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Items: 1 to 50 of 52

1.

Describing the dynamic translational science landscape through Core Voucher utilization.

Liclican EL, Filler SG, Kaye J, Denny CT.

J Clin Transl Sci. 2019 Jun 14;3(2-3):105-112. doi: 10.1017/cts.2019.4. eCollection 2019 Jun.

2.

Evaluation of In Vitro Activity of the Class I PI3K Inhibitor Buparlisib (BKM120) in Pediatric Bone and Soft Tissue Sarcomas.

Anderson JL, Park A, Akiyama R, Tap WD, Denny CT, Federman N.

PLoS One. 2015 Sep 24;10(9):e0133610. doi: 10.1371/journal.pone.0133610. eCollection 2015.

3.

ChIP-ping away at EWS/ETS transcription networks.

Denny CT.

Cancer Cell. 2014 Nov 10;26(5):595-6. doi: 10.1016/j.ccell.2014.10.016. Epub 2014 Nov 10.

4.

Phosphoproteomic profiling reveals IL6-mediated paracrine signaling within the Ewing sarcoma family of tumors.

Anderson JL, Titz B, Akiyama R, Komisopoulou E, Park A, Tap WD, Graeber TG, Denny CT.

Mol Cancer Res. 2014 Dec;12(12):1740-54. doi: 10.1158/1541-7786.MCR-14-0159. Epub 2014 Aug 4.

5.

Enhanced growth inhibition of osteosarcoma by cytotoxic polymerized liposomal nanoparticles targeting the alcam cell surface receptor.

Federman N, Chan J, Nagy JO, Landaw EM, McCabe K, Wu AM, Triche T, Kang H, Liu B, Marks JD, Denny CT.

Sarcoma. 2012;2012:126906. Epub 2012 Sep 11.

6.

Pediatric sarcomas: translating molecular pathogenesis of disease to novel therapeutic possibilities.

Anderson JL, Denny CT, Tap WD, Federman N.

Pediatr Res. 2012 Aug;72(2):112-21. Review.

7.

Oncogenic fusion protein EWS/FLI1 down-regulates gene expression by both transcriptional and posttranscriptional mechanisms.

France KA, Anderson JL, Park A, Denny CT.

J Biol Chem. 2011 Jul 1;286(26):22750-7. doi: 10.1074/jbc.M111.225433. Epub 2011 Apr 28.

8.

ABT-869 inhibits the proliferation of Ewing Sarcoma cells and suppresses platelet-derived growth factor receptor beta and c-KIT signaling pathways.

Ikeda AK, Judelson DR, Federman N, Glaser KB, Landaw EM, Denny CT, Sakamoto KM.

Mol Cancer Ther. 2010 Mar;9(3):653-60. doi: 10.1158/1535-7163.MCT-09-0812. Epub 2010 Mar 2.

9.

Targeting liposomes toward novel pediatric anticancer therapeutics.

Federman N, Denny CT.

Pediatr Res. 2010 May;67(5):514-9. doi: 10.1203/PDR.0b013e3181d601c5. Review.

PMID:
20118828
10.

Genetically defined EWS/FLI1 model system suggests mesenchymal origin of Ewing's family tumors.

Potikyan G, France KA, Carlson MR, Dong J, Nelson SF, Denny CT.

Lab Invest. 2008 Dec;88(12):1291-302. doi: 10.1038/labinvest.2008.99. Epub 2008 Oct 6.

11.

EWS/FLI1 regulates tumor angiogenesis in Ewing's sarcoma via suppression of thrombospondins.

Potikyan G, Savene RO, Gaulden JM, France KA, Zhou Z, Kleinerman ES, Lessnick SL, Denny CT.

Cancer Res. 2007 Jul 15;67(14):6675-84.

12.

Multiple aromatic side chains within a disordered structure are critical for transcription and transforming activity of EWS family oncoproteins.

Ng KP, Potikyan G, Savene RO, Denny CT, Uversky VN, Lee KA.

Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):479-84. Epub 2007 Jan 3.

13.

Oncogenic MITF dysregulation in clear cell sarcoma: defining the MiT family of human cancers.

Davis IJ, Kim JJ, Ozsolak F, Widlund HR, Rozenblatt-Rosen O, Granter SR, Du J, Fletcher JA, Denny CT, Lessnick SL, Linehan WM, Kung AL, Fisher DE.

Cancer Cell. 2006 Jun;9(6):473-84.

14.
15.

