epub 2017 Sep 1.

7.

Sulfonation of Tyrosine as a Method To Improve Biodistribution of Peptide-Based Radiotracers: Novel 18F-Labeled Cyclic RGD Analogues.

Haskali MB, Denoyer D, Noonan W, Culinane C, Rangger C, Pouliot N, Haubner R, Roselt PD, Hicks RJ, Hutton CA.

Mol Pharm. 2017 Apr 3;14(4):1169-1180. doi: 10.1021/acs.molpharmaceut.6b01062. Epub 2017 Feb 28.

PMID:
28191977
8.

Ceruloplasmin is regulated by copper and lactational hormones in PMC42-LA mammary epithelial cell culture models.

Freestone D, Denoyer D, Jakab M, Leigh Ackland M, Cater MA, Michalczyk A.

Metallomics. 2016 Sep 1;8(9):941-50. doi: 10.1039/c6mt00086j. Epub 2016 Jul 18.

PMID:
27426449
9.

Copper as a target for prostate cancer therapeutics: copper-ionophore pharmacology and altering systemic copper distribution.

Denoyer D, Pearson HB, Clatworthy SA, Smith ZM, Francis PS, Llanos RM, Volitakis I, Phillips WA, Meggyesy PM, Masaldan S, Cater MA.

Oncotarget. 2016 Jun 14;7(24):37064-37080. doi: 10.18632/oncotarget.9245.

10.

Targeting copper in cancer therapy: 'Copper That Cancer'.

Denoyer D, Masaldan S, La Fontaine S, Cater MA.

Metallomics. 2015 Nov;7(11):1459-76. doi: 10.1039/c5mt00149h. Epub 2015 Aug 27. Review.

PMID:
26313539
11.

Synthesis and in Vivo Evaluation of [123I]Melanin-Targeted Agents.

Roberts MP, Nguyen V, Ashford ME, Berghofer P, Wyatt NA, Krause-Heuer AM, Pham TQ, Taylor SR, Hogan L, Jiang CD, Fraser BH, Lengkeek NA, Matesic L, Gregoire MC, Denoyer D, Hicks RJ, Katsifis A, Greguric I.

J Med Chem. 2015 Aug 13;58(15):6214-24. doi: 10.1021/acs.jmedchem.5b00777. Epub 2015 Jul 29.

PMID:
26177000
12.

Heterogeneous copper concentrations in cancerous human prostate tissues.

Denoyer D, Clatworthy SA, Masaldan S, Meggyesy PM, Cater MA.

Prostate. 2015 Oct;75(14):1510-7. doi: 10.1002/pros.23022. Epub 2015 May 27.

PMID:
26012532
13.

Analysis of 177Lu-DOTA-octreotate therapy-induced DNA damage in peripheral blood lymphocytes of patients with neuroendocrine tumors.

Denoyer D, Lobachevsky P, Jackson P, Thompson M, Martin OA, Hicks RJ.

J Nucl Med. 2015 Apr;56(4):505-11. doi: 10.2967/jnumed.114.145581. Epub 2015 Feb 26.

14.

Tumour but not stromal expression of β3 integrin is essential, and is required early, for spontaneous dissemination of bone-metastatic breast cancer.

Carter RZ, Micocci KC, Natoli A, Redvers RP, Paquet-Fifield S, Martin AC, Denoyer D, Ling X, Kim SH, Tomasin R, Selistre-de-Araújo H, Anderson RL, Pouliot N.

J Pathol. 2015 Apr;235(5):760-72. doi: 10.1002/path.4490. Epub 2015 Jan 7.

PMID:
25430721
15.

Foxp3 expression in macrophages associated with RENCA tumors in mice.

Devaud C, Yong CS, John LB, Westwood JA, Duong CP, House CM, Denoyer D, Li J, Darcy PK, Kershaw MH.

PLoS One. 2014 Sep 29;9(9):e108670. doi: 10.1371/journal.pone.0108670. eCollection 2014.

16.

