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Items: 1 to 50 of 320

1.

Aurora A-Selective Inhibitor LY3295668 Leads to Dominant Mitotic Arrest, Apoptosis in Cancer Cells, and Shows Potent Preclinical Antitumor Efficacy.

Du J, Yan L, Torres R, Gong X, Bian H, Marugán C, Boehnke K, Baquero C, Hui YH, Chapman SC, Yang Y, Zeng Y, Bogner SM, Foreman RT, Capen A, Donoho GP, Van Horn RD, Barnard DS, Dempsey JA, Beckmann RP, Marshall MS, Chio LC, Qian Y, Webster YW, Aggarwal A, Chu S, Bhattachar S, Stancato LF, Dowless MS, Iversen PW, Manro JR, Walgren JL, Halstead BW, Dieter MZ, Martinez R, Bhagwat SV, Kreklau EL, Lallena MJ, Ye XS, Patel BKR, Reinhard C, Plowman GD, Barda DA, Henry JR, Buchanan SG, Campbell RM.

Mol Cancer Ther. 2019 Dec;18(12):2207-2219. doi: 10.1158/1535-7163.MCT-18-0529. Epub 2019 Sep 17.

PMID:
31530649
2.

On the Horizon of Aging and Physical Activity Research.

Jakobi JM, Dempsey JA, Hellsten Y, Monette R, Kalmar JM.

Appl Physiol Nutr Metab. 2019 Jul 17. doi: 10.1139/apnm-2018-0738. [Epub ahead of print]

PMID:
31314999
3.

Central sleep apnea: misunderstood and mistreated!

Dempsey JA.

F1000Res. 2019 Jun 28;8. pii: F1000 Faculty Rev-981. doi: 10.12688/f1000research.18358.1. eCollection 2019. Review.

4.

Respiratory Determinants of Exercise Limitation: Focus on Phrenic Afferents and the Lung Vasculature.

Dempsey JA.

Clin Chest Med. 2019 Jun;40(2):331-342. doi: 10.1016/j.ccm.2019.02.002. Review.

PMID:
31078213
5.

Update on Chemoreception: Influence on Cardiorespiratory Regulation and Pathophysiology.

Dempsey JA, Smith CA.

Clin Chest Med. 2019 Jun;40(2):269-283. doi: 10.1016/j.ccm.2019.02.001. Review.

PMID:
31078209
6.

Competition for blood flow distribution between respiratory and locomotor muscles: implications for muscle fatigue.

Sheel AW, Boushel R, Dempsey JA.

J Appl Physiol (1985). 2018 Sep 1;125(3):820-831. doi: 10.1152/japplphysiol.00189.2018. Epub 2018 Jun 7. Review.

7.

The CDK4/6 Inhibitor Abemaciclib Induces a T Cell Inflamed Tumor Microenvironment and Enhances the Efficacy of PD-L1 Checkpoint Blockade.

Schaer DA, Beckmann RP, Dempsey JA, Huber L, Forest A, Amaladas N, Li Y, Wang YC, Rasmussen ER, Chin D, Capen A, Carpenito C, Staschke KA, Chung LA, Litchfield LM, Merzoug FF, Gong X, Iversen PW, Buchanan S, de Dios A, Novosiadly RD, Kalos M.

Cell Rep. 2018 Mar 13;22(11):2978-2994. doi: 10.1016/j.celrep.2018.02.053.

8.

Physiological Redundancy and the Integrative Responses to Exercise.

Joyner MJ, Dempsey JA.

Cold Spring Harb Perspect Med. 2018 May 1;8(5). pii: a029660. doi: 10.1101/cshperspect.a029660. Review.

PMID:
28490539
9.

Sleep Apnea: Types, Mechanisms, and Clinical Cardiovascular Consequences.

Javaheri S, Barbe F, Campos-Rodriguez F, Dempsey JA, Khayat R, Javaheri S, Malhotra A, Martinez-Garcia MA, Mehra R, Pack AI, Polotsky VY, Redline S, Somers VK.

J Am Coll Cardiol. 2017 Feb 21;69(7):841-858. doi: 10.1016/j.jacc.2016.11.069. Review.