Functional analysis of the EWS/ETS target gene uridine phosphorylase.

Deneen B, Hamidi H, Denny CT.

Cancer Res. 2003 Jul 15;63(14):4268-74.

16.

PIM3 proto-oncogene kinase is a common transcriptional target of divergent EWS/ETS oncoproteins.

Deneen B, Welford SM, Ho T, Hernandez F, Kurland I, Denny CT.

Mol Cell Biol. 2003 Jun;23(11):3897-908.

17.

Focus on embryonal malignancies.

Maris JM, Denny CT.

Cancer Cell. 2002 Dec;2(6):447-50. Review. No abstract available.

18.
19.

Biology of EWS/ETS fusions in Ewing's family tumors.

Arvand A, Denny CT.

Oncogene. 2001 Sep 10;20(40):5747-54. Review.

20.

DNA binding domain-independent pathways are involved in EWS/FLI1-mediated oncogenesis.

Welford SM, Hebert SP, Deneen B, Arvand A, Denny CT.

J Biol Chem. 2001 Nov 9;276(45):41977-84. Epub 2001 Sep 11.

21.

The COOH-terminal domain of FLI-1 is necessary for full tumorigenesis and transcriptional modulation by EWS/FLI-1.

Arvand A, Welford SM, Teitell MA, Denny CT.

Cancer Res. 2001 Jul 1;61(13):5311-7.

22.

EWS-FLI1, EWS-ERG, and EWS-ETV1 oncoproteins of Ewing tumor family all suppress transcription of transforming growth factor beta type II receptor gene.

Im YH, Kim HT, Lee C, Poulin D, Welford S, Sorensen PH, Denny CT, Kim SJ.

Cancer Res. 2000 Mar 15;60(6):1536-40.

23.

Cross-contamination limits the use of recycled anion exchange resins for preparing plasmid DNA.

Kim AI, Hebert SP, Denny CT.

Biotechniques. 2000 Feb;28(2):298. No abstract available.

24.

EWS/ETS fusion genes induce epithelial and neuroectodermal differentiation in NIH 3T3 fibroblasts.

Teitell MA, Thompson AD, Sorensen PH, Shimada H, Triche TJ, Denny CT.

Lab Invest. 1999 Dec;79(12):1535-43.

PMID:
10616204
25.

Divergent Ewing's sarcoma EWS/ETS fusions confer a common tumorigenic phenotype on NIH3T3 cells.

Thompson AD, Teitell MA, Arvand A, Denny CT.

Oncogene. 1999 Sep 30;18(40):5506-13.

26.

TCL1 oncogene expression in AIDS-related lymphomas and lymphoid tissues.

Teitell M, Damore MA, Sulur GG, Turner DE, Stern MH, Said JW, Denny CT, Wall R.

Proc Natl Acad Sci U S A. 1999 Aug 17;96(17):9809-14.

27.

EWS/FLI1 up regulates mE2-C, a cyclin-selective ubiquitin conjugating enzyme involved in cyclin B destruction.

Arvand A, Bastians H, Welford SM, Thompson AD, Ruderman JV, Denny CT.

Oncogene. 1998 Oct 22;17(16):2039-45.

28.

Ewing's sarcoma--a clinical enigma coming into focus.

Denny CT.

J Pediatr Hematol Oncol. 1998 Sep-Oct;20(5):421-5. Review. No abstract available.

PMID:
9787312
29.

Detection of differentially expressed genes in primary tumor tissues using representational differences analysis coupled to microarray hybridization.

Welford SM, Gregg J, Chen E, Garrison D, Sorensen PH, Denny CT, Nelson SF.

Nucleic Acids Res. 1998 Jun 15;26(12):3059-65.

30.

Characterization of transformation related genes in oral cancer cells.

Chang DD, Park NH, Denny CT, Nelson SF, Pe M.

Oncogene. 1998 Apr 16;16(15):1921-30.

31.

EWS/FLI1-induced manic fringe renders NIH 3T3 cells tumorigenic.

May WA, Arvand A, Thompson AD, Braun BS, Wright M, Denny CT.

Nat Genet. 1997 Dec;17(4):495-7.

PMID:
9398859
32.

Biology of EWS/FLI and related fusion genes in Ewing's sarcoma and primitive neuroectodermal tumor.

May WA, Denny CT.

Curr Top Microbiol Immunol. 1997;220:143-50. Review. No abstract available.

PMID:
9103680
33.

Alternatively spliced exons encode the tissue-specific 5' termini of leukocyte pp52 and stromal cell S37 mRNA isoforms.