Postchemotherapy and tumor-selective targeting with the La-specific DAB4 monoclonal antibody relates to apoptotic cell clearance.

Al-Ejeh F, Staudacher AH, Smyth DR, Darby JM, Denoyer D, Tsopelas C, Hicks RJ, Brown MP.

J Nucl Med. 2014 May;55(5):772-9. doi: 10.2967/jnumed.113.130559. Epub 2014 Mar 27.

17.

Bone-derived soluble factors and laminin-511 cooperate to promote migration, invasion and survival of bone-metastatic breast tumor cells.

Denoyer D, Kusuma N, Burrows A, Ling X, Jupp L, Anderson RL, Pouliot N.

Growth Factors. 2014 Apr;32(2):63-73. doi: 10.3109/08977194.2014.894037. Epub 2014 Mar 6.

PMID:
24601751
18.

PET imaging of tumours with a 64Cu labeled macrobicyclic cage amine ligand tethered to Tyr3-octreotate.

Paterson BM, Roselt P, Denoyer D, Cullinane C, Binns D, Noonan W, Jeffery CM, Price RI, White JM, Hicks RJ, Donnelly PS.

Dalton Trans. 2014 Jan 21;43(3):1386-96. doi: 10.1039/c3dt52647j. Epub 2013 Nov 7.

PMID:
24202174
19.

Enhanced lithium-induced brain recovery following cranial irradiation is not impeded by inflammation.

Malaterre J, McPherson CS, Denoyer D, Lai E, Hagekyriakou J, Lightowler S, Shudo K, Ernst M, Ashley DM, Short JL, Wheeler G, Ramsay RG.

Stem Cells Transl Med. 2012 Jun;1(6):469-79. doi: 10.5966/sctm.2011-0046. Epub 2012 May 30.

20.

Tumour targeting of Auger emitters using DNA ligands conjugated to octreotate.

Lobachevsky P, Smith J, Denoyer D, Skene C, White J, Flynn BL, Kerr DJ, Hicks RJ, Martin RF.

Int J Radiat Biol. 2012 Dec;88(12):1009-18. doi: 10.3109/09553002.2012.666375. Epub 2012 Mar 22.

PMID:
22372657
21.

Preclinical characterization of 18F-D-FPHCys, a new amino acid-based PET tracer.

Denoyer D, Kirby L, Waldeck K, Roselt P, Neels OC, Bourdier T, Shepherd R, Katsifis A, Hicks RJ.

Eur J Nucl Med Mol Imaging. 2012 Apr;39(4):703-12. doi: 10.1007/s00259-011-2017-4. Epub 2011 Dec 13.

PMID:
22160176
22.

Gallium-68 complex of a macrobicyclic cage amine chelator tethered to two integrin-targeting peptides for diagnostic tumor imaging.

Ma MT, Neels OC, Denoyer D, Roselt P, Karas JA, Scanlon DB, White JM, Hicks RJ, Donnelly PS.

Bioconjug Chem. 2011 Oct 19;22(10):2093-103. doi: 10.1021/bc200319q. Epub 2011 Sep 27.

PMID:
21877750
23.

Integrin-dependent response to laminin-511 regulates breast tumor cell invasion and metastasis.

Kusuma N, Denoyer D, Eble JA, Redvers RP, Parker BS, Pelzer R, Anderson RL, Pouliot N.

Int J Cancer. 2012 Feb 1;130(3):555-66. doi: 10.1002/ijc.26018. Epub 2011 May 5.

24.

Radiosynthesis and biological evaluation of L- and D-S-(3-[18F]fluoropropyl)homocysteine for tumor imaging using positron emission tomography.

Bourdier T, Shepherd R, Berghofer P, Jackson T, Fookes CJ, Denoyer D, Dorow DS, Greguric I, Gregoire MC, Hicks RJ, Katsifis A.

J Med Chem. 2011 Mar 24;54(6):1860-70. doi: 10.1021/jm101513q. Epub 2011 Feb 25.

PMID:
21351733
25.

