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Items: 1 to 50 of 261

1.

Specialization of small non-conjugative plasmids in Escherichia coli according to their family types.

Branger C, Ledda A, Billard-Pomares T, Doublet B, Barbe V, Roche D, Médigue C, Arlet G, Denamur E.

Microb Genom. 2019 Aug 7. doi: 10.1099/mgen.0.000281. [Epub ahead of print]

2.

A simple, reproducible and cost-effective procedure to analyse gut phageome: from phage isolation to bioinformatic approach.

d'Humières C, Touchon M, Dion S, Cury J, Ghozlane A, Garcia-Garcera M, Bouchier C, Ma L, Denamur E, P C Rocha E.

Sci Rep. 2019 Aug 5;9(1):11331. doi: 10.1038/s41598-019-47656-w.

3.

In vitro acquisition and evolution of bla CTX-M gene bearing plasmids in Escherichia coli: advantage of the F2:A1:B- IncF pandemic plasmid over IncC plasmids.

Mahérault AC, Kemble H, Magnan M, Gachet B, Roche D, Nagard HL, Tenaillon O, Denamur E, Branger C, Landraud L.

Antimicrob Agents Chemother. 2019 Jul 22. pii: AAC.01130-19. doi: 10.1128/AAC.01130-19. [Epub ahead of print]

4.

mcr-9, an Inducible Gene Encoding an Acquired Phosphoethanolamine Transferase in Escherichia coli, and Its Origin.

Kieffer N, Royer G, Decousser JW, Bourrel AS, Palmieri M, Ortiz De La Rosa JM, Jacquier H, Denamur E, Nordmann P, Poirel L.

Antimicrob Agents Chemother. 2019 Aug 23;63(9). pii: e00965-19. doi: 10.1128/AAC.00965-19. Print 2019 Sep.

PMID:
31209009
5.

High-density lipoprotein (HDL) particle size and concentration changes in septic shock patients.

Tanaka S, Diallo D, Delbosc S, Genève C, Zappella N, Yong-Sang J, Patche J, Harrois A, Hamada S, Denamur E, Montravers P, Duranteau J, Meilhac O.

Ann Intensive Care. 2019 Jun 13;9(1):68. doi: 10.1186/s13613-019-0541-8.

6.

Characterization and rapid identification of phylogroup G in Escherichia coli, a lineage with high virulence and antibiotic resistance potential.

Clermont O, Dixit OVA, Vangchhia B, Condamine B, Dion S, Bridier-Nahmias A, Denamur E, Gordon D.

Environ Microbiol. 2019 Aug;21(8):3107-3117. doi: 10.1111/1462-2920.14713. Epub 2019 Jun 28.

PMID:
31188527
7.

The Arginine Deiminase Operon Is Responsible for a Fitness Trade-Off in Extended-Spectrum-β-Lactamase-Producing Strains of Escherichia coli.

Billard-Pomares T, Clermont O, Castellanos M, Magdoud F, Royer G, Condamine B, Fouteau S, Barbe V, Roche D, Cruveiller S, Médigue C, Pognard D, Glodt J, Dion S, Rigal O, Picard B, Denamur E, Branger C.

Antimicrob Agents Chemother. 2019 Jul 25;63(8). pii: e00635-19. doi: 10.1128/AAC.00635-19. Print 2019 Aug.

PMID:
31138573
8.

CD89 Is a Potent Innate Receptor for Bacteria and Mediates Host Protection from Sepsis.

de Tymowski C, Heming N, Correia MDT, Abbad L, Chavarot N, Le Stang MB, Flament H, Bex J, Boedec E, Bounaix C, Soler-Torronteras R, Denamur E, Galicier L, Oksenhendler E, Fehling HJ, Pinheiro da Silva F, Benhamou M, Monteiro RC, Ben Mkaddem S.

Cell Rep. 2019 Apr 16;27(3):762-775.e5. doi: 10.1016/j.celrep.2019.03.062.

9.

Ceftriaxone and Cefotaxime Have Similar Effects on the Intestinal Microbiota in Human Volunteers Treated by Standard-Dose Regimens.

Burdet C, Grall N, Linard M, Bridier-Nahmias A, Benhayoun M, Bourabha K, Magnan M, Clermont O, d'Humières C, Tenaillon O, Denamur E, Massias L, Tubiana S, Alavoine L, Andremont A, Mentré F, Duval X; CEREMI Group.

