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Prevalence of multidrug-resistant organisms in nursing homes in Belgium in 2015.

Latour K, Huang TD, Jans B, Berhin C, Bogaerts P, Noel A, Nonhoff C, Dodémont M, Denis O, Ieven M, Loens K, Schoevaerdts D, Catry B, Glupczynski Y.

PLoS One. 2019 Mar 28;14(3):e0214327. doi: 10.1371/journal.pone.0214327. eCollection 2019.


Helminth-induced IL-4 expands bystander memory CD8+ T cells for early control of viral infection.

Rolot M, Dougall AM, Chetty A, Javaux J, Chen T, Xiao X, Machiels B, Selkirk ME, Maizels RM, Hokke C, Denis O, Brombacher F, Vanderplasschen A, Gillet L, Horsnell WGC, Dewals BG.

Nat Commun. 2018 Oct 30;9(1):4516. doi: 10.1038/s41467-018-06978-5.


Host and microbial factors in kidney transplant recipients with Escherichia coli acute pyelonephritis or asymptomatic bacteriuria: a prospective study using whole-genome sequencing.

Coussement J, Argudín MA, Heinrichs A, Racapé J, de Mendonça R, Nienhaus L, Le Moine A, Roisin S, Dodémont M, Jacobs F, Abramowicz D, Johnston BD, Johnson JR, Denis O.

Nephrol Dial Transplant. 2019 May 1;34(5):878-885. doi: 10.1093/ndt/gfy292.


Allergic Asthma Favors Brucella Growth in the Lungs of Infected Mice.

Machelart A, Potemberg G, Van Maele L, Demars A, Lagneaux M, De Trez C, Sabatel C, Bureau F, De Prins S, Percier P, Denis O, Jurion F, Romano M, Vanderwinden JM, Letesson JJ, Muraille E.

Front Immunol. 2018 Aug 10;9:1856. doi: 10.3389/fimmu.2018.01856. eCollection 2018.


European external quality assessments for identification, molecular typing and characterization of Staphylococcus aureus.

Deplano A, Dodémont M, Denis O, Westh H, Gumpert H, Larsen AR, Larsen J, Kearns A, Pichon B, Layer F, Schulte B, Wolz C, Spiliopoulou I, Brennan G, Empel J, Hryniewicz W, de Lencastre H, Faria NA, Codita I, Sabat AJ, Friedrich AW, Deurenberg RH, Tristan A, Laurent F, Vandenesch F.

J Antimicrob Chemother. 2018 Oct 1;73(10):2662-2666. doi: 10.1093/jac/dky260.


An Outpatient Clinic as a Potential Site of Transmission for an Outbreak of New Delhi Metallo-β-Lactamase-producing Klebsiella pneumoniae Sequence Type 716: A Study Using Whole-genome Sequencing.

Heinrichs A, Argudín MA, De Mendonça R, Deplano A, Roisin S, Dodémont M, Coussement J, Filippin L, Dombrecht J, De Bruyne K, Huang TD, Supply P, Byl B, Glupczynski Y, Denis O.

Clin Infect Dis. 2019 Mar 5;68(6):993-1000. doi: 10.1093/cid/ciy581.


Relationship between mold exposure, specific IgE sensitization, and clinical asthma: A case-control study.

Vincent M, Corazza F, Chasseur C, Bladt S, Romano M, Huygen K, Denis O, Michel O.

Ann Allergy Asthma Immunol. 2018 Sep;121(3):333-339. doi: 10.1016/j.anai.2018.06.016. Epub 2018 Jun 23.


Emergence of livestock-associated MRSA isolated from cystic fibrosis patients: Result of a Belgian national survey.

Dodémont M, Argudín MA, Willekens J, Vanderhelst E, Pierard D, Miendje Deyi VY, Hanssens L, Franckx H, Schelstraete P, Leroux-Roels I, Nonhoff C, Deplano A, Knoop C, Malfroot A, Denis O.

J Cyst Fibros. 2019 Jan;18(1):86-93. doi: 10.1016/j.jcf.2018.04.008. Epub 2018 May 24.


Genetic Diversity among Staphylococcus aureus Isolates Showing Oxacillin and/or Cefoxitin Resistance Not Linked to the Presence of mec Genes.

Argudín MA, Roisin S, Nienhaus L, Dodémont M, de Mendonça R, Nonhoff C, Deplano A, Denis O.

Antimicrob Agents Chemother. 2018 Jun 26;62(7). pii: e00091-18. doi: 10.1128/AAC.00091-18. Print 2018 Jul.


