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BRD4 regulates metastatic potential of castration-resistant prostate cancer through AHNAK.

Shafran JS, Andrieu GP, Gyorffy B, Denis GV.

Mol Cancer Res. 2019 May 20. pii: molcanres.1279.2018. doi: 10.1158/1541-7786.MCR-18-1279. [Epub ahead of print]


Arthritis in primary Sjögren's syndrome: Characteristics, outcome and treatment from French multicenter retrospective study.

Mirouse A, Seror R, Vicaut E, Mariette X, Dougados M, Fauchais AL, Deroux A, Dellal A, Costedoat-Chalumeau N, Denis G, Sellam J, Arlet JB, Lavigne C, Urbanski G, Fischer-Dumont D, Diallo A, Fain O, Mékinian A; Club Rhumatismes Inflammation and SNFMI.

Autoimmun Rev. 2019 Jan;18(1):9-14. doi: 10.1016/j.autrev.2018.06.015. Epub 2018 Nov 5. Review.


Abortion storm induced by the live C. abortus vaccine 1B strain in a vaccinated sheep flock, mimicking a natural wild-type infection.

Laroucau K, Aaziz R, Vorimore F, Menard MF, Longbottom D, Denis G.

Vet Microbiol. 2018 Nov;225:31-33. doi: 10.1016/j.vetmic.2018.09.012. Epub 2018 Sep 18.


Inflammatory signatures distinguish metabolic health in African American women with obesity.

Denis GV, Sebastiani P, Bertrand KA, Strissel KJ, Tran AH, Slama J, Medina ND, Andrieu G, Palmer JR.

PLoS One. 2018 May 8;13(5):e0196755. doi: 10.1371/journal.pone.0196755. eCollection 2018.


Bringing Darwin into the social sciences and the humanities: cultural evolution and its philosophical implications.

Blancke S, Denis G.

Hist Philos Life Sci. 2018 Apr 10;40(2):29. doi: 10.1007/s40656-018-0195-0.


BET proteins in abnormal metabolism, inflammation, and the breast cancer microenvironment.

Andrieu GP, Shafran JS, Deeney JT, Bharadwaj KR, Rangarajan A, Denis GV.

J Leukoc Biol. 2018 Aug;104(2):265-274. doi: 10.1002/JLB.5RI0917-380RR. Epub 2018 Mar 1. Review.


BET Proteins Exhibit Transcriptional and Functional Opposition in the Epithelial-to-Mesenchymal Transition.

Andrieu GP, Denis GV.

Mol Cancer Res. 2018 Apr;16(4):580-586. doi: 10.1158/1541-7786.MCR-17-0568. Epub 2018 Feb 7.


Type II Diabetes and Incidence of Estrogen Receptor Negative Breast Cancer in African American Women.

Palmer JR, Castro-Webb N, Bertrand K, Bethea TN, Denis GV.

Cancer Res. 2017 Nov 15;77(22):6462-6469. doi: 10.1158/0008-5472.CAN-17-1903.


Extending the limits of force endurance: Stimulation of the motor or the frontal cortex?

Radel R, Tempest G, Denis G, Besson P, Zory R.

Cortex. 2017 Dec;97:96-108. doi: 10.1016/j.cortex.2017.09.026. Epub 2017 Oct 9.


Relationships Among Obesity, Type 2 Diabetes, and Plasma Cytokines in African American Women.

Denis GV, Sebastiani P, Andrieu G, Tran AH, Strissel KJ, Lombardi FL, Palmer JR.

Obesity (Silver Spring). 2017 Nov;25(11):1916-1920. doi: 10.1002/oby.21943. Epub 2017 Aug 25.


"Obesity-Associated" Breast Cancer in Lean Women: Metabolism and Inflammation as Critical Modifiers of Risk.

Denis GV, Palmer JR.

Cancer Prev Res (Phila). 2017 May;10(5):267-269. doi: 10.1158/1940-6207.CAPR-17-0083. Epub 2017 Apr 13.


Diagnostic performance of colour duplex ultrasonography along with temporal artery biopsy in suspicion of giant cell arteritis.

Roncato C, Allix-Béguec C, Brottier-Mancini E, Gombert B, Denis G.

Clin Exp Rheumatol. 2017 Mar-Apr;35 Suppl 103(1):119-122. Epub 2017 Mar 20.


Diabetes and breast cancer mortality in Black women.

Charlot M, Castro-Webb N, Bethea TN, Bertrand K, Boggs DA, Denis GV, Adams-Campbell LL, Rosenberg L, Palmer JR.

Cancer Causes Control. 2017 Jan;28(1):61-67. doi: 10.1007/s10552-016-0837-z. Epub 2016 Dec 19.