Antimicrob Agents Chemother. 2019 May 24;63(6). pii: e02244-18. doi: 10.1128/AAC.02244-18. Print 2019 Jun.

PMID:
30936104
10.

Pneumonia-Specific Escherichia coli with Distinct Phylogenetic and Virulence Profiles, France, 2012-2014.

La Combe B, Clermont O, Messika J, Eveillard M, Kouatchet A, Lasocki S, Corvec S, Lakhal K, Billard-Pomares T, Fernandes R, Armand-Lefevre L, Bourdon S, Reignier J, Fihman V, de Prost N, Bador J, Goret J, Wallet F, Denamur E, Ricard JD; COLOCOLI group; COLOCOLI Group.

Emerg Infect Dis. 2019 Apr;25(4):710-718. doi: 10.3201/eid2504.180944.

11.

Colistin resistance in Parisian inpatient faecal Escherichia coli as the result of two distinct evolutionary pathways.

Bourrel AS, Poirel L, Royer G, Darty M, Vuillemin X, Kieffer N, Clermont O, Denamur E, Nordmann P, Decousser JW; IAME Resistance Group.

J Antimicrob Chemother. 2019 Jun 1;74(6):1521-1530. doi: 10.1093/jac/dkz090.

PMID:
30863849
12.

Determination of Escherichia coli phylogroups in elderly patients with urinary tract infection or asymptomatic bacteriuria.

Amarsy R, Guéret D, Benmansour H, Flicoteaux R, Berçot B, Meunier F, Mougari F, Jacquier H, Pean de Ponfilly G, Clermont O, Denamur E, Teixeira A, Cambau E.

Clin Microbiol Infect. 2019 Jul;25(7):839-844. doi: 10.1016/j.cmi.2018.12.032. Epub 2019 Jan 12.

PMID:
30648603
13.

PlaScope: a targeted approach to assess the plasmidome from genome assemblies at the species level.

Royer G, Decousser JW, Branger C, Dubois M, Médigue C, Denamur E, Vallenet D.

Microb Genom. 2018 Sep;4(9). doi: 10.1099/mgen.0.000211.

14.

Genotypic and phenotypic characteristics of Escherichia coli involved in transfusion-transmitted bacterial infections: implications for preventive strategies.

Desroches M, Clermont O, Lafeuillade B, Rodriguez C, Darty M, Royer G, Bouvet O, Ounnoughene N, Noizat-Pirenne F, Denamur E, Decousser JW.

Transfusion. 2018 Aug;58(8):1940-1950. doi: 10.1111/trf.14812.

PMID:
30198609
15.

Extended-spectrum β-lactamase-encoding genes are spreading on a wide range of Escherichia coli plasmids existing prior to the use of third-generation cephalosporins.

Branger C, Ledda A, Billard-Pomares T, Doublet B, Fouteau S, Barbe V, Roche D, Cruveiller S, Médigue C, Castellanos M, Decré D, Drieux-Rouze L, Clermont O, Glodt J, Tenaillon O, Cloeckaert A, Arlet G, Denamur E.

Microb Genom. 2018 Sep;4(9). doi: 10.1099/mgen.0.000203. Epub 2018 Aug 6.

16.

Core elements of the vegetative replication control of the Inc1 plasmid pO104_90 of Escherichia coli O104:H4 also regulate its transfer frequency.

Berger M, Berger P, Denamur E, Mellmann A, Dobrindt U.

Int J Med Microbiol. 2018 Oct;308(7):962-968. doi: 10.1016/j.ijmm.2018.07.003. Epub 2018 Jul 18.

PMID:
30055976
17.

ClermonTyping: an easy-to-use and accurate in silico method for Escherichia genus strain phylotyping.

Beghain J, Bridier-Nahmias A, Le Nagard H, Denamur E, Clermont O.

Microb Genom. 2018 Jul;4(7). doi: 10.1099/mgen.0.000192. Epub 2018 Jun 19.

18.

The Odyssey of the Ancestral Escherich Strain through Culture Collections: an Example of Allopatric Diversification.

Desroches M, Royer G, Roche D, Mercier-Darty M, Vallenet D, Médigue C, Bastard K, Rodriguez C, Clermont O, Denamur E, Decousser JW.

mSphere. 2018 Jan 31;3(1). pii: e00553-17. doi: 10.1128/mSphere.00553-17. eCollection 2018 Jan-Feb.