In vitro activity of ceftaroline against clinical Staphylococcus aureus isolates collected during a national survey conducted in Belgian hospitals.

Argudín MA, Dodémont M, Taguemount M, Roisin S, de Mendonça R, Deplano A, Nonhoff C, Denis O.

J Antimicrob Chemother. 2018 Jul 1;73(7):2001. doi: 10.1093/jac/dky140. No abstract available.


STAT6 Mediates Footpad Immunopathology in the Absence of IL-12p40 Following Infection of Susceptible BALB/c Mice With Leishmania major.

Kauffmann F, Meert E, de Jonge K, Elkrim Y, Hanot Mambres D, Denis O, Muraille E, Magez S, De Trez C.

Front Immunol. 2018 Mar 14;9:503. doi: 10.3389/fimmu.2018.00503. eCollection 2018.


CC398 Staphylococcus aureus subpopulations in Belgian patients.

Argudín MA, Deplano A, Vandendriessche S, Dodémont M, Nonhoff C, Denis O, Roisin S.

Eur J Clin Microbiol Infect Dis. 2018 May;37(5):911-916. doi: 10.1007/s10096-018-3205-y. Epub 2018 Feb 15.


Mutations at the Ribosomal S10 Gene in Clinical Strains of Staphylococcus aureus with Reduced Susceptibility to Tigecycline.

Argudín MA, Roisin S, Dodémont M, Nonhoff C, Deplano A, Denis O.

Antimicrob Agents Chemother. 2017 Dec 21;62(1). pii: e01852-17. doi: 10.1128/AAC.01852-17. Print 2018 Jan.


Comparison of Different Phenotypic Approaches To Screen and Detect mecC-Harboring Methicillin-Resistant Staphylococcus aureus.

Kriegeskorte A, Idelevich EA, Schlattmann A, Layer F, Strommenger B, Denis O, Paterson GK, Holmes MA, Werner G, Becker K.

J Clin Microbiol. 2017 Dec 26;56(1). pii: e00826-17. doi: 10.1128/JCM.00826-17. Print 2018 Jan.


Prospective evaluation of a high multiplexing real-time polymerase chain reaction array for the rapid identification and characterization of bacteria causative of nosocomial pneumonia from clinical specimens: a proof-of-concept study.

Roisin S, Huang TD, de Mendonça R, Nonhoff C, Bogaerts P, Hites M, Delaere B, Hamels S, de Longueville F, Glupczynski Y, Denis O.

Eur J Clin Microbiol Infect Dis. 2018 Jan;37(1):109-116. doi: 10.1007/s10096-017-3108-3. Epub 2017 Sep 27.


Multicentre evaluation of the BYG Carba v2.0 test, a simplified electrochemical assay for the rapid laboratory detection of carbapenemase-producing Enterobacteriaceae.

Bogaerts P, Oueslati S, Meunier D, Nonhoff C, Yunus S, Massart M, Denis O, Woodford N, Hopkins KL, Naas T, Dortet L, Huang TD, Glupczynski Y.

Sci Rep. 2017 Aug 30;7(1):9937. doi: 10.1038/s41598-017-09820-y.


Bacteria from Animals as a Pool of Antimicrobial Resistance Genes.

Argudín MA, Deplano A, Meghraoui A, Dodémont M, Heinrichs A, Denis O, Nonhoff C, Roisin S.

Antibiotics (Basel). 2017 Jun 6;6(2). pii: E12. doi: 10.3390/antibiotics6020012. Review.


Acquired resistance to macrolides in Pseudomonas aeruginosa from cystic fibrosis patients.

Mustafa MH, Khandekar S, Tunney MM, Elborn JS, Kahl BC, Denis O, Plésiat P, Traore H, Tulkens PM, Vanderbist F, Van Bambeke F.

Eur Respir J. 2017 May 19;49(5). pii: 1601847. doi: 10.1183/13993003.01847-2016. Print 2017 May.


Investigation of inflammatory and allergic responses to common mold species: Results from in vitro experiments, from a mouse model of asthma, and from a group of asthmatic patients.

Vincent M, Percier P, De Prins S, Huygen K, Potemberg G, Muraille E, Romano M, Michel O, Denis O.

Indoor Air. 2017 Sep;27(5):933-945. doi: 10.1111/ina.12385. Epub 2017 Apr 24.


Performance evaluation of direct fluorescent antibody, Focus Diagnostics Simplexa™ Flu A/B & RSV and multi-parameter customized respiratory Taqman® array card in immunocompromised patients.