Thompson AA, Omori SA, Gilly MJ, May W, Gordon MS, Wood WJ Jr, Miyoshi E, Malone CS, Gimble J, Denny CT, Wall R.

Genomics. 1996 Mar 15;32(3):352-7.

PMID:
8838798
34.

Gene rearrangements in Ewing's sarcoma.

Denny CT.

Cancer Invest. 1996;14(1):83-8. Review. No abstract available.

PMID:
8597892
35.

Identification of target genes for the Ewing's sarcoma EWS/FLI fusion protein by representational difference analysis.

Braun BS, Frieden R, Lessnick SL, May WA, Denny CT.

Mol Cell Biol. 1995 Aug;15(8):4623-30.

36.

A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1.

Jeon IS, Davis JN, Braun BS, Sublett JE, Roussel MF, Denny CT, Shapiro DN.

Oncogene. 1995 Mar 16;10(6):1229-34.

PMID:
7700648
37.

Multiple domains mediate transformation by the Ewing's sarcoma EWS/FLI-1 fusion gene.

Lessnick SL, Braun BS, Denny CT, May WA.

Oncogene. 1995 Feb 2;10(3):423-31.

PMID:
7845667
38.

Chronic myelomonocytic leukemia: Tel-a-kinase what Ets all about.

Sawyers CL, Denny CT.

Cell. 1994 Apr 22;77(2):171-3. Review. No abstract available.

PMID:
8168126
39.

A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERG.

Sorensen PH, Lessnick SL, Lopez-Terrada D, Liu XF, Triche TJ, Denny CT.

Nat Genet. 1994 Feb;6(2):146-51.

PMID:
8162068
40.

The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1.

May WA, Lessnick SL, Braun BS, Klemsz M, Lewis BC, Lunsford LB, Hromas R, Denny CT.

Mol Cell Biol. 1993 Dec;13(12):7393-8.

41.

Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation.

May WA, Gishizky ML, Lessnick SL, Lunsford LB, Lewis BC, Delattre O, Zucman J, Thomas G, Denny CT.

Proc Natl Acad Sci U S A. 1993 Jun 15;90(12):5752-6.

42.

Isolation and chromosomal mapping of the human immunoglobulin-associated B29 gene (IGB).

Wood WJ Jr, Thompson AA, Korenberg J, Chen XN, May W, Wall R, Denny CT.

Genomics. 1993 Apr;16(1):187-92.

PMID:
8486355
43.

Human lymphocyte-specific pp52 gene is a member of a highly conserved dispersed family.

May W, Korenberg JR, Chen XN, Lunsford L, Wood WJ, Thompson A, Wall R, Denny CT.

Genomics. 1993 Mar;15(3):515-20.

PMID:
8468046
44.

Creation of a yeast artificial chromosome fragmentation vector based on lysine-2.

Lewis BC, Shah NP, Braun BS, Denny CT.

Genet Anal Tech Appl. 1992 Jun;9(3):86-90.

PMID:
1476795
45.
46.

Leukemia and the disruption of normal hematopoiesis.

Sawyers CL, Denny CT, Witte ON.

Cell. 1991 Jan 25;64(2):337-50. Review. No abstract available.

PMID:
1988151
47.

Streamlined approach to creating yeast artificial chromosome libraries from specialized cell sources.

Feingold JM, Ogden SD, Denny CT.

Proc Natl Acad Sci U S A. 1990 Nov;87(21):8637-41.

48.

Localization of preferential sites of rearrangement within the BCR gene in Philadelphia chromosome-positive acute lymphoblastic leukemia.

Denny CT, Shah NP, Ogden S, Willman C, McConnell T, Crist W, Carroll A, Witte ON.

Proc Natl Acad Sci U S A. 1989 Jun;86(11):4254-8.

49.

Common mechanism of chromosome inversion in B- and T-cell tumors: relevance to lymphoid development.

Denny CT, Hollis GF, Hecht F, Morgan R, Link MP, Smith SD, Kirsch IR.

Science. 1986 Oct 10;234(4773):197-200.

PMID:
3092355
50.

A chromosome 14 inversion in a T-cell lymphoma is caused by site-specific recombination between immunoglobulin and T-cell receptor loci.

Denny CT, Yoshikai Y, Mak TW, Smith SD, Hollis GF, Kirsch IR.

Nature. 1986 Apr 10-16;320(6062):549-51.

PMID:
3008004

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