19.

Decreased susceptibility to chlorhexidine affects a quarter of Escherichia coli isolates responsible for pneumonia in ICU patients.

La Combe B, Bleibtreu A, Messika J, Fernandes R, Clermont O, Branger C, Billard-Pomares T, Barnaud G, Magdoud F, Eveillard M, Kouatchet A, Lasocki S, Asfar P, Corvec S, Lakhal K, Armand-Lefevre L, Wolff M, Timsit JF, Bourdon S, Reignier J, Martin S, Fihman V, de Prost N, Bador J, Charles PE, Goret J, Boyer A, Wallet F, Jaillette E, Nseir S, Landraud L, Ruimy R, Danin PE, Dellamonica J, Cremniter J, Frat JP, Jauréguy F, Clec'h C, Decré D, Maury E, Dreyfuss D, Denamur E, Ricard JD.

Intensive Care Med. 2018 Apr;44(4):531-533. doi: 10.1007/s00134-018-5061-8. Epub 2018 Jan 29. No abstract available.

PMID:
29379992
20.

Pathophysiology of Escherichia coli pneumonia: Respective contribution of pathogenicity islands to virulence.

Phillips-Houlbracq M, Ricard JD, Foucrier A, Yoder-Himes D, Gaudry S, Bex J, Messika J, Margetis D, Chatel J, Dobrindt U, Denamur E, Roux D.

Int J Med Microbiol. 2018 Mar;308(2):290-296. doi: 10.1016/j.ijmm.2018.01.003. Epub 2018 Jan 5.

PMID:
29325882
21.

Evolution of a Dominant Natural Isolate of Escherichia coli in the Human Gut over the Course of a Year Suggests a Neutral Evolution with Reduced Effective Population Size.

Ghalayini M, Launay A, Bridier-Nahmias A, Clermont O, Denamur E, Lescat M, Tenaillon O.

Appl Environ Microbiol. 2018 Mar 1;84(6). pii: e02377-17. doi: 10.1128/AEM.02377-17. Print 2018 Mar 15.

22.

Phenotype inference in an Escherichia coli strain panel.

Galardini M, Koumoutsi A, Herrera-Dominguez L, Cordero Varela JA, Telzerow A, Wagih O, Wartel M, Clermont O, Denamur E, Typas A, Beltrao P.

Elife. 2017 Dec 27;6. pii: e31035. doi: 10.7554/eLife.31035.

23.

Erratum: Diversity of the auxotrophic requirements in natural isolates of Escherichia coli.

Bouvet O, Bourdelier E, Glodt J, Clermont O, Denamur E.

Microbiology. 2017 Aug;163(8):1260-1261. doi: 10.1099/mic.0.000520. No abstract available.

PMID:
28820365
24.

Extra-corporeal membrane oxygenation-associated infections: implication of extra-intestinal pathogenic Escherichia coli clones.

Messika J, Clermont O, Landraud L, Schmidt M, Aubry A, Sougakoff W, Fernandes R, Combes A, Denamur E, Ricard JD.

J Med Microbiol. 2017 Aug;66(8):1189-1195. doi: 10.1099/jmm.0.000554. Epub 2017 Aug 4.

PMID:
28771132
25.

Diversity of the auxotrophic requirements in natural isolates of Escherichia coli.

Bouvet O, Bourdelier E, Glodt J, Clermont O, Denamur E.

Microbiology. 2017 Jun;163(6):891-899. doi: 10.1099/mic.0.000482. Epub 2017 Jun 26. Erratum in: Microbiology. 2017 Aug;163(8):1260-1261.

PMID:
28651684
26.

Fine-Scale Structure Analysis Shows Epidemic Patterns of Clonal Complex 95, a Cosmopolitan Escherichia coli Lineage Responsible for Extraintestinal Infection.

Gordon DM, Geyik S, Clermont O, O'Brien CL, Huang S, Abayasekara C, Rajesh A, Kennedy K, Collignon P, Pavli P, Rodriguez C, Johnston BD, Johnson JR, Decousser JW, Denamur E.

mSphere. 2017 May 31;2(3). pii: e00168-17. doi: 10.1128/mSphere.00168-17. eCollection 2017 May-Jun.