Steensels D, Reynders M, Descheemaeker P, Curran MD, Jacobs F, Denis O, Delforge ML, Montesinos I.

J Virol Methods. 2017 Jul;245:61-65. doi: 10.1016/j.jviromet.2017.03.013. Epub 2017 Mar 30.


Clinical case of cfr-positive MRSA CC398 in Belgium.

Paridaens H, Coussement J, Argudín MA, Delaere B, Huang TD, Glupczynski Y, Denis O.

Eur J Clin Microbiol Infect Dis. 2017 Aug;36(8):1527-1529. doi: 10.1007/s10096-017-2953-4. Epub 2017 Mar 24. No abstract available.


High-level resistance to meropenem in clinical isolates of Pseudomonas aeruginosa in the absence of carbapenemases: role of active efflux and porin alterations.

Chalhoub H, Sáenz Y, Rodriguez-Villalobos H, Denis O, Kahl BC, Tulkens PM, Van Bambeke F.

Int J Antimicrob Agents. 2016 Dec;48(6):740-743. doi: 10.1016/j.ijantimicag.2016.09.012. Epub 2016 Oct 19.


Characterisation of Staphylococcus aureus isolates from bloodstream infections, Democratic Republic of the Congo.

Vandendriessche S, De Boeck H, Deplano A, Phoba MF, Lunguya O, Falay D, Dauly N, Verhaegen J, Denis O, Jacobs J.

Eur J Clin Microbiol Infect Dis. 2017 Jul;36(7):1163-1171. doi: 10.1007/s10096-017-2904-0. Epub 2017 Jan 23.


Mechanisms of intrinsic resistance and acquired susceptibility of Pseudomonas aeruginosa isolated from cystic fibrosis patients to temocillin, a revived antibiotic.

Chalhoub H, Pletzer D, Weingart H, Braun Y, Tunney MM, Elborn JS, Rodriguez-Villalobos H, Plésiat P, Kahl BC, Denis O, Winterhalter M, Tulkens PM, Van Bambeke F.

Sci Rep. 2017 Jan 16;7:40208. doi: 10.1038/srep40208.


Development of a Dot-Blot Assay for the Detection of Mould-Specific IgE in the Belgian Population.

Vincent M, Romano M, Corazza F, Huygen K, Michel O, Denis O.

Mycopathologia. 2017 Apr;182(3-4):319-329. doi: 10.1007/s11046-016-0091-7. Epub 2016 Nov 22.


Route of transmission of Staphylococcus aureus.

Denis O.

Lancet Infect Dis. 2017 Feb;17(2):124-125. doi: 10.1016/S1473-3099(16)30512-6. Epub 2016 Nov 16. No abstract available.


Inflammatory Properties and Adjuvant Potential of Synthetic Glycolipids Homologous to Mycolate Esters of the Cell Wall of Mycobacterium tuberculosis.

Tima HG, Al Dulayymi JR, Denis O, Lehebel P, Baols KS, Mohammed MO, L'Homme L, Sahb MM, Potemberg G, Legrand S, Lang R, Beyaert R, Piette J, Baird MS, Huygen K, Romano M.

J Innate Immun. 2017;9(2):162-180. doi: 10.1159/000450955. Epub 2016 Nov 18.


Epidemiology and mortality of candidemia both related and unrelated to the central venous catheter: a retrospective cohort study.

Arias S, Denis O, Montesinos I, Cherifi S, Miendje Deyi VY, Zech F.

Eur J Clin Microbiol Infect Dis. 2017 Mar;36(3):501-507. doi: 10.1007/s10096-016-2825-3. Epub 2016 Nov 10.


Evaluation of a new commercial real-time PCR assay for diagnosis of Pneumocystis jirovecii pneumonia and identification of dihydropteroate synthase (DHPS) mutations.

Montesinos I, Delforge ML, Ajjaham F, Brancart F, Hites M, Jacobs F, Denis O.

Diagn Microbiol Infect Dis. 2017 Jan;87(1):32-36. doi: 10.1016/j.diagmicrobio.2016.10.005. Epub 2016 Oct 7.


Evidence for Human Adaptation and Foodborne Transmission of Livestock-Associated Methicillin-Resistant Staphylococcus aureus.

Larsen J, Stegger M, Andersen PS, Petersen A, Larsen AR, Westh H, Agersø Y, Fetsch A, Kraushaar B, Käsbohrer A, Feβler AT, Schwarz S, Cuny C, Witte W, Butaye P, Denis O, Haenni M, Madec JY, Jouy E, Laurent F, Battisti A, Franco A, Alba P, Mammina C, Pantosti A, Monaco M, Wagenaar JA, de Boer E, van Duijkeren E, Heck M, Domínguez L, Torres C, Zarazaga M, Price LB, Skov RL.

