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Items: 37


A Protein E-PilA Fusion Protein Shows Vaccine Potential against Nontypeable Haemophilus influenzae in Mice and Chinchillas.

Ysebaert C, Denoël P, Weynants V, Bakaletz LO, Novotny LA, Godfroid F, Hermand P.

Infect Immun. 2019 Jul 23;87(8). pii: e00345-19. doi: 10.1128/IAI.00345-19. Print 2019 Aug.


Impact of the Innovative Medicines Initiative on vaccine development.

Denoel P, Londoño-Hayes P, Chlebus M, de Azero MR.

Nat Rev Drug Discov. 2018 Nov;17(11):769-770. doi: 10.1038/nrd.2018.72. Epub 2018 Jun 1. No abstract available.


Innovation Partnership for a Roadmap on Vaccines in Europe (IPROVE): A vision for the vaccines of tomorrow.

Medaglini D, De Azero MR, Leroy O, Bietrix F, Denoel P.

Vaccine. 2018 Feb 21;36(9):1136-1145. doi: 10.1016/j.vaccine.2017.11.069. Epub 2018 Feb 1. Review.


Preclinical evaluation of a chemically detoxified pneumolysin as pneumococcal vaccine antigen.

Hermand P, Vandercammen A, Mertens E, Di Paolo E, Verlant V, Denoël P, Godfroid F.

Hum Vaccin Immunother. 2017 Jan 2;13(1):220-228. doi: 10.1080/21645515.2016.1234553. Epub 2016 Oct 21.


Could some geriatric characteristics hinder the prescription of anticoagulants in atrial fibrillation in the elderly?

Denoël P, Vanderstraeten J, Mols P, Pepersack T.

J Aging Res. 2014;2014:693740. doi: 10.1155/2014/693740. Epub 2014 Sep 10.


Role of Pht proteins in attachment of Streptococcus pneumoniae to respiratory epithelial cells.

Kallio A, Sepponen K, Hermand P, Denoël P, Godfroid F, Melin M.

Infect Immun. 2014 Apr;82(4):1683-91. doi: 10.1128/IAI.00699-13. Epub 2014 Feb 3.


Protein antigens increase the protective efficacy of a capsule-based vaccine against Staphylococcus aureus in a rat model of osteomyelitis.

Lattar SM, Noto Llana M, Denoël P, Germain S, Buzzola FR, Lee JC, Sordelli DO.

Infect Immun. 2014 Jan;82(1):83-91. doi: 10.1128/IAI.01050-13. Epub 2013 Oct 14.


A protein-based pneumococcal vaccine protects rhesus macaques from pneumonia after experimental infection with Streptococcus pneumoniae.

Denoël P, Philipp MT, Doyle L, Martin D, Carletti G, Poolman JT.

Vaccine. 2011 Jul 26;29(33):5495-501. doi: 10.1016/j.vaccine.2011.05.051. Epub 2011 May 30.


Induction of Bordetella pertussis-specific immune memory by DTPa vaccines.

Morel S, Denoël P, Godfroid F, Cortvrindt C, Vanderheyde N, Poolman J.

Vaccine. 2011 Apr 18;29(18):3449-55. doi: 10.1016/j.vaccine.2011.02.062. Epub 2011 Mar 5.


Combined protective effects of anti-PhtD and anti-pneumococcal polysaccharides.

Denoël P, Godfroid F, Hermand P, Verlant V, Poolman J.

Vaccine. 2011 Sep 2;29(38):6451-3. doi: 10.1016/j.vaccine.2011.01.085. Epub 2011 Feb 11.


Abrogation of nontypeable Haemophilus influenzae protein D function reduces phosphorylcholine decoration, adherence to airway epithelial cells, and fitness in a chinchilla model of otitis media.

Johnson RW, McGillivary G, Denoël P, Poolman J, Bakaletz LO.

Vaccine. 2011 Feb 1;29(6):1211-21. doi: 10.1016/j.vaccine.2010.12.003. Epub 2010 Dec 16.


Preclinical evaluation of the Pht proteins as potential cross-protective pneumococcal vaccine antigens.

Godfroid F, Hermand P, Verlant V, Denoël P, Poolman JT.

Infect Immun. 2011 Jan;79(1):238-45. doi: 10.1128/IAI.00378-10. Epub 2010 Oct 18.


Genetically modified L3,7 and L2 lipooligosaccharides from Neisseria meningitidis serogroup B confer a broad cross-bactericidal response.

Weynants V, Denoël P, Devos N, Janssens D, Feron C, Goraj K, Momin P, Monnom D, Tans C, Vandercammen A, Wauters F, Poolman JT.

Infect Immun. 2009 May;77(5):2084-93. doi: 10.1128/IAI.01108-08. Epub 2009 Mar 16.


Protective activity of the Bordetella pertussis BrkA autotransporter in the murine lung colonization model.

Marr N, Oliver DC, Laurent V, Poolman J, Denoël P, Fernandez RC.

Vaccine. 2008 Aug 12;26(34):4306-11. doi: 10.1016/j.vaccine.2008.06.017. Epub 2008 Jun 26.


Quality of the Haemophilus influenzae type b (Hib) antibody response induced by diphtheria-tetanus-acellular pertussis/Hib combination vaccines.

Denoël PA, Goldblatt D, de Vleeschauwer I, Jacquet JM, Pichichero ME, Poolman JT.

Clin Vaccine Immunol. 2007 Oct;14(10):1362-9. Epub 2007 Aug 15.


Additive and synergistic bactericidal activity of antibodies directed against minor outer membrane proteins of Neisseria meningitidis.

Weynants VE, Feron CM, Goraj KK, Bos MP, Denoël PA, Verlant VG, Tommassen J, Peak IR, Judd RC, Jennings MP, Poolman JT.

