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Items: 12


Sch35966 is a potent, selective agonist at the peripheral cannabinoid receptor (CB2) in rodents and primates.

Gonsiorek W, Lunn CA, Fan X, Deno G, Kozlowski J, Hipkin RW.

Br J Pharmacol. 2007 Aug;151(8):1262-71. Epub 2007 Jul 2.


Pharmacological characterization of Sch527123, a potent allosteric CXCR1/CXCR2 antagonist.

Gonsiorek W, Fan X, Hesk D, Fossetta J, Qiu H, Jakway J, Billah M, Dwyer M, Chao J, Deno G, Taveras A, Lundell DJ, Hipkin RW.

J Pharmacol Exp Ther. 2007 Aug;322(2):477-85. Epub 2007 May 11.


A novel, orally active CXCR1/2 receptor antagonist, Sch527123, inhibits neutrophil recruitment, mucus production, and goblet cell hyperplasia in animal models of pulmonary inflammation.

Chapman RW, Minnicozzi M, Celly CS, Phillips JE, Kung TT, Hipkin RW, Fan X, Rindgen D, Deno G, Bond R, Gonsiorek W, Billah MM, Fine JS, Hey JA.

J Pharmacol Exp Ther. 2007 Aug;322(2):486-93. Epub 2007 May 11.


Murine CXCR1 is a functional receptor for GCP-2/CXCL6 and interleukin-8/CXCL8.

Fan X, Patera AC, Pong-Kennedy A, Deno G, Gonsiorek W, Manfra DJ, Vassileva G, Zeng M, Jackson C, Sullivan L, Sharif-Rodriguez W, Opdenakker G, Van Damme J, Hedrick JA, Lundell D, Lira SA, Hipkin RW.

J Biol Chem. 2007 Apr 20;282(16):11658-66. Epub 2006 Dec 29.


Characterization of peripheral human cannabinoid receptor (hCB2) expression and pharmacology using a novel radioligand, [35S]Sch225336.

Gonsiorek W, Hesk D, Chen SC, Kinsley D, Fine JS, Jackson JV, Bober LA, Deno G, Bian H, Fossetta J, Lunn CA, Kozlowski JA, Lavey B, Piwinski J, Narula SK, Lundell DJ, Hipkin RW.

J Biol Chem. 2006 Sep 22;281(38):28143-51. Epub 2006 Jun 5.


Pharmacological characterization of human S1P4 using a novel radioligand, [4,5-3H]-dihydrosphingosine-1-phosphate.

Fossetta J, Deno G, Gonsiorek W, Fan X, Lavey B, Das P, Lunn C, Zavodny PJ, Lundell D, Hipkin RW.

Br J Pharmacol. 2004 Jul;142(5):851-60. Epub 2004 Jun 14.


Cloning and pharmacological characterization of CXCR1 and CXCR2 from Macaca fascicularis.

Hipkin RW, Deno G, Fine J, Sun Y, Wilburn B, Fan X, Gonsiorek W, Wiekowski MT.

J Pharmacol Exp Ther. 2004 Jul;310(1):291-300. Epub 2004 Mar 17.


Impairment of leukocyte trafficking in a murine pleuritis model by IL-4 and IL-10.

Fine JS, Rojas-Triana A, Jackson JV, Engstrom LW, Deno GS, Lundell DJ, Bober LA.

Inflammation. 2003 Aug;27(4):161-74.


Pharmacological analysis of calcium responses mediated by the human A3 adenosine receptor in monocyte-derived dendritic cells and recombinant cells.

Fossetta J, Jackson J, Deno G, Fan X, Du XK, Bober L, Soudé-Bermejo A, de Bouteiller O, Caux C, Lunn C, Lundell D, Palmer RK.

Mol Pharmacol. 2003 Feb;63(2):342-50.


Pharmacological characterization of the chemokine receptor, hCCR1 in a stable transfectant and differentiated HL-60 cells: antagonism of hCCR1 activation by MIP-1beta.

Chou CC, Fine JS, Pugliese-Sivo C, Gonsiorek W, Davies L, Deno G, Petro M, Schwarz M, Zavodny PJ, Hipkin RW.

Br J Pharmacol. 2002 Nov;137(5):663-75.


Macrophage inflammatory protein-3 beta enhances IL-10 production by activated human peripheral blood monocytes and T cells.

Byrnes HD, Kaminski H, Mirza A, Deno G, Lundell D, Fine JS.

J Immunol. 1999 Nov 1;163(9):4715-20.


Integration host factor facilitates repression of the put operon in Salmonella typhimurium.

O'Brien K, Deno G, Ostrovsky de Spicer P, Gardner JF, Maloy SR.

Gene. 1992 Sep 1;118(1):13-9.


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