27.

[Molecular epidemiology and kinetics of early Escherichia coli urinary tract infections in kidney transplant recipients].

Tashk P, Lecronier M, Clermont O, Renvoisé A, Aubry A, Barrou B, Hertig A, Lescat M, Tenaillon O, Denamur E, Tourret J.

Nephrol Ther. 2017 Jun;13(4):236-244. doi: 10.1016/j.nephro.2016.10.008. Epub 2017 May 30. French.

PMID:
28576434
28.

KPC-3-producing ST167 Escherichia coli from mussels bought at a retail market in Tunisia.

Mani Y, Mansour W, Mammeri H, Denamur E, Saras E, Boujâafar N, Bouallègue O, Madec JY, Haenni M.

J Antimicrob Chemother. 2017 Aug 1;72(8):2403-2404. doi: 10.1093/jac/dkx124. No abstract available.

PMID:
28472479
29.

Change in the Structure of Escherichia coli Population and the Pattern of Virulence Genes along a Rural Aquatic Continuum.

Petit F, Clermont O, Delannoy S, Servais P, Gourmelon M, Fach P, Oberlé K, Fournier M, Denamur E, Berthe T.

Front Microbiol. 2017 Apr 18;8:609. doi: 10.3389/fmicb.2017.00609. eCollection 2017.

30.

Molecular epidemiology of penicillinase-producing Neisseria gonorrhoeae isolates in France.

Micaëlo M, Goubard A, La Ruche G, Denamur E, Tenaillon O, Cambau E, Jacquier H, Bercot B.

Clin Microbiol Infect. 2017 Dec;23(12):968-973. doi: 10.1016/j.cmi.2017.04.010. Epub 2017 Apr 13.

31.

Day-to-Day Dynamics of Commensal Escherichia coli in Zimbabwean Cows Evidence Temporal Fluctuations within a Host-Specific Population Structure.

Massot M, Couffignal C, Clermont O, D'Humières C, Chatel J, Plault N, Andremont A, Caron A, Mentré F, Denamur E.

Appl Environ Microbiol. 2017 Jun 16;83(13). pii: e00659-17. doi: 10.1128/AEM.00659-17. Print 2017 Jul 1.

32.

Structural Alteration of OmpR as a Source of Ertapenem Resistance in a CTX-M-15-Producing Escherichia coli O25b:H4 Sequence Type 131 Clinical Isolate.

Dupont H, Choinier P, Roche D, Adiba S, Sookdeb M, Branger C, Denamur E, Mammeri H.

Antimicrob Agents Chemother. 2017 Apr 24;61(5). pii: e00014-17. doi: 10.1128/AAC.00014-17. Print 2017 May.

33.

Association of the 16S rRNA methylase gene rmtB with a novel insertion sequence element belonging to the ISL3 family.

Morel F, Decousser JW, Kumanski S, Cambau E, Denamur E, Berçot B.

Int J Antimicrob Agents. 2017 Jan;49(1):117-118. doi: 10.1016/j.ijantimicag.2016.10.002. Epub 2016 Oct 21. No abstract available.

PMID:
28244374
34.

Two levels of specialization in bacteraemic Escherichia coli strains revealed by their comparison with commensal strains.

Clermont O, Couffignal C, Blanco J, Mentré F, Picard B, Denamur E; COLIVILLE and COLIBAFI groups.

Epidemiol Infect. 2017 Apr;145(5):872-882. doi: 10.1017/S0950268816003010. Epub 2016 Dec 28.

PMID:
28029088
35.

Strain-specific impact of the high-pathogenicity island on virulence in extra-intestinal pathogenic Escherichia coli.

Smati M, Magistro G, Adiba S, Wieser A, Picard B, Schubert S, Denamur E.

Int J Med Microbiol. 2017 Jan;307(1):44-56. doi: 10.1016/j.ijmm.2016.11.004. Epub 2016 Nov 22.

PMID:
27923724
36.

Escherichia coli Probiotic Strain ED1a in Pigs Has a Limited Impact on the Gut Carriage of Extended-Spectrum-β-Lactamase-Producing E. coli.

Mourand G, Paboeuf F, Fleury MA, Jouy E, Bougeard S, Denamur E, Kempf I.

Antimicrob Agents Chemother. 2016 Dec 27;61(1). pii: e01293-16. doi: 10.1128/AAC.01293-16. Print 2017 Jan.

