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Items: 20

1.

Pregnancy Immunogenetics and Genomics: Implications for Pregnancy-Related Complications and Autoimmune Disease.

Yeung HY, Dendrou CA.

Annu Rev Genomics Hum Genet. 2019 Aug 31;20:73-97. doi: 10.1146/annurev-genom-083118-014943. Epub 2019 Mar 8.

PMID:
30848957
2.

HLA variation and disease.

Dendrou CA, Petersen J, Rossjohn J, Fugger L.

Nat Rev Immunol. 2018 May;18(5):325-339. doi: 10.1038/nri.2017.143. Epub 2018 Jan 2. Review.

PMID:
29292391
3.

Immunomodulation in multiple sclerosis: promises and pitfalls.

Dendrou CA, Fugger L.

Curr Opin Immunol. 2017 Dec;49:37-43. doi: 10.1016/j.coi.2017.08.013. Epub 2017 Sep 18. Review.

PMID:
28926740
4.

Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank.

Cortes A, Dendrou CA, Motyer A, Jostins L, Vukcevic D, Dilthey A, Donnelly P, Leslie S, Fugger L, McVean G.

Nat Genet. 2017 Sep;49(9):1311-1318. doi: 10.1038/ng.3926. Epub 2017 Jul 31.

5.

Structural and regulatory diversity shape HLA-C protein expression levels.

Kaur G, Gras S, Mobbs JI, Vivian JP, Cortes A, Barber T, Kuttikkatte SB, Jensen LT, Attfield KE, Dendrou CA, Carrington M, McVean G, Purcell AW, Rossjohn J, Fugger L.

Nat Commun. 2017 Jun 26;8:15924. doi: 10.1038/ncomms15924.

6.

Severe B-cell-mediated CNS disease secondary to alemtuzumab therapy.

Haghikia A, Dendrou CA, Schneider R, Grüter T, Postert T, Matzke M, Stephanik H, Fugger L, Gold R.

Lancet Neurol. 2017 Feb;16(2):104-106. doi: 10.1016/S1474-4422(16)30382-9. No abstract available.

PMID:
28102146
7.

Neuroinflammation - using big data to inform clinical practice.

Dendrou CA, McVean G, Fugger L.

Nat Rev Neurol. 2016 Dec;12(12):685-698. doi: 10.1038/nrneurol.2016.171. Epub 2016 Nov 18. Review.

PMID:
27857124
8.

Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity.

Dendrou CA, Cortes A, Shipman L, Evans HG, Attfield KE, Jostins L, Barber T, Kaur G, Kuttikkatte SB, Leach OA, Desel C, Faergeman SL, Cheeseman J, Neville MJ, Sawcer S, Compston A, Johnson AR, Everett C, Bell JI, Karpe F, Ultsch M, Eigenbrot C, McVean G, Fugger L.

Sci Transl Med. 2016 Nov 2;8(363):363ra149.

9.

Class II HLA interactions modulate genetic risk for multiple sclerosis.

Moutsianas L, Jostins L, Beecham AH, Dilthey AT, Xifara DK, Ban M, Shah TS, Patsopoulos NA, Alfredsson L, Anderson CA, Attfield KE, Baranzini SE, Barrett J, Binder TMC, Booth D, Buck D, Celius EG, Cotsapas C, D'Alfonso S, Dendrou CA, Donnelly P, Dubois B, Fontaine B, Fugger L, Goris A, Gourraud PA, Graetz C, Hemmer B, Hillert J; International IBD Genetics Consortium (IIBDGC), Kockum I, Leslie S, Lill CM, Martinelli-Boneschi F, Oksenberg JR, Olsson T, Oturai A, Saarela J, Søndergaard HB, Spurkland A, Taylor B, Winkelmann J, Zipp F, Haines JL, Pericak-Vance MA, Spencer CCA, Stewart G, Hafler DA, Ivinson AJ, Harbo HF, Hauser SL, De Jager PL, Compston A, McCauley JL, Sawcer S, McVean G.

Nat Genet. 2015 Oct;47(10):1107-1113. doi: 10.1038/ng.3395. Epub 2015 Sep 7.