Improved detection of regional melanoma metastasis using 18F-6-fluoro-N-[2-(diethylamino)ethyl] pyridine-3-carboxamide, a melanin-specific PET probe, by perilesional administration.

Denoyer D, Potdevin T, Roselt P, Neels OC, Kirby L, Greguric I, Katsifis A, Dorow DS, Hicks RJ.

J Nucl Med. 2011 Jan;52(1):115-22. doi: 10.2967/jnumed.110.078154. Epub 2010 Dec 13.

26.

High-contrast PET of melanoma using (18)F-MEL050, a selective probe for melanin with predominantly renal clearance.

Denoyer D, Greguric I, Roselt P, Neels OC, Aide N, Taylor SR, Katsifis A, Dorow DS, Hicks RJ.

J Nucl Med. 2010 Mar;51(3):441-7. doi: 10.2967/jnumed.109.070060. Epub 2010 Feb 11.

27.

Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis.

Stagg J, Divisekera U, McLaughlin N, Sharkey J, Pommey S, Denoyer D, Dwyer KM, Smyth MJ.

Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1547-52. doi: 10.1073/pnas.0908801107. Epub 2010 Jan 4.

28.

Discovery of [18F]N-(2-(diethylamino)ethyl)-6-fluoronicotinamide: a melanoma positron emission tomography imaging radiotracer with high tumor to body contrast ratio and rapid renal clearance.

Greguric I, Taylor SR, Denoyer D, Ballantyne P, Berghofer P, Roselt P, Pham TQ, Mattner F, Bourdier T, Neels OC, Dorow DS, Loc'h C, Hicks RJ, Katsifis A.

J Med Chem. 2009 Sep 10;52(17):5299-302. doi: 10.1021/jm9008423.

PMID:
19691348
29.

Development of a high-performance liquid chromatographic method for the determination of a new potent radioiodinated melanoma imaging and therapeutic agent.

Denoyer D, Labarre P, Papon J, Miot-Noirault E, Galmier MJ, Madelmont JC, Chezal JM, Moins N.

J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Nov 15;875(2):411-8. doi: 10.1016/j.jchromb.2008.09.021. Epub 2008 Sep 25.

PMID:
18838313
30.

Spectrum of radiopharmaceuticals in nuclear oncology.

Denoyer D, Perek N, Le Jeune N, Dubois F.

Curr Cancer Drug Targets. 2006 May;6(3):181-96. Review.

PMID:
16712456
31.
32.
33.

Correlation between 99mTc-(V)-DMSA uptake and constitutive level of phosphorylated focal adhesion kinase in an in vitro model of cancer cell lines.

Denoyer D, Perek N, Le Jeune N, Cornillon J, Dubois F.

Eur J Nucl Med Mol Imaging. 2005 Jul;32(7):820-7. Epub 2005 Mar 23.

PMID:
15785954
35.

In vitro and in vivo evaluation of the influence of type III NaPi co-transporter activity during apoptosis on 99mTc-(V)DMSA uptake in the human leukaemic cell line U937.

Denoyer D, Perek N, Jeune NL, Frere D, Sabido O, Clotagatide A, Dubois F.

Eur J Nucl Med Mol Imaging. 2004 Oct;31(10):1421-7. Epub 2004 Jun 16.

PMID:
15205924
36.
37.

Evidence that 99mTc-(V)-DMSA uptake is mediated by NaPi cotransporter type III in tumour cell lines.

Denoyer D, Perek N, Le Jeune N, Frere D, Dubois F.

Eur J Nucl Med Mol Imaging. 2004 Jan;31(1):77-84. Epub 2003 Oct 14.

PMID:
14557898
38.
39.

Modulation of the multidrug resistance of glioma by glutathione levels depletion--interaction with Tc-99M-Sestamibi and Tc-99M-Tetrofosmin.

Perek N, Koumanov F, Denoyer D, Boudard D, Dubois F.

Cancer Biother Radiopharm. 2002 Jun;17(3):291-302.

PMID:
12136521
40.

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