10.
11.

Editorial.

Boushel R, Hargreaves M, Harridge S, Essen-Gustavsson B, Henriksson J, Raven PB, Dempsey JA, Harridge S, Richter EA, Secher NH, Mitchell JH, van Hall G, Jansson E, Holm I.

Scand J Med Sci Sports. 2015 Dec;25 Suppl 4:1-6. doi: 10.1111/sms.12609. No abstract available.

PMID:
26589111
12.

Peripheral chemoreceptors determine the respiratory sensitivity of central chemoreceptors to CO2 : role of carotid body CO2.

Smith CA, Blain GM, Henderson KS, Dempsey JA.

J Physiol. 2015 Sep 15;593(18):4225-43. doi: 10.1113/JP270114. Epub 2015 Aug 16.

13.

Humans In Hypoxia: A Conspiracy Of Maladaptation?!

Dempsey JA, Morgan BJ.

Physiology (Bethesda). 2015 Jul;30(4):304-16. doi: 10.1152/physiol.00007.2015. Review.

14.

Reply to Joseph.

Morgan BJ, Adrian R, Bates ML, Dopp JM, Dempsey JA.

J Appl Physiol (1985). 2014 Dec 15;117(12):1525. doi: 10.1152/japplphysiol.00893.2014. No abstract available.

15.

Quantifying hypoxia-induced chemoreceptor sensitivity in the awake rodent.

Morgan BJ, Adrian R, Bates ML, Dopp JM, Dempsey JA.

J Appl Physiol (1985). 2014 Oct 1;117(7):816-24. doi: 10.1152/japplphysiol.00484.2014. Epub 2014 Jul 31.

16.

Career perspective: Jerome A. Dempsey.

Dempsey JA.

Extrem Physiol Med. 2014 Jul 7;3:13. doi: 10.1186/2046-7648-3-13. eCollection 2014.

17.

Pathophysiology of human ventilatory control.

Dempsey JA, Smith CA.

Eur Respir J. 2014 Aug;44(2):495-512. doi: 10.1183/09031936.00048514. Epub 2014 Jun 12. Review.

18.

Role of chemoreception in cardiorespiratory acclimatization to, and deacclimatization from, hypoxia.

Dempsey JA, Powell FL, Bisgard GE, Blain GM, Poulin MJ, Smith CA.

J Appl Physiol (1985). 2014 Apr 1;116(7):858-66. doi: 10.1152/japplphysiol.01126.2013. Epub 2013 Dec 26. Review.

19.

Physiology in medicine: obstructive sleep apnea pathogenesis and treatment--considerations beyond airway anatomy.

Dempsey JA, Xie A, Patz DS, Wang D.

J Appl Physiol (1985). 2014 Jan 1;116(1):3-12. doi: 10.1152/japplphysiol.01054.2013. Epub 2013 Nov 7. Review.

20.

Are type III-IV muscle afferents required for a normal steady-state exercise hyperpnoea in humans?

Dempsey JA, Blain GM, Amann M.

J Physiol. 2014 Feb 1;592(3):463-74. doi: 10.1113/jphysiol.2013.261925. Epub 2013 Sep 2. Review.

21.

Mentoring through teamwork: lessons learned.

Dempsey JA.

Physiologist. 2013 Jul;56(4):89, 91-3.

PMID:
23901620
22.

Limits to ventilation (for sure!) and exercise (maybe?) in mild chronic obstructive pulmonary disease.

Dempsey JA.

Am J Respir Crit Care Med. 2013 Jun 15;187(12):1282-3. doi: 10.1164/rccm.201304-0667ED. No abstract available.

PMID:
23767899
23.

Central sleep apnea.

Javaheri S, Dempsey JA.

Compr Physiol. 2013 Jan;3(1):141-63. doi: 10.1002/cphy.c110057. Review.

PMID:
23720283
24.

Effects of stabilizing or increasing respiratory motor outputs on obstructive sleep apnea.

Xie A, Teodorescu M, Pegelow DF, Teodorescu MC, Gong Y, Fedie JE, Dempsey JA.

