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Items: 1 to 50 of 200

1.

Corrigendum to "Progress and remaining challenges in high-throughput volume electron microscopy" [Curr Opin Neurobiol 50 (June 2018) 261-267].

Kornfeld J, Denk W.

Curr Opin Neurobiol. 2019 Apr;55:213. doi: 10.1016/j.conb.2019.05.003. No abstract available.

PMID:
31160001
2.

Full reconstruction of large lobula plate tangential cells in Drosophila from a 3D EM dataset.

Boergens KM, Kapfer C, Helmstaedter M, Denk W, Borst A.

PLoS One. 2018 Nov 28;13(11):e0207828. doi: 10.1371/journal.pone.0207828. eCollection 2018.

3.

High-precision automated reconstruction of neurons with flood-filling networks.

Januszewski M, Kornfeld J, Li PH, Pope A, Blakely T, Lindsey L, Maitin-Shepard J, Tyka M, Denk W, Jain V.

Nat Methods. 2018 Aug;15(8):605-610. doi: 10.1038/s41592-018-0049-4. Epub 2018 Jul 16.

PMID:
30013046
4.

Volume EM Reconstruction of Spinal Cord Reveals Wiring Specificity in Speed-Related Motor Circuits.

Svara FN, Kornfeld J, Denk W, Bollmann JH.

Cell Rep. 2018 Jun 5;23(10):2942-2954. doi: 10.1016/j.celrep.2018.05.023.

5.

Progress and remaining challenges in high-throughput volume electron microscopy.

Kornfeld J, Denk W.

Curr Opin Neurobiol. 2018 Jun;50:261-267. doi: 10.1016/j.conb.2018.04.030. Epub 2018 May 12. Review. Erratum in: Curr Opin Neurobiol. 2019 Apr;55:213.

6.

Single-protein detection in crowded molecular environments in cryo-EM images.

Rickgauer JP, Grigorieff N, Denk W.

Elife. 2017 May 3;6. pii: e25648. doi: 10.7554/eLife.25648.

7.

EM connectomics reveals axonal target variation in a sequence-generating network.

Kornfeld J, Benezra SE, Narayanan RT, Svara F, Egger R, Oberlaender M, Denk W, Long MA.

Elife. 2017 Mar 27;6. pii: e24364. doi: 10.7554/eLife.24364.

8.

High-resolution whole-brain staining for electron microscopic circuit reconstruction.

Mikula S, Denk W.

Nat Methods. 2015 Jun;12(6):541-6. doi: 10.1038/nmeth.3361. Epub 2015 Apr 13.

PMID:
25867849
9.

Space-time wiring specificity supports direction selectivity in the retina.

Kim JS, Greene MJ, Zlateski A, Lee K, Richardson M, Turaga SC, Purcaro M, Balkam M, Robinson A, Behabadi BF, Campos M, Denk W, Seung HS; EyeWirers.

Nature. 2014 May 15;509(7500):331-336. doi: 10.1038/nature13240. Epub 2014 May 4.

10.

Learning to segment neurons with non-local quality measures.

Kroeger T, Mikula S, Denk W, Koethe U, Hamprecht FA.

Med Image Comput Comput Assist Interv. 2013;16(Pt 2):419-27.

PMID:
24579168
11.

Controlling FIB-SBEM slice thickness by monitoring the transmitted ion beam.

Boergens KM, Denk W.

J Microsc. 2013 Dec;252(3):258-62. doi: 10.1111/jmi.12086. Epub 2013 Sep 24.

12.

Miniaturization of two-photon microscopy for imaging in freely moving animals.

Helmchen F, Denk W, Kerr JN.

Cold Spring Harb Protoc. 2013 Oct 1;2013(10):904-13. doi: 10.1101/pdb.top078147.

PMID:
24086055
13.

Connectomic reconstruction of the inner plexiform layer in the mouse retina.

Helmstaedter M, Briggman KL, Turaga SC, Jain V, Seung HS, Denk W.

Nature. 2013 Aug 8;500(7461):168-74. doi: 10.1038/nature12346. Erratum in: Nature. 2014 Oct 16;514(7522):394.

PMID:
23925239
14.

Automated in-chamber specimen coating for serial block-face electron microscopy.

Titze B, Denk W.

J Microsc. 2013 May;250(2):101-110. doi: 10.1111/jmi.12023. Epub 2013 Mar 1.

15.

Low-dosage Maximum-A-Posteriori Focusing and Stigmation.

Binding J, Mikula S, Denk W.

Microsc Microanal. 2013 Feb;19(1):38-55. doi: 10.1017/S1431927612013852.

PMID:
23380003
16.

Staining and embedding the whole mouse brain for electron microscopy.

Mikula S, Binding J, Denk W.

Nat Methods. 2012 Dec;9(12):1198-201. doi: 10.1038/nmeth.2213. Epub 2012 Oct 21.

PMID:
23085613
17.

The Kavli Prize winners. Interview by Darran Yates.

Bargmann C, Denk W, Graybiel A.

