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Items: 16

1.

Electrophysiological characterization of drug response in hSC-derived cardiomyocytes using voltage-sensitive optical platforms.

Pfeiffer-Kaushik ER, Smith GL, Cai B, Dempsey GT, Hortigon-Vinagre MP, Zamora V, Feng S, Ingermanson R, Zhu R, Hariharan V, Nguyen C, Pierson J, Gintant GA, Tung L.

J Pharmacol Toxicol Methods. 2019 Jul 15:106612. doi: 10.1016/j.vascn.2019.106612. [Epub ahead of print]

PMID:
31319140
2.

Inhale, exhale: Probing the inside-out mechanism of nicotine addiction using novel fluorescent sensors.

McManus OB, Werley CA, Dempsey GT.

J Gen Physiol. 2019 Jun 3;151(6):714-717. doi: 10.1085/jgp.201912325. Epub 2019 Mar 22. No abstract available.

PMID:
30902836
3.

Scalable Measurements of Intrinsic Excitability in Human iPS Cell-Derived Excitatory Neurons Using All-Optical Electrophysiology.

Williams LA, Joshi V, Murphy M, Ferrante J, Werley CA, Brookings T, McManus O, Grosse J, Davies CH, Dempsey GT.

Neurochem Res. 2019 Mar;44(3):714-725. doi: 10.1007/s11064-018-2694-5. Epub 2019 Jan 2.

PMID:
30603979
4.

All-Optical Electrophysiology for Disease Modeling and Pharmacological Characterization of Neurons.

Werley CA, Brookings T, Upadhyay H, Williams LA, McManus OB, Dempsey GT.

Curr Protoc Pharmacol. 2017 Sep 11;78:11.20.1-11.20.24. doi: 10.1002/cpph.25.

5.

Targeting neuronal function for CNS drug discovery.

Hempel CM, Werley CA, Dempsey GT, Gerber DJ.

Drug Discov Today Technol. 2017 Mar;23:17-25. doi: 10.1016/j.ddtec.2017.03.005. Epub 2017 May 6. Review.

PMID:
28647082
6.

Cardiotoxicity screening with simultaneous optogenetic pacing, voltage imaging and calcium imaging.

Dempsey GT, Chaudhary KW, Atwater N, Nguyen C, Brown BS, McNeish JD, Cohen AE, Kralj JM.

J Pharmacol Toxicol Methods. 2016 Sep-Oct;81:240-50. doi: 10.1016/j.vascn.2016.05.003. Epub 2016 May 13.

PMID:
27184445
7.

Characterization and development of photoactivatable fluorescent proteins for single-molecule-based superresolution imaging.

Wang S, Moffitt JR, Dempsey GT, Xie XS, Zhuang X.

Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8452-7. doi: 10.1073/pnas.1406593111. Epub 2014 May 27.

8.

A user's guide to localization-based super-resolution fluorescence imaging.

Dempsey GT.

Methods Cell Biol. 2013;114:561-92. doi: 10.1016/B978-0-12-407761-4.00024-5.

PMID:
23931523
9.

Phosphine quenching of cyanine dyes as a versatile tool for fluorescence microscopy.

Vaughan JC, Dempsey GT, Sun E, Zhuang X.

J Am Chem Soc. 2013 Jan 30;135(4):1197-200. doi: 10.1021/ja3105279. Epub 2013 Jan 17.

10.

Molecular architecture and assembly principles of Vibrio cholerae biofilms.

Berk V, Fong JC, Dempsey GT, Develioglu ON, Zhuang X, Liphardt J, Yildiz FH, Chu S.

Science. 2012 Jul 13;337(6091):236-9. doi: 10.1126/science.1222981.

11.

Multicolor super-resolution fluorescence imaging via multi-parameter fluorophore detection.

Bates M, Dempsey GT, Chen KH, Zhuang X.

Chemphyschem. 2012 Jan 16;13(1):99-107. doi: 10.1002/cphc.201100735. Epub 2011 Dec 23.

12.

Evaluation of fluorophores for optimal performance in localization-based super-resolution imaging.

Dempsey GT, Vaughan JC, Chen KH, Bates M, Zhuang X.

Nat Methods. 2011 Nov 6;8(12):1027-36. doi: 10.1038/nmeth.1768.

13.

Photoswitching mechanism of cyanine dyes.

Dempsey GT, Bates M, Kowtoniuk WE, Liu DR, Tsien RY, Zhuang X.

J Am Chem Soc. 2009 Dec 30;131(51):18192-3. doi: 10.1021/ja904588g.

14.

Fast in vitro translation system immobilized on a surface via specific biotinylation of the ribosome.

Stapulionis R, Wang Y, Dempsey GT, Khudaravalli R, Nielsen KM, Cooperman BS, Goldman YE, Knudsen CR.

Biol Chem. 2008 Sep;389(9):1239-49. doi: 10.1515/BC.2008.141.

PMID:
18713011
15.

Single-molecule structural dynamics of EF-G--ribosome interaction during translocation.

Wang Y, Qin H, Kudaravalli RD, Kirillov SV, Dempsey GT, Pan D, Cooperman BS, Goldman YE.

Biochemistry. 2007 Sep 25;46(38):10767-75. Epub 2007 Aug 30.

PMID:
17727272
16.

Multicolor super-resolution imaging with photo-switchable fluorescent probes.

Bates M, Huang B, Dempsey GT, Zhuang X.

Science. 2007 Sep 21;317(5845):1749-53. Epub 2007 Aug 16.

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