10.

Immunopathology of multiple sclerosis.

Dendrou CA, Fugger L, Friese MA.

Nat Rev Immunol. 2015 Sep 15;15(9):545-58. doi: 10.1038/nri3871. Epub 2015 Aug 7. Review.

PMID:
26250739
11.

Please mind the gap: axonal transport deficits in multiple sclerosis neurodegeneration.

Dendrou CA, Fugger L.

Neuron. 2014 Dec 17;84(6):1105-7. doi: 10.1016/j.neuron.2014.12.012.

12.

A clinical conundrum: the detrimental effect of TNF antagonists in multiple sclerosis.

Dendrou CA, Bell JI, Fugger L.

Pharmacogenomics. 2013 Sep;14(12):1397-404. doi: 10.2217/pgs.13.140.

PMID:
24024893
13.

Postthymic expansion in human CD4 naive T cells defined by expression of functional high-affinity IL-2 receptors.

Pekalski ML, Ferreira RC, Coulson RM, Cutler AJ, Guo H, Smyth DJ, Downes K, Dendrou CA, Castro Dopico X, Esposito L, Coleman G, Stevens HE, Nutland S, Walker NM, Guy C, Dunger DB, Wallace C, Tree TI, Todd JA, Wicker LS.

J Immunol. 2013 Mar 15;190(6):2554-66. doi: 10.4049/jimmunol.1202914. Epub 2013 Feb 15.

14.

Weighing in on autoimmune disease: Big data tip the scale.

Dendrou CA, Bell JI, Fugger L.

Nat Med. 2013 Feb;19(2):138-9. doi: 10.1038/nm.3087. No abstract available.

PMID:
23389608
15.

TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis.

Gregory AP, Dendrou CA, Attfield KE, Haghikia A, Xifara DK, Butter F, Poschmann G, Kaur G, Lambert L, Leach OA, Prömel S, Punwani D, Felce JH, Davis SJ, Gold R, Nielsen FC, Siegel RM, Mann M, Bell JI, McVean G, Fugger L.

Nature. 2012 Aug 23;488(7412):508-511. doi: 10.1038/nature11307.

16.

Bridging the gap from genetic association to functional understanding: the next generation of mouse models of multiple sclerosis.

Attfield KE, Dendrou CA, Fugger L.

Immunol Rev. 2012 Jul;248(1):10-22. doi: 10.1111/j.1600-065X.2012.01132.x. Review.

PMID:
22725951
17.

Nonobese diabetic congenic strain analysis of autoimmune diabetes reveals genetic complexity of the Idd18 locus and identifies Vav3 as a candidate gene.

Fraser HI, Dendrou CA, Healy B, Rainbow DB, Howlett S, Smink LJ, Gregory S, Steward CA, Todd JA, Peterson LB, Wicker LS.

J Immunol. 2010 May 1;184(9):5075-84. doi: 10.4049/jimmunol.0903734. Epub 2010 Apr 2.

18.

Fluorescence intensity normalisation: correcting for time effects in large-scale flow cytometric analysis.

Dendrou CA, Fung E, Esposito L, Todd JA, Wicker LS, Plagnol V.

Adv Bioinformatics. 2009:476106. doi: 10.1155/2009/476106. Epub 2009 Nov 17.

19.

Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource.

Dendrou CA, Plagnol V, Fung E, Yang JH, Downes K, Cooper JD, Nutland S, Coleman G, Himsworth M, Hardy M, Burren O, Healy B, Walker NM, Koch K, Ouwehand WH, Bradley JR, Wareham NJ, Todd JA, Wicker LS.

Nat Genet. 2009 Sep;41(9):1011-5. doi: 10.1038/ng.434. Epub 2009 Aug 23.

20.

The IL-2/CD25 pathway determines susceptibility to T1D in humans and NOD mice.

Dendrou CA, Wicker LS.

J Clin Immunol. 2008 Nov;28(6):685-96. doi: 10.1007/s10875-008-9237-9. Epub 2008 Sep 9.

PMID:
18780166

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