Nat Rev Neurosci. 2012 Oct;13(10):670-4. doi: 10.1038/nrn3340. Epub 2012 Aug 30. No abstract available.

PMID:
22931892
18.

3D segmentation of SBFSEM images of neuropil by a graphical model over supervoxel boundaries.

Andres B, Koethe U, Kroeger T, Helmstaedter M, Briggman KL, Denk W, Hamprecht FA.

Med Image Anal. 2012 May;16(4):796-805. doi: 10.1016/j.media.2011.11.004. Epub 2011 Dec 19.

PMID:
22374536
19.

Structural neurobiology: missing link to a mechanistic understanding of neural computation.

Denk W, Briggman KL, Helmstaedter M.

Nat Rev Neurosci. 2012 Feb 22;13(5):351-8. doi: 10.1038/nrn3169. Review.

PMID:
22353782
20.

Neurotechnology: Summa technologiae.

Denk W, Miesenböck G.

Curr Opin Neurobiol. 2012 Feb;22(1):1-2. doi: 10.1016/j.conb.2012.01.004. Epub 2012 Feb 3. No abstract available.

PMID:
22305967
21.

Large-scale automated histology in the pursuit of connectomes.

Kleinfeld D, Bharioke A, Blinder P, Bock DD, Briggman KL, Chklovskii DB, Denk W, Helmstaedter M, Kaufhold JP, Lee WC, Meyer HS, Micheva KD, Oberlaender M, Prohaska S, Reid RC, Smith SJ, Takemura S, Tsai PS, Sakmann B.

J Neurosci. 2011 Nov 9;31(45):16125-38. doi: 10.1523/JNEUROSCI.4077-11.2011. Review.

22.

The big and the small: challenges of imaging the brain's circuits.

Lichtman JW, Denk W.

Science. 2011 Nov 4;334(6056):618-23. doi: 10.1126/science.1209168. Review.

PMID:
22053041
23.

Two-photon calcium imaging of evoked activity from L5 somatosensory neurons in vivo.

Mittmann W, Wallace DJ, Czubayko U, Herb JT, Schaefer AT, Looger LL, Denk W, Kerr JN.

Nat Neurosci. 2011 Jul 10;14(8):1089-93. doi: 10.1038/nn.2879.

PMID:
21743473
24.

High-accuracy neurite reconstruction for high-throughput neuroanatomy.

Helmstaedter M, Briggman KL, Denk W.

Nat Neurosci. 2011 Jul 10;14(8):1081-8. doi: 10.1038/nn.2868.

PMID:
21743472
25.

Wiring specificity in the direction-selectivity circuit of the retina.

Briggman KL, Helmstaedter M, Denk W.

Nature. 2011 Mar 10;471(7337):183-8. doi: 10.1038/nature09818.

PMID:
21390125
26.

Second-harmonic generation imaging of membrane potential with retinal analogues.

Theer P, Denk W, Sheves M, Lewis A, Detwiler PB.

Biophys J. 2011 Jan 5;100(1):232-42. doi: 10.1016/j.bpj.2010.11.021.

27.

High speed optical coherence microscopy with autofocus adjustment and a miniaturized endoscopic imaging probe.

Aguirre AD, Sawinski J, Huang SW, Zhou C, Denk W, Fujimoto JG.

Opt Express. 2010 Mar 1;18(5):4222-39. doi: 10.1364/OE.18.004222.

28.

Rapid axonal sprouting and pruning accompany functional reorganization in primary visual cortex.

Yamahachi H, Marik SA, McManus JN, Denk W, Gilbert CD.

Neuron. 2009 Dec 10;64(5):719-29. doi: 10.1016/j.neuron.2009.11.026.

29.

Convolutional networks can learn to generate affinity graphs for image segmentation.

Turaga SC, Murray JF, Jain V, Roth F, Helmstaedter M, Briggman K, Denk W, Seung HS.

Neural Comput. 2010 Feb;22(2):511-38. doi: 10.1162/neco.2009.10-08-881.

PMID:
19922289
30.

Visually evoked activity in cortical cells imaged in freely moving animals.

Sawinski J, Wallace DJ, Greenberg DS, Grossmann S, Denk W, Kerr JN.

Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19557-62. doi: 10.1073/pnas.0903680106. Epub 2009 Nov 4.

31.

3D structural imaging of the brain with photons and electrons.

Helmstaedter M, Briggman KL, Denk W.

Curr Opin Neurobiol. 2008 Dec;18(6):633-41. doi: 10.1016/j.conb.2009.03.005. Epub 2009 Apr 9. Review.

PMID:
19361979
32.

Single-spike detection in vitro and in vivo with a genetic Ca2+ sensor.

Wallace DJ, Meyer zum Alten Borgloh S, Astori S, Yang Y, Bausen M, Kügler S, Palmer AE, Tsien RY, Sprengel R, Kerr JN, Denk W, Hasan MT.

Nat Methods. 2008 Sep;5(9):797-804. doi: 10.1038/nmeth.1242.

PMID:
19160514
33.