J Appl Physiol (1985). 2013 Jul 1;115(1):22-33. doi: 10.1152/japplphysiol.00064.2013. Epub 2013 Apr 18.

25.

Respiratory influences on muscle sympathetic nerve activity and vascular conductance in the steady state.

Limberg JK, Morgan BJ, Schrage WG, Dempsey JA.

Am J Physiol Heart Circ Physiol. 2013 Jun 15;304(12):H1615-23. doi: 10.1152/ajpheart.00112.2013. Epub 2013 Apr 12.

26.

Role of central/peripheral chemoreceptors and their interdependence in the pathophysiology of sleep apnea.

Dempsey JA, Smith CA, Blain GM, Xie A, Gong Y, Teodorescu M.

Adv Exp Med Biol. 2012;758:343-9. doi: 10.1007/978-94-007-4584-1_46. Review.

PMID:
23080181
27.

New perspectives concerning feedback influences on cardiorespiratory control during rhythmic exercise and on exercise performance.

Dempsey JA.

J Physiol. 2012 Sep 1;590(17):4129-44. doi: 10.1113/jphysiol.2012.233908. Epub 2012 Jul 23.

28.

Control of breathing during exercise.

Forster HV, Haouzi P, Dempsey JA.

Compr Physiol. 2012 Jan;2(1):743-77. doi: 10.1002/cphy.c100045. Review.

PMID:
23728984
29.

Implications of group III and IV muscle afferents for high-intensity endurance exercise performance in humans.

Amann M, Blain GM, Proctor LT, Sebranek JJ, Pegelow DF, Dempsey JA.

J Physiol. 2011 Nov 1;589(Pt 21):5299-309. doi: 10.1113/jphysiol.2011.213769. Epub 2011 Aug 30.

30.

The heterogeneity of obstructive sleep apnea (predominant obstructive vs pure obstructive apnea).

Xie A, Bedekar A, Skatrud JB, Teodorescu M, Gong Y, Dempsey JA.

Sleep. 2011 Jun 1;34(6):745-50. doi: 10.5665/SLEEP.1040.

31.

Editor's note regarding Lundberg et al. Letter to the Editor.

Dempsey JA.

J Appl Physiol (1985). 2011 Aug;111(2):615. doi: 10.1152/japplphysiol.00651.2011. Epub 2011 May 26. No abstract available.

32.

State of the journal of applied physiology: 2011.

Dempsey JA.

J Appl Physiol (1985). 2011 Jun;110(6):1503-5. doi: 10.1152/japplphysiol.00488.2011. Epub 2011 Apr 21. No abstract available.

33.

Cardiorespiratory responses to exercise in CHF: a conspiracy of maladaptation.

Dempsey JA.

J Physiol. 2010 Aug 1;588(Pt 15):2683. doi: 10.1113/jphysiol.2010.193805. No abstract available.

34.

Group III and IV muscle afferents contribute to ventilatory and cardiovascular response to rhythmic exercise in humans.

Amann M, Blain GM, Proctor LT, Sebranek JJ, Pegelow DF, Dempsey JA.

J Appl Physiol (1985). 2010 Oct;109(4):966-76. doi: 10.1152/japplphysiol.00462.2010. Epub 2010 Jul 15.

35.

Impact of pulmonary system limitations on locomotor muscle fatigue in patients with COPD.

Amann M, Regan MS, Kobitary M, Eldridge MW, Boutellier U, Pegelow DF, Dempsey JA.

Am J Physiol Regul Integr Comp Physiol. 2010 Jul;299(1):R314-24. doi: 10.1152/ajpregu.00183.2010. Epub 2010 May 5.

36.

Peripheral chemoreceptors determine the respiratory sensitivity of central chemoreceptors to CO(2).

Blain GM, Smith CA, Henderson KS, Dempsey JA.

J Physiol. 2010 Jul 1;588(Pt 13):2455-71. doi: 10.1113/jphysiol.2010.187211. Epub 2010 Apr 26.

37.

An interdependent model of central/peripheral chemoreception: evidence and implications for ventilatory control.

Smith CA, Forster HV, Blain GM, Dempsey JA.