37.

Erratum: Global phylogeography and evolutionary history of Shigella dysenteriae type 1.

Njamkepo E, Fawal N, Tran-Dien A, Hawkey J, Strockbine N, Jenkins C, Talukder KA, Bercion R, Kuleshov K, Kolínská R, Russell JE, Kaftyreva L, Accou-Demartin M, Karas A, Vandenberg O, Mather AE, Mason CJ, Page AJ, Ramamurthy T, Bizet C, Gamian A, Carle I, Sow AG, Bouchier C, Wester AL, Lejay-Collin M, Fonkoua MC, Le Hello S, Blaser MJ, Jernberg C, Ruckly C, Mérens A, Page AL, Aslett M, Roggentin P, Fruth A, Denamur E, Venkatesan M, Bercovier H, Bodhidatta L, Chiou CS, Clermont D, Colonna B, Egorova S, Pazhani GP, Ezernitchi AV, Guigon G, Harris SR, Izumiya H, Korzeniowska-Kowal A, Lutyńska A, Gouali M, Grimont F, Langendorf C, Marejková M, Peterson LA, Perez-Perez G, Ngandjio A, Podkolzin A, Souche E, Makarova M, Shipulin GA, Ye C, Žemličková H, Herpay M, Grimont PA, Parkhill J, Sansonetti P, Holt KE, Brisse S, Thomson NR, Weill FX.

Nat Microbiol. 2016 Oct 3;1(11):16209. doi: 10.1038/nmicrobiol.2016.209. No abstract available.

PMID:
27694821
38.

Using long-term experimental evolution to uncover the patterns and determinants of molecular evolution of an Escherichia coli natural isolate in the streptomycin-treated mouse gut.

Lescat M, Launay A, Ghalayini M, Magnan M, Glodt J, Pintard C, Dion S, Denamur E, Tenaillon O.

Mol Ecol. 2017 Apr;26(7):1802-1817. doi: 10.1111/mec.13851. Epub 2016 Oct 18.

39.

Immunosuppressive Treatment Alters Secretion of Ileal Antimicrobial Peptides and Gut Microbiota, and Favors Subsequent Colonization by Uropathogenic Escherichia coli.

Tourret J, Willing BP, Dion S, MacPherson J, Denamur E, Finlay BB.

Transplantation. 2017 Jan;101(1):74-82. doi: 10.1097/TP.0000000000001492.

PMID:
27681266
40.

Prospective Cohort Study of the Relative Abundance of Extended-Spectrum-Beta-Lactamase-Producing Escherichia coli in the Gut of Patients Admitted to Hospitals.

de Lastours V, Chopin D, Jacquier H, d'Humières C, Burdet C, Chau F, Denamur E, Fantin B.

Antimicrob Agents Chemother. 2016 Oct 21;60(11):6941-6944. doi: 10.1128/AAC.01328-16. Print 2016 Nov.

41.

Global phylogeography and evolutionary history of Shigella dysenteriae type 1.

Njamkepo E, Fawal N, Tran-Dien A, Hawkey J, Strockbine N, Jenkins C, Talukder KA, Bercion R, Kuleshov K, Kolínská R, Russell JE, Kaftyreva L, Accou-Demartin M, Karas A, Vandenberg O, Mather AE, Mason CJ, Page AJ, Ramamurthy T, Bizet C, Gamian A, Carle I, Sow AG, Bouchier C, Wester AL, Lejay-Collin M, Fonkoua MC, Le Hello S, Blaser MJ, Jernberg C, Ruckly C, Mérens A, Page AL, Aslett M, Roggentin P, Fruth A, Denamur E, Venkatesan M, Bercovier H, Bodhidatta L, Chiou CS, Clermont D, Colonna B, Egorova S, Pazhani GP, Ezernitchi AV, Guigon G, Harris SR, Izumiya H, Korzeniowska-Kowal A, Lutyńska A, Gouali M, Grimont F, Langendorf C, Marejková M, Peterson LA, Perez-Perez G, Ngandjio A, Podkolzin A, Souche E, Makarova M, Shipulin GA, Ye C, Žemličková H, Herpay M, Grimont PA, Parkhill J, Sansonetti P, Holt KE, Brisse S, Thomson NR, Weill FX.