Infect Immun. 2007 Nov;75(11):5434-42. Epub 2007 Jul 30.


Experimental infection of rhesus macaques with Streptococcus pneumoniae: a possible model for vaccine assessment.

Philipp MT, Purcell JE, Martin DS, Buck WR, Plauché GB, Ribka EP, DeNoel P, Hermand P, Leiva LE, Bagby GJ, Nelson S.

J Med Primatol. 2006 Jun;35(3):113-22.


Are vaccination programs and isolate polymorphism linked to pertussis re-emergence?

Godfroid F, Denoël P, Poolman J.

Expert Rev Vaccines. 2005 Oct;4(5):757-78. Review.


Comparison of acellular pertussis vaccines-induced immunity against infection due to Bordetella pertussis variant isolates in a mouse model.

Denoël P, Godfroid F, Guiso N, Hallander H, Poolman J.

Vaccine. 2005 Nov 16;23(46-47):5333-41. Epub 2005 Jul 11.


Diphtheria-tetanus-pertussis (DTP) combination vaccines and evaluation of pertussis immune responses.

Godfroid F, Denoël P, de Grave D, Schuerman L, Poolman J.

Int J Med Microbiol. 2004 Oct;294(5):269-76. Review.


Assessment of the nasopharyngeal bacterial flora of rhesus macaques: moraxella, Neisseria, haemophilus, and other genera.

Bowers LC, Purcell JE, Plauché GB, Denoel PA, Lobet Y, Philipp MT.

J Clin Microbiol. 2002 Nov;40(11):4340-2.


Detection and characterization of pediatric serum antibody to the OMP P5-homologous adhesin of nontypeable Haemophilus influenzae during acute otitis media.

Novotny LA, Pichichero ME, Denoël PA, Neyt C, Vanderschrick S, Dequesne G, Bakaletz LO.

Vaccine. 2002 Oct 4;20(29-30):3590-7.


Developing a nontypeable Haemophilus influenzae (NTHi) vaccine.

Poolman JT, Bakaletz L, Cripps A, Denoel PA, Forsgren A, Kyd J, Lobet Y.

Vaccine. 2000 Dec 8;19 Suppl 1:S108-15. Review.


Structure and function prediction of the Brucella abortus P39 protein by comparative modeling with marginal sequence similarities.

de Fays K, Tibor A, Lambert C, Vinals C, Denoël P, De Bolle X, Wouters J, Letesson JJ, Depiereux E.

Protein Eng. 1999 Mar;12(3):217-23.


Identification of the perosamine synthetase gene of Brucella melitensis 16M and involvement of lipopolysaccharide O side chain in Brucella survival in mice and in macrophages.

Godfroid F, Taminiau B, Danese I, Denoel P, Tibor A, Weynants V, Cloeckaert A, Godfroid J, Letesson JJ.

Infect Immun. 1998 Nov;66(11):5485-93.


Survival of a bacterioferritin deletion mutant of Brucella melitensis 16M in human monocyte-derived macrophages.

Denoel PA, Crawford RM, Zygmunt MS, Tibor A, Weynants VE, Godfroid F, Hoover DL, Letesson JJ.

Infect Immun. 1997 Oct;65(10):4337-40.


Humoral immune responses of Brucella-infected cattle, sheep, and goats to eight purified recombinant Brucella proteins in an indirect enzyme-linked immunosorbent assay.

Letesson JJ, Tibor A, van Eynde G, Wansard V, Weynants V, Denoel P, Saman E.

Clin Diagn Lab Immunol. 1997 Sep;4(5):556-64.


Identification of the major T-cell antigens present in the Brucella melitensis B115 protein preparation, Brucellergene OCB.

Denoel PA, Vo TK, Weynants VE, Tibor A, Gilson D, Zygmunt MS, Limet JN, Letesson JJ.

J Med Microbiol. 1997 Sep;46(9):801-6.


Characterization of smooth lipopolysaccharides and O polysaccharides of Brucella species by competition binding assays with monoclonal antibodies.

Weynants V, Gilson D, Cloeckaert A, Tibor A, Denoel PA, Godfroid F, Limet JN, Letesson JJ.

Infect Immun. 1997 May;65(5):1939-43.


Characterization, occurrence, and molecular cloning of a 39-kilodalton Brucella abortus cytoplasmic protein immunodominant in cattle.

Denoel PA, Vo TK, Tibor A, Weynants VE, Trunde JM, Dubray G, Limet JN, Letesson JJ.

Infect Immun. 1997 Feb;65(2):495-502.


Detection of Yersinia enterocolitica serogroup O:3 by a PCR method.

Weynants V, Jadot V, Denoel PA, Tibor A, Letesson JJ.

J Clin Microbiol. 1996 May;34(5):1224-7.


Infection of cattle with Yersinia enterocolitica O:9 a cause of the false positive serological reactions in bovine brucellosis diagnostic tests.

Weynants V, Tibor A, Denoel PA, Saegerman C, Godfroid J, Thiange P, Letesson JJ.

Vet Microbiol. 1996 Jan;48(1-2):101-12.


Cloning and sequencing of the bacterioferritin gene of Brucella melitensis 16M strain.

Denoel PA, Zygmunt MS, Weynants V, Tibor A, Lichtfouse B, Briffeuil P, Limet JN, Letesson JJ.

FEBS Lett. 1995 Mar 20;361(2-3):238-42.


Molecular cloning, nucleotide sequence, and occurrence of a 16.5-kilodalton outer membrane protein of Brucella abortus with similarity to pal lipoproteins.

Tibor A, Weynants V, Denoel P, Lichtfouse B, De Bolle X, Saman E, Limet JN, Letesson JJ.

Infect Immun. 1994 Sep;62(9):3633-9.

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