Eyecup scope--optical recordings of light stimulus-evoked fluorescence signals in the retina.

Euler T, Hausselt SE, Margolis DJ, Breuninger T, Castell X, Detwiler PB, Denk W.

Pflugers Arch. 2009 Apr;457(6):1393-414. doi: 10.1007/s00424-008-0603-5. Epub 2008 Nov 21.

34.

Axon tracking in serial block-face scanning electron microscopy.

Jurrus E, Hardy M, Tasdizen T, Fletcher PT, Koshevoy P, Chien CB, Denk W, Whitaker R.

Med Image Anal. 2009 Feb;13(1):180-8. doi: 10.1016/j.media.2008.05.002. Epub 2008 Jun 5.

35.

In vivo two-photon voltage-sensitive dye imaging reveals top-down control of cortical layers 1 and 2 during wakefulness.

Kuhn B, Denk W, Bruno RM.

Proc Natl Acad Sci U S A. 2008 May 27;105(21):7588-93. doi: 10.1073/pnas.0802462105.

36.

Spatiotemporally graded NMDA spike/plateau potentials in basal dendrites of neocortical pyramidal neurons.

Major G, Polsky A, Denk W, Schiller J, Tank DW.

J Neurophysiol. 2008 May;99(5):2584-601. doi: 10.1152/jn.00011.2008. Epub 2008 Mar 12.

37.

Imaging in vivo: watching the brain in action.

Kerr JN, Denk W.

Nat Rev Neurosci. 2008 Mar;9(3):195-205. doi: 10.1038/nrn2338. Review.

PMID:
18270513
38.

The three-dimensional micro- and nanostructure of the aortic medial lamellar unit measured using 3D confocal and electron microscopy imaging.

O'Connell MK, Murthy S, Phan S, Xu C, Buchanan J, Spilker R, Dalman RL, Zarins CK, Denk W, Taylor CA.

Matrix Biol. 2008 Apr;27(3):171-81. doi: 10.1016/j.matbio.2007.10.008. Epub 2007 Nov 13.

39.

Targeted patch-clamp recordings and single-cell electroporation of unlabeled neurons in vivo.

Kitamura K, Judkewitz B, Kano M, Denk W, Häusser M.

Nat Methods. 2008 Jan;5(1):61-7. Epub 2007 Dec 23.

PMID:
18157136
40.

Properties of coherence-gated wavefront sensing.

Rueckel M, Denk W.

J Opt Soc Am A Opt Image Sci Vis. 2007 Nov;24(11):3517-29.

PMID:
17975579
41.

Contour-propagation algorithms for semi-automated reconstruction of neural processes.

Macke JH, Maack N, Gupta R, Denk W, Schölkopf B, Borst A.

J Neurosci Methods. 2008 Jan 30;167(2):349-57. Epub 2007 Aug 10.

PMID:
17870180
42.

A dendrite-autonomous mechanism for direction selectivity in retinal starburst amacrine cells.

Hausselt SE, Euler T, Detwiler PB, Denk W.

PLoS Biol. 2007 Jul;5(7):e185. Epub 2007 Jul 10.

43.

Two-photon targeted patching (TPTP) in vivo.

Komai S, Denk W, Osten P, Brecht M, Margrie TW.

Nat Protoc. 2006;1(2):647-52.

PMID:
17406293
44.

Principles of multiphoton-excitation fluorescence microscopy.

Denk W.

CSH Protoc. 2007 Oct 1;2007:pdb.top23. doi: 10.1101/pdb.top23.

PMID:
21356958
45.

On the fundamental imaging-depth limit in two-photon microscopy.

Theer P, Denk W.

J Opt Soc Am A Opt Image Sci Vis. 2006 Dec;23(12):3139-49.

PMID:
17106469
46.

Adaptive wavefront correction in two-photon microscopy using coherence-gated wavefront sensing.

Rueckel M, Mack-Bucher JA, Denk W.

Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17137-42. Epub 2006 Nov 6.

47.

Towards neural circuit reconstruction with volume electron microscopy techniques.

Briggman KL, Denk W.

Curr Opin Neurobiol. 2006 Oct;16(5):562-70. Epub 2006 Sep 8. Review.

PMID:
16962767
48.

Alpha-herpesvirus infection induces the formation of nuclear actin filaments.

Feierbach B, Piccinotti S, Bisher M, Denk W, Enquist LW.

PLoS Pathog. 2006 Aug;2(8):e85. Erratum in: PLoS Pathog. 2006 Sep;2(9):e103.

49.

Postsynaptic excitability is necessary for strengthening of cortical sensory responses during experience-dependent development.

Komai S, Licznerski P, Cetin A, Waters J, Denk W, Brecht M, Osten P.

Nat Neurosci. 2006 Sep;9(9):1125-33. Epub 2006 Aug 20.

PMID:
16921372
50.

Light-efficient, quantum-limited interferometric wavefront estimation by virtual mode sensing.

Lauterbach MA, Ruckel M, Denk W.

Opt Express. 2006 May 1;14(9):3700-14.

PMID:
19516517

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