Nat Microbiol. 2016 Mar 21;1:16027. doi: 10.1038/nmicrobiol.2016.27. Erratum in: Nat Microbiol. 2016 Oct 03;1(11):16209.

PMID:
27572446
42.

Rare Spontaneous Loss of Multiresistance Gene Carrying IncI/ST12 Plasmid in Escherichia coli in Pig Microbiota.

Mourand G, Touzain F, Jouy E, Fleury MA, Denamur E, Kempf I.

Antimicrob Agents Chemother. 2016 Sep 23;60(10):6046-9. doi: 10.1128/AAC.00864-16. Print 2016 Oct.

43.

Bacteriophage LM33_P1, a fast-acting weapon against the pandemic ST131-O25b:H4 Escherichia coli clonal complex.

Dufour N, Clermont O, La Combe B, Messika J, Dion S, Khanna V, Denamur E, Ricard JD, Debarbieux L; ColoColi group.

J Antimicrob Chemother. 2016 Nov;71(11):3072-3080. Epub 2016 Jul 7.

44.

Links between Transcription, Environmental Adaptation and Gene Variability in Escherichia coli: Correlations between Gene Expression and Gene Variability Reflect Growth Efficiencies.

Feugeas JP, Tourret J, Launay A, Bouvet O, Hoede C, Denamur E, Tenaillon O.

Mol Biol Evol. 2016 Oct;33(10):2515-29. doi: 10.1093/molbev/msw105. Epub 2016 Jun 28.

PMID:
27352853
45.

Small Intestine Early Innate Immunity Response during Intestinal Colonization by Escherichia coli Depends on Its Extra-Intestinal Virulence Status.

Tourret J, Willing BP, Croxen MA, Dufour N, Dion S, Wachtel S, Denamur E, Finlay BB.

PLoS One. 2016 Apr 20;11(4):e0153034. doi: 10.1371/journal.pone.0153034. eCollection 2016.

46.

Population Phylogenomics of Extraintestinal Pathogenic Escherichia coli.

Tourret J, Denamur E.

Microbiol Spectr. 2016 Feb;4(1). doi: 10.1128/microbiolspec.UTI-0010-2012.

PMID:
26999389
47.

Phylogenetic, virulence and antibiotic resistance characteristics of commensal strain populations of Escherichia coli from community subjects in the Paris area in 2010 and evolution over 30 years.

Massot M, Daubié AS, Clermont O, Jauréguy F, Couffignal C, Dahbi G, Mora A, Blanco J, Branger C, Mentré F, Eddi A, Picard B, Denamur E, The Coliville Group.

Microbiology. 2016 Apr;162(4):642-650. doi: 10.1099/mic.0.000242. Epub 2016 Jan 28.

48.

Escherichia coli Population Structure and Antibiotic Resistance at a Buffalo/Cattle Interface in Southern Africa.

Mercat M, Clermont O, Massot M, Ruppe E, de Garine-Wichatitsky M, Miguel E, Valls Fox H, Cornelis D, Andremont A, Denamur E, Caron A.

Appl Environ Microbiol. 2015 Dec 28;82(5):1459-1467. doi: 10.1128/AEM.03771-15.

49.

Emergence of Antimicrobial-Resistant Escherichia coli of Animal Origin Spreading in Humans.

Skurnik D, Clermont O, Guillard T, Launay A, Danilchanka O, Pons S, Diancourt L, Lebreton F, Kadlec K, Roux D, Jiang D, Dion S, Aschard H, Denamur M, Cywes-Bentley C, Schwarz S, Tenaillon O, Andremont A, Picard B, Mekalanos J, Brisse S, Denamur E.

Mol Biol Evol. 2016 Apr;33(4):898-914. doi: 10.1093/molbev/msv280. Epub 2015 Nov 26.

50.

Hepcidin as a Major Component of Renal Antibacterial Defenses against Uropathogenic Escherichia coli.

Houamel D, Ducrot N, Lefebvre T, Daher R, Moulouel B, Sari MA, Letteron P, Lyoumi S, Millot S, Tourret J, Bouvet O, Vaulont S, Vandewalle A, Denamur E, Puy H, Beaumont C, Gouya L, Karim Z.

J Am Soc Nephrol. 2016 Mar;27(3):835-46. doi: 10.1681/ASN.2014101035. Epub 2015 Aug 20.

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