Respir Physiol Neurobiol. 2010 Oct 31;173(3):288-97. doi: 10.1016/j.resp.2010.02.015. Epub 2010 Mar 4. Review.

38.

Pathophysiology of sleep apnea.

Dempsey JA, Veasey SC, Morgan BJ, O'Donnell CP.

Physiol Rev. 2010 Jan;90(1):47-112. doi: 10.1152/physrev.00043.2008. Review. Erratum in: Physiol Rev.2010 Apr;90(2):797-8.

39.

Impact factor and its role in academic promotion.

Brusasco V, Dinh-Xuan AT, Leff AR, Adler KB, Glenny RW, Dempsey JA, Levy ML, Panettieri R, Reddel HK, Singh D, Virchow JC.

Eur Respir J. 2009 Dec;34(6):1499-500. doi: 10.1183/09031936.00094109. No abstract available.

40.

Impact factor and its role in academic promotion: a statement adopted by the International Respiratory Journal Editors Roundtable.

Dempsey JA.

J Appl Physiol (1985). 2009 Oct;107(4):1005. doi: 10.1152/japplphysiol.00891.2009. Epub 2009 Aug 13. No abstract available.

41.

Sympathetic restraint of muscle blood flow during hypoxic exercise.

Stickland MK, Smith CA, Soriano BJ, Dempsey JA.

Am J Physiol Regul Integr Comp Physiol. 2009 May;296(5):R1538-46. doi: 10.1152/ajpregu.90918.2008. Epub 2009 Mar 18.

42.

Contribution of the carotid body chemoreceptors to eupneic ventilation in the intact, unanesthetized dog.

Blain GM, Smith CA, Henderson KS, Dempsey JA.

J Appl Physiol (1985). 2009 May;106(5):1564-73. doi: 10.1152/japplphysiol.91590.2008. Epub 2009 Feb 26.

43.

Influence of cerebral blood flow on breathing stability.

Xie A, Skatrud JB, Barczi SR, Reichmuth K, Morgan BJ, Mont S, Dempsey JA.

J Appl Physiol (1985). 2009 Mar;106(3):850-6. doi: 10.1152/japplphysiol.90914.2008. Epub 2008 Dec 31.

44.

Opioid-mediated muscle afferents inhibit central motor drive and limit peripheral muscle fatigue development in humans.

Amann M, Proctor LT, Sebranek JJ, Pegelow DF, Dempsey JA.

J Physiol. 2009 Jan 15;587(1):271-83. doi: 10.1113/jphysiol.2008.163303. Epub 2008 Nov 17.

45.

Somatosensory feedback from the limbs exerts inhibitory influences on central neural drive during whole body endurance exercise.

Amann M, Proctor LT, Sebranek JJ, Eldridge MW, Pegelow DF, Dempsey JA.

J Appl Physiol (1985). 2008 Dec;105(6):1714-24. doi: 10.1152/japplphysiol.90456.2008. Epub 2008 Sep 11.

46.

Update in the understanding of respiratory limitations to exercise performance in fit, active adults.

Dempsey JA, McKenzie DC, Haverkamp HC, Eldridge MW.

Chest. 2008 Sep;134(3):613-622. doi: 10.1378/chest.07-2730. Review.

PMID:
18779196
47.

Respiratory system determinants of peripheral fatigue and endurance performance.

Dempsey JA, Amann M, Romer LM, Miller JD.

Med Sci Sports Exerc. 2008 Mar;40(3):457-61. doi: 10.1249/MSS.0b013e31815f8957.

PMID:
18379207
48.

Carotid chemoreceptor modulation of sympathetic vasoconstrictor outflow during exercise in healthy humans.

Stickland MK, Morgan BJ, Dempsey JA.

J Physiol. 2008 Mar 15;586(6):1743-54. doi: 10.1113/jphysiol.2007.147421. Epub 2008 Jan 17.

49.

Exercise-induced respiratory muscle work: effects on blood flow, fatigue and performance.

Dempsey JA, Miller JD, Romer L, Amann M, Smith CA.

Adv Exp Med Biol. 2008;605:209-12. No abstract available.

PMID:
18085273
50.

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