Clin Infect Dis. 2016 Nov 15;63(10):1349-1352. Epub 2016 Sep 20.


In vitro activity of ceftaroline against clinical Staphylococcus aureus isolates collected during a national survey conducted in Belgian hospitals.

Argudín MA, Dodémont M, Taguemount M, Roisin S, de Mendonça R, Deplano A, Nonhoff C, Denis O.

J Antimicrob Chemother. 2017 Jan;72(1):56-59. Epub 2016 Sep 15. Erratum in: J Antimicrob Chemother. 2018 Jul 1;73(7):2001.


Antimicrobial Susceptibility of Pseudomonas aeruginosa Isolated from Cystic Fibrosis Patients in Northern Europe.

Mustafa MH, Chalhoub H, Denis O, Deplano A, Vergison A, Rodriguez-Villalobos H, Tunney MM, Elborn JS, Kahl BC, Traore H, Vanderbist F, Tulkens PM, Van Bambeke F.

Antimicrob Agents Chemother. 2016 Oct 21;60(11):6735-6741. doi: 10.1128/AAC.01046-16. Print 2016 Nov.


Effects of Lipid-Lowering Drugs on Vancomycin Susceptibility of Mycobacteria.

Rens C, Laval F, Daffé M, Denis O, Frita R, Baulard A, Wattiez R, Lefèvre P, Fontaine V.

Antimicrob Agents Chemother. 2016 Sep 23;60(10):6193-9. doi: 10.1128/AAC.00872-16. Print 2016 Oct.


MALDI-TOF MS typing of a nosocomial methicillin-resistant Staphylococcus aureus outbreak in a neonatal intensive care unit.

Steensels D, Deplano A, Denis O, Simon A, Verroken A.

Acta Clin Belg. 2017 Aug;72(4):219-225. doi: 10.1080/17843286.2016.1198521. Epub 2016 Jun 24.


Development of a national EUCAST challenge panel for antimicrobial susceptibility testing.

Desmet S, Verhaegen J, Glupzcynski Y, Van Eldere J, Melin P, Goossens H, Piérard D, Declercq P, Lagrou K, Boel A, Cartuyvels R, Denis O, Vandewal W, Saegeman V.

Clin Microbiol Infect. 2016 Aug;22(8):704-10. doi: 10.1016/j.cmi.2016.05.011. Epub 2016 May 24.


National surveillance of Staphylococcus epidermidis recovered from bloodstream infections in Belgian hospitals.

Deplano A, Vandendriessche S, Nonhoff C, Dodémont M, Roisin S, Denis O.

J Antimicrob Chemother. 2016 Jul;71(7):1815-9. doi: 10.1093/jac/dkw086. Epub 2016 Apr 26.


Low occurrence of the new species Staphylococcus argenteus in a Staphylococcus aureus collection of human isolates from Belgium.

Argudín MA, Dodémont M, Vandendriessche S, Rottiers S, Tribes C, Roisin S, de Mendonça R, Nonhoff C, Deplano A, Denis O.

Eur J Clin Microbiol Infect Dis. 2016 Jun;35(6):1017-22. doi: 10.1007/s10096-016-2632-x. Epub 2016 Apr 4.


Comparison of two chromogenic media and enrichment broth for the detection of carbapenemase-producing Enterobacteriaceae on screening rectal swabs from hospitalized patients.

Heinrichs A, Nonhoff C, Roisin S, De Mendonça R, Adam AS, Dodémont M, Denis O.

J Med Microbiol. 2016 May;65(5):438-41. doi: 10.1099/jmm.0.000244. Epub 2016 Mar 4. No abstract available.


Pan-genome multilocus sequence typing and outbreak-specific reference-based single nucleotide polymorphism analysis to resolve two concurrent Staphylococcus aureus outbreaks in neonatal services.

Roisin S, Gaudin C, De Mendonça R, Bellon J, Van Vaerenbergh K, De Bruyne K, Byl B, Pouseele H, Denis O, Supply P.

Clin Microbiol Infect. 2016 Jun;22(6):520-6. doi: 10.1016/j.cmi.2016.01.024. Epub 2016 Feb 17.


High positive predictive value of Gram stain on catheter-drawn blood samples for the diagnosis of catheter-related bloodstream infection in intensive care neonates.

