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Items: 19


The interplay between genetic risk factors and proteolytic dysregulation in the pathophysiology of inflammatory bowel disease.

Solà Tapias N, Vergnolle N, Denadai-Souza A, Barreau F.

J Crohns Colitis. 2020 Feb 22. pii: jjaa033. doi: 10.1093/ecco-jcc/jjaa033. [Epub ahead of print]


Ephrin-B2 signaling in the spinal cord as a player in post-inflammatory and stress-induced visceral hypersensitivity.

Theofanous SA, Florens MV, Appeltans I, Denadai Souza A, Wood JN, Wouters MM, Boeckxstaens GE.

Neurogastroenterol Motil. 2020 Jan 31:e13782. doi: 10.1111/nmo.13782. [Epub ahead of print]


Sexual dimorphism in PAR2-dependent regulation of primitive colonic cells.

Noguerol J, Roustan PJ, N'Taye M, Delcombel L, Rolland C, Guiraud L, Sagnat D, Edir A, Bonnart C, Denadai-Souza A, Deraison C, Vergnolle N, Racaud-Sultan C.

Biol Sex Differ. 2019 Sep 6;10(1):47. doi: 10.1186/s13293-019-0262-6.


Active thrombin produced by the intestinal epithelium controls mucosal biofilms.

Motta JP, Denadai-Souza A, Sagnat D, Guiraud L, Edir A, Bonnart C, Sebbag M, Rousset P, Lapeyre A, Seguy C, Mathurine-Thomas N, Galipeau HJ, Bonnet D, Alric L, Buret AG, Wallace JL, Dufour A, Verdu EF, Hollenberg MD, Oswald E, Serino M, Deraison C, Vergnolle N.

Nat Commun. 2019 Jul 19;10(1):3224. doi: 10.1038/s41467-019-11140-w.


Histamine-mediated potentiation of transient receptor potential (TRP) ankyrin 1 and TRP vanilloid 4 signaling in submucosal neurons in patients with irritable bowel syndrome.

Balemans D, Aguilera-Lizarraga J, Florens MV, Jain P, Denadai-Souza A, Viola MF, Alpizar YA, Van Der Merwe S, Vanden Berghe P, Talavera K, Vanner S, Wouters MM, Boeckxstaens GE.

Am J Physiol Gastrointest Liver Physiol. 2019 Mar 1;316(3):G338-G349. doi: 10.1152/ajpgi.00116.2018. Epub 2019 Jan 10.


FAK alternative splice mRNA variants expression pattern in colorectal cancer.

Devaud C, Tilkin-Mariamé AF, Vignolle-Vidoni A, Souleres P, Denadai-Souza A, Rolland C, Duthoit C, Blanpied C, Chabot S, Bouillé P, Lluel P, Vergnolle N, Racaud-Sultan C, Ferrand A.

Int J Cancer. 2019 Jul 15;145(2):494-502. doi: 10.1002/ijc.32120. Epub 2019 Feb 14.


5-oxoETE triggers nociception in constipation-predominant irritable bowel syndrome through MAS-related G protein-coupled receptor D.

Bautzova T, Hockley JRF, Perez-Berezo T, Pujo J, Tranter MM, Desormeaux C, Barbaro MR, Basso L, Le Faouder P, Rolland C, Malapert P, Moqrich A, Eutamene H, Denadai-Souza A, Vergnolle N, Smith ESJ, Hughes DI, Barbara G, Dietrich G, Bulmer DC, Cenac N.

Sci Signal. 2018 Dec 18;11(561). pii: eaal2171. doi: 10.1126/scisignal.aal2171.


Thrombin modifies growth, proliferation and apoptosis of human colon organoids: a protease-activated receptor 1- and protease-activated receptor 4-dependent mechanism.

Sébert M, Denadai-Souza A, Quaranta M, Racaud-Sultan C, Chabot S, Lluel P, Monjotin N, Alric L, Portier G, Kirzin S, Bonnet D, Ferrand A, Vergnolle N.

Br J Pharmacol. 2018 Sep;175(18):3656-3668. doi: 10.1111/bph.14430. Epub 2018 Aug 7.


Functional Proteomic Profiling of Secreted Serine Proteases in Health and Inflammatory Bowel Disease.

Denadai-Souza A, Bonnart C, Tapias NS, Marcellin M, Gilmore B, Alric L, Bonnet D, Burlet-Schiltz O, Hollenberg MD, Vergnolle N, Deraison C.

