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Items: 32

1.

p53 modeling as a route to mesothelioma patients stratification and novel therapeutic identification.

Tian K, Bakker E, Hussain M, Guazzelli A, Alhebshi H, Meysami P, Demonacos C, Schwartz JM, Mutti L, Krstic-Demonacos M.

J Transl Med. 2018 Oct 13;16(1):282. doi: 10.1186/s12967-018-1650-0.

2.

Insight into glucocorticoid receptor signalling through interactome model analysis.

Bakker E, Tian K, Mutti L, Demonacos C, Schwartz JM, Krstic-Demonacos M.

PLoS Comput Biol. 2017 Nov 6;13(11):e1005825. doi: 10.1371/journal.pcbi.1005825. eCollection 2017 Nov.

3.

Immunotherapy advances for mesothelioma treatment.

Bakker E, Guazzelli A, Ashtiani F, Demonacos C, Krstic-Demonacos M, Mutti L.

Expert Rev Anticancer Ther. 2017 Sep;17(9):799-814. doi: 10.1080/14737140.2017.1358091. Epub 2017 Jul 31. Review.

PMID:
28724330
4.

Promising investigational drug candidates in phase I and phase II clinical trials for mesothelioma.

Guazzelli A, Bakker E, Tian K, Demonacos C, Krstic-Demonacos M, Mutti L.

Expert Opin Investig Drugs. 2017 Aug;26(8):933-944. doi: 10.1080/13543784.2017.1351545. Epub 2017 Jul 12. Review.

PMID:
28679291
5.

Differential regulation of cell death pathways by the microenvironment correlates with chemoresistance and survival in leukaemia.

Qattan MY, Bakker EY, Rajendran R, Chen DW, Saha V, Liu J, Zeef L, Schwartz JM, Mutti L, Demonacos C, Krstic-Demonacos M.

PLoS One. 2017 Jun 5;12(6):e0178606. doi: 10.1371/journal.pone.0178606. eCollection 2017.

6.

miR-663a regulates growth of colon cancer cells, after administration of antimicrobial peptides, by targeting CXCR4-p21 pathway.

Kuroda K, Fukuda T, Krstic-Demonacos M, Demonacos C, Okumura K, Isogai H, Hayashi M, Saito K, Isogai E.

BMC Cancer. 2017 Jan 7;17(1):33. doi: 10.1186/s12885-016-3003-9.

7.

Non-symmetrical furan-amidines as novel leads for the treatment of cancer and malaria.

Alnabulsi S, Santina E, Russo I, Hussein B, Kadirvel M, Chadwick A, Bichenkova EV, Bryce RA, Nolan K, Demonacos C, Stratford IJ, Freeman S.

Eur J Med Chem. 2016 Mar 23;111:33-45. doi: 10.1016/j.ejmech.2016.01.022. Epub 2016 Jan 21.

PMID:
26854376
8.

The role of microenvironment and immunity in drug response in leukemia.

Bakker E, Qattan M, Mutti L, Demonacos C, Krstic-Demonacos M.

Biochim Biophys Acta. 2016 Mar;1863(3):414-426. doi: 10.1016/j.bbamcr.2015.08.003. Epub 2015 Aug 6. Review.

9.

Cytochrome P450 2E1 (CYP2E1) regulates the response to oxidative stress and migration of breast cancer cells.

Leung T, Rajendran R, Singh S, Garva R, Krstic-Demonacos M, Demonacos C.

Breast Cancer Res. 2013 Nov 8;15(6):R107. doi: 10.1186/bcr3574.

10.

Acetylation mediated by the p300/CBP-associated factor determines cellular energy metabolic pathways in cancer.

Rajendran R, Garva R, Ashour H, Leung T, Stratford I, Krstic-Demonacos M, Demonacos C.

Int J Oncol. 2013 Jun;42(6):1961-72. doi: 10.3892/ijo.2013.1907. Epub 2013 Apr 17.

PMID:
23591450
11.

Regulation of CXCR4 gene expression in breast cancer cells under diverse stress conditions.

Andreou K, Rajendran R, Krstic-Demonacos M, Demonacos C.

Int J Oncol. 2012 Dec;41(6):2253-9. doi: 10.3892/ijo.2012.1643. Epub 2012 Sep 27.

PMID:
23023398
12.

Roadmap to personalized medicine.

Qattan M, Demonacos C, Krstic-Demonacos M.

Croat Med J. 2012 Aug;53(4):294-7.

13.

myo-Inositol esters of indomethacin as COX-2 inhibitors.

Kadirvel M, Abudalal AS, Rajendran R, Gbaj A, Demonacos C, Freeman S.

Carbohydr Res. 2012 Jul 1;355:13-8. doi: 10.1016/j.carres.2012.04.008. Epub 2012 Apr 20.

PMID:
22578527
14.

Sirtuins: molecular traffic lights in the crossroad of oxidative stress, chromatin remodeling, and transcription.

Rajendran R, Garva R, Krstic-Demonacos M, Demonacos C.

J Biomed Biotechnol. 2011;2011:368276. doi: 10.1155/2011/368276. Epub 2011 Sep 7. Review.

15.

Regulation of glucocorticoid receptor activity by a stress responsive transcriptional cofactor.

Davies L, Paraskevopoulou E, Sadeq M, Symeou C, Pantelidou C, Demonacos C, Krstic-Demonacos M.