Deleers M, Dodémont M, Van Overmeire B, Hennequin Y, Vermeylen D, Roisin S, Denis O.

Eur J Clin Microbiol Infect Dis. 2016 Apr;35(4):691-6. doi: 10.1007/s10096-016-2588-x. Epub 2016 Feb 10.


Efficacy of the decolonization of methicillin-resistant Staphylococcus aureus carriers in clinical practice.

Sai N, Laurent C, Strale H, Denis O, Byl B.

Antimicrob Resist Infect Control. 2015 Dec 18;4:56. doi: 10.1186/s13756-015-0096-x. eCollection 2015.


Biofilm formation of ica operon-positive Staphylococcus epidermidis from different sources.

Argudín MA, Vanderhaeghen W, Vandendriessche S, Vandecandelaere I, Denis O, Coenye T, Butaye P.

APMIS. 2015 Dec;123(12):1081-9. doi: 10.1111/apm.12472.


Dynamics of nasal carriage of methicillin-resistant Staphylococcus aureus among healthcare workers in a tertiary-care hospital in Peru.

Garcia C, Acuña-Villaorduña A, Dulanto A, Vandendriessche S, Hallin M, Jacobs J, Denis O.

Eur J Clin Microbiol Infect Dis. 2016 Jan;35(1):89-93. doi: 10.1007/s10096-015-2512-9. Epub 2015 Oct 29.


Detection of mecA- and mecC-Positive Methicillin-Resistant Staphylococcus aureus (MRSA) Isolates by the New Xpert MRSA Gen 3 PCR Assay.

Becker K, Denis O, Roisin S, Mellmann A, Idelevich EA, Knaack D, van Alen S, Kriegeskorte A, Köck R, Schaumburg F, Peters G, Ballhausen B.

J Clin Microbiol. 2016 Jan;54(1):180-4. doi: 10.1128/JCM.02081-15. Epub 2015 Oct 21.


Wide geographical dissemination of the multiresistant Staphylococcus capitis NRCS-A clone in neonatal intensive-care units.

Butin M, Rasigade JP, Martins-Simões P, Meugnier H, Lemriss H, Goering RV, Kearns A, Deighton MA, Denis O, Ibrahimi A, Claris O, Vandenesch F, Picaud JC, Laurent F.

Clin Microbiol Infect. 2016 Jan;22(1):46-52. doi: 10.1016/j.cmi.2015.09.008. Epub 2015 Sep 25.


Low prevalence of mupirocin resistance in Belgian Staphylococcus aureus isolates collected during a 10 year nationwide surveillance.

Nagant C, Deplano A, Nonhoff C, De Mendonça R, Roisin S, Dodémont M, Denis O.

J Antimicrob Chemother. 2016 Jan;71(1):266-7. doi: 10.1093/jac/dkv286. Epub 2015 Sep 16. No abstract available.


Clinical evaluation of a multi-parameter customized respiratory TaqMan(®) array card compared to conventional methods in immunocompromised patients.

Steensels D, Reynders M, Descheemaeker P, Curran MD, Jacobs F, Denis O, Delforge ML, Montesinos I.

J Clin Virol. 2015 Nov;72:36-41. doi: 10.1016/j.jcv.2015.08.022. Epub 2015 Sep 3.


Genome Sequences of Four Staphylococcus capitis NRCS-A Isolates from Geographically Distant Neonatal Intensive Care Units.

Lemriss H, Lemriss S, Martins-Simoes P, Butin M, Lahlou L, Rasigade JP, Kearns A, Denis O, Deighton M, Ibrahimi A, Laurent F, El Kabbaj S.

Genome Announc. 2015 Aug 6;3(4). pii: e00501-15. doi: 10.1128/genomeA.00501-15.


Prospective Two-Center Comparison of Three Chromogenic Agars for Methicillin-Resistant Staphylococcus aureus Screening in Hospitalized Patients.

Dodémont M, Verhulst C, Nonhoff C, Nagant C, Denis O, Kluytmans J.

J Clin Microbiol. 2015 Sep;53(9):3014-6. doi: 10.1128/JCM.01006-15. Epub 2015 Jun 24.


Antimicrobial resistance and population structure of Staphylococcus epidermidis recovered from animals and humans.

Argudín MA, Vanderhaeghen W, Vandendriessche S, Vandecandelaere I, André FX, Denis O, Coenye T, Butaye P.

Vet Microbiol. 2015 Jul 9;178(1-2):105-13. doi: 10.1016/j.vetmic.2015.04.019. Epub 2015 Apr 27.


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