Sci Rep. 2018 May 18;8(1):7834. doi: 10.1038/s41598-018-26282-y.


Effect of tryptase inhibition on joint inflammation: a pharmacological and lentivirus-mediated gene transfer study.

Denadai-Souza A, Ribeiro CM, Rolland C, Thouard A, Deraison C, Scavone C, Gonzalez-Dunia D, Vergnolle N, Avellar MCW.

Arthritis Res Ther. 2017 Jun 6;19(1):124. doi: 10.1186/s13075-017-1326-9.


Epithelial expression and function of trypsin-3 in irritable bowel syndrome.

Rolland-Fourcade C, Denadai-Souza A, Cirillo C, Lopez C, Jaramillo JO, Desormeaux C, Cenac N, Motta JP, Larauche M, Taché Y, Vanden Berghe P, Neunlist M, Coron E, Kirzin S, Portier G, Bonnet D, Alric L, Vanner S, Deraison C, Vergnolle N.

Gut. 2017 Oct;66(10):1767-1778. doi: 10.1136/gutjnl-2016-312094. Epub 2017 Jan 17.


Suppression of MAPK attenuates neuronal cell death induced by activated glia-conditioned medium in alpha-synuclein overexpressing SH-SY5Y cells.

Yshii LM, Denadai-Souza A, Vasconcelos AR, Avellar MC, Scavone C.

J Neuroinflammation. 2015 Oct 26;12:193. doi: 10.1186/s12974-015-0412-7.


Peripheral neurokinin-1 receptors contribute to kaolin-induced acute monoarthritis in rats.

Camargo LL, Denadai-Souza A, Yshii LM, Mesquita FP, Soares AG, Lima C, Schenka A, Grant A, Fernandes E, Muscará MN, Costa SK.

Neuroimmunomodulation. 2015;22(6):373-84. doi: 10.1159/000381549. Epub 2015 Jun 12.


Dynamic changes in the spatio-temporal expression of the β-defensin SPAG11C in the developing rat epididymis and its regulation by androgens.

Ribeiro CM, Queiróz DB, Patrão MT, Denadai-Souza A, Romano RM, Silva EJ, Avellar MC.

Mol Cell Endocrinol. 2015 Mar 15;404:141-50. doi: 10.1016/j.mce.2015.01.013. Epub 2015 Feb 2.


Role of transient receptor potential vanilloid 4 in rat joint inflammation.

Denadai-Souza A, Martin L, de Paula MA, de Avellar MC, Muscará MN, Vergnolle N, Cenac N.

Arthritis Rheum. 2012 Jun;64(6):1848-58. doi: 10.1002/art.34345. Epub 2011 Dec 19.


PAR(2) and temporomandibular joint inflammation in the rat.

Denadai-Souza A, Cenac N, Casatti CA, Câmara PR, Yshii LM, Costa SK, Vergnolle N, Muscará MN.

J Dent Res. 2010 Oct;89(10):1123-8. doi: 10.1177/0022034510375284. Epub 2010 Jul 22.


Differing effects of exogenous and endogenous hydrogen sulphide in carrageenan-induced knee joint synovitis in the rat.

Ekundi-Valentim E, Santos KT, Camargo EA, Denadai-Souza A, Teixeira SA, Zanoni CI, Grant AD, Wallace J, Muscará MN, Costa SK.

Br J Pharmacol. 2010 Apr;159(7):1463-74. doi: 10.1111/j.1476-5381.2010.00640.x. Epub 2010 Feb 5.


Putative antinociceptive action of nitric oxide in the caudal part of the spinal trigeminal nucleus during chronic carrageenan-induced arthritis in the rat temporomandibular joint.

Tesser-Viscaíno SA, Denadai-Souza A, Teixeira SA, Ervolino E, Cruz-Rizzolo RJ, Costa SK, Muscará MN, Casatti CA.

Brain Res. 2009 Dec 11;1302:85-96. doi: 10.1016/j.brainres.2009.09.056. Epub 2009 Sep 19.


Participation of peripheral tachykinin NK1 receptors in the carrageenan-induced inflammation of the rat temporomandibular joint.

Denadai-Souza A, Camargo Lde L, Ribela MT, Keeble JE, Costa SK, Muscará MN.

Eur J Pain. 2009 Sep;13(8):812-9. doi: 10.1016/j.ejpain.2008.09.012. Epub 2008 Oct 31.


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