Mol Endocrinol. 2011 Jan;25(1):58-71. doi: 10.1210/me.2010-0212. Epub 2010 Dec 8.

16.

Quantitative analysis and modeling of glucocorticoid-controlled gene expression.

Chen DW, Lynch JT, Demonacos C, Krstic-Demonacos M, Schwartz JM.

Pharmacogenomics. 2010 Nov;11(11):1545-60. doi: 10.2217/pgs.10.125.

PMID:
21121775
17.

Delivery of therapeutic shRNA and siRNA by Tat fusion peptide targeting BCR-ABL fusion gene in Chronic Myeloid Leukemia cells.

Arthanari Y, Pluen A, Rajendran R, Aojula H, Demonacos C.

J Control Release. 2010 Aug 3;145(3):272-80. doi: 10.1016/j.jconrel.2010.04.011. Epub 2010 Apr 24.

PMID:
20403398
18.

Site-specific and dose-dependent effects of glucocorticoid receptor phosphorylation in yeast Saccharomyces cerevisiae.

Popovic N, Ruzdijic S, Kanazir DT, Niciforovic A, Adzic M, Paraskevopoulou E, Pantelidou C, Radojcic M, Demonacos C, Krstic-Demonacos M.

Steroids. 2010 Jun;75(6):457-65. doi: 10.1016/j.steroids.2010.03.001. Epub 2010 Mar 9.

19.

The role of glucocorticoid receptor phosphorylation in Mcl-1 and NOXA gene expression.

Lynch JT, Rajendran R, Xenaki G, Berrou I, Demonacos C, Krstic-Demonacos M.

Mol Cancer. 2010 Feb 15;9:38. doi: 10.1186/1476-4598-9-38.

20.

The role of phosphorylated glucocorticoid receptor in mitochondrial functions and apoptotic signalling in brain tissue of stressed Wistar rats.

Adzic M, Djordjevic A, Demonacos C, Krstic-Demonacos M, Radojcic MB.

Int J Biochem Cell Biol. 2009 Nov;41(11):2181-8. doi: 10.1016/j.biocel.2009.04.001. Epub 2009 Apr 9.

21.

Acute or chronic stress induce cell compartment-specific phosphorylation of glucocorticoid receptor and alter its transcriptional activity in Wistar rat brain.

Adzic M, Djordjevic J, Djordjevic A, Niciforovic A, Demonacos C, Radojcic M, Krstic-Demonacos M.

J Endocrinol. 2009 Jul;202(1):87-97. doi: 10.1677/JOE-08-0509. Epub 2009 Apr 30.

22.

PCAF is an HIF-1alpha cofactor that regulates p53 transcriptional activity in hypoxia.

Xenaki G, Ontikatze T, Rajendran R, Stratford IJ, Dive C, Krstic-Demonacos M, Demonacos C.

Oncogene. 2008 Oct 2;27(44):5785-96. doi: 10.1038/onc.2008.192. Epub 2008 Jun 23.

23.

Cross talk of signaling pathways in the regulation of the glucocorticoid receptor function.

Davies L, Karthikeyan N, Lynch JT, Sial EA, Gkourtsa A, Demonacos C, Krstic-Demonacos M.

Mol Endocrinol. 2008 Jun;22(6):1331-44. doi: 10.1210/me.2007-0360. Epub 2008 Mar 12.

24.

A new effector pathway links ATM kinase with the DNA damage response.

Demonacos C, Krstic-Demonacos M, Smith L, Xu D, O'Connor DP, Jansson M, La Thangue NB.

Nat Cell Biol. 2004 Oct;6(10):968-76. Epub 2004 Sep 19.

PMID:
15448695
25.

Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance.

Erler JT, Cawthorne CJ, Williams KJ, Koritzinsky M, Wouters BG, Wilson C, Miller C, Demonacos C, Stratford IJ, Dive C.

Mol Cell Biol. 2004 Apr;24(7):2875-89.

26.

Drug discovery and the p53 family.

Demonacos C, La Thangue NB.

Prog Cell Cycle Res. 2003;5:375-82. Review.

PMID:
14593732
27.

A TPR motif cofactor contributes to p300 activity in the p53 response.

Demonacos C, Krstic-Demonacos M, La Thangue NB.

Mol Cell. 2001 Jul;8(1):71-84.

28.

Acetylation control of the retinoblastoma tumour-suppressor protein.

Chan HM, Krstic-Demonacos M, Smith L, Demonacos C, La Thangue NB.

Nat Cell Biol. 2001 Jul;3(7):667-74.

PMID:
11433299
29.

Using yeast to study glucocorticoid receptor phosphorylation.

Pocuca N, Ruzdijic S, Demonacos C, Kanazir D, Krstic-Demonacos M.

J Steroid Biochem Mol Biol. 1998 Sep;66(5-6):303-18.

PMID:
9749836
30.

Mitochondrial genes as sites of primary action of steroid hormones.

Demonacos CV, Karayanni N, Hatzoglou E, Tsiriyiotis C, Spandidos DA, Sekeris CE.

Steroids. 1996 Apr;61(4):226-32.

PMID:
8733006
32.

Import of the glucocorticoid receptor into rat liver mitochondria in vivo and in vitro.

Demonacos C, Tsawdaroglou NC, Djordjevic-Markovic R, Papalopoulou M, Galanopoulos V, Papadogeorgaki S, Sekeris CE.

J Steroid Biochem Mol Biol. 1993 Sep;46(3):401-13.

PMID:
9831490

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