BRD4 Regulates Breast Cancer Dissemination through Jagged1/Notch1 Signaling.

Andrieu G, Tran AH, Strissel KJ, Denis GV.

Cancer Res. 2016 Nov 15;76(22):6555-6567. doi: 10.1158/0008-5472.CAN-16-0559. Epub 2016 Sep 20.


Clinical trials for BET inhibitors run ahead of the science.

Andrieu G, Belkina AC, Denis GV.

Drug Discov Today Technol. 2016 Mar;19:45-50. doi: 10.1016/j.ddtec.2016.06.004. Epub 2016 Jul 21. Review.


Correction to "Barriers to Obtaining Sera and Tissue Specimens of African-American Women for the Advancement of Cancer Research".

Strissel KJ, Nicholas DA, Castagne-Charlotin M, Ko N, Denis GV.

Clin Med Insights Womens Health. 2016 Sep 13;9:35. eCollection 2016.


BET bromodomain proteins and epigenetic regulation of inflammation: implications for type 2 diabetes and breast cancer.

Nicholas DA, Andrieu G, Strissel KJ, Nikolajczyk BS, Denis GV.

Cell Mol Life Sci. 2017 Jan;74(2):231-243. doi: 10.1007/s00018-016-2320-0. Epub 2016 Aug 4. Review.


Barriers to Obtaining Sera and Tissue Specimens of African-American Women for the Advancement of Cancer Research.

Strissel KJ, Nicholas DA, Castagne-Charlotin M, Ko N, Denis GV.

Clin Med Insights Womens Health. 2016 Jul 14;9(Suppl 1):57-61. doi: 10.4137/CMWH.S34698. eCollection 2016. Erratum in: Clin Med Insights Womens Health. 2016 Sep 13;9:35.


BET Bromodomain Proteins Brd2, Brd3 and Brd4 Selectively Regulate Metabolic Pathways in the Pancreatic β-Cell.

Deeney JT, Belkina AC, Shirihai OS, Corkey BE, Denis GV.

PLoS One. 2016 Mar 23;11(3):e0151329. doi: 10.1371/journal.pone.0151329. eCollection 2016.


Efficacy of Azacitidine in autoimmune and inflammatory disorders associated with myelodysplastic syndromes and chronic myelomonocytic leukemia.

Fraison JB, Mekinian A, Grignano E, Kahn JE, Arlet JB, Decaux O, Denis G, Buchdahl AL, Omouri M, Maigne G, Aouba A, Leon N, Berthier S, Liozon E, Park S, Gardin C, Lortholary O, Rossignol J, Fenaux P, Fain O, Braun T.

Leuk Res. 2016 Apr;43:13-7. doi: 10.1016/j.leukres.2016.02.005. Epub 2016 Feb 20.


Associations between metabolic disorders and risk of cancer in Danish men and women--a nationwide cohort study.

Berger SM, Gislason G, Moore LL, Andersson C, Torp-Pedersen C, Denis GV, Schmiegelow MD.

BMC Cancer. 2016 Feb 22;16:133. doi: 10.1186/s12885-016-2122-7.


Systemic inflammatory and autoimmune manifestations associated with myelodysplastic syndromes and chronic myelomonocytic leukaemia: a French multicentre retrospective study.

Mekinian A, Grignano E, Braun T, Decaux O, Liozon E, Costedoat-Chalumeau N, Kahn JE, Hamidou M, Park S, Puéchal X, Toussirot E, Falgarone G, Launay D, Morel N, Trouiller S, Mathian A, Gombert B, Schoindre Y, Lioger B, De Wazieres B, Amoura Z, Buchdaul AL, Georgin-Lavialle S, Dion J, Madaule S, Raffray L, Cathebras P, Piette JC, Rose C, Ziza JM, Lortholary O, Montestruc F, Omouri M, Denis G, Rossignol J, Nimubona S, Adès L, Gardin C, Fenaux P, Fain O.

Rheumatology (Oxford). 2016 Feb;55(2):291-300. doi: 10.1093/rheumatology/kev294. Epub 2015 Sep 8.


Simulated Prosthetic Vision: The Benefits of Computer-Based Object Recognition and Localization.

Macé MJ, Guivarch V, Denis G, Jouffrais C.

Artif Organs. 2015 Jul;39(7):E102-13. doi: 10.1111/aor.12476. Epub 2015 Apr 20.


Simulated prosthetic vision: improving text accessibility with retinal prostheses.

Denis G, Jouffrais C, Mailhes C, Mace MJ.

Conf Proc IEEE Eng Med Biol Soc. 2014;2014:1719-22. doi: 10.1109/EMBC.2014.6943939.


Immune regulators of inflammation in obesity-associated type 2 diabetes and coronary artery disease.

Strissel KJ, Denis GV, Nikolajczyk BS.

Curr Opin Endocrinol Diabetes Obes. 2014 Oct;21(5):330-8. doi: 10.1097/MED.0000000000000085. Review.


Metabolic health reduces risk of obesity-related cancer in framingham study adults.

Moore LL, Chadid S, Singer MR, Kreger BE, Denis GV.

Cancer Epidemiol Biomarkers Prev. 2014 Oct;23(10):2057-65. doi: 10.1158/1055-9965.EPI-14-0240. Epub 2014 Jul 10.


Intrinsic Sex-Linked Variations in Osteogenic and Adipogenic Differentiation Potential of Bone Marrow Multipotent Stromal Cells.

Bragdon B, Burns R, Baker AH, Belkina AC, Morgan EF, Denis GV, Gerstenfeld LC, Schlezinger JJ.

J Cell Physiol. 2015 Feb;230(2):296-307. doi: 10.1002/jcp.24705.


Metabolic disease risk in children by salivary biomarker analysis.

Goodson JM, Kantarci A, Hartman ML, Denis GV, Stephens D, Hasturk H, Yaskell T, Vargas J, Wang X, Cugini M, Barake R, Alsmadi O, Al-Mutawa S, Ariga J, Soparkar P, Behbehani J, Behbehani K, Welty F.

PLoS One. 2014 Jun 10;9(6):e98799. doi: 10.1371/journal.pone.0098799. eCollection 2014.


Inflammatory arthritis in patients with myelodysplastic syndromes: a multicenter retrospective study and literature review of 68 cases.

Mekinian A, Braun T, Decaux O, Falgarone G, Toussirot E, Raffray L, Omouri M, Gombert B, De Wazieres B, Buchdaul AL, Ziza JM, Launay D, Denis G, Madaule S, Rose C, Grignano E, Fenaux P, Fain O; Club Rhumatismes et Inflammation (CRI), Groupe Francophone des Myélodysplasies (GFM); Société Nationale Française de Médecine Interne (SNFMI).

Medicine (Baltimore). 2014 Jan;93(1):1-10. doi: 10.1097/MD.0000000000000011. Review.


The double bromodomain protein Brd2 promotes B cell expansion and mitogenesis.

Belkina AC, Blanton WP, Nikolajczyk BS, Denis GV.

J Leukoc Biol. 2014 Mar;95(3):451-60. doi: 10.1189/jlb.1112588. Epub 2013 Dec 6.


Relevance of partitioning DLCO to detect pulmonary hypertension in systemic sclerosis.

Sivova N, Launay D, Wémeau-Stervinou L, De Groote P, Remy-Jardin M, Denis G, Lambert M, Lamblin N, Morell-Dubois S, Fertin M, Lefevre G, Sobanski V, Le Rouzic O, Hatron PY, Wallaert B, Hachulla E, Perez T.

PLoS One. 2013 Oct 18;8(10):e78001. doi: 10.1371/journal.pone.0078001. eCollection 2013.


Protein arginine methyltransferase 5 (PRMT5) inhibition induces lymphoma cell death through reactivation of the retinoblastoma tumor suppressor pathway and polycomb repressor complex 2 (PRC2) silencing.

Chung J, Karkhanis V, Tae S, Yan F, Smith P, Ayers LW, Agostinelli C, Pileri S, Denis GV, Baiocchi RA, Sif S.

J Biol Chem. 2013 Dec 6;288(49):35534-47. doi: 10.1074/jbc.M113.510669. Epub 2013 Nov 4.


ChemR23 knockout mice display mild obesity but no deficit in adipocyte differentiation.

Rouger L, Denis GR, Luangsay S, Parmentier M.

J Endocrinol. 2013 Nov 7;219(3):279-89. doi: 10.1530/JOE-13-0106. Print 2013 Dec.


Healthy obese persons: how can they be identified and do metabolic profiles stratify risk?

Denis GV, Hamilton JA.

Curr Opin Endocrinol Diabetes Obes. 2013 Oct;20(5):369-76. doi: 10.1097/ Review.


B cells promote inflammation in obesity and type 2 diabetes through regulation of T-cell function and an inflammatory cytokine profile.

DeFuria J, Belkina AC, Jagannathan-Bogdan M, Snyder-Cappione J, Carr JD, Nersesova YR, Markham D, Strissel KJ, Watkins AA, Zhu M, Allen J, Bouchard J, Toraldo G, Jasuja R, Obin MS, McDonnell ME, Apovian C, Denis GV, Nikolajczyk BS.

Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):5133-8. doi: 10.1073/pnas.1215840110. Epub 2013 Mar 11.


BET protein function is required for inflammation: Brd2 genetic disruption and BET inhibitor JQ1 impair mouse macrophage inflammatory responses.

Belkina AC, Nikolajczyk BS, Denis GV.

J Immunol. 2013 Apr 1;190(7):3670-8. doi: 10.4049/jimmunol.1202838. Epub 2013 Feb 18.


Brd2 gene disruption causes "metabolically healthy" obesity: epigenetic and chromatin-based mechanisms that uncouple obesity from type 2 diabetes.

Wang F, Deeney JT, Denis GV.

Vitam Horm. 2013;91:49-75. doi: 10.1016/B978-0-12-407766-9.00003-1. Review.


'Metabolically healthy obesity': origins and implications.

Denis GV, Obin MS.

Mol Aspects Med. 2013 Feb;34(1):59-70. doi: 10.1016/j.mam.2012.10.004. Epub 2012 Oct 13. Review.


Mental health effects from urban bed bug infestation (Cimex lectularius L.): a cross-sectional study.

Susser SR, Perron S, Fournier M, Jacques L, Denis G, Tessier F, Roberge P.

BMJ Open. 2012 Sep 25;2(5). pii: e000838. doi: 10.1136/bmjopen-2012-000838. Print 2012.


The outliers become a stampede as immunometabolism reaches a tipping point.

Nikolajczyk BS, Jagannathan-Bogdan M, Denis GV.

Immunol Rev. 2012 Sep;249(1):253-75. doi: 10.1111/j.1600-065X.2012.01142.x. Review.


BET bromodomain inhibition as a novel strategy for reactivation of HIV-1.

Banerjee C, Archin N, Michaels D, Belkina AC, Denis GV, Bradner J, Sebastiani P, Margolis DM, Montano M.

J Leukoc Biol. 2012 Dec;92(6):1147-54. doi: 10.1189/jlb.0312165. Epub 2012 Jul 16.


BET domain co-regulators in obesity, inflammation and cancer.

Belkina AC, Denis GV.

Nat Rev Cancer. 2012 Jun 22;12(7):465-77. doi: 10.1038/nrc3256. Review.


Late pregnancy abortions: an analysis of Québec stillbirth data, 1981-2006.

Auger N, Denis G.

Int J Public Health. 2012 Apr;57(2):443-6. doi: 10.1007/s00038-011-0313-1. Epub 2011 Oct 21.


Parallel imaging microfluidic cytometer.

Ehrlich DJ, McKenna BK, Evans JG, Belkina AC, Denis GV, Sherr DH, Cheung MC.

Methods Cell Biol. 2011;102:49-75. doi: 10.1016/B978-0-12-374912-3.00003-1. Review.


Pneumocystis jirovecii colonization in patients with systemic autoimmune diseases: prevalence, risk factors of colonization and outcome.

Mekinian A, Durand-Joly I, Hatron PY, Moranne O, Denis G, Dei-Cas E, Morell-Dubois S, Lambert M, Launay D, Delhaes L, Hachulla E, Queyrel V.

Rheumatology (Oxford). 2011 Mar;50(3):569-77. doi: 10.1093/rheumatology/keq314. Epub 2010 Nov 18.


[Giant biloma in the course of choledocholithiasis].

Denis G, Bonneau G, Franco-Gillet K, Guillon E, Braeckman L, Alix M.

Presse Med. 2011 Feb;40(2):193-6. doi: 10.1016/j.lpm.2010.09.018. Epub 2010 Nov 13. French. No abstract available.


Obesity genes and insulin resistance.

Belkina AC, Denis GV.

Curr Opin Endocrinol Diabetes Obes. 2010 Oct;17(5):472-7. doi: 10.1097/MED.0b013e32833c5c48. Review.


An emerging role for bromodomain-containing proteins in chromatin regulation and transcriptional control of adipogenesis.

Denis GV, Nikolajczyk BS, Schnitzler GR.

FEBS Lett. 2010 Aug 4;584(15):3260-8. doi: 10.1016/j.febslet.2010.05.030. Epub 2010 May 21. Review.


Isolated megakaryoblastic bone sarcoma revealing acute myeloproliferative syndrome.

Desplechin A, Mekinian A, Rossignol J, Denis G, Gosset P, Cambier N, Rose C.

Joint Bone Spine. 2010 May;77(3):277-8. doi: 10.1016/j.jbspin.2010.03.005. Epub 2010 